检索结果-南通市图书馆

Role of one-step nucleic acid amplification in colorectal cancer lymph node metastases detection

World Journal of Gastroenterology 2022年第30期28卷 4019-4043页

作者： francesco crafa Serafino Vanella Onofrio A Catalano Kelsey L Pomykala Mario Baiamonte Division of General and Surgical Oncology St.Giuseppe Moscati HospitalCenter of National Excellence and High SpecialtyAvellino 83100Italy Department of Radiology Athinoula A.Martinos Center for Biomedical ImagingMassachusetts General HospitalHarvard Medical SchoolBostonMA 02114United States Department of Nuclear Medicine Department of Radiological SciencesDavid Geffen School of Medicine at University of CaliforniaLos AngelesUniversity Hospital EssenUniversity of Duisburg-EssenEssen 45141Germany

Current histopathological staging procedures in colorectal cancer(CRC)depend on midline division of the lymph nodes(LNs)with one section of hematoxylin and eosin *** cells outside this transection line may be missed,which could lead to understaging of Union for International Cancer Control Stage II high-risk *** one-step nucleic acid amplification(OSNA)assay has emerged as a rapid molecular diagnostic tool for LN metastases *** is a molecular technique that can analyze the entire LN tissue using a reversetranscriptase loop-mediated isothermal amplification reaction to detect tumorspecific cytokeratin 19 *** findings suggest that the OSNA assay has a high diagnostic accuracy in detecting metastatic LNs in CRC and a high negative predictive *** is a standardized,observer-independent technique,which may lead to more accurate *** has been suggested that in stage II CRC,the upstaging can reach 25%and these patients can access postoperative adjuvant ***,intraoperative OSNA sentinel node evaluation may allow early CRC to be treated with organ-preserving surgery,while in more advanced-stage disease,a tailored lymphadenectomy can be performed considering the presence of aberrant lymphatic drainage and skip metastases.

关键词： Colorectal malignancies One-step nucleic acid amplification Diagnostic accuracy Negative predictive value Upstaging Organ-sparing surgery Tailored lymphadenectomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Non-exposed endoscopic wall-inversion surgery with one-step nucleic acid amplification for early gastrointestinal tumors:Personal experience and literature review

引用

World Journal of Gastroenterology 2023年第24期29卷 3883-3898页

作者： francesco crafa Serafino Vanella Aristide Morante Onofrio A Catalano Kelsey L Pomykala Mario Baiamonte Maria Godas Alexandra Antunes Joaquim Costa Pereira Valentina Giaccaglia Division of General and Surgical Oncology St.Giuseppe Moscati HospitalCenter of National Excellence and High SpecialtyAvellino 83100Italy Division of Gastorenterology and Endoscopy St.Giuseppe Moscati HospitalCenter of National Excellence and High SpecialtyAvellino 83100Italy Department of Radiology Athinoula A Martinos Center for Biomedical ImagingMassachusetts General HospitalHarvard Medical SchoolBostonMA 02114United States Department of Nuclear Medicine Department of Radiological SciencesUniversity Hospital EssenUniversity of Duisburg-EssenEssen 45141Germany Department of General Surgery Braga HospitalBraga 4710-243Portugal Department of Surgery Medclinic City HospitalDubai 505004United Arab Emirates

BACKGROUND Laparoscopic and endoscopic cooperative surgery is a safe,organ-sparing surgery that achieves full-thickness resection with adequate *** studies have demonstrated the safety and efficacy of these ***,these techniques are limited by the exposure of the tumor and mucosa to the peritoneal cavity,which could lead to viable cancer cell seeding and the spillage of gastric juice or enteric liquids into the peritoneal ***-exposed endoscopic wallinversion surgery(NEWS)is highly accurate in determining the resection margins to prevent intraperitoneal contamination because the tumor is inverted into the visceral lumen instead of the peritoneal *** intraoperative assessment of the nodal status could allow stratification of the extent of ***-step nucleic acid amplification(OSNA)can provide a rapid method of evaluating nodal tissue,whilst nearinfrared laparoscopy together with indocyanine green can identify relevant nodal tissue *** To determine the safety and feasibility of NEWS in early gastric and colon cancers and of adding rapid intraoperative lymph node(LN)assessment with *** The patient-based experiential portion of our investigations was conducted at the General and Oncological Surgery Unit of the *** Moscati Hospital(Avellino,Italy).Patients with early-stage gastric or colon cancer(diagnosed via endoscopy,endoscopic ultrasound,and computed tomography)were *** lesions were treated by NEWS procedure with intraoperative OSNA assay between January 2022 and October *** were examined intraoperatively with OSNA and postoperatively with conventional *** analyzed patient demographics,lesion features,histopathological diagnoses,R0 resection(negative margins)status,adverse events,and follow-up *** were collected prospectively and analyzed *** A total of 10 patients(5 males and 5 females)with an average age of 70.4±4.5 years(range:62

