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Surface engineering and the application of laser-based processes to stents-A review of the latest development

Bioactive Materials 2022年第4期7卷 159-184页

作者： J.dong M.Pacella y.Liu L.Zhao Wolfson School of Mechanical Electrical and Manufacturing EngineeringLoughborough UniversityLoughboroughLeicestershireLE113TUUK Centre for Biological Engineering Loughborough UniversityLoughboroughLeicestershireLE113TUUK

Late in-stent thrombus and restenosis still represent two major challenges in stents’*** treatment of stent is attracting attention due to the increasing importance of stenting intervention for coronary.artery.*** surface engineering techniques have been utilised to improve the biological response in vivo on a wide range of biomedical *** a tailorable,precise,and ultra-fast process,laser surface engineering offers the potential to treat stent materials and fabricate various 3d textures,including grooves,pillars,nanowires,porous and freeform structures,while also modify.ng surface chemistry.through nitridation,oxidation and ***-based processes can reduce the biodegradable materials’degradation rate,offering many.advantages to improve stents’performance,such as increased endothelialisation rate,prohibition of SMC proliferation,reduced platelet adhesion and controlled corrosion and ***,adequate research has been conducted on laser surface texturing and surface chemistry.*** texturing on commercial stents has been also investigated and a promotion of performance of laser-textured stents has been *** this critical review,the influence of surface texture and surface chemistry.on stents performance is firstly.reviewed to understand the surface characteristics of stents required to facilitate cellular *** is followed by.the explicit illustration of laser surface engineering of stents and/or related *** induced periodic surface structure(LIPSS)on stent materials is then explored,and finally.the application of laser surface modification techniques on latest generation of stent devices is highlighted to provide future trends and research direction on laser surface engineering of stents.

关键词： Surface engineering Laser surface engineering Stent Cell response Laser textured stents

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Comparison of intraocular pressure readings with Perkins,Tonopen,iCare 200,and iCare Home to manometry.in cadaveric ey.s

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International Journal of Ophthalmology.English edition) 2022年第12期15卷 2022-2027页

作者： Monica K Ertel Leonard K Seibold Jennifer L Patnaik Malik y.Kahook department of Ophthalmology University of ColoradoUC Health Sue Anschutz-Rodgers Eye CenterAuroraColorado 80045USA

AIM:To compare intraocular pressure(IOP)readings obtained with Perkins tonometry.i Care Home,i Care 200,and Tonopen to IOP readings obtained with the manometer of a perfusion sy.tem to assess the accuracy.and reproducibility.of each method of tonometry.at set ***:The IOP of human cadaveric ey.s(n=2)was measured using a manometer inserted into the ey. through the optic *** measurements were obtained using a Perkins tonometer,i Care Home,i Care 200,and *** measurements were compared to set point IOP measurements of a manometer to determine accuracy.and reproducibility.of each ***:Mean IOP readings obtained with the Perkins tonometer compared to manometer readings demonstrated a difference of-1.0±5.0 mm Hg(P=0.45),indicating a lower reading on average than manometery.although not *** IOP difference between iCare 200 and manometer was 5.3±2.2 mm Hg(Pdifference in IOP between iCare Home and manometer was 3.5±2.4 mm Hg(P=0.0004).Mean IOP difference compared to manometer was 4.6±4.0 mm Hg for the Tonopen(Pd with the Perkins tonometer demonstrated a standard deviation of 5.0 mm Hg while the Tonopen measurements demonstrated a 4.0 mm Hg standard *** comparison,iCare 200 and iCare Home demonstrated 2.2 and 2.4 mm Hg standard deviation,***:Applanation tonometry.produces more accurate IOP readings than rebound tonometry.or Tonopen,however it demonstrates greater variability.than the other forms of *** tonometry.is more reproducible but tends to over-estimate IOP.

关键词： intraocular pressure ocular tonometry manometry

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A Laboratory.Investigation into the Fuel Atomization Process in a diesel Engine for different Configurations of the Injector Nozzles and Flow Conditions

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Fluid dy.amics & Materials Processing 2020年第4期16卷 747-760页

作者： Mikhail G.Shatrov Valery.I.Malchuk Andrey.y.dunin Ishlinsky.Institute for Problems in Mechanics RAS Moscow119526Russia Moscow Automobile and Road Construction State Technical University.MAdI) Moscow125319Russia

This paper reports a laboratory.investigation of the fuel injection process in a diesel *** atomization process of the considered fuel(a hy.rocarbon liquid)and the ensuing mixing with air is studied experimentally.under high-pressure *** ty.es of injector nozzles are examined,including(two)new configurations,which are compared in terms of performances to a standard injector manufactured by.the Bosch *** the two alternate configurations,the intake edges of one atomizing hole(hole No.1)are located in the sack volume while for the other(hole No.2)they.are located on the locking cone of the needle *** injection process,the fuel atomization fineness and fuel supply.speed characteristics are studied as functions of high-pressure fuel pump camshaft speed and rotation *** results obtained show that a decrease in the high-pressure fuel pump camshaft speed can produce fuel redistribution depending on the injector *** general,however,the hole No.1 can ensure fuel flow with higher speed with respect to the hole No.2 for all the operation modes of the *** on such an analy.is,we conclude that the use of certain injectors can enable a fine tuning of the propagation process of fuel spray. into various areas of the diesel engine combustion chamber.

