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Comparative evaluation of urolithiasis management options in patients with horseshoe kidney:A systematic review and meta-analysis

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当代泌尿学（英文） 2023年第3期17卷 193-205页

作者： Yazan Qaoud Merella Al Tali fiona boland Andrew Simpson Niall Davis Department of Surgery Royal College of Surgeons in Ireland(RCSI)DublinIreland Data Science Centre Royal College of Surgeons in Ireland(RCSI)DublinIreland RCSI Library Royal College of Surgeons in Ireland(RCSI)DublinIreland

Background:Horseshoe kidney is a rare congenital anomaly commonly complicated by *** shockwave litho-tripsy(ESWL),ureteroscopy(URS),and percutaneous nephrolithotomy(PCNL)are treatment options for horseshoe kidney *** aim of this systematic review is to compare the benefits and risks of these management options.Methods:MEDLINE,EMBASE,and Cochrane Library databases were searched from inception to February 2022.A total of 516 nonduplicate studies were screened against the inclusion and exclusion *** comparing at least 2 interventions with＞10 pa-tients per intervention were included.Results:Nine retrospective observational studies published from 2007 to 2021 with a total of 565 patients were *** mean±SD or mean(range)stone sizes ranged between 17.90±2.43 mm and 27.9±8.6 mm for PCNL,8.4(2-25)mm and 22.3±9.1 mm for URS,and 11.9±2.0 mm and 16.8±4.4 mm for *** was no difference in single-session and overall stone-free rate(SFR)between PCNL and URS,with a risk ratio of 1.04(95％confidence interval,0.95-1.13;I2=20.63％).Ureteroscopy had better stone clearance than ESWL,with an overall SFR risk ratio of1.38(95％confidence interval,1.04-1.82;I2=0％).There was no statistically significant difference in overall SFR between PCNL and *** patients who underwent URS and ESWL experienced Clavien-Dindo(CD)grade Ⅰ-Ⅱ *** nephrolithotomy was associated with the highest complication rates,includ-ing 5 CD grade Ⅲ and 3 CD grade Ⅳ complications and a mean postoperative hemoglobin drop of 0.47 to 1.83 g/*** were no CD grade V complications across all studies.Conclusions:There was no difference in SFR between PCNL and *** was associated with a smaller stone burden and fewer and less severe *** was found to be more effective than ESWL with a higher SFR and comparable safety *** large-scale randomized controlled trials are needed to confirm these fi

关键词： Conjoined kidneys Extracorporeal shockwave lithotripsy Horseshoe kidney Kidney stones Percutaneous nephrolithotomy Ureteroscopy

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Understanding Urban Vitality from the Economic and Human Activities Perspective:A Case Study of Chongqing,China

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Chinese Geographical Science 2024年第1期34卷 52-66页

作者： YANG fiona Fan LIN Geng LEI Yubing WANG Ying YI Zheng School of Geography and Planning Sun Yat-sen UniversityGuangzhou510006China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai519100China Chongqing Planning and Design Institute Chongqing401147China

The literature on urban vitality tends to focus on the built *** paper argues that some important processes in shaping vitality may be overlooked without examining the intensity and diversity of economic and human *** newly developed spatial big data and adopting the methods of multi-indicator measurement and spatial analysis methods,we analyzed the pattern of urban vitality in Chongqing,a provincial city in western China and,on this basis,evaluated the creation and maintenance of urban vitality from the economic and human activities *** findings indicate that the impacts of economic and human activities are positive and *** the three intensity and diversity indicators,economic intensity and population density show an effect on urban vitality stronger than that of economic ***,economic diversity has the strongest superposition or interactive effect,and is thus an important foundation *** positive effect of population density on urban vitality is largely a result of Chongqing’s jobs-housing *** case of Chongqing highlights the importance of topographic features,historical inheritance,large-scale migration,and cultural activities in shaping the distinctive vitality pattern of a *** study contends that the creation and maintenance of urban vitality can not be fully explained without incorporating the impacts of economic and human *** contributes to a comprehensive measurement of urban vitality and enriches its connotations.

关键词： urban vitality economic diversity economic intensity population density Chongqing,China

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A marathon,not a sprint:Increasing population physical activity as a legacy of sports mega-events

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Journal of Sport and Health Science 2024年第6期13卷 732-735页

作者： fiona C.Bull Paul J.Simpson Physical Activity Unit Department of Health PromotionWorld Health OrganizationGeneva CH-1211Switzerland The BMJ London WC1H 9JPUK

*** matters The withdrawal of Australia as hosts for the Commonwealth Games in 2026 demonstrates that large international sporting events are more than just sporting mastery,medals,and *** also matters.1 The cost of hosting a major international tournament is eye-wateringly *** governments need to show that the billions of dollars of investment deliver a return beyond sporting glory to justify the resources that are spent.

