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Chinese Chemical Letters 2006年第8期17卷 1113-1116页

作者： Hua Li JIA feng he jun feng Ren Xi ZHUO Key Laboratory of Biomedical Polymers of Ministry of Education Department of Chemistry Wuhan University Wuhan 430072

Novel amphiphilic triblock copolymer poly（p-dioxanone-co-5-benzyloxytrimethylene carbonate）-block-poly（ethylene glycol）-block-poly（p-dioxanone-co-5-benzyloxytrimethylene carbonate）（p（PDO-co-BTMC）-b-PEG-b-p（PDO-co-BTMC）） was successfully synthesized using immobilized porcine pancreas lipase on porous silica particles （IPPL） as the catalyst for the fLrSt time. 1H NMR, 13C NMR and GPC analysis were used to confirm the structures of resulting copolymers. The molecular weight （Mn） of the copolymer with feed ratio of 69：20：11 （BTMC： PDO： PEG ） was 31300 g/mol and the polydispersity was 1.85, while the Mn decreased to 25000 g/mol and polydispersity of 1.93 with the feed ratio of 50：40：10.

关键词： Amphiphilic copolymer poly(ethylene glycol) 5-benzyloxytrimethylene carbonate,p-dioxanone enzymatic polymerization.

Left armpit subcutaneous metastasis of gastric cancer: A case report

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World Journal of Clinical Cases 2019年第23期7卷 4137-4143页

作者： feng-jun he Peng Zhang Mo-Jin Wang Yi Chen Wen Zhuang Department of Gastrointestinal Surgery West China Hospital Sichuan University

BACKGROUND Gastric cancer is the third most lethal malignant tumor *** has always been a major cause of poor *** evidence shows that the most common sites for metastasis of gastric carcinoma are the liver(48%),peritoneum(32%),lung(15%),and bone(12%);however,subcutaneous metastasis is are and occurs in approximately 0.8%of *** report a rare case of armpit subcutaneous metastasis of gastric *** best surgical window was missed,as a result of lacking attention of the *** SUMMARY A 69-year-old man who had previously undergone radical gastrectomy and received eight cycles of oral chemotherapy for gastric cancer showed a rapidly growing mass in his the left armpit;within just 3 mo,the mass grew to a size of 6.9 cm×4.4 cm×5.7 *** Doppler ultrasonography and Positron emission tomography/computed tomography prompted the possibility of metastasis of the *** needle aspiration biopsy guided by color Doppler ultrasound showed the presence of cancer cells in the *** examination showed CDX-2(+),PCK(+),CK20(+),CK7(-),and TTF(-),which supported the metastasis of gastric *** the risk of resection,the patient did not undergo surgical *** The case indicates that unidentified subcutaneous masses in patients with a history of gastric cancer should be carefully evaluated.

关键词： Stomach neoplasms Neoplasm metastasis Subcutaneous Case report Cancer therapy Skin neoplasms

Effect of acupuncture at different meridian acupoints on changes of related factors for rabbit gastric mucosal injury

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World Journal of Gastroenterology 2005年第41期11卷 6472-6476页

作者： Jie Yan Ren-Da Yang jun-feng he Shou-Xiang Yi Xiao-Rong Chang Ya-Ping Lin Department of Acupuncture and Moxibustion Hunan College of Traditional Chinese MedicineChangsha 410007 Hunan Province China

AIM： To explore the regularity of multi-meridians controlling a same viscus （MMCSV）. METHODS： The rabbit gastric ulcer model was established by ethanol intragastric instillation. Fifty-six rabbits were randomly divided into normal group, model group （MG）, model plus acupuncture at Foot Yangming Meridian group （YMG）, model plus acupuncture at Foot Taiyin Meridian group （TYG）, model plus acupuncture at Foot Shaoyang Meridian group （SYG）, model plus acupuncture at Foot Jueyin Meridian group （JYG）, model plus acupuncture at Foot Taiyang Meridian group （TYMG）, with eight rabbits in each group. Gastric mucosal nitric oxide （NO） and nitric oxide synthase （NOS） were assayed by the nitric acid reductase method, and prostaglandin E2 （PGE2） and epidermal growth factor （EGF） were measured by radioimmunoassay. The comprehensive effects were analyzed by weighing method. RESULTS： Compared to MG, SYG, JYG and TYMG, the rabbits gastric mucosal injury index （GMII） reduced very significantly in YMG （P〈0.01）. Compared to MG, the GMII also reduced significantly in TYG （P〈0.05）. NO, NOS, PGE2 and EGF increased very significantly in YMG （P〈0.01）. The EGF in YMG also increased significantly than that in TYG compared to those in MG, SYG, JYG and TYMG （P〈0.05）. The PGE2 and EGF also increased very significantly in TYG than those in MG, JYG and TYMG （P〈0.01）. While compared to SYG, the NOS increased significantly in TYG （P〈0.05）. NOS was the highest in YMG （P〈0.01）, and was higher in TYG than in MG （P〈0.01）. CONCLUSION： MMCSV is common. The Foot Yangming Meridian is most closely related to the stomach, followed by Foot Taiyin Meridian, Foot Shaoyang Meridian and Foot Jueyin Meridian. Foot Taiyang Meridian has no correlation with the stomach.

