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Expression of pIgR in the tracheal mucosa of SHIV/SIV-infected rhesus macaques

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Zoological Research 2017年第1期38卷 44-48页

作者： Dong Li feng-Jie wang Lei yu wen-Rong Yao yan-Fang Cui Gui-Bo yang National Institute of AIDS/STD Control and Prevention China-CDC Beijing 102206 China

Polymeric immunoglobulin receptors（pIgR） are key participants in the formation and secretion of secretory Ig A（S-Ig A）, which is critical for the prevention of microbial infection and colonization in the respiratory system. Although increased respiratory colonization and infections are common in HIV/AIDS, little is known about the expression of pIgR in the airway mucosa of these patients. To address this, the expression levels of pIgR in the tracheal mucosa and lungs of SHIV/SIV-infected rhesus macaques were examined by real-time RTPCR and confocal microscopy. We found that the levels of both PIGR m RNA and pIgR immunoreactivity were lower in the tracheal mucosa of SHIV/SIVinfected rhesus macaques than that in non-infected rhesus macaques, and the difference in pIgR immunoreactivity was statistically significant. IL-17 A, which enhances pIgR expression, was also changed in the same direction as that of pIgR. In contrast to changes in the tracheal mucosa, pIgR and IL-17 A levels were higher in the lungs of infected rhesus macaques. These results indicated abnormal pIgR expression in SHIV/SIV, and by extension HIV infections, which might partially result from IL-17 A alterations and might contribute to the increased microbial colonization and infection related to pulmonary complications in HIV/AIDS.

关键词： Tracheal mucosa Lungs plgR SHIV/SIV infection IL-17A

Weakly Nonlinear Rayleigh–Taylor Instability in Cylindrically Convergent Geometry

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Chinese Physics Letters 2018年第5期35卷 65-68页

作者： Hong-yu Guo Li-feng wang wen-Hua Ye Jun-feng Wu Wei-yan Zhang Graduate School China Academy of Engineering Physics Beijing 100088 Institute of Applied Physics and Computational Mathematics Beijing 100094 HEDPS Center for Applied Physics and Technology Peking University Beijing 100871

The Rayleigh–Taylor instability（RTI） in cylindrical geometry is investigated analytically through a second-order weakly nonlinear（WN） theory considering the Bell–Plesset（BP） effect. The governing equations for the combined perturbation growth are derived. The WN solutions for an exponentially convergent cylinder are obtained. It is found that the BP and RTI growths are strongly coupled, which results in the bubble-spike asymmetric structure in the WN stage. The large Atwood number leads to the large deformation of the convergent interface. The amplitude of the spike grows faster than that of the bubble especially for large mode number m and large Atwood number A. The averaged interface radius is small for large mode number perturbation due to the mode-coupling effect.

关键词： RT In Taylor Instability in Cylindrically Convergent Geometry Weakly Nonlinear Rayleigh

Weakly Nonlinear Rayleigh-Taylor Instability in Incompressible Fluids with Surface Tension

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Chinese Physics Letters 2017年第4期34卷 60-63页

A weakly nonlinear model is established for incompressible Rayleigh-Taylor instability with surface tension. The temporal evolution of a perturbed interface is explored analytically via the third-order solution. The dependence of the first three harmonics on the surface tension is discussed. The amplitudes of bubble and spike are greatly affected by surface tension. The saturation amplitude of the fundamental mode versus the Atwood number A is investigated with surface tension into consideration. The saturation amplitude decreases with increasing A. Surface tension exhibits a stabilizing phenomenon. It is shown that the asymmetrical development of the perturbed interface occurs much later for large surface tension effect.

关键词： RAYLEIGH-Taylor instability NONLINEAR systems INCOMPRESSIBLE flow (Fluid mechanics) FLUIDS SURFACE tension

PCR-RFLP and AP-PCR of rbcL and ITS of rDNA Show That × Taxodiomeria peizhongii （ Taxodium × Cryptomeria） Is not an Intergeneric Hybrid

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Journal of Integrative Plant Biology 2006年第4期48卷 468-472页

作者： yan Ling Wei-feng Lu Fan Lu yu-Guo wang Jia-Kuan Chen wen-Ju Zhang The Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering Institute of Biodiversity Science Fudan University Shanghai 200433 China

