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Searching for^(76)Ge neutrinoless double beta decay with the CDEX-1B experiment

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Chinese Physics C 2024年第10期48卷 11-22页

作者： bing-Tao zhang Jun-zheng Wang li-Tao yang Qian Yue Ke-Jun Kang yuan-jing li Hai-Peng An C.Greeshma jian-Ping Chang Yun-Huan Chen jian-Ping Cheng Wen-Han Dai Zhi Deng Chang-Hao Fang Xin-Ping Geng Hui Gong Qiu-Ju Guo Xu-yuan Guo li He Sheng-Ming He jin-wei Hu Han-Xiong Huang Tu-Chen Huang Hai-Tao jia Xi jiang S.Karmakar Hao-Bin li jian-Min li jin li Qian-Yun li Ren-Ming-jie li Xue-Qian li Yu-Lan li Yi-Fan liang Bin liao Fong-Kay lin Shin-Ted lin jia-Xuan liu shu-Kui liu yan-Dong liu Yu liu yuan-yuan liu Zhong-Zhi liu Hao Ma Yu-Cai Mao Qi-yuan Nie jin-Hua Ning Hui Pan Ning-chun Qi jie Ren Xi-Chao Ruan Ze She Manoj Kumar Singh tian-Xi sun Chang-jian Tang wei-You Tang yang tian Guang-Fu Wang li Wang Qing Wang Yu-feng Wang Yun-Xiang Wang Henry-Tsz-King Wong Shi-Yong Wu Yu-Cheng Wu Hao-yang Xing Rui Xu Yin Xu Tao Xue Yu-Lu yan Nan Yi chun-Xu Yu Hai-Jun Yu jian-feng Yue Ming Zeng Zhi Zeng feng-Shou zhang Lei zhang Zhen-Hua zhang Zhen-Yu zhang Kang-Kang Zhao Ming-Gang Zhao ji-Fang Zhou Zu-Ying Zhou jing-Jun Zhou Key Laboratory of Particle and Radiation Imaging(Ministry of Education)and Department of Engineering Physics Tsinghua UniversityBeijing 100084 Department of Physics Tsinghua UniversityBeijing 100084 Institute of Physics Academia SinicaTaipei 11529 NUCTECH Company Beijing 100084 yaLong River Hydropower Development Company Chengdu 610051 College of Nuclear Science and Technology Beijing Normal UniversityBeijing 100875 College of Physics Sichuan UniversityChengdu 610065 School of Physics Peking UniversityBeijing 100871 Department of Nuclear Physics China Institute of Atomic EnergyBeijing 102413 Sino-French Institute of Nuclear and Technology Sun Yat-sen UniversityZhuhai 519082 School of Physics Nankai UniversityTianjin 300071 Department of Physics Banaras Hindu UniversityVaranasi 221005 Department of Physics Beijing Normal UniversityBeijing 100