关键词： Relationship between Meridian and Viscus Gastric mucosal injury/acupuncture effects MMCSV

Effect of electroacupuncture at Sibai on the gastric myoelectric acitivities of denervated rats

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World Journal of Gastroenterology 2006年第36期12卷 5897-5901页

作者： Xiao-Rong Chang Jie Yan Yan-Ling Zhao Jiang-Shang Li Jian-Hua Liu jun-feng he College of Acupuncture and Massage Hunan University of Traditional Chinese Medicine Changsha 410007 Hunan Province China

AIM： To explore the mechanism of the exciting effects of electro-acupuncture （EA） at Sibai on the gastric myoelectric activities. METHODS： A total of 32 rats were randomly divided into four groups. Through intraperitoneal injection with atropine （the anti-cholinergic agent by blockade of muscarinic receptors）, hexarnethonium （automatic nerve ganglion-blocking agent） and reserpine （anti-adrenergic agent by depleting the adrenergic nerve terminal of its norepinephrine store）, effects of EA at Sibai on the gastric myoelectric activities of the denervated rats were observed. RESULTS： After intraperitoneal injection of atropine and hexamethonium, the average amplitude and ratio of period to time in the phase of high activity of gastric myoelectric slow wave, and the average numbers of the peaks of gastric myoelectric fast wave were significantly decreased （P 〈 0.01, P 〈 0.05, P 〈 0.01）, while after intraperitoneal injection of reserpine, the aforementioned three parameters were increased （P 〈 0.01, P 〈 0.05, P 〈 0.01）. EA at Sibai point partially relieved the inhibitory effect of atropine and hexamethonium on the gastric myoelectric activities in the rats （P 〈 0.05 or P 〉 0.05）. CONCLUSION： Cholinergic and adrenergic nervous systems and autonomic nerve ganglion participate in the peripheral passage of the controlling effects of EA at Foot Yangming Channel on gastrointestinal tract.

关键词： Electro-acupuncture Rats Sibai Nerve block Gastric myoelectric activities

Implementation of Phase Generated Carrier Technique for FBG Laser Sensor Multiplexed System Based on Compact RIO

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Journal of Electronic Science and Technology of China 2008年第4期6卷 385-388页

作者： Lei feng jun he Jing-Yuan Duan Fang Li Yu-Liang Liu Optoelectronics System Laboratory Institute of Semiconductors ChineseAcademy of Sciences Beijing 100083 China

This paper presents the fundamental technique of phase generated carrier （PGC） and its realization on compact reconfigurable input and output （RIO） which adopts real-time and field programmable grate array （FPGA） techniques. Improvement of the PGC technique is also introduced by using peak-to-peak value detection method to reduce the influence of variation of the light intensity. A four-element fibre Bragg gratings （FBG） laser sensor system is conducted in the experiment and the demodulated results demonstrate correlation coefficient as high as 0.995 with the reference signal and the dynamic range to be 120dB@63Hz.

关键词： Compact reconfigurable input andoutput (RIO) demodulation fibre Bragg gratings(FBG) laser sensor multiplexed system phase generatedcarrier (PGC).

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列车随机激振荷载的数值模拟

振动与冲击 2008年第2期27卷 49-52页

作者：冯军和闫维明北京工业大学工程抗震与结构诊治北京市重点实验室北京100022

列车荷载模拟是列车诱发环境振动分析中的首要步骤,同时列车荷载模拟的合理性也直接影响着环境振动的分析结果。针对目前工程中较为常用的两种列车随机激振荷载数值模拟方法进行了研究,分析了这两种方法的局限性。通过引入频响函数及轨... 详细信息

列车荷载模拟是列车诱发环境振动分析中的首要步骤,同时列车荷载模拟的合理性也直接影响着环境振动的分析结果。针对目前工程中较为常用的两种列车随机激振荷载数值模拟方法进行了研究,分析了这两种方法的局限性。通过引入频响函数及轨道不平顺谱优化了列车荷载数值算法及计算模型,并在数值计算中采用傅里叶快速数值算法,提高列车荷载的模拟的效率和可靠性。最后,通过实际算例的模拟论证了这两种新方法的合理性和高效性。