Taxodiorneria peizhongii Z. J. Ye, J. J. Zhang et S. H. Pan was regarded as a new Intergenerlc hybrid between Taxodlum mucronatum Tenore （as the female donor） and Cryptomeria fortunei Hoolbrenk ex Otto et Dletr （as the male donor）. To confirm the authenticity of the intergeneric hybrid, we analyzed the rbcL gene and the Internal transcribed spacer （ITS） of 26S-18S ribosomal RNA gene of the three species using polymerase chain reaction-restriction fragment length polymorphism （PCR-RFLP） and arbitrarily primed PCR （AP-PCR）, and ob- tained the following results：i） Taxodiomeria peizhongii had the same RFLP maps of the rbcL gene and the ITS as Taxodlum mucronatum, but was different from C. fortunei; II） a 311-bp PCR amplification product was obtained In C. fortunei by AP-PCR of ITS, but was not found in Taxodiomeria peizhongii. Our results have demonstrated that C. fortunei did not provide any genome for Taxodiomeria peizhongii, Implying that T. peizhongii Is not an Intergenerlc hybrid between the two species.

关键词： Arbitrary Primed-Polymerase Chain Reaction (AP-PCR) intergeneric hybrid nuclear and chloroplast genome pater- nally inherited polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) × Taxodiomeria peizhongii.

Development of limestone calcined clay cement concrete in South China and its bond behavior with steel reinforcement

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2020年第11期21卷 892-907页

作者： Zhen-yu HUANG You-shuo HUANG wen-yu LIAO Ning-xu HAN Ying-wu ZHOU feng XING Tong-bo SUI Bin wang Hong-yan MA Guangdong Provincial Key Laboratory of Durability for Marine Civil Engineering Shenzhen UniversityShenzhen 518060China Department of Civil Architectural and Environmental EngineeringMissouri University of Science and TechnologyRollaMO 65401USA Si noma Research Institute Si noma International Engineering Co.Ltd.Beijing 100102China

Limestone calcined clay cement(LC^3),consisting of ordinary Portland cement(OPC)clinker,calcined clay,limestone powder,and gypsum,has been considered a promising solution to current challenges in the cement and concrete industry,such as high carbon emissions,high energy consumption,and resource *** study carries out a series of experimental investigations of LC^3-based paste,mortar,and concrete,including microstructural analyses(*** product characterization and pore structure analysis)and macro-scale testing(*** and mechanical properties),using raw materials from south *** results show that,in LC^3 paste,the replacement of clinker by calcined clay and limestone leads to an increased volume of small pores but decreased total volume of *** workability of LC^3 mortar and concrete can be readily tailored using conventional *** designed for comparable 28-d compressive strength,the LC^3 mortar and concrete tend to have lower early-age compressive strength,but comparable compressive strength and higher flexural strength than those of the OPC counterparts at late *** study also examines the bond-slip behavior between LC^3 concrete and steel bars and finds that the bond strength is comparable to that of OPC concrete with the same 28-d compressive strength,but that the LC^3 concrete-rebar interface exhibits higher bond-slip *** findings on LC^3 concrete provide fundamental information and guidance for furthering the application of LC^3 binder in structural concrete in the near future.

关键词： Limestone calcined clay cement(LC^3) Hydration Bond-slip Mercury intrusion porosimetry(MIP) Scanning electron microscope(SEM) Bond strength

Optical and X-Ray Observations of MAXI J1820+070 During the Early Outburst Phase in 2018:Zooming in the Low Frequency QPOs

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Research in Astronomy and Astrophysics 2022年第4期22卷 106-113页

作者： Dong-Ming Mao wen-Fei yu Ju-Jia Zhang Zhen yan Stefano Rapisarda Xiao-feng wang Jin-Ming Bai Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China University of Chinese Academy of Sciences Beijing 100049China yunnan Observatories Chinese Academy of SciencesKunming 650011China Key Laboratory for the Structure and Evolution of Celestial Objects CASKunming 650216China Physics Department Tsinghua UniversityBeijing 100084China Beijing Planetarium Beijing Academy of Sciences and TechnologyBeijing 100044China

