检索结果-南通市图书馆

Application of wastewater-based epidemiological monitoring of COVID-19 for disease surveillance in the city

Frontiers of Environmental Science & Engineering 2024年第8期18卷 81-87页

作者： Heng Chen Zhenhua Chen Liwen Hu fengzhu tang Dan Kuang Jiayi Han Yao Wang Xiao Zhang Yue Cheng Jiantong Meng Rong Lu Lan Zhang Chengdu Workstation for Emerging Infectious Disease Control and Prevention Chinese Academy of Medical SciencesChengdu 610047China Chengdu Center for Disease Control and Prevention Chengdu 610047China National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases Beijing 100050China National Institute of Environmental Health Chinese Center for Disease Control and PreventionBeijing 100050China

Wastewater-based surveillance serves as a supplementary approach to clinical surveillance of COVID-19 during the *** study aimed to track the prevalence of the disease and the viral genetic variability through wastewater-based surveillance in the post-epidemic *** January to December 2023,samples were collected from the influent lines of two wastewater treatment plants(WWTPs),concentrated using PEG8000,and subjected to detection of the target genes ORF 1ab and N of SARS-CoV-2 via reverse transcriptional quantitative PCR(RT-qPCR).For next-generation sequencing(NGS),high-quality samples from both wastewater and clinical patients were *** analysis were performed using R software to evaluate the correlation between the SARSCoV-2 RNA concentrations in wastewater and positive rate of reported cases,indicating a positive *** diversity patterns of SARS-CoV-2 in wastewater resembled those in the patient source based on Principal Coordinates Analysis(PCoA)with three clusters for different *** rise of RNA concentration in wastewater indicates the growth of cases and the emergence of new variants,serving as an early warning of potential viral mutations,disease outbreaks even possible ***,the genomic surveillance of wastewater could help identify new variants that may not be captured through population monitoring,especially when sample sizes are ***,surveillance of SARS-CoV-2 in municipal wastewater has emerged as a reliable,earlywarning monitoring system for COVID-19 in the post-epidemic era.

关键词： Wastewater-based epidemiology Monitoring COVID-19 Post-epidemic era

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

An aggregate flow based scheduler in multi-task cooperated UAVs network

引用

Chinese Journal of Aeronautics 2020年第11期33卷 2989-2998页

作者： Xiaohuan LI Ziqi XIE Jin YE Xin tang Chunhai LI fengzhu tang Rong YU School of Information and Communication Guilin University of Electronic TechnologyGuilin 541004China Guangxi Key Laboratory of Multimedia Communications and Network Technology School of ComputerElectronics and InformationGuangxi UniversityNanning 530004China National Engineering Laboratory for Comprehensive Transportation Big Data Application Technology(Guangxi) Nanning 530001China School of Automation Guangdong University of TechnologyGuangzhou 510006China

Unmanned Aerial Vehicles(UAVs)cooperative multi-task system has become the research focus in recent ***,the existing network frameworks of UAVs are not flexible and efficient enough to deal with the complex multi-task scheduling,because they are not able to perceive the different *** this paper,a novel cooperated UAVs network framework for multi-task scheduling is *** is a three-layer network including a core layer,an aggregation layer and an execution layer,which enhances the efficiency of multi-task distribution,aggregation and ***,an Aggre Gate Flow(AGFlow)based scheduler is dedicatedly designed to maximize the task completion rate,whose key point is to aggregate flows belonging to one task during the multi-task transmission of UAVs network and to allocate priority by calculating the urgency-level of each *** results demonstrate that,compared with that of state-of-the-art scheduler,the average task completion rate of AGFlow based scheduler is raised by 0.278.

关键词： Mixed-flow scheduling Multi-task Task completion rate Unmanned Aerial Vehicles(UAVs) Urgency-level

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

异常纺锤体样小头畸形相关蛋白在鼻咽癌中的表达及其临床意义

引用

山东大学耳鼻喉眼学报 2024年第3期38卷 18-25页

作者：杨开炎唐凤珠覃启才李旭祥冯大益农丰靖杨秋云百色市人民医院耳鼻咽喉头颈外科广西壮族自治区人民医院耳鼻咽喉头颈外科百色市人民医院病理科

目的通过免疫组化染色的方法研究异常纺锤体样小头畸形相关蛋白(abnormal spindle-like microcephaly associated protein, ASPM)在鼻咽癌组织样本中的表达情况，进一步分析ASPM蛋白表达与鼻咽癌患者临床病理参数和预后的关系，探讨ASP... 详细信息

