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Optimization of operation conditions for extracting lithium ions from calcium chloride-type oil field brine

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International Journal of Minerals,Metallurgy and Materials 2012年第4期19卷 290-294页

作者： Hong-jun Yang qing-hai Li Bing Li feng-qin guo qing-fen Meng Wu Li qinghai Institute of Salt Lakes Chinese Academy of Sciences Xining 810008 China Graduate University of the Chinese Academy of Sciences Beijing 100049 China Fundamental Department Qinghai University Xining 81 O016 China

AI（OH）3 was prepared to extract lithium ions from calcium chloride-type oil field brine. The influences of four factors, namely temperature, Al3＋/Li＋ molar ratio, OH-/Al3＋ molar ratio, and contact time between AI（OH）3 and the brine, on the yield of lithium ions were investigated. It is found that their optimal values are 35℃, 4.5, 2.6, and 6 h, respectively. In the course of the experiment, the apparent pH value was observed. The results reveal that the apparent pH value has no remarkable influence on the yield of lithium ions. Meanwhile, the effects of the concentrations of calcium ions and magnesium ions in the brine on lithium recovery were studied. The results indicate that cal- cium ions have minor negative influence on the yield of lithium ions under optimal conditions, and magnesium ions slightly influence the yield of lithium ions.

关键词： lithium extraction oil field brine aluminium hydroxide

Synthesis of Mg_2B_2O_5 whiskers via coprecipitation and sintering process

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International Journal of Minerals,Metallurgy and Materials 2012年第10期19卷 969-972页

作者： Dong-hai Zhu Xue-ying Nai Cheng-cai Zhu feng-qin guo Shao-ju Bian Wu Li qinghai Institute of Salt Lakes Chinese Academy of Sciences Xining 810008 China Graduate University of Chinese Academy of Sciences Beijing 100049 China Department o f Basin Education Qinghai University Xining 810016 China

Mg2B2O5 whiskers with high aspect ratio were synthesized by coprecipitation and sintering process using MgCl2-6H2O, H3BO3, and NaOH as raw materials and KCl as a flux. Their formation process was investigated by thermogravimetry and differential scanning calo- rimetry （TG-DSC）, X-ray diffraction （XRD）, and scanning electron microcopy （SEM）. It is found that the products synthesized at 832℃ are monoclinic Mg2B205 whiskers with a diameter of 200-400 nm and a length of 50-80 μm. Transmission electron microscopy （TEM） and selected area electron diffraction （SAED） analyses show that the whiskers obtained at 832℃ are single crystalline and grow along with the [010] direction. The growth mechanism of Mg2B2O5 whiskers was also presented.

关键词： magnesium borate coprecipitation sintering crystal whiskers crystal growth microstructure

Induced neural stem cells regulate microglial activation through Akt-mediated upregulation of CXCR4 and Crry in a mouse model of closed head injury

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Neural Regeneration Research 2025年第5期20卷 1416-1430页

作者： Mou Gao qin Dong Dan Zou Zhijun Yang Lili guo Ruxiang Xu Department of Neurosurgery Sichuan Academy of Medical Sciences and Sichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Department of Neurosurgery Chinese PLA General HospitalBeijingChina Department of Neurology Fu Xing HospitalCapital Medical UniversityBeijingChina

Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and *** previously reported that induced neural stem cells can modulate the behavior of activated microglia via CXCL12/CXCR4 signaling,influencing their activation such that they can promote neurological ***,the mechanism of CXCR4 upregulation in induced neural stem cells remains *** this study,we found that nuclear factor-κB activation induced by closed head injury mouse serum in microglia promoted CXCL12 and tumor necrosis factor-αexpression but suppressed insulin-like growth factor-1 ***,recombinant complement receptor 2-conjugated Crry(CR2-Crry)reduced the effects of closed head injury mouse serum-induced nuclear factor-κB activation in microglia and the levels of activated microglia,CXCL12,and tumor necrosis factor-α.Additionally,we observed that,in response to stimulation(including stimulation by CXCL12 secreted by activated microglia),CXCR4 and Crry levels can be upregulated in induced neural stem cells via the interplay among CXCL12/CXCR4,Crry,and Akt signaling to modulate microglial *** agreement with these in vitro experimental results,we found that Akt activation enhanced the immunoregulatory effects of induced neural stem cell grafts on microglial activation,leading to the promotion of neurological recovery via insulin-like growth factor-1 secretion and the neuroprotective effects of induced neural stem cell grafts through CXCR4 and Crry upregulation in the injured cortices of closed head injury ***,these beneficial effects of Akt activation in induced neural stem cells were positively correlated with the therapeutic effects of induced neural stem cells on neuronal injury,cerebral edema,and neurological disorders post–closed head *** conclusion,our findings reveal that Akt activation may enhance the immunoregulatory effects of induced neura

关键词： Akt signaling cerebral edema closed head injury Crry CXCR4 induced neural stem cell microglia neuroinflammation

