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Accession ×Treatment Interaction, Variability and Correlation Studies of Pepper (<i>Capsicum</i>spp.) under the Influence of Arbuscular Mycorrhiza Fungus (<i>Glomus clarum</i>) and Cow Dung

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American Journal of Plant Sciences 2014年第5期5卷 683-690页

作者： Odunayo Joseph Olawuyi Segun Gbolagade Jonathan fikayo ezekiel babatunde Busayo Joshua Babalola Ola Oluwa Simon Yaya James Oludare Agbolade Daniel Ayandiran Aina Chike Joseph Egun Department of Agronomy College of Agriculture Osun State Uni-versity Ejigbo Campus Ejigbo Nigeria Department of Biosciences and Biotechnology Babcock University Lagos Nigeria Department of Plant Sciences and Biotechnology Federal University Oye-Ekiti Oye-Ekiti Nigeria Department of Statistics University of Ibadan Ibadan Nigeria Genetics & Molecular Biology Unit Department of Botany University of Ibadan Ibadan Nigeria Mycology & Biotechnology Unit University of Ibadan Ibadan Nigeria

The field experiment was conducted in the Department of Botany, University of Ibadan, Nigeria between September to December 2012. Four accessions of pepper (Capsicum spp.), obtained from Moor plantation in Ibadan and LUTH (Lagos University Teaching Hospital) vegetable garden, Idi-Araba Lagos were evaluated to investigate the morpho-agronomic variability and interaction of accession × treatment × days after transplant in treatment combinations of arbuscular mycorrhizal fungus (Glomus clarum) and cowdung. The experiment was a 4 × 4 factorial arrangement laid out in a randomized complete block design with three replications. The combined analysis of variance showed significant accession, treatment, days after transplant, and accession × treatment interactive effect for most of the growth characters at P 0.01 and P 0.05. The result also showed significant difference in yield related traits of fruits for pepper accessions. The number of leaves per plant was significant and positively associated with plant height (r = 0.516;P 0.05), and highly significant and positively correlated with the number of branches (r = 0.836;P 0.01), but negative and non-significantly related with stem girth. Glomus clarum treated plants responded significantly with higher growth and yield. It suggested that G. clarum treatment had higher potential in influencing crop yield compared to cowdung and untreated plants. This study further explored the relationship between G.

关键词： Capsicum Glomus clarum Cowdung Variability Yield

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Prevalence and Factors Associated with Hypertension among People Living with HIV Receiving Care in Three Large HIV Clinics in Nasarawa State, Nigeria

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World Journal of AIDS 2024年第1期14卷 1-17页

作者： Prosper Okonkwo Oluseye Ajayi Deborah babatunde Dimas Mercy ezekiel Program Department APIN Public Health Initiatives Abuja Nigeria Community Medicine Department Bingham University Karu Nigeria Prevention and Community Service Directorate APIN Public Health Initiatives Abuja Nigeria Health System Strengthening Directorate APIN Public Health Initiatives Abuja Nigeria

In the last decade, the long-term survival among people living with HIV (PLHIV) has significantly improved. This is accompanied by an increased burden of non-communicable diseases such as hypertension due to the combined effect of the aging population and the metabolic effect of the Human Immuno-deficiency Virus (HIV) virion and antiretroviral therapy. This study aims to assess the prevalence and factors associated with hypertension among people living with HIV in three large health facilities in Nasarawa State, Nigeria. A descriptive cross-sectional study employed a multistage sampling technique to select 309 adults with HIV, 18 years and above, receiving HIV care in three large health facilities in Nasarawa State. The outcome variable was the participants’ self-reported history of hypertension, confirmed through a positive history of hypertension treatment. Exposure variables included the participant’s socio-demographic characteristics, lifestyle factors, and HIV care and treatment history. Data were presented using frequency tables. Factors associated with hypertension were assessed using binary logistic regression at a 0.05 level of statistical significance. A total of 309 adults living with HIV were sampled. A larger percentage of the participants were married 228 (73.8%), female, 191 (61.8%), within the age group 41 - 50 years, 141 (45.6%). Most of the participants had no family history of hypertension, 188 (60.8%). The prevalence of self-reported hypertension was 11.0% (34/309). Factors associated with hypertension at the bivariate level were age group 21 - 30 years, 41 - 50 years, being widow/widower, divorced, retired from employment or with family history of hypertension. Only participants age group 31 - 40 years [Adjusted Odd Ratio (AOR): 0.18, 95%CI: 0.04 - 0.91, p = 0.04] and family history of hypertension [(AOR): 83.44, 95%CI: 15.75 - 442.11, p < 0.01] were found to predict hypertension among the study participants after adjusting for confounders. In c

