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Online Gambling Addiction in Parakou (Benin, 2022)

中国植物保护学会第十一次全国会员代表大会暨2013年学术年会

作者：范佳张勇 Frederic francis 程登发孙京瑞夏兰琴陈巨莲中国农业科学院植物保护研究所植物病虫害生物学国家重点实验室 Functional and Evolutionary Entomology Gembloux Agro-Bio TechUniversity of LiegePassage des Deportes 2B-5030 GemblouxBelgium 中国农业科学院作物科学研究所

蚜虫是重要的农业害虫之一,其信息素识别及短程的寄主定位等均依赖灵敏的嗅觉。解析蚜虫的嗅觉将为开辟新型蚜害防控策略提供思路。嗅觉信号需要借助昆虫嗅觉受体复合体(ORs)完成向生理电信号的转导。Ors复合体由嗅觉受体(OR)和1个嗅觉... 详细信息

蚜虫是重要的农业害虫之一,其信息素识别及短程的寄主定位等均依赖灵敏的嗅觉。解析蚜虫的嗅觉将为开辟新型蚜害防控策略提供思路。嗅觉信号需要借助昆虫嗅觉受体复合体(ORs)完成向生理电信号的转导。Ors复合体由嗅觉受体(OR)和1个嗅觉受体伴随受体(Orco)组成。其中,Orco在不同种间高度保守,为昆虫特异表达蛋白,伴随各种OR共表达。报警信息素(E-B-farnesene,EBF)不但引起对蚜虫的嗅觉反应,对后代有翅蚜的诱导被推测也是由嗅觉感受系统介导的。本研究从麦长管蚜触角中克隆获得1个Orco基因,命名为"SaveOrco"。饲喂siRNA后,麦长管蚜SaveOrco的表达水平下降64%,对包括绿叶气味、报警信息素、蚜害诱导挥发物在内的多种气味的触角电位反应显著减弱(P<0.01)。对处于"出生前期"和"初生期"的麦长管蚜进行报警信息素的释放处理会显著提高有翅蚜比例(P<0.01),SaveOrco被RNAi沉默后,麦长管蚜不再响应上述诱导。综上所述,SaveOrco对于麦长管蚜的嗅觉感受十分重要,EBF对麦长管蚜有翅蚜的诱导作用也是通过SaveOrco介导的;EBF诱导引起麦长管蚜有翅蚜的比例上升,响应该诱导的时期有两个,分别是"出生前期"和"初生期"。

关键词：蚜虫嗅觉受体触角电位翅型分化

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Open Journal of Psychiatry 2023年第S1期13卷 421-437页

作者： Ataigba Ireti Nethania Elie Soumaoro Kemo Koivogui David Sinet moussa Djibrilla Ousseyni Zika Oumou Awanou Yabo Elodie Djossou Sègnon Eurydice Elvire Tokpanoude Coovi Nonwanou Ignace Djidonou Anselme Tognon Tchegnonsi francis Gandaho Prosper Ezin Houngbe Josiane Faculté de médecine & Institut de Formation en Soins Infirmiers et Obstétricaux Université de Parakou Parakou Benin Service de Psychiatrie Centre Hospitalier Universitaire Départemental du Borgou Alibori Parakou Benin Organisation Non Gouvernementale de Soutien de Réhabilitation d’Insertion et de Réinsertion (SouRIR ONG) Parakou Benin Faculté des Sciences et Techniques de Santé Université Gamal Abdel Nasser de Conakry Conakry Guinea Service de Psychiatrie H&#244pital National Donka CHU de Conakry Conakry Guinea Faculté des Sciences de la Santé Université André Salifou de Zinder Zinder Niger Service de Psychiatrie H&#244pital National de Zinder Zinder Niger Faculté des Sciences de la Santé Université Abdou Moumouni de Niamey Niamey Niger Service de Psychiatrie H&#244pital National de Niamey Niamey Niger Faculté des Sciences de la Santé Unité de Santé Publique Cotonou Benin Faculté des Sciences de la Santé Université d’Abomey-Calavi Abomey-Calavi Benin Service de Psychiatrie Centre National Hospitalier Universitaire - Hubert Koutoucou Maga de Cotonou Cotonou Benin

