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Acute effects of physical exercise in type 2 diabetes: A review

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World Journal of Diabetes 2014年第5期5卷 659-665页

作者： Ricardo Yukio Asano Marcelo Magalhes Sales Rodrigo Alberto Vieira Browne José fernando Vila Nova Moraes Hélio José Coelho Júnior Milton Rocha Moraes Hebert Gustavo Simoes Universidade Mogi das Cruzes Center of Health Sciences Mogi das Cruzes 08770-490 Brazil Universidade Católica de Brasília School of Physical Education Brasília 72030-170 Brazil UDF-Centro Universitário School Health Brasilia 70390-045 Brazil Universidade Federal do Rio Grande do Norte Center of Health Sciences Natal 59078-970 Brazil Universidade Federal do Vale do So Francisco School of Physical Education Petrolina 56304205 Brazil Universidade Estadual de Campinas School of Physical Education Campinas 130883-851Brazil

The literature has shown the efficiency of exercise in the control of type 2 diabetes(T2D), being suggested as one of the best kinds of non-pharmacological treatments for its population. Thus, the scientific production related to this phenomenon has growing exponentially. However, despite its advances, still there is a lack of studies that have carried out a review on the acute effects of physical exercise on metabolic and hemodynamic markers and possible control mechanisms of these indicators in individuals with T2 D, not to mention that in a related way, these themes have been very little studied today. Therefore, the aim of this study was to organize and analyze the current scientific production about the acute effects of physical exercise on metabolic and hemodynamic markers and possible control mechanisms of these indicators in T2 D individuals. For such, a research with the following keywords was performed:-exercise; diabetes and post-exercise hypotension; diabetes and excess post-exercise oxygen consumption; diabetes and acute effects in PUBMED, SCIELO and HIGHWIRE databases. From the analyzed studies, it is possible to conclude that, a single exercise session can promote an increase in the bioavailability of nitric oxide and elicit decreases in postexercise blood pressure. Furthermore, the metabolic stress from physical exercise can increase the oxidation of carbohydrate during the exercise and keep it, in high levels, the post exercise consumption of O2, this phenomenon increases the rate of fat oxidation during recovery periods after exercise, improves glucose tolerance and insulin sensitivity and reduces glycemia between 2-72 h, which seems to be dependent on the exercise intensity and duration of the effort.

关键词： Metabolic diseases Hypertension Nitric oxide Blood glucose Oxygen consumption

Dendritic cell vaccination in glioblastoma after fluorescenceguided resection

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World Journal of Clinical Oncology 2012年第11期3卷 142-149页

作者： Ricardo Diez Valle Ascension Lopez-Diaz de Cerio Susana Inoges Sonia Tejada fernando Pastor Helena Villanueva Jaime Gallego Jaime Espinos Javier Aristu Miguel Angel Idoate Enrique Andreu Maurizio Bendandi Department of Neurosurgery University of Navarra Hospital 31008 Pamplona Navarra Spain Lab of Immunotherapy CIMA 31008 Pamplona Navarra Spain Immunotherapy Program University of Navarra Hospital 31008 Pamplona Navarra Spain Department of Neurology University of Navarra Hospital 31008 Pamplona Navarra Spain Department of Oncology University of Navarra Hospital 31008 Pamplona Navarra Spain Department of Pathology University of Navarra Hospital 31008 Pamplona Navarra Spain Cell Therapy Area University of Navarra Hospital 31008 Pamplona Navarra Spain

AIM: To assess whether the addition of a customized, active immunotherapy to standard of care including fluorescence-guided surgery, may provide hints of an improved survival for patients with poor-prognosis, incurable glioblastoma multiform. METHODS: Preliminary to our ongoing, phase-Ⅱ clinical trial, we conducted a small pilot study enrolling five consecutive patients with resectable glioblastoma. In terms of Recursive Partitioning Analysis, four patientswere class Ⅴ and one was class Ⅳ. In all five cases, fluorescence-guided surgery was employed, followed by rapid steroid discontinuation. Patients were then treated with a combination of standard radio-chemotherapy with temozolomide and tumor lysate-pulsed, mature dendritic cell-based ***: Though all five patients ultimately progressed, with any further treatment left to the sole decision of the treating oncologist, active immunotherapy was very well tolerated and induced specific immune responses in all three patients for whom enough material was available for such an assessment. Median progression-free survival was 16.1 mo. Even more important, median and mean overall survival were 27 mo and 26 mo, respectively. Three patients have died with an overall survival of 9 mo, 27 mo and 27.4 mo, while the other two are still alive at 32 mo and 36 mo, the former receiving treatment with bevacizumab, while the latter has now been off therapy for 12 mo. Four of five patients were alive at two ***: Active immunotherapy with tumor lysate-pulsed, autologous dendritic cells is feasible, safe, well tolerated and biologically efficacious. A phase-Ⅱ study is ongoing to possibly improve further on our very encouraging clinical results.

