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Clinical features of gastroesophageal reflux disease and erosive esophagitis:Insights from patients undergoing esophagogastroduodenoscopy in resource-limited ethiopia

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World Journal of Gastroenterology 2024年第34期30卷 3883-3893页

作者： firehiwot.a mengist.e Abate B Shewaye Abel T Tasamma Zekarias S Ayalew Department of Internal Medicine Addis Ababa UniversityAddis Ababa 1176Addis AbabaEthiopia Department of Internal Medicine Rheum Rheumatology and Internal Medicine Specialty ClinicAddis Ababa 1000Addis AbabaEthiopia Division of Gastroenterology and Hepatology Department of Internal MedicineAdera Medical and Surgical CenterAddis Ababa 1000Addis AbabaEthiopia

BACKGROUND Gastroesophageal reflux disease(GeRD)is a common disease worldwide with varying clinical presentations and risk *** data for Africa is lacking,but an increasing trend is expected due to demographic and epidemiological *** endoscopic studies for general gastrointestinal disorders have shown some patients with erosive esophagitis(ee),no studies in ethiopia have investigated the clinical characteristics,risk factors,and severity of GeRD using esophagogastroduodenoscopy(eGD).AIM To assess the clinical features of GeRD in ethiopian patients who underwent eGD and determine the severity and risk factors of *** We conducted a multicenter,retrospective cross-sectional study of 221 patients diagnosed with GeRD and endoscopic findings of ee at Trauma Associated Severe Hemorrhage and Amniotic Membrane Stem Cell between January 2019 and August *** were collected from electronic medical records and phone call *** used descriptive statistics and binary logistic regression analysis with SPSS version 26 to identify the association between variables with a statistical significance set at P valuee mean±SD age of the patients was 44.8(±15.9)years,with a male-to-female ratio of 1.6:*** most commonly reported symptom was epigastric pain(80.5%),followed by heartburn(43%).Los Angeles(LA)-A ee was diagnosed in 71.1%of patients,followed by LA-B(14.9%),LA-C(7.7%),and LA-D(5.9%).Multivariate analysis showed that age 50 or above,presence of bleeding,and endoscopic findings of duodenitis/duodenopathy were significantly associated with severe ee(Pe and Barrett’s esophagus were observed in 4.5%and 1.36%of patients with ee,*** Most of the patients had milder ee with fewer ***,severe ee was more prevalent in older patients and those with duodenitis/duodenopathy.

关键词： Gastroesophageal reflux disease erosive esophagitis Hiatal hernia esophagogastroduodenoscopy Heart burn

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