Sky location of massive black hole binaries in the foreground of Galactic white dwarf binaries

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 97-108页

作者： Pan guo Hong-Bo Jin Cong-feng Qiao Yue-Liang Wu The International Centre for Theoretical Physics Asia-Pacific University of Chinese Academy of Sciences The School of Physical Sciences University of Chinese Academy of Sciences Institute for Frontiers in Astronomy and Astrophysics Beijing Normal University National Astronomical Observatories Chinese Academy of Sciences Institute of Theoretical Physics Chinese Academy of Sciences

For space-based gravitational wave （GW） detection,the main noise source for massive black hole binaries （MBHBs） is attributed to approximately 10～7double white dwarf binaries in the *** a GW source,the amplitude of the detector response,recorded by a space-based gravitational wave detector,exhibits a modulation effect with a year period when observing the source from various orbital *** the adverse conditions mentioned above,where there is a strong foreground noise and annual modulation in the signals,we employed the wavelet transform and the strong-amplitude relevant orbital position search methods,which allows the weak MBHB sources to achieve higher locating *** detail,for two MBHB sources of lower intensity,the precision of luminosity distance,represented by the ratio ?DL/DLat the 95%confidence level,is enhanced by factors of ～*** angular resolutions,denoted by??s,are enhanced by a factor of ～*** improvements increase the number of detectable GW sources,facilitate multi-messenger follow-up observations and provide constraints on the cosmological constant.

关键词： space-based gravitational wave detection gravitational waves massive black hole binaries

Laser image refractive index sensor based on the combination of a coreless optical fiber and a digital camera

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Optoelectronics Letters 2025年第2期21卷 65-68页

作者： guo Jingzhong LAN feng CHEN Xiang LIU Haifeng Xi'an Institute of Space Radio Technology Key Laboratory of Optoelectronic Sensor and Sensing Network Technology College of Electronic Information and Optical Engineering Nankai University

As a laser passes through a scattering medium,the light interacts with the irregular reflections within the medium,resulting in light scattering and the formation of *** this paper,an image sensor based on the combination of a coreless optical fiber and a digital camera is proposed for liquid refractive index sensing *** coreless fiber is used as a sensing unit,and the change in the speckle pattern is measured using the digital correlation method to detect the magnitude of the liquid's refractive *** experimental results indicate that the laser image sensing technique is capable of effectively distinguishing liquid samples with refractive indices ranging from 1.332 8 to1.390 8,with a sensing sensitivity of-1.306 ***,the laser image sensing technique,with its advantages of high experimental reproducibility,simple system design,remote over-control,holds great research significance and potential application in laser communication and sensor integration.

关键词： Digital cameras

鼻内窥镜术后Medtronic海绵填塞术腔的效果观察

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中国组织工程研究与临床康复 2007年第22期11卷 4428-4429页

作者：曾立刚冯国琴华中科技大学同济医学院附属襄樊医院耳鼻咽喉科湖北省襄樊市441021

为了解Medtronic海绵在鼻内镜鼻窦手术后填塞术腔的效果,选择华中科技大学同济医学院附属襄樊医院耳鼻咽喉科2004-06/12收治的鼻内窥镜术后患者76例,随机分为Medtronic海绵组36例和凡士林纱条组40例,分别采用Medtronic海绵或凡士林纱条... 详细信息

为了解Medtronic海绵在鼻内镜鼻窦手术后填塞术腔的效果,选择华中科技大学同济医学院附属襄樊医院耳鼻咽喉科2004-06/12收治的鼻内窥镜术后患者76例,随机分为Medtronic海绵组36例和凡士林纱条组40例,分别采用Medtronic海绵或凡士林纱条填塞术腔,观察两组患者术后鼻部胀痛及止血效果情况。结果发现Medtronic海绵组术后胀痛发生率明显低于凡士林纱条组(P<0.01),Medtronic海绵组取出填塞物时出血发生率明显也低于凡士林纱条组(P<0.01)。说明了Medtronic海绵用于鼻内窥镜术后术腔填塞效果明显优于凡士林纱条,有利于鼻内窥镜术后患者的恢复。

关键词： Medtronic海绵凡士林纱条鼻内窥镜鼻腔填塞

个体化预测非小细胞肺癌患者化疗期间肺部感染风险Nomogram模型的建立与验证

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中国感染控制杂志 2022年第2期21卷 171-179页

作者：张俐丽冯国琴泰州市人民医院呼吸与危重症医学科江苏泰州225300 泰州市人民医院护理部江苏泰州225300

目的构建个体化预测非小细胞肺癌(NSCLC)患者化学治疗(化疗)期间发生肺部感染的风险Nomogram模型,并对模型的预测效能进行验证。方法选取2018年2月—2021年1月在某院进行治疗的218例NSCLC患者作为研究对象,根据化疗后是否发生肺部感染... 详细信息