Introduction: Online gambling is becoming increasingly popular worldwide. With its well-crafted visual and audio marketing, it is attracting more and more young people in Africa, where problems linked to employment and poverty are undermining youth. The consequences of gaming-related practices for health in general, and mental health in particular, are not negligible. The aim of this study was to measure the extent of the phenomenon within an urban community in Benin. methods: Descriptive cross-sectional study with analytical aim conducted in the general population of Parakou, northern Benin, from December 2021 to November 2022. A self-administered questionnaire incorporating DSm 5 criteria for pathological gambling was used to collect data. Results: A total of 576 subjects divided into 30 clusters of 19 to 20 individuals consented to participate in the study. The proportion of gamblers was 30.56%. The prevalence of pathological gambling calculated according to DSm 5 criteria was 24.65% [21.31% - 28.33%] in the general population. The prevalence of severe pathological gambling was estimated at 8.16% [5.96% - 10.44%] in the general population. The prevalence of anxiety was 28.30% ([24.62% - 31.98%]), compared with 15.10% ([12.18% - 18.02%]) for depression. Factors with a significant association with pathological gambling were: age, access to online gambling, access to video games, exposure to gambling advertisement, having gambling friends, debt accumulation. A statistically significant link was also found between pathological gambling and anxiety/depression. Conclusion: The reality of pathological gambling in northern Benin calls for effective preventive action among vulnerable groups at national level, involving various actors at different levels.

关键词： Gambling Chance money Online Benin 2022

Physical exam:where’s the evidence?A medical student's experience

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Family medicine and Community Health 2020年第1期8卷 50-52页

作者： Scott m Seki Katharine C DeGeorge margaret L Plews-Ogan Andrew S Parsons University of Virginia School of medicine CharlottesvilleVirginiaUSA Department of Family medicine University of VirginiaCharlottesvilleVirginiaUSA Department of medicine University of VirginiaCharlottesvilleVirginiaUSA

It was not so long ago that an attending physician accused me of the following:‘you’re advocating for the elimination of the physical exam from medicine!’We were on rounds and debating the objectivity and merit of a single observer non-blinded prestudy/poststudy,the Bush-francis Catatonia Scale,as a means of measuring clinical status after an Ativan challenge.‘The kind of improvement you all are expecting is so obvious that the scale becomes obsolete’,I argued,‘And furthermore,in the gray area,improvements based on the scoring system don’t seem to approximate improvements in patient symptoms’.

关键词： furthermore elimination exam

接受溶栓治疗的ST段抬高心肌梗死患者行经皮冠状动脉介入术前氯吡格雷预处理的作用:PCI-CLARITY研究

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世界核心医学期刊文摘(心脏病学分册) 2006年第2期 19-20页

作者： Sabatine m. S. Cannon C. P. Gibson C. m. 王亭忠 Sabatine Cardiovascular Division TIMI Study Group Brigham and Women' s Hospital 75 Francis St Boston MA 02115 United States Dr.