关键词： return dollar sport

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Extreme Weather Disruptions and Emergency Preparedness Among Older Adults in Ohio: An Eight-County Assessment

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International Journal of Disaster Risk Science 2024年第2期15卷 213-225页

作者： Smitha Rao fiona C.Doherty Anthony Traver Marisa Sheldon Emma Sakulich Holly Dabelko‑Schoeny College of Social Work The Ohio State UniversityColumbusOH 43210USA Age Friendly Innovation Center College of Social WorkThe Ohio State UniversityColumbusOH 43210USA College of Public Health The Ohio State UniversityColumbusOH 43210USA

The disproportionate risks and impacts of climate change and extreme weather on older adults are increasingly evident. While especially true in disaster-prone areas, human-caused climate change introduces an element of uncertainty even in previously identified “safe” regions such as the Midwestern United States. Using a cumulative disadvantage and vulnerability-informed framework and descriptive statistics from multiple data sources, this article provides an overview of climate impacts, vulnerabilities, and county-level characteristics, focusing on older adults living in Central Ohio. A comparative multiple-case study methodology was used to triangulate regionally representative primary and secondary data sources to examine state and county-level measures of vulnerability, emergency preparedness, and disruptions caused by extreme weather among older adults across eight counties in Central Ohio. Seventy-eight percent of older adults in the sample reported being prepared for emergencies per Federal Emergency Management Agency guidelines. Older adults in Union County reported the highest rates of preparedness, while those in Fayette County reported the lowest. County-level rates of disruption of life activities by extreme weather ranged widely. Among the most rural in the region, Fayette County emerged as uniquely disadvantaged, with the lowest median income, the most vulnerable across multiple social vulnerability dimensions, and the most reported disruptions to life activities from extreme weather. County profiles offer a snapshot of existing vulnerabilities, socioeconomic conditions, special needs, preparedness, and current disruptions among older adults in the region and can inform resource mobilization across community and policy contexts.

关键词： Disaster preparedness Extreme weather Midwestern United States Older adults Regional assessment Social vulnerability

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BIKAS:Bio-Inspired Knowledge Acquisition and Simulacrum-A Knowledge Database to Support Multifunctional Design Concept Generation

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Data Intelligence 2024年第2期6卷 531-558页

作者： Pavan Tejaswi Velivela Yaoyao fiona Zhao Department of Mechanical Engineering McGill UniversityQuebecCanada H3A 0G4

A detailed acquisition,analysis,and representation of biological systems exhibiting different functions is required to develop unique bio-inspired multifunctional conceptual designs and *** paper presents BIKAS:Bio-inspired Knowledge Acquisition and Simulacrum,a knowledge database of biological systems exhibiting various functionalities,developed based on case-based bio-inspired examples from *** knowledge database represents the biological features,their characteristics,and the function exhibited by the biological feature as a combination of its integrated structure and structural ***,this knowledge database is utilized by the Expandable Domain Integrated Design(xDID)model that works on classifying,mapping,and representing biological features into their respective geometric designations called *** combination of features from the Domains results in the generation of multifunctional conceptual *** addition,Meta-level design factors are proposed to aid designers in filtering the biological features and their respective functions having a similar structural strategy,thus aiding designers in rapidly selecting and emulating biological functions.

关键词： Bio-inspired design(BID) Knowledge database Conceptual design Multifunctional bio-inspired design Agile innovation

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颠覆传统设计美国药店寻找新的发展良方

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商业周刊（中文版） 2024年第8期 10-11页

作者： fiona Rutherford 融汐(译) 不详

●美国药店巨头沃尔格林正在颠覆经典的药店设计,将药房从后端移至最前端走进任何一家美国药店,看上去都是一样的:一排排上锁的柜子里摆满了牙膏、洗发水和化妆品。病人在药店的后端排队等候药物,那里的工作人员通常很少,忙碌的药剂师... 详细信息

●美国药店巨头沃尔格林正在颠覆经典的药店设计,将药房从后端移至最前端走进任何一家美国药店,看上去都是一样的:一排排上锁的柜子里摆满了牙膏、洗发水和化妆品。病人在药店的后端排队等候药物,那里的工作人员通常很少,忙碌的药剂师一边忙着咨询,一边忙着接电话。然而这样的做法还是不够。彭博(Bloomberg)最近报道称,美国最大的连锁药店CVS Health Corp.和沃尔格林(Walgreens Boots Alliance Inc.)的利润率正在下降。(后者开始继续尝试出售博姿国际连锁药店。)曾是这两家激烈竞争对手的来德爱公司(RiteAidCorp.)去年10月宣布破产。药店面临的一个关键问题在于店面前端,那里的竞争和通货膨胀使它们盈利难度更大了。