We report a further investigation of the optical low frequency quasi periodic oscillations(LF QPOs)detected in the black hole transient MAXI J1820+070 in the 2018 observations with the YFOSC mounted on Lijiang 2.4 m telescope(LJT).In addition,we make use of the Insight-HXMT/HE observations to measure the properties of the quasi-simultaneous X-ray LF QPOs of MAXI J1820+070 on the same *** compared the centroid frequency,the full width at half maximum(FWHM)and the fractional rms of the LF QPOs in both wavelength *** found that the centroid frequency of the optical QPO is at a frequency of 51.58 m Hz,which is consistent with that of the X-ray LF QPO detected on the same day within 1 m *** also found that the FWHM of the optical LF QPO is significantly smaller than that of the X-ray LF QPO,indicating that the optical QPO has a higher *** quasi-simultaneous optical and the X-ray LF QPO at a centroid frequency of about 52 m Hz suggests that the actual mechanisms of these LF QPOs as the Lense-Thirring precession should work in the vicinity of a radius of about 80-117 gravitational radii(R_(g)=GM/c^(2),M is the mass of the black hole)from the black hole if the QPO frequency is related to a proxy of the orbital frequency in the accretion fiow as the Lense-Thirring precession model ***,the apparent higher coherence of the optical QPO favors that it is a more original signal as compared with the X-ray QPO.

关键词： X-ray stars Low mass binary stars X-ray transient sources

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai wenyong Cai Wujun Cai Yijian Cai Yizhou Cai yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng yunlong Chi Pietro Chimenti wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

Primary Squamous Cell Carcinoma of the Small Intestine： Pathogenesis and Clinical Features

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Chinese Medical Journal 2016年第17期129卷 2131-2133页

作者： feng-Dan wang Zhi-Weiwang Hua-Dan Xue Huan-wen Wu yan Zhang Jian-Chun yu Zheng-yu Jin Department of Radiology Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100730 China Department of Pathology Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100730 China Department of General Surgery Peking Union Medical College Hosl~ital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100730 China

Relative to the length and surface area of the gastrointestinal tract, malignant tumors of the small intestine are remarkably rare, with a global incidence of〈1 per 100,000 population. Among the forty different histological subtypes of small intestinal cancers, primary squamous cell carcinoma （SCC） is exceptionally rare with only occasional case reports in literature. The present study reported a case of primary SCC of the small intestine and reviewed all cases reported in English literature to provide a systematic overview of this rare disease.

关键词： Positron Emission Tomography Primary Squamous Cell Carcinoma Small Intestine

Infrared autofluorescence, short-wave autofluorescence and spectral-domain optical coherence tomography of optic disk melanocytomas

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International Journal of Ophthalmology(English edition) 2016年第5期9卷 713-716页

作者： Peng Zhang yan-Nian Hui wen-Qin Xu Zi-feng Zhang Hai-yan wang Dong-Jie Sun yu-Sheng wang Department of Ophthalmology Eye Institute of Chinese PLAXijing Hospitalthe Fourth Military Medical University

AIM： To investigate the findings of infrared fundus autofluorescence（IR-AF） and spectral-domain optical coherence tomography（SD-OCT） in eyes with optic disc melanocytoma（ODM）.· METHODS： IR-AF findings and those of other ophthalmologic imaging examinations, including short-wave autofluorescence（SW-AF）, fluorescein angiography（FA）, fundus color photography, and SD-OCT of 8 eyes of 8 consecutive cases with ODM were assessed.·RESULTS： The ODMs in all cases（100%） presented similar IR-AF, SW-AF, and FA findings. On IR-AF images, ODMs showed outstanding hyper-AF with well-defined outline. On SW-AF images, the area of ODMs presented as hypo-AF. FA images revealed the leaking retinal telangiectasia on the surface of the ODMs. On SDOCT images in 8 cases（100%）, the ODMs were sloped with highly reflective surface, which were disorganized retina and optic nerve layers. In 7 cases（87.5%）, peripapillary choroids were involved. The melanocytomas of 8 cases（100%） presented as optically empty spaces. Vitreous seeds were found in one case（12.5%）.· CONCLUSION： IR-AF imaging may provide a new modality to evaluate the pathologic features of ODMs,and together with SW-AF imaging, offers a new tool to study biological characteristics associated with ***-OCT is a valuable tool in delimitating the tumor extension and providing morphological information about the adjacent retinal tissue.

关键词： melanocytoma angiography autofluorescence optical coherence tomography