关键词： Laparoscopic and endoscopic cooperative surgery Non-exposed endoscopic wall inversion surgery Early gastric cancer Early colorectal cancer Sentinel lymph node One-step nucleic acid amplification Endoscopic full-thickness resection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Multimodal treatments of “gallstone cholangiopancreatitis”

引用

World Journal of Gastrointestinal Endoscopy 2022年第7期14卷 467-470页

作者： Serafino Vanella Mario Baiamonte francesco crafa Division of General and Surgical Oncology St.Giuseppe Moscati HospitalCenter of National Excellence and High SpecialtyAvellino 83100Italy General and Emergency Surgery Unit Civico Benfratelli Di Cristina HospitalPalermo 90121Italy Oncological and General Surgery Unit St.Giuseppe Moscati HospitalCenter of National Excellence and High SpecialtyAvellino 83100Italy

Gallstone cholangiopancreatitis is a potentially life-threatening pathology which requires quick intervention involving endoscopists,interventional radiologists,anesthesiologists and surgeons in relation to clinical *** possibilities are varied,especially with current progress in advanced endoscopy,interventional radiology,and minimally invasive *** following treatments are available:endoscopic sphincterotomy(ES)with stone extraction followed by laparoscopic cholecystectomy;simultaneous endoscopic stone extraction with laparoscopic cholecystectomy(rendezvous technique);combined laparoscopic cholecystectomy and common bile duct(CBD)exploration;open CBD exploration;ES post-cholecystectomy;percutaneous placement of biliary drains for unstable patients,followed by percutaneous cholangioscopy;and lithotripsy with different approaches,including a laser and balloon dilation of the sphincter of *** technique has its strengths and weaknesses,and there is great discussion in the literature on choosing the ideal approach based on the patient’s clinical conditions.

关键词： Cholangiopancreatitis Common bile duct stones Endoscopic retrograde cholangiopancreatography Endoscopic sphincterotomy Laparoscopic common bile duct exploration Percutaneous

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Laparoscopic and endoscopic cooperative surgery for full-thickness resection and sentinel node dissection for early gastric cancer

引用

World Journal of Gastrointestinal Endoscopy 2022年第8期14卷 508-511页

作者： Serafino Vanella Maria Godas Joaquim Costa Pereira Ana Pereira Ivano Apicella francesco crafa Department of General and Oncology Surgery St.Giuseppe Moscati HospitalAvellino 83100Italy Department of General Surgery Hospital de BragaBraga 4710-243Portugal

The endoscopic submucosal dissection(ESD)technique has become the gold standard for submucosal tumors that have negligible risk of lymph node metastasis(LNM),due to its minimal invasiveness and ability to improve quality of ***,this technique is limited in stage T1 cancers that have a low risk of *** full thickness resection can be achieved with laparoscopic endoscopic cooperative surgery(LECS),which combines laparoscopic gastric wall resection and *** LECS,the surgical margins from the tumor are clearly achieved while performing organ-preserving *** overcome the limitation of classical LECS,namely the opening of the gastric wall during the procedure,which increases the risk of peritoneal tumor seeding,non-exposed endoscopic wall-inversion surgery was *** this full-thickness resection technique,contact between the intra-abdominal space and the intragastric space was eliminated.

关键词： Endoscopic submucosal dissection Laparoscopic endoscopic cooperative surgery Non-exposed endoscopic wall-inversion surgery Early gastric cancer Nodal basin evaluation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Minimally invasive colorectal surgery learning curve

引用

World Journal of Gastrointestinal Endoscopy 2022年第11期14卷 731-736页

作者： Serafino Vanella Enrico Coppola Bottazzi Giancarlo Farese Rosa Murano Adele Noviello Tommaso Palma Maria Godas francesco crafa Department of General and Oncology Surgery A.O.R.N.San Giuseppe MoscatiAvellino 83100Italy

The learning curve in minimally invasive colorectal surgery is a constant subject of discussion in the *** data likely reflects the varying degrees of each surgeon’s experience in colorectal,laparoscopic or robotic *** factors are necessary for a successful minimally invasive colorectal surgery training program,including:Compliance with oncological outcomes;dissection along the embryological planes;constant presence of an expert tutor;periodic discussion of the morbidity and mortality rate;and creation of a dedicated,expert team.

关键词： Learning curve Colorectal surgery Laparoscopy Robotic surgery Minimally invasive surgery Cusum method

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：