Context: The benefit of clopidogrel pretreatment before percutaneous coronary intervention(PCI) remains debated and its use has not been universally adopted. Objective: To determine if clopidogrel pretreatment before PCI in patients with recent ST-segment elevation myocardial infarction(STEmI) is superior to clopidogrel treatment initiated at the time of PCI in preventing major adverse cardiovascular events. Design, Setting, and Participants: The PCI-Clopidogrel as Adjunctive Reperfusion Therapy(CLARITY) study was a prospectively planned analysis of the 1863 patients undergoing PCI after mandated angiography in CLARITY-Thrombolysis in myocardial Infarction(TImI) 28, a randomized, double-blind, placebo-controlled trial of clopidogrel in patients receiving fibrinolytics for STEmI. Patients were enrolled at 319 sites in 23 countries from February 2003 through October 2004. Interventions: Patients received aspirin and were randomized to receive either clopidogrel(300 mg loading dose, then 75 mg once daily) or placebo initiated with fibrinolysis and given until coronary angiography, which was performed 2 to 8 days after initiation of the study drug. For patients undergoing coronary artery stenting, it was recommended that open-label clopidogrel(including a loading dose) be administered after the diagnostic angiogram. main Outcome measures: The primary outcome was the incidence of the composite of cardiovascular death, recurrent mI, or stroke from PCI to 30 days after randomization. Secondary outcomes included mI or stroke before PCI and the aforementioned composite from randomization to 30 days. Results: Pretreatment with clopidogrel significantly reduced the incidence of cardiovascular death, mI, or stroke following PCI(34 3.6% vs 58 6.2% ; adjusted odds ratio OR , 0.54 95% CI, 0.35-0.85 ; P=.008). Pretreatment with clopidogrel also reduced the incidence of mI or stroke prior to PCI(37 4.0% vs 58 6.2% ; OR, 0.62 95% CI, 0.40-0.95 ; P=.03). Overall, pretreatment with clo

关键词：溶栓治疗氯吡格雷 PCI-CLARITY 经皮冠状动脉介入术 ST 预处理前处理

Cybersex Addiction in Benin Schools (2023)

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Open Journal of Psychiatry 2023年第S1期13卷 438-460页

作者： Ataigba Ireti Nethania Elie Soumaoro Kemo Koivogui David Sinet Ayena Fidèle moussa Djibrilla Ousseyni Zika Oumou Djossou Sègnon Eurydice Elvire Tokpanoude Coovi Nonwanou Ignace Sourabie Oumar Djidonou Anselme Tognon Tchegnonsi francis Gandaho Prosper Ezin Houngbe Josiane Faculté de médecine & Institut de Formation en Soins Infirmiers et Obstétricaux Université de Parakou Parakou Benin Service de Psychiatrie Centre Hospitalier Universitaire Départemental du Borgou Alibori Parakou Benin Organisation Non Gouvernementale de Soutien de Réhabilitation d’Insertion et de Réinsertion (SouRIR ONG) Parakou Benin Faculté des Sciences et Techniques de Santé Université Gamal Abdel Nasser de Conakry Conakry Guinea Service de Psychiatrie H&#244pital National Donka CHU de Conakry Conakry Guinea Faculté des Sciences de la Santé Université André Salifou de Zinder Zinder Niger Service de Psychiatrie H&#244pital National de Zinder Zinder Niger Faculté des Sciences de la Santé Université Abdou Moumouni de Niamey Niamey Niger Service de Psychiatrie H&#244pital National de Niamey Niamey Niger Faculté des Sciences de la Santé Unité de Santé Publique Cotonou Benin Service de Psychiatrie Centre Hospitalier Universitaire Sour&#244 Sanou Bobo-Dioulasso Burkina Faso Faculté des Sciences de la Santé Université d’Abomey-Calavi Abomey-Calavi Benin Service de Psychiatrie Centre National Hospitalier Universitaire - Hubert Koutoucou Maga de Cotonou Cotonou Benin

Introduction: The development of digital technology over the last few decades has facilitated access to websites and videos in the field of sexuality, eliminating many of the boundaries that were restrictive for some and protective for others. While this evolution has favored better information sharing, it has also precipitated the emergence of an entirely new phenomenon: cybersexuality. Objective: The aim of this study was to investigate addiction to cybersexuality in schools in the city of Parakou in 2023. methods: Descriptive cross-sectional study conducted in general, technical and vocational secondary schools in Parakou, northern Benin, from December 2022 to September 2023. A self-administered questionnaire integrating the “short Internet sex Addiction Test” (s-IATsex) scale was used to assess cybersexuality. Results: A total of 482 students participated in the study. The prevalence of problematic use of cybersexuality in Parakou schools was 11.4% according to the s-IATsex (Short Internet sex Addiction Test) scale. The average age of the students was 16.99 ± 2.16 years, with extremes of 11 and 30 years. The majority were in secondary school (67.8%). Factors associated with addiction to cybersexuality were: place of residence (OR = 0.164;p = 0.017), external genitalia discharge (OR = 5.37;p = 0.049), sexual partner (OR = 2.53;p = 0.010), access to pornographic sites (OR = 7.96;p mately one pupil in 10 is addicted to cybersexuality at school in the town of Parakou/Parakou city, Benin. The multiple consequences of this addiction call for effective preventive actions aimed at vulnerable groups of pupils.