关键词： HIV HIV Care Hypertension Hypertension Prevalence Nigeria PLHIV

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Contexts and pragmatic strategies of COVID-19 related cartoons in Nigeria

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Language and Semiotic Studies 2024年第2期10卷 267-289页

作者： ezekiel Opeyemi Olajimbiti Oluwafemi Bolanle Jolaoso Department of English and Literary Studies Federal University LokojaLokojaNigeria Department of English and Literary Studies Ladoke Akintola University of TechnologyOgbomosoNigeria

The global outbreak of the coronavirus pandemic has been experienced differently by people depending on their socio-cultural *** varied experiences are expressed in various forms of communication,including *** paper examines the pragmatic resources inherent in COVID-19-related cartoons depicting the impact of the virus on Nigerian *** COVID-19-related cartoons,circulated on social media,were collected on Twitter and WhatsApp platforms between March and April 2020 as *** and presupposition served as theoretical framework and descriptive research design was *** reveal five socio-contextual domains,religion,health,economy,politics and governance nd family,characterizing the social experiences of Nigerians during the *** the evocation of situational reality,pragmatic sarcasm,punning,and orientation to government insensitivity,the cartoonists evoke pragmatic functions of informing and warning about social behaviours in the religion,family and health domains;recreating situational realities on socioeconomic impacts in the domain of economy;and satirizing government policies and mocking politicians’insincerity in the domain of politics and governance on sociopolitical experiences of Nigerians before and during the *** study concludes cartoons are a strong means of portraying societal realities and people’s experiences comically and graphically.

关键词： multimodality COVID-19-related cartoons sociocultural experience shared situational knowledge context

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Prevalence and Factors Associated with Hypertension among People Living with HIV Receiving Care in Three Large HIV Clinics in Nasarawa State, Nigeria

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World Journal of AIDS（艾滋病） 2024年第1期 1页

作者： Prosper Okonkwo Oluseye Ajayi Deborah babatunde Dimas Mercy ezekiel

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Lead, Zinc and Iron Pollutants Load Assessment in Selected Rivers in Southern Nigeria: Implications for Domestic Uses

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Journal of Water Resource and Protection 2024年第1期16卷 58-82页

作者： Ochuko Ushurhe Ozabor Famous ezekiel Ovuokerie Gunn Sapere-Obi Martha Ladebi Department of Environment Management and Toxicology Faculty of Environmental Sciences Dennis Osadebay University Asaba Nigeria Department of Urban and Regional Planning Niger Delta University Wilberforce Island Nigeria Department of Disaster Management School of Built Environment University of Salford Salford UK

The aim of the study is to comparatively assess the concentrations of lead, zinc and iron in Rivers Ase, Warri and Ethiope, in Nigeria. Monthly water samples were collected from six randomly selected sites along the rivers course. 72 water samples were collected from each river at 0 - 15 cm depths. Samples were analysed based on the standard methods recommended by the WHO for testing lead, zinc and iron. The assessment of the water quality was done using the Water Quality Index (WQI) of the Canadian Council of Ministers of the Environment (CCME-WQI). While hypotheses were tested using ANOVA. Findings indicated that CCME-WQI values were 47.3, 66.52 and 78.7. This meant that the water quality of River Ase is impaired and departed from desirable levels, while that of Warri and Ethiope were considered to occasionally be impaired and depart from desirable levels. The ANOVA model showed that there is a significant variation in heavy metal load in the selected rivers at P < 0.05. River water was put to domestic uses such as drinking (20.5%) preparing food (17.8%), bathing (19.8%), washing clothes and dishes (21.3%), brushing teeth (13.3%), and catering for domestic animals (7.5%). Poverty (49.5%) was the major reason for the use of river water for domestic purposes. The locals highlighted that they usually suffer from cholera (26.8%), diarrhoea (25.8%), dysentery (24%) and typhoid (23.5%) as a result of using the river water. The study recommended routine monitoring of anthropogenic and geologic activities, testing of the water regularly amongst others.