关键词：列车荷载傅里叶快速变换数值模拟

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美国沸石咪唑酯骨架结构材料的研究进展

现代化工 2008年第6期28卷 81-84,86页

作者：刘漫鲁晓明冯俊鹤韩丽首都师范大学化学系北京100037

介绍了美国新一代沸石咪唑酯骨架结构材料的组装和吸附二氧化碳性能方面的研究进展。新一代沸石咪唑酯骨架结构材料(ZIFs)是一类具有可调整孔洞大小及化学性质的多孔材料,具有高度稳定性和结构多样性,可选择性地高效捕获和存储二氧化碳。

关键词： ZIFs 多孔二氧化碳吸附

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轨道不平顺随机过程的数值模拟

世界地震工程 2008年第1期24卷 103-109页

作者：张立伟冯军和黑龙江工程学院黑龙江哈尔滨150050 北京工业大学工程抗震与结构诊治北京市重点实验室北京100022

轨道不平顺是列车-轨道系统的动力响应的主要影响因素,不平顺样本是列车-轨道系统动力分析模型中不可缺少的参数。根据随机理论原理推导了轨道不平顺谱的空间、时间域的相互转化关系,得到了时域功率谱的表达式。分析了目前广泛应用几种... 详细信息

轨道不平顺是列车-轨道系统的动力响应的主要影响因素,不平顺样本是列车-轨道系统动力分析模型中不可缺少的参数。根据随机理论原理推导了轨道不平顺谱的空间、时间域的相互转化关系,得到了时域功率谱的表达式。分析了目前广泛应用几种轨道不平顺随机过程的模拟方法的原理及作法,通过对功率谱快速数值算法的分析给出了一种新三角级数模拟方法,该方法与逆傅氏变换法具有等效性,同时也论证了逆傅氏变换方法样本是高斯过程。最后通过实际算例的分析论证了新三角级数法与傅氏逆变换法在简便、合理等方面的优点。

关键词：随机过程功率谱密度轨道不平顺数值模拟

Identification of Dual Receptor-binding Specific Strains of Human H5N1 Viruses in China

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Biomedical and Environmental Sciences 2012年第1期25卷 104-108页

作者： ZHOU Jian Fang ZOU Shu Mei LI Zi WANG Min DONG Jie GUO jun feng WEI he Jiang WEN Le Ying XU Hong SHU Yue Long State Key Laboratory for Molecular Virology and Genetic Engineering National Institute for Viral Disease Control and Prevention China CDC Beijing 102206 China

Objective Both the 2, 6 linkage and its topology on target cells are critical for the recognition by human influenza virus. The binding preference of avian flu virus H5N1 HA to the 2, 3-1inked sialylated glycans is considered the major factor limiting its efficient infection and transmission in humans. To monitor potential adaptation of H5N1 virus in human population, the surveillance of receptor-binding specificity was undertaken in China. Methods The binding specificity of 32 human H5N1 virus strains isolated from 2003 to 2009 was tested by 2, 3-specific sialidase-treated chicken red blood cell （CRBC） agglutination assay and a solid-phase direct binding assay with synthetic sialylglycopolymers. Results Dual binding preference to 2, 3 and 2, 6-glycans were found in two strains： A/Guangdong/1/06 （A/GD/1/06） and A/Guangxi/1/08 （A/GX/1/08）. Though minor effect of short-2, 6-binding was detected in A/GX/1/08 at a low virus titer, both showed high affinity to the oligosaccharide at a high load. Notably both are of the long-2, 6-recognition, with the same topology as that of human H1N1 and H3N2 viruses. Conclusion The findings suggest that human H5N1 virus in China likely acquired the potential human-adaptation ability. Further research and surveillance on receptor-binding specificity of H5N1 viruses are required.

关键词： Receptor-binding specificity Human H5N2 virus China

基于Epsilon约束法的短纤维生产调度的双目标优化研究

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运筹与管理 2018年第3期27卷 1-8页

作者：郑斐峰何俊凯刘明东华大学旭日工商管理学院上海200051 同济大学经济与管理学院上海200092

针对短纤维生产行业实际,本文综合考虑客户的需求差异、客户的重要程度、纤维生产设备的准备时间以及交货期差异等因素,研究连续需求下的短纤维生产排序优化问题。首先,本文建立双目标整数规划模型,即最小化客户订单总延迟和最小化机器... 详细信息

针对短纤维生产行业实际,本文综合考虑客户的需求差异、客户的重要程度、纤维生产设备的准备时间以及交货期差异等因素,研究连续需求下的短纤维生产排序优化问题。首先,本文建立双目标整数规划模型,即最小化客户订单总延迟和最小化机器总准备时间;其次,设计Epsilon约束算法并调用CPLEX精确求解调度方案,即帕累托前沿;最后设计非支配排序的遗传算法(NSGA-Ⅱ)求解大规模生产下的调度优化方案。通过实验,证明该整数规划模型和算法对解决多客户连续需求问题具有实际价值,进而可以为短纤维生产企业提供参考。

关键词：短纤维生产调度双目标整数规划 Epsilon约束算法 NSGA-Ⅱ算法