目的通过免疫组化染色的方法研究异常纺锤体样小头畸形相关蛋白(abnormal spindle-like microcephaly associated protein, ASPM)在鼻咽癌组织样本中的表达情况，进一步分析ASPM蛋白表达与鼻咽癌患者临床病理参数和预后的关系，探讨ASPM mRNA在鼻咽癌中的表达情况。方法从GEO数据库下载鼻咽癌的芯片数据集，使用R语言对鼻咽癌芯片数据集进行差异表达分析；使用免疫组化染色方法分析ASPM蛋白在鼻咽癌中的差异表达；使用卡方检验的方法分析ASPM表达与鼻咽癌患者临床病理参数的相关性；采用生存曲线分析ASPM表达与鼻咽癌患者预后的关系；采用Cox回归模型分析影响鼻咽癌患者预后的危险因素；使用受试者工作特征(receiver operator characteristic, ROC)曲线评估各种预后参数预测鼻咽癌患者预后的效能。结果通过鼻咽癌芯片数据分析发现ASPM mRNA在鼻咽癌芯片数据集中高表达(P<0.001);免疫组化染色结果显示鼻咽癌组织中ASPM蛋白表达明显高于鼻咽炎组织(P<0.001),ASPM表达与T分期(P=0.048)、N分期(P=0.050)及总临床分期(P=0.029)相关，高表达ASPM蛋白组患者总生存期短于低表达ASPM蛋白组患者(P<0.001);通过多因素Cox回归模型分析，显示ASPM表达水平可能为影响鼻咽癌患者预后的独立危险因素(P=0.015);通过ROC曲线分析，显示联合总临床分期及ASPM表达用于预测鼻咽癌患者预后具有更高的准确性(P<0.001)。结论 ASPM在鼻咽癌组织样本中高表达，其高表达与鼻咽癌的恶性程度、疾病进展及较差的预后相关，可能成为鼻咽癌中有价值的预测预后的生物标志物。联合总临床分期及ASPM表达用于预测鼻咽癌患者预后可能是一种有前景的方法。

关键词：鼻咽癌免疫组化肿瘤预后异常纺锤体样小头畸形相关蛋白差异表达

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

ZBTB7A governs 2-DG-inhibited glycolysis by regulating GLUT1 in nasopharyngeal carcinoma

引用

BIOCELL 2022年第12期46卷 2659-2669页

作者： FEI LIU JIAZHANG WEI JIAO LAN YONGLI WANG JIANXIANG YE CHENG SU MINGZHENG MO fengzhu tang BING LI MIN LI WEIMING DENG LINSONG YE WENLIN HUANG JINGJIN WENG WEI JIAO SHENHONG QU Research Center of Medical Sciences The People’s Hospital of Guangxi Zhuang Autonomous RegionGuangxi Academy of Medical SciencesNanning530021China Department of Otolaryngology&Head and Neck The People’s Hospital of Guangxi Autonomous RegionGuangxi Academy of Medical SciencesNanning530021China Department of Medical Oncology Guangxi Medical University Cancer HospitalNanning530021China

Our previous studies suggested a potential interaction between the POK erythroid myeloid ontogenic factor ZBTB7A and glucose transporter 1(GLUT1)in nasopharyngeal carcinoma(NPC).This study was designed to confirm the interaction and further evaluate the precise mechanism by which ZBTB7A and GLUT1 regulate NPC *** binding sites between ZBTB7A and the promoter of GLUT1 were predicted by *** expression was measured by quantitative real-time polymerase chain reaction(qPCR),western blotting,and *** activities of key glycolysis enzymes,including hexokinase(HK),pyruvate kinase(PK),lactate dehydrogenase(LDH),and lactate,were detected using specific enzyme-linked immunosorbent assay *** connection between ZBTB7A and GLUT1 was analyzed by dual-luciferase reporter assay and chromatin *** vitality,proliferation,and tumorigenicity of the cells expressing different levels of ZBTB7A were tested by adding the glycolysis inhibitor 2-deoxy-D-glucose(2-DG),followed by MTT,colorimetric focus forming,and xenograft assays,*** results showed that high expression of GLUT1 was associated with late-stage *** constructing stably transfected cells with lentiviruses,ZBTB7A was effectively knocked down in 5-8F cells(RNAi-5-8F)and overexpressed in 6-10B cells(ZBTB7A-6-10B).The up-or downregulation of GLUT1 secondary to ZBTB7A changes was also *** vitality and proliferation of the cells expressing low ZBTB7A were notably blocked by *** cells expressing high ZBTB7A were not very sensitive to *** growth of RNAi-5-8F xenografts was strongly suppressed by *** activities of HK,PK,and LDH were suppressed by 2-DG in the cells expressing low ***-5-8F cells had the lowest 2-DG-induced lactate ***7A directly suppressed the promoter region of GLUT1 to regulate GLUT1 ***,ZBTB7A controls the 2-DG-induced inhibition of glycolysis by affecting GLUT1.