关键词： Assessment Water-Quality-Index Domestic Heavy-Metals

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N-acetylcysteine and zinc sulphate abate di-2-ethylhexyl phthalate-mediated reproductive dysfunction in rats:Focus on oxidative and sex hormone receptors mechanisms

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Asian pacific Journal of Reproduction 2024年第5期13卷 228-240页

作者： Victor Oghenekparobo Emojevwe Mega Obukohwo Oyovwi Kayode ezekiel Adewole Peggy Ejiro Ohwin Adeniran Oluwadamilare Akinola Alexander Obidike Naiho Eze Kingsley Nwangwa Victor Omo-Idonije Motunrayo Lade-Ige Benneth Ben-Azu Department of Physiology University of Medical SciencesOndo CityOndo StateNigeria Department of Physiology Delta State UniversityAbrakaDelta StateNigeria Department of Physiology Adeleke UniversityEdeOsun StateNigeria Department of Biochemistry University of Medical SciencesOndo CityOndo StateNigeria Department of Pharmacology Delta State UniversityAbrakaDelta StateNigeria

Objective:To investigate the potential of N-acetylcysteine(NAC)and zinc sulphate(ZnSO_(4))in mitigating reproductive dysfunction caused by di-2-ethylhexyl phthalate(DEHP)in rats and to understand the underlying mechanisms,specifically oxidative stress and sex hormone receptor ***:Thirty-five male Wistar rats were randomly divided into five equal groups(n=7 per group).Group 1 was administered 0.5 mL of distilled water and served as the control *** 2 was given only DEHP(750 mg/kg/day),while group 3,4 and 5 were given DEHP(750 mg/kg/day)plus NAC(100 mg/kg/day),DEHP(750 mg/kg/day)plus ZnSO_(4)(0.5 mg/kg/day),and DEHP(750 mg/kg/day)plus NAC(100 mg/kg/day)as well as ZnSO_(4)(0.5 mg/kg/day),*** treatments lasted for 21 *** were obtained after the rats were sacrificed,and hormones levels in the serum and markers of oxidative stress in the testicles were analyzed using the enzyme-linked immunosorbent *** amount of androgen receptors in the testicles was determined by immunohistochemistry,and the susceptibility of testosterone and DEHP to bind to androgen receptor and 5α-reductase was determined by molecular docking ***:DEHP decreased reproductive hormones,testicular antioxidant enzymes,increased malondialdehyde levels,and negatively impacted histology of the pituitary and *** or ZnSO_(4) treatment showed a marked improvement in testicular antioxidant status and hormone levels,as well as a positive effect on the histology of the pituitary and *** combination of both treatments appeared to be more *** affinity of DEHP to bind to androgen receptors may lead to disruption of androgen receptor signaling,which can further result in dysfunction of hormones related to ***,NAC is more likely to form stronger binding interactions with follicle stimulating hormone and luteinizing hormone receptors,as well as gonadotropin-releasing hormone receptors,when compared to ***:The pos

关键词： Di-2-ethylhexyl phthalate Testosterone Androgen receptor 5α-reductase Oestrogen Luteinizing hormone

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Nigerian antimalarial plants and their anticancer potential:A review

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Journal of Integrative Medicine 2020年第2期18卷 92-113页

作者： Kayode ezekiel Adewole Department of Biochemistry Faculty of Basic Medical SciencesUniversity of Medical SciencesOndoOndo State 234Nigeria

Cancer is a leading cause of death globally, while malaria is the leading cause of death from parasitic diseases in Nigeria. Historically, plant remedies have been used to manage both cancer and ***, the possibility of treating cancer with antimalarial remedies has long been reported, even though the two diseases appear to have little in common. However, a body of research has indicated the potential anticancer activity of both synthetic and nature-derived antimalarials. In Nigeria, over 100 plants are used for the management of malaria, but little is known for their potential role in combatting cancer. Therefore, this review is to highlight the documented anticancer activities of plants used to treat malaria in Nigeria, with the goal of supporting anticancer drug discovery. Scientific databases were used to search for antimalarial plants using selected keywords. Of over 100 plants used to treat malaria in Nigeria, 56 have documented anticancer properties, containing alkaloids, flavonoids, tannins, terpenes,terpenoids, quinones, anthraquinones, saponins, steroids, sterols, organosulfur compounds and other polyphenols as the major bioactive components. The major mechanisms of anticancer activity include induction of apoptosis and autophagy, arrest of cell growth, generation of reactive oxygen species and inhibition of angiogenesis. However, mechanistic and clinical investigations of the anticancer properties of most of these plants are still lacking. Notwithstanding, the huge anticancer potential uncovered by the in vitro or in vivo studies and a few clinical studies, Nigerian antimalarial plants may provide a valuable resource, ready to be harnessed for anticancer drug development.