目的构建个体化预测非小细胞肺癌(NSCLC)患者化学治疗(化疗)期间发生肺部感染的风险Nomogram模型,并对模型的预测效能进行验证。方法选取2018年2月—2021年1月在某院进行治疗的218例NSCLC患者作为研究对象,根据化疗后是否发生肺部感染将其分为肺部感染组(n=56)和非肺部感染组(n=162),采用LASSO和logistic回归分析筛选NSCLC患者化疗期间发生肺部感染的独立危险因素,并构建Nomogram预测模型。结果纳入218例NSCLC患者,56例化疗期间发生肺部感,感染发病率为25.69%。LASSO和logistic回归分析结果显示:年龄≥60岁、糖尿病、联合化疗药物、化疗周期>2次、化疗后清蛋白含量<30 g/L、化疗前KPS评分<80分是NSCLC患者化疗期间发生肺部感染的独立预测因素(均P<0.05)。基于6项独立预测因素建立预测NSCLC患者化疗期间发生肺部感染的风险Nomogram模型,验证结果显示,训练集和验证集的C-index分别为0.819(95%CI:0.788~0.850)、0.802(95%CI:0.778~0.829),两集校准曲线走向与对角线(理想曲线)较为贴近,受试者工作特征曲线下面积分别为0.807(95%CI:0.775~0.839)、0.797(95%CI:0.773~0.821),决策曲线显示阈值概率在1%~90%时,有较高的净获益值。结论基于NSCLC患者化疗期间发生肺部感染独立预测因素建立的Nomogram模型,具有较好的预测效能,有助于临床及早筛查高风险患者和进一步改进治疗计划。

关键词：非小细胞肺癌肺部感染预测 Nomogram模型预测因素

Studies on Stimulating Effect of Two Selective Insecticides on the Numbers of Laid Egg by Yellow Rice Borer,Tryporyza incertulas(Walker)and Their Effects on Biochemistry of Rice Plants

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Agricultural Sciences in China 2003年第10期2卷 1121-1129页

作者： WU Jin-cai, WANG Ai-hua, XU Jun-feng, YANG guo-qin, QIU Hui-min and LI Dong-hu (Department of Plant Protection, Agricultural College, Yangzhou University, Yangzhou 225009, P.R.China ) Department of Plant Protection Agricultural College Yangzhou University Yangzhou 225009 P. R. China

Buprofezin and imidacloprid are selective insecticides against Homoptera insects. This paper investigated stimulating effect of the two insecticides on the number of laid eggs by yellow rice borer, Tryporyza incertulas(Walker) of three generations in 20012002. The results showed that the reproductive rate of emergence months during the larvae feeding on the rice plants of Xiushui63 treated with the two insecticides was significantly higher than that of control, indicating that the numbers of laid eggs by the borer was stimulated following buprofezin and imidacloprid applications. However, there was no such effect for the larvae feeding on rice variety Zhendao2 which showed moderate resistance to the insect. In addition, the incidence of stimulating egg laid for the first instar treated with the two insecticides was greater than that for the third instar. Biochemical tests showed that oxalic acid concentration declined, and photosynthetic rate of rice leaves following the two insecticide applications declined significantly compared to control, whereas reducing sugar concentration increased significantly for all other treatments of two varieties except Xiushui63 treated with buprofezin. The level of glutathione-S-transferase varied with rice variety and insecticide.

关键词： Buprofezin Imidacloprid Tryporyza incertulas Egg laid Stimulating effect Biochemical mechanism

Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology

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Neural Regeneration Research 2025年第9期20卷 2655-2666页

作者： Yiyang qin Wenzhen Zhu Tingting guo Yiran Zhang Tingting Xing Peng Yin Shihua Li Xiao-Jiang Li Su Yang Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)Guangdong–HongKong–Macao Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong ProvinceChina

Spinal and bulbar muscular atrophy is a neurodegenerative disease caused by extended CAG trinucleotide repeats in the androgen receptor gene,which encodes a ligand-dependent transcription facto *** mutant androgen receptor protein,characterized by polyglutamine expansion,is prone to misfolding and forms aggregates in both the nucleus and cytoplasm in the brain in spinal and bulbar muscular atrophy *** aggregates alter protein-protein interactions and compromise transcriptional *** this study,we reported that in both cultured N2a cells and mouse brain,mutant androgen receptor with polyglutamine expansion causes reduced expression of mesencephalic astrocyte-de rived neurotrophic *** n of mesencephalic astrocyte-derived neurotrophic factor amelio rated the neurotoxicity of mutant androgen receptor through the inhibition of mutant androgen receptor *** down endogenous mesencephalic astrocyte-derived neurotrophic factor in the mouse brain exacerbated neuronal damage and mutant androgen receptor *** findings suggest that inhibition of mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor is a potential mechanism underlying neurodegeneration in spinal and bulbar muscular atrophy.

关键词： androgen receptor mesencephalic astrocyte-derived neurotrophic factor mouse model neurodegeneration neuronal loss neurotrophic factor polyglutamine disease protein misfolding spinal and bulbar muscular atrophy transcription factor