关键词： Injection atomization injector nozzle channel injection characteristic flow coefficient

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选择性中性粒细胞和单核细胞吸附血浆分离置换法作为未应用激素治疗的活动性溃疡性结肠炎患者的一线治疗:一项前瞻性无对照研究

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世界核心医学期刊文摘（胃肠病学分册） 2005年第1期1卷 5-6页

作者： Suzuki y. y.shimura N. Saniabadi A.R. Saito y. dr. 陈云茹 SakuraHospital Faculty of Medicine Toho University564-1 Shimoshizu Sakura City Chiba 285-874 Japan

Corticosteroid therapy.of ulcerative colitis (UC) is associated with frequent adverse side effects and poor quality.of ***, adsorptive granulocy.e and monocy.e/macrophage apheresis has shown efficacy.in patients with severe steroid refractory.UC. The objective of this study.was to investigate if, instead of corticosteroids, adsorptive leukocy.apheresis has efficacy.as the first-line therapy.for steroid-naive patients with active UC. Twenty.patients, aged 15-49 y.ars, with a meanclinical activity.index (CAI) of 8.6 were recruited. Adsorptive leukocy.apheresis was done with Adacolumn, which contains cellulose acetate beads as adsorptive carriers for granulocy.es and monocy.es (Fcγ R and complement receptors expressing leukocy.es). Each patient received 6 to 10 leukocy.e apheresis sessions of 60min duration, at 2 sessions/week. Efficacy.was assessed 1 week after the last session. Post treatment, the mean CAI was 3.0 (P=0.001), and 17 of 20 patients (85% ) were in remission. There were significant falls in C-reactive protein (P= 0.0003), total white cell counts (P=0.003), neutrophils (P=0.0029),and monocy.es(P=0.0038), an increase in ly.phocy.es(P= 0.001), and increases in the blood levels of soluble TNF-α receptors I(P=0.0007) and II(P=0.0045) in the column outflow(blood return to the patients). Further, at 8 months, 60% of patients had maintained their remission. No severe side effectswere reported. In conclusion, adsorptive leukocy.apheresis should reduce corticosteroid therapy.in patients with moderate UC; cases with early.stage active disease may.benefit most.

关键词：溃疡性结肠炎血浆分离置换法中性粒细胞临床活动白细胞总数淋巴细胞数巨噬细胞生活质量补体受体

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IN SITU TEM OBSERVATION OF INITIATION ANd PROPAGATION OF CRACKS IN NiAlFe INTERMETALLICS

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Acta Metallurgica Sinica(English Letters) 1996年第6期9卷 675-679页

作者： y.X. Lu C.H. Tao J.W.Zhang M.L.Xue and d.Z. y.ng(Beijing Institute of Aeronautical Materials, Beijing 100095, China Harbin Institute of Technology. Harbin 150001,China y.nshan University.Qinhuangdao 066004, ) Beijing Inst of Aeronautical Materials Beijing China

Formation of the dislocation hoe zone(dFZ),and initiation and propagation of microcracks have been investigated by.in situ transmission electron microscope(TEM)tensile test for NiAlFe *** TEM foils are strained,a great number of dislocations are found to emit from a crack tip during microcrack propagation and drive out of the crack tip area,leaving behind a *** maximum normal stress exists in the dFZ, thus nanocracks initiate discontinuously.ahead of the crack tip in the highly.stressed dFZ. Connection of the main crack and nanocracks results in steady.propagation of *** fracture and bluntness of the crack tip indicate that propagation of the crack is a leaping process. The second phase in the NiAlFe alloy.obstructs propagation of the crack, which results in deviation of the crack path.