关键词： Anticancer Cytotoxicity Antimalarial Medicinal plants Nigeria

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Stability Assessment of Some West African Okra （Abelmoschus caillel~ Genotypes in Nigerian Genebank

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Journal of Life Sciences 2011年第11期5卷 906-912页

作者： Aladele Sunday ezekiel Omolayo Johnson Ariyo Olusola babatunde Kehinde2 Department of Plant Genetic Resources National Centre for Genetic Resources and Biotechnology （NACGRAB） Ibadan 200273 Nigeria Department of Plant Breeding and Seed Technology University of Agriculture A beokuta 110101 Nigeria

Stability among 50 accessions of West African okra （Abelmoschus caillei） was assessed under three diverse ecological environments at Abeokuta, Ibadan and Mokwa in Nigeria during 2005 and 2006 cropping season. The accessions were grown in a Randomized Complete Block Design with three replications; data were collected on 5-10 randomly selected plants from each plot. Only 20 accessions were subjected to stability analysis on the basis of yield across the three environments. The joint regression analysis, deviation means square were computed using Eberhart and Russell method and complemented with Francis and Kannenberg method. The regression coefficients of accessions mean yields on the environmental index resulted in regression coefficients ranging in values from 0.5549 to 1.6667. OAA/96/175-5328, NGAE-96-011 and NGAE-96-0060 were among the superior genotypes with high yield performance. The large variation in regression values indicated large differences in genotype response to different environments. It suggests that stability concept of Ebelhart and Russell could be modified to use any yield components that has strong correlation with yield for stability analysis. The two promising accessions ofA. caillei （NGAE-96-011 and NGAE-96-0060） needed to be further tested on farmers＇ field to obtain on-farm data, alter which it should be recommended for official registration and released by the National Committee on Naming, Registration and Release of Crop varieties in Nigeria.

关键词： Stability assessment environmental index genotype West African okra.

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Multiaxially-stretchable kirigami-patterned mesh design for graphene sensor devices

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Nano Research 2020年第5期13卷 1406-1412页

作者： Hyo Chan Lee ezekiel YHsieh Keong Yong SungWoo Nam Department of Mechanical Science and Engineering University of Illinois at Urbana–ChampaignUrbanaIllinois 61801USA Department of Materials Science and Engineering University of Illinois at Urbana–ChampaignUrbanaIllinois 61801USA Materials Research Laboratory University of Illinois at Urbana–ChampaignUrbanaIllinois 61801USA Micro and Nanotechnology Laboratory University of Illinois at Urbana–ChampaignUrbanaIllinois 61801USA Carle Illinois College of Medicine University of Illinois at Urbana–ChampaignChampaignIllinois 61820USA

In wearable electronics,significant research has gone into imparting stretchability and flexibility to otherwise rigid electronic components while maintaining their electrical *** far,this has been achieved through various geometric modifications of the rigid conductive components themselves,such as with microcracked,buckled,or planar meander ***,strategic placement of these resulting components within the overall devices,such as embedding them at the neutral plane,has been found to further enhance mechanical stability under ***,these strategies are still limited in performance,failing to achieve fully strain-insensitive electrical performance under biaxial stretching,twisting,and mixed strain ***,we developed a new platform for wearable,motion artifact-free sensors using a graphene-based multiaxially stretchable kirigami-patterned mesh *** normalized resistance change of the electrodes and graphene embedded in the structure is smaller than 0.5%and 0.23%under 180°torsion and 100%biaxial strain,***,the resistance change is limited to 5%under repeated stretching-releasing cycles from 0%to 100%biaxial *** addition,we investigated the deformation mechanisms of the structure with finite element *** on the simulation results,we derived a dimensionless geometric parameter that enables prediction of stretchability of the structure with high ***,as a proof-of-concept,we demonstrated a biaxially-stretchable graphene-based sensor array capable of monitoring of temperature and glucose level with minimized motion-artifacts.

关键词： kirigami mesh strain-insensitive wearable graphene glucose

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Lead, Zinc and Iron Pollutants Load Assessment in Selected Rivers in Southern Nigeria: Implications for Domestic Uses

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Journal of Water Resource and Protection（水资源与保护） 2024年第1期

作者： Ochuko Ushurhe Ozabor Famous ezekiel Ovuokerie Gunn Sapere-Obi Martha Ladebi

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