关键词： Nasopharyngeal carcinoma ZBTB7A GLUT1 Glycolysis 2-DG

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

前庭辅助系统现状及新进展

引用

临床耳鼻咽喉头颈外科杂志 2020年第3期34卷 285-288页

作者：王涛唐凤珠袁弘广西壮族自治区人民医院耳鼻咽喉头颈外科南宁530021

前庭功能障碍会严重影响日常生活及工作。近年来除了半规管填塞术、前庭康复以及梅尼埃病鼓室内注射等治疗手段不断完善并发展外,其他前庭疾病治疗方法进展不大。目前对于难治性眩晕疾病(如常规治疗无效的梅尼埃病),破坏性的治疗(如鼓... 详细信息

前庭功能障碍会严重影响日常生活及工作。近年来除了半规管填塞术、前庭康复以及梅尼埃病鼓室内注射等治疗手段不断完善并发展外,其他前庭疾病治疗方法进展不大。目前对于难治性眩晕疾病(如常规治疗无效的梅尼埃病),破坏性的治疗(如鼓室内庆大霉素注射、迷路切除和前庭神经部分切除)仍然是最佳选择。随着对前庭疾病认识的逐渐深入,目前正在探索通过前庭辅助系统改善患者的前庭功能。前庭辅助系统主要集中在2个领域:穿戴式前庭辅助装置和人工前庭装置。

关键词：前庭疾病外置前庭假体前庭植入

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

高职院校图书馆专业学科服务探索

引用

科技情报开发与经济 2013年第11期23卷 68-70页

作者：唐凤珠广西机电职业技术学院图书馆广西南宁530007

从专业用户研究、深入发掘文献价值的研究、形式多样的专业学科服务推广手段及提高学科馆员的素质4个方面论述了高职院校图书馆专业学科服务。

关键词：高职院校图书馆专业学科服务专业用户文献价值学科馆员

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Harboring CAR-T cells using an injectable scaffold to treat solid tumors

引用

National Science Review 2024年第5期11卷 91-92页

作者： Li tang Institute of Bioengineering (IBI) école polytechnique fédérale de Lausanne (EPFL)

Genetic expression of chimeric antigen receptors (CAR) enables T cells to target and kill cancer cells in an MHCindependent manner, resulting in a potent antitumor response [1]. To date, more than 10 CAR-T cell products have been approved globally for the treatment of hematologic disorders such as relapsed/refractory B-cell acute lymphoblastic leukemia, non-Hodgkin lymphoma, and multiple myeloma [2,3].

关键词： IMMUNOTHERAPY CANCER

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Topologically protected entanglement switching around exceptional points

引用

Light(Science & Applications) 2024年第8期13卷 1631-1644页

作者： Zan tang Tian Chen Xing tang Xiangdong Zhang Key Laboratory of Advanced Optoelectronic Quantum Architecture and Measurements of Ministry of Education Beijing Key Laboratory of Nanophotonics&Ultrafine Optoelectronic SystemsSchool of PhysicsBeijing Institute of Technology100081 BeijingChina

The robust operation of quantum entanglement states is crucial for applications in quantum information,computing,and communications^(1–3).However,it has always been a great challenge to complete such a task because of decoherence and ***,we propose theoretically and demonstrate experimentally an effective scheme to realize robust operation of quantum entanglement states by designing quadruple degeneracy exceptional *** encircling the exceptional points on two overlapping Riemann energy surfaces,we have realized a chiral switch for entangled states with high *** to the topological protection conferred by the Riemann surface structure,this switching of chirality exhibits strong robustness against perturbations in the encircling ***,we have experimentally validated such a scheme on a quantum walk *** work opens up a new way for the application of non-Hermitian physics in the field of quantum information.

关键词： exceptional quantum Riemann

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

An economic way to achieve all-weather CO2 reduction

引用

National Science Review 2024年第3期11卷 46-47页

作者： Junwang tang Department of Chemical Engineering University College London

Utilising solar power to convert carbon dioxide（CO2） into hydrocarbon fuels presents an eco-friendly method to address dependence on fossil fuels and contribute to a net-zero CO2emission goal[1,2].

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

UAV-assisted data collection for wireless sensor networks with dynamic working modes

引用

Digital Communications and Networks 2024年第3期10卷 805-812页

作者： Jie Chen Jianhua tang Shien-Ming Wu School of Intelligent Engineering South China University of TechnologyGuangzhou511442China

Wireless Sensor Network(WSN)is a cornerstone of Internet of Things(IoT)and has rich application *** this work,we consider a heterogeneous WSN whose sensor nodes have a diversity in their Residual Energy(RE).In this work,to protect the sensor nodes with low RE,we investigate dynamic working modes for sensor nodes which are determined by their RE and an introduced energy ***,we employ an Unmanned Aerial Vehicle(UAV)to collect the stored data from the heterogeneous *** aim to jointly optimize the cluster head selection,energy threshold and sensor nodes’working mode to minimize the weighted sum of energy con-sumption from the WSN and UAV,subject to the data collection rate *** this end,we propose an efficient search method to search for an optimal energy threshold,and develop a penalty-based successive convex approximation algorithm to select the cluster *** we present a low-complexity iterative approach to solve the joint optimization problem and discuss the implementation *** results justify that our proposed approach is able to reduce the energy consumption of the sensor nodes with low RE significantly and also saves energy for the whole WSN.

关键词： Unmanned aerial vehicle Wireless sensor networks Cluster heads Dynamic working modes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：