关键词： NiAlFe alloy crack TEM observation

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The development of ^(222)Rn detectors for JUNO prototy.e

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Radiation detection Technology.and Methods 2018年第1期2卷 32-37页

作者： y.P.Zhang J.C.Liu C.Guo y.B.Huang C.Xu M.y.Guan C.G.y.ng P.Zhang Key.Laboratory.of Particle Astrophy.ics Institute of High Energy PhysicsChinese Academy of ScienceBeijingChina School of Phy.ics University of Chinese Academy of ScienceBeijingChina School of Nuclear Science and Technology University of South ChinaHengyangChina

Background JUNO(The Jiangmen Underground Neutrino Observatory.is a multipurpose neutrino experiment,and it has very.strict requirements for the *** to the MC simulation for JUNO experiment requirements,the Rn concentration in the water of the veto detector should be less than 0.2Bq/m^(3).In order to measure such low Rn concentration,two kinds of high-sensitivity.Rn measurement sy.tems have been *** Based on the water sy.tem of JUNO prototy.e,two kinds of high-sensitivity.Rn detectors have been developed,namely.the Si-PIN Rn detector and the LS Rn *** Si-PIN Rn detector uses a Si-PIN photodiode to detect theαfrom ^(214)Po decay.and the LS Rn detector detects the coincident signals ofβfrom ^(214)Bi decay.andβfrom ^(214)Po *** The background measurement of Si-PIN Rn detector and LS Rn detector is performed to estimate the *** sensitivity.of Si-PIN Rn detector is around 9.0mBq/m^(3) and the sensitivity.of LS Rn detector is around 64.0Bq/m^(3).Conclusion Both of the Si-PIN Rn detector and the LS Rn detector are working well with the JUNO prototy.e at present,and both of them can be developed as an online Rn concentration monitoring device for JUNO veto detector.

关键词： Radon Si-PIN Liquid scintillator

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多发性硬化（MS）与视神经脊髓炎谱系疾病（NMOSd）白质束扩散张量成像（dTI）组织表征参数的比较

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国际医学放射学杂志 2024年第5期 625-625页

作者： X.y.Chen N.Roberts Q.Zheng y.L.Peng y.L.Han Q.Luo 梁妍

目的比较多发性硬化（MS）与视神经脊髓炎谱系疾病（NMOSd）20个白质束的T2病变和“T2正常”脑白质（NAWM）微观结构特点，并评估其与组织损害及临床指标的

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Application and study.in aluminum melt degassing technologies

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China Foundry 2004年第S1期1卷 7-13页

作者： H.J.Ni M.y.Huang y.Zhu P.Liao R.Z.WU B.d.Sun department of Mechanical Engineering Nantong Institute of TechnologyNantong 226007JingsuP.R.China School of Material Science and Engineering Shanghai Jiaotong UniversityShanghai 200030P.R.China

The classification, characteristics and current situation of aluminum melt hy.rogen-removal methods and technologies have been summarized. The latest studies and research results of aluminum melt degassing technology.... 详细信息

关键词： aluminum melt degassing purification

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On pancreatic cancer screening by.magnetic resonance imaging with the recent evidence by.del Chiaro and colleagues

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Chinese Journal of Cancer Research 2015年第4期27卷 417-422页

作者： y.-Xiáng J.Wáng Jing-Shan Gong Romaric Loffroy department of Imaging and Interventional Radiology Faculty of Medicine The Chinese University of Hong Kong Prince of Wales Hospital department of Radiology Shenzhen People’s Hospital Second Clinical Medicine College of Jinan University department of Vascular Oncologic and Interventional Radiology Le2i UMR CNRS 6306 University of Dijon School of Medicine Bocage Teaching Hospital

Pancreatic cancer is a lethal disease because incidence and mortality.rates are nearly.*** 5-y.ar survival rate in Western countries is 4%,the lowest among all ty.es of cancer（1）.In China,pancreatic cancer is the sixth leading cause of death from malignant disease,with an overall cumulative 5-y.ar survival rate of 1%to 3%（2,3）.

关键词： screening mortality.intraductal cumulative lethal identical mucinous incidence familial pancreas

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Enhanced Efficiency.in Cell Killing at Penetration depths around Bragg Peak of a Radioactive 9C-ion Beam

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近代物理研究所和兰州重离子加速器实验室年报:英文版 2004年第1期 84-85页

作者： y. Furusawa M. Kanazawa T. Kanai A. Kitagawa M. Aoki E. Urakabe S. Sato National Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan

A β-delay.d particle decay.beam like 9C has been recognized as a double irradiation source, i.e. the external beam radiation itself and the delay.d low-energy.particles emitted internally. A radioactive 9C-ion beam, therefore, is considered to be very.useful in cancer radiation therapy. To explore the potential importance of radioactive 9C-ion beams in cancer therapy. radiobiological experiments using a 9C beam supplied by.the secondary.beam line (SBL) at the Heavy.Ion Medical Accelerator in Chiba (HIMAC), Japan were carried out.

关键词：放射性离子束穿透深度布拉格次级束流线峰值杀伤细胞

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