关键词： Cybersex Addiction Students Benin 2023

Distinct clinical characteristics and helminth co-infections in adult tuberculosis patients from urban compared to rural Tanzania

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Infectious Diseases of Poverty 2018年第1期7卷 243-254页

作者： George Sikalengo Jerry Hella francis mhimbira Liliana K.Rutaihwa Farida Bani Robert Ndege mohamed Sasamalo Lujeko Kamwela Khadija Said Grace mhalu Yeromin mlacha Christoph Hatz Stefanie Knopp Sebastien Gagneux Klaus Reither Jurg Utzinger marcel Tanner Emilio Letang maja Weisser Lukas Fenner Ifakara Health Institute Dar es SalaamTanzania Swiss Tropical and Public Health Institute BaselSwitzerland' University of Basel BaselSwitzerland Institute of Social and Preventive medicine University of BernBernSwitzerland

Background:Differences in rural and urban settings could account for distinct characteristics in the epidemiology of tuberculosis(TB).We comparatively studied epidemiological features of TB and helminth co-infections in adult patients from rural and urban settings of ***:Adult patients(≥18 years)with microbiologically confirmed pulmonary TB were consecutively enrolled into two cohorts in Dar es Salaam,with~4.4 million inhabitants(urban),and Ifakara in the sparsely populated Kilombero District with~400000 inhabitants(rural).Clinical data were obtained at *** and urine samples were subjected to diagnose helminthiases using Kato-Katz,Baermann,urine filtration,and circulating cathodic antigen *** between groups were assessed byχ2,Fisher’s exact,and Wilcoxon rank sum *** regression models were used to determine ***:Between August 2015 and February 2017,668 patients were enrolled,460(68.9%)at the urban and 208(31.1%)at the rural *** patient age was 35 years(interquartile range[IQR]:27-41.5 years),and 454(68%)were *** from the rural setting were older(median age 37 years vs.34 years,P=0.003),had a lower median body mass index(17.5 kg/m2 vs.18.5 kg/m2,Pmedian CD4 cell counts(147 cells/μl vs.249 cells/μl,P=0.02)compared to those from urban *** was no significant difference in frequencies of HIV infection,diabetes mellitus,and haemoglobin concentration levels between the two *** overall prevalence of helminth co-infections was 22.9%(95%confidence interval[CI]:20.4-27.0%).The significantly higher prevalence of helminth infections at the urban site(25.7%vs.17.3%,P=0.018)was predominantly driven by Strongyloides stercoralis(17.0%vs.4.8%,Pma mansoni infection(4.1%vs.16.4%,P<0.001).Recurrent TB was associated with living in a rural setting(adjuste

关键词： Co-infection Helminth infection Recurrent tuberculosis Schistosomiasis Tanzania Tubercu

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Sustainable strategies for Ebola virus disease outbreak preparedness in Africa:a case study on lessons learnt in countries neighbouring the Democratic Republic of the Congo

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Infectious Diseases of Poverty 2022年第6期11卷 60-69页