关键词：连锁药店洗发水通货膨胀利润率药剂师排队等候

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欧洲具有广阔的新电商市场

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现代广告 2024年第3期 36-41页

作者： fiona Liu Guillaume Loiseau 陆斌欧洲电商直播协会法国文艺复兴文化传播公司浙江财经大学

fiona Liu女士和Guillaume Loiseau接受本刊专访。他俩介绍,新冠期间欧洲市场已转向电商购物作为正常购买方式。在法国,KOL不是专业的销售人员,不能直接在平台销售产品。直播营销主要是通过促销代码机制重新引流到品牌网站进行交易。

关键词： KOL 促销代码引流品牌网站

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珠三角高科技企业与香港科技创新赋能的关联特征及影响因素

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地理学报 2024年第6期79卷 1521-1539页

作者：许吉黎叶嘉安林初昇刘行健杨帆罗子昕广东省科学院广州地理研究所广东省遥感与地理信息系统应用重点实验室广州510070 香港大学城市规划与设计系中国香港999077 香港大学地理系中国香港999077 中山大学地理科学与规划学院广州510006

珠三角与香港跨境区域创新系统建设是粤港澳大湾区迈向国际科技创新中心的重要支撑。本文聚焦珠三角高科技企业使用香港科技创新功能及要素的特征,集成客观视角下企业社会经济属性和主观视角下利益相关者合作动机以揭示影响因素。研究表... 详细信息

珠三角与香港跨境区域创新系统建设是粤港澳大湾区迈向国际科技创新中心的重要支撑。本文聚焦珠三角高科技企业使用香港科技创新功能及要素的特征,集成客观视角下企业社会经济属性和主观视角下利益相关者合作动机以揭示影响因素。研究表明:①香港地区对珠三角高科技企业的科创功能供给主要体现在“一国两制”框架制度优势的市场拓展、国际化运营和企业融资,投资创业退居相对次要位置,科创要素的供需关联性由强到弱分别是生产性服务、劳动力和科技;②港资、较大规模和创立年限更久的珠三角高科技企业更倾向使用香港科创要素,内资、中小规模和新创企业对香港科创要素的需求呈减弱态势;③香港地区劳动力、科技和生产性服务供给的优势体现在竞争力、国际接轨和国际视野,劣势在于高成本、粤港相互了解有待深化和合作机制不够健全;④宏观层面全球和国家新经济格局下香港地区的功能转型、中观层面“一国两制三关”跨境区域特性、微观层面企业异质性之间的多层级互动影响珠三角高科技企业与香港科技创新赋能的关联特征。

关键词：区域创新系统高科技产业粤港澳大湾区一国两制珠江三角洲香港地区

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Advances in acute and chronic pancreatitis

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World Journal of Gastroenterology 2023年第7期29卷 1194-1201页

作者： Williamson B Strum Clement Richard boland Department of Gastroenterology Scripps ClinicLa JollaCA 92037United States Department of Medicine University of California San DiegoLa JollaCA 92037United States

Acute pancreatitis(AP)and chronic pancreatitis are the third leading gastrointestinal causes for admissions and readmissions to hospitals in the United *** review of articles published between 2019-2022(December)from international sources identified four categories of crucial new findings:The report includes(1)New genetic pathogenic mutations(TRPV6);expected genetic outcomes in a Northern European population;(2)a new serum diagnostic marker for AP-fatty acid ethyl esters-distinguishing acute pancreatitis associated with alcohol;explanations of the impact of monocytes/macrophages on the inflammatory process that defines their future in diagnosis,staging,and treatment;(3)innovations in timing of per os low-fat,solid food intake immediately on admission;resolution of concepts of aggressive parenteral fluid intake;dramatic shifts to nonoperative from operative treatment of infected pancreatic *** modification reduced interventions,complications,and lengths-of-stay;and(4)authoritarian recommendations for medical treatment of chronic *** advances offer opportunities to initiate newly proven treatments to enhance outcomes,alter the natural history,and envision the future of two diseases that have no known cure.

关键词： Genetics New diagnostics Macrophage regulation New approaches to early feeding Fluid management

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“Role of exercise in preventing and restoring gut dysbiosis in patients with inflammatory bowel disease”:A letter to the editor

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World Journal of Gastroenterology 2022年第8期28卷 878-880页

作者： Neasa Mc Gettigan Aoibhlinn O'Toole Karen boland Department of Gastroenterology Beaumont HospitalDublin D09V2N0LeinsterIreland School of Medicine Royal College of SurgeonsDublin D02YN77Ireland

Exercise-induced changes of the microbiome in inflammatory bowel diseases(IBD)is a promising field of research with the potential for personalized exercise regimes as a promising therapeutic adjunct for restoring gut dysbiosis and additionally for regulating immunometabolic pathways in the management of IBD *** exercise programmes in IBD patients of at least of 12 wk duration are more likely to result in disease-altering changes in the gut microbiome and to harness potential anti-inflammatory effects through these changes along with immunometabolic pathways.

关键词： Inflammatory bowel diseases Microbiota Dysbiosis Metabolism Exercise Cytokines

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