关键词： Immunotherapy Glioblastoma Fluorescence-guided surgery Dendritic cells Tumor-lysate

海绵窦血管瘤和海绵状血管畸形是不同的病变吗？

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中国现代神经疾病杂志 2007年第1期7卷 48-51页

作者： L. Femando Gonzalez Gregory P. Lekovic Jennifer Eschbacher 刘暌（译）只达石（校） Divisions of Neurological Surgery and Neuropathology BarrowNeurological Institute St. Joseph＇s Hospital and Medical CenterPhoenix Arizona 天津市环湖医院神经外科 300060 天津医科大学总医院

海绵状血管畸形是发生在中枢神经系统内具有显著特征的病变，尽管其与海绵窦血管瘤在组织学方面的特征相似，但是表现各异（表1）。由于两种病变的自然病程和治疗手段不同，所以命名应该适当规范。本文对以往文献进行简要回顾。

关键词：海绵状血管畸形血管瘤海绵窦病变中枢神经系统自然病程组织学

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多跨GFRP混凝土组合梁的弯曲性能

钢结构(中英文) 2009年第8期 89-89页

作者： Joo R.Correia fernando A.Branco Joo G.Ferreira

给出多跨GFRP混凝土混合梁弯曲性能的试验和分析结果。以往的研究揭示了简支梁结构中GFRP混凝土组合截面从GFRP外形到混凝土单元的特征和技术优势。当前研究的目标是连续结构GFRP混凝土混合截面的弯曲性能,与Isostatic系统相比,该结构... 详细信息

给出多跨GFRP混凝土混合梁弯曲性能的试验和分析结果。以往的研究揭示了简支梁结构中GFRP混凝土组合截面从GFRP外形到混凝土单元的特征和技术优势。当前研究的目标是连续结构GFRP混凝土混合截面的弯曲性能,与Isostatic系统相比,该结构除了有较小的变形外,横截面和结构的超静定性也允许结构破坏时,有一定的假性延展。为此,建立一系列设计方程用于分析连续组合梁受到正负弯矩时的弯曲性能。采用这些方程对2个带有粘结剪切连接系统的2跨和3跨连续组合梁进行设计。通过弯曲试验,对多跨GFRP混凝土组合梁的正常使用性能和破坏机制进行研究。

关键词：纤维增强复合材料玻璃纤维增强塑料玻璃纤维增强复合材料GFRP塑模成型混凝土剪切连接组合梁组合结构

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不再孤寂

新建筑 2015年第6期 35-38页

作者：菲奥娜多.拉纳路易斯.E.卡拉赞万龙雨美国德克萨斯州大学奥斯汀分校建筑学院美国罗杰威廉姆斯大学建筑学院华中科技大学建筑与城市规划学院

现代的拉丁美洲建筑史就像是一个不断积累融合的过程史,大量的学术会议和讨论正在开始慢慢改变这一被历史铸造的格局。与经济一体化同时发生的现象,是地域性现代文化遗产的价值提升。在21世纪头10年所出现的几个最具精彩建筑案例都与当... 详细信息

现代的拉丁美洲建筑史就像是一个不断积累融合的过程史,大量的学术会议和讨论正在开始慢慢改变这一被历史铸造的格局。与经济一体化同时发生的现象,是地域性现代文化遗产的价值提升。在21世纪头10年所出现的几个最具精彩建筑案例都与当地的建筑文化息息相关,这些案例不仅遵从当地所流行的现代主义,也巧妙地融入些许异域风情。

关键词：拉丁美洲建筑历史建筑文化

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Jardim Edite社会性住宅综合体

新建筑 2015年第6期 90-90页

作者： Marta Moreira Milton Braga fernando de Mello Franco Eduardo Ferroni Pablo Hereú 王玺 MMBB建筑师事务所 H+F建筑师事务所华中科技大学建筑与城市规划学院

Jardim Edite社会性住宅综合体项目是受托安置圣保罗城市内一个近来显著发展的商业金融区内的贫民。为了确保能整合该住宅综合体和富裕的周边环境,该项目将住宅功能竖向地安排在建筑上层,而地面部分完全用于公共设施。公共设施既可供居... 详细信息

Jardim Edite社会性住宅综合体项目是受托安置圣保罗城市内一个近来显著发展的商业金融区内的贫民。为了确保能整合该住宅综合体和富裕的周边环境,该项目将住宅功能竖向地安排在建筑上层,而地面部分完全用于公共设施。公共设施既可供居住社区使用也可服务于周边的城市群体,给该区域的经济活动和日常生活提供了综合设施。

关键词：住宅功能综合体社会性公共设施周边环境居住社区经济活动城市

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Corrigendum to‘Application of bioactive hydrogels combined with dental pulp stem cells for the repair of large gap peripheral nerve injuries’[Bioactive Mater.6(3)(2021)638-654]

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Bioactive Materials 2022年第1期7卷 2-2页

作者： Lihua Luo Yan He Ling Jin Yanni Zhang fernando P.Guastaldi Abdullkhaleg A.Albashari Fengting Hu Xiaoyan Wang Lei Wang Jian Xiao Lingli Li Jianming Wang Akon Higuchi Qingsong Ye School and Hospital of Stomatology Wenzhou Medical UniversityWenzhouZhejiangChina Tianyou Hospital Wuhan University of Science and TechnologyWuhan430064China Skeletal Biology Research Center Massachusetts General HospitalHarvard School of Dental MedicineBostonMA02114USA Wenzhou Institute of Biomaterials and Engineering WenzhouZhejiang Province325000China Molecular Pharmacology Research Center School of PharmacyWenzhou Medical UniversityWenzhou325035China School of Ophthalmology and Optometry Eye HospitalWenzhou Medical UniversityWenzhouZhejiang325027China Department of Biliary and Pancreatic Surgery Cancer Research CenterAffiliated Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Center of Regenerative Medicine Renmin Hospital of Wuhan UniversityWuhan430060China

The authors regret that the author(A.H.)was removed as an agreement could not be reached between the two affiliations of the *** authors would like to apologise for any inconvenience caused.

关键词： injuries removed repair

用一种纳米技术途径引介环境可持续发展的化学主题:通过腐植酸改性的超顺磁纳米粒子去除有害金属离子

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腐植酸 2017年第3期 66-66页

作者： Delmarcio Gomes da Silva fernando Menegatti de Melo Alceu Totti Silveira 韩立新中国腐植酸工业协会

实验室实验说明应关注用腐植酸功能化的超顺磁纳米粒子对污水进行处理。实验由一群高中生进行,内容包括纳米粒子的合成和微观表征,与水中典型的金属离子污染物的相互作用。为帮助学生理解实验,使用竞争性试剂,例如氨来恢复和回收利用纳... 详细信息

实验室实验说明应关注用腐植酸功能化的超顺磁纳米粒子对污水进行处理。实验由一群高中生进行,内容包括纳米粒子的合成和微观表征,与水中典型的金属离子污染物的相互作用。为帮助学生理解实验,使用竞争性试剂,例如氨来恢复和回收利用纳米粒子,让学生们对配位化学概念进行探讨,凸显腐植酸对金属离子的亲和力。

关键词：纳米粒子金属离子超顺磁腐植酸

Robotic versus laparoscopic liver resection for huge (≥10 cm) liver tumors: an international multicenter propensity-score matched cohort study of 799 cases

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Hepatobiliary Surgery and Nutrition 2023年第2期12卷 205-215,I0005页

作者： Tan-To Cheung Rong Liu Federica Cipriani Xiaoying Wang Mikhail Efanov David Fuks Gi-Hong Choi Nicholas L.Syn Charing C.N.Chong Fabrizio Di Benedetto Ricardo Robles-Campos Vincenzo Mazzaferro fernando Rotellar Santiago Lopez-Ben James O.Park Alejandro Mejia Iswanto Sucandy Adrian K.H.Chiow Marco V.Marino Mikel Gastaca Jae Hoon Lee TPeter Kingham Mathieu D’Hondt Sung Hoon Choi Robert P.Sutcliffe Ho-Seong Han Chung-Ngai Tang Johann Pratschke Roberto I.Troisi Go Wakabayashi Daniel Cherqui Felice Giuliante Davit L.Aghayan Bjorn Edwin Olivier Scatton Atsushi Sugioka Tran Cong Duy Long Constantino Fondevila Mohammad Abu Hilal Andrea Ruzzenente Alessandro Ferrero Paulo Herman Kuo-Hsin Chen Luca Aldrighetti Brian K.P.Goh International robotic and laparoscopic liver resection study group investigators Department of Surgery Queen Mary HospitalThe University of Hong KongHong Kong SARChina Faculty of Hepatopancreatobiliary Surgery The First Medical Center of Chinese People’s Liberation Army(PLA)General HospitalBeijingChina Hepatobiliary Surgery Division IRCCS San Raffaele HospitalMilanItaly Department of Liver Surgery and Transplantation Liver Cancer InstituteZhongshan HospitalFudan UniversityShanghaiChina Department of Hepato-Pancreato-Biliary Surgery Moscow Clinical Scientific CenterMoscowRussia Department of Digestive Oncologic and Metabolic SurgeryInstitute Mutualiste MontsourisUniversite Paris DescartesParisFrance Division of Hepatopancreatobiliary Surgery Department of SurgerySeverance HospitalYonsei University College of MedicineSeoulKorea Department of Hepatopancreatobiliary and Transplant Surgery Singapore General Hospital and Yong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore Division of Hepatobiliary and Pancreatic Surgery Department of SurgeryPrince of Wales HospitalThe Chinese University of Hong KongHong Kong SARChina HPB Surgery and Liver Transplant Unit University of Modena and Reggio EmiliaModenaItaly Department of General Visceral and Transplantation SurgeryClinic and University Hospital Virgen de la ArrixacaIMIB-ARRIXACAMurciaSpain HPB Surgery Hepatology and Liver TransplantationFondazione IRCCS Istituto Nazionale Tumori di MilanoMilanItaly HPB and Liver Transplant Unit Department of General SurgeryClinica Universidad de NavarraUniversidad de NavarraPamplonaSpain Institute of Health Research of Navarra(IdisNA) PamplonaSpain Hepatobiliary and Pancreatic Surgery Unit Department of SurgeryDr.Josep Trueta HospitalIdIBGiGironaSpain Hepatobiliary Surgical Oncology Department of SurgeryUniversity of Washington Medical CenterSeattleWAUSA The Liver Institute Methodist Dallas Medical CenterDallasTXUSA AdventHealth Tampa Digestive Health InstituteTampaFLUSA Hepatopancreatobiliary Unit Department of SurgeryChangi General

Background:The use of laparoscopic(LLR)and robotic liver resections(RLR)has been safely performed in many institutions for liver tumours.A large scale international multicenter study would provide stronger evidence and insight into application of these techniques for huge liver tumours≥10 ***:This was a retrospective review of 971 patients who underwent LLR and RLR for huge(≥10 cm)tumors at 42 international centers between ***:One hundred RLR and 699 LLR which met study criteria were *** comparison between the 2 approaches for patients with huge tumors were performed using 1:3 propensity-score matching(PSM)(73 vs.219).Before PSM,LLR was associated with significantly increased frequency of previous abdominal surgery,malignant pathology,liver cirrhosis and increased median *** PSM,RLR and LLR was associated with no significant difference in key perioperative outcomes including media operation time(242 vs.290 min,P=0.286),transfusion rate rate(19.2%vs.16.9%,P=0.652),median blood loss(200 vs.300 mL,P=0.694),open conversion rate(8.2%vs.11.0%,P=0.519),morbidity(28.8%vs.21.9%,P=0.221),major morbidity(4.1%vs.9.6%,P=0.152),mortality and postoperative length of stay(6 vs.6 days,P=0.435).Conclusions:RLR and LLR can be performed safely for selected patients with huge liver tumours with excellent *** was no significant difference in perioperative outcomes after RLR or LLR.

关键词： Laparoscopic liver resection(LLR) robotic liver resection(RLR) hepatocellular carcinoma colorectal liver metastases huge