作者： Caroline S.Ryan marie‑Roseline D.Belizaire miriam Nanyunja Olushayo Oluseun Olu Yahaya Ali Ahmed Anderson Latt matthew Tut Kol Bertrand Bamuleke Jayne Tusiime Nadia Nsabimbona Ishata Conteh Shamiso Nyashanu Patrick Otim Ramadan Solomon Fisseha Woldetsadik Jean‑Pierre mulunda Nkata Jim T.Ntwari Senya D.Nzeyimana Leopold Ouedraogo Georges Batona Vedaste Ndahindwa Elizabeth A.mgamb magdalene Armah Joseph francis Wamala Argata Guracha Guyo Alex Yao Sokemawu Freeman Alexander Chimbaru Innocent Komakech muhau Kuku Walter m.Firmino Grace E.Saguti Faraja msemwa Shikanga O‑Tipo Precious C.Kalubula Ngoy Nsenga Ambrose Otau Talisuna WHO Sub-Regional Ofce for Africa NairobiKenya WHO Country Ofce BanguiCentral African Republic WHO Country Ofce JubaSouth Sudan WHO Regional Ofce for Africa BrazzavilleCongo WHO Sub-Regional Ofce for Africa DakarSenegal Africa Centres for Disease Control and Prevention Addis AbabaEthiopia WHO Country Ofce BrazzavilleCongo WHO Coun‑try Ofce BujumburaBurundi WHO Country Ofce AsmaraEritrea WHO Country Ofce KigaliRwanda WHO Country Ofce KampalaUganda WHO Country Ofce LuandaAngola WHO Country Ofce Dar Es SalaamTanzania WHO Country Ofce LusakaZambia

Background: From may 2018 to September 2022, the Democratic Republic of Congo (DRC) experienced seven Ebola virus disease (EVD) outbreaks within its borders. During the 10th EVD outbreak (2018–2020), the largest experienced in the DRC and the second largest and most prolonged EVD outbreak recorded globally, a WHO risk assessment identified nine countries bordering the DRC as moderate to high risk from cross border importation. These countries implemented varying levels of Ebola virus disease preparedness interventions. This case study highlights the gains and shortfalls with the Ebola virus disease preparedness interventions within the various contexts of these countries against the background of a renewed and growing commitment for global epidemic preparedness highlighted during recent World Health Assembly *** text: Several positive impacts from preparedness support to countries bordering the affected provinces in the DRC were identified, including development of sustained capacities which were leveraged upon to respond to the subsequent coronavirus disease 2019 (COVID-19) pandemic. Shortfalls such as lost opportunities for operationalizing cross-border regional preparedness collaboration and better integration of multidisciplinary perspectives, vertical approaches to response pillars such as surveillance, over dependence on external support and duplication of efforts especially in areas of capacity building were also identified. A recurrent theme that emerged from this case study is the propensity towards implementing short-term interventions during active Ebola virus disease outbreaks for preparedness rather than sustainable investment into strengthening systems for improved health security in alignment with IHR obligations, the Sustainable Development Goals and advocating global policy for addressing the larger structural determinants underscoring these ***: Despite several international frameworks established at the global level for e

关键词： Ebola virus disease Emergency preparedness and response Lessons learned Case study International Health Regulations Democratic Republic of the Congo

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mR水脂分离成像评估左室心肌梗死后心肌脂肪沉积

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国际医学放射学杂志 2009年第6期 582-583页

作者： J.W.Goldfarb m.Roth 周淑琴 Department of Research and Education DeMatteis MRISt.Francis Hospital100 Port Washington BlvdRoslynNY 11576USA

目的利用mR水脂分离成像技术前瞻性评估慢心肌梗死(mI)病人左室(LV)心肌脂肪沉积发生率;并分LV心肌脂肪沉积与疤痕的特点、心肌局部及整体功能的系。材料与方法此项HIPAA-依从性研究经过伦理委员会准并获得所有受检者知情同意。采用1.5T

关键词：水脂分离心肌梗死脂肪沉积 mR 心肌

胰腺导管腺癌放射学报告模版:腹部放射协会和美国胰腺癌协会的共识声明

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国际医学放射学杂志 2014年第2期 167-167页

作者： m.m.Al-Hawary I.R.francis S.T.Chari E.K.Fishman D.m.Hough D.S.Lu 余晓 Department of Radiology University of Michigan Health System 1500 E Medical Center Dr University Hospital Room B1 D502 Ann ArborMI 48109

目的胰腺导管腺癌是一种具有侵袭性的、高死亡率的恶性肿瘤。通过放射学检查对其进行分期来合理判断疾病的严重程度是制定治疗方案的重要步骤。考虑到医生在专

关键词：胰腺导管腺癌胰腺癌腹部躯干放射学美国美利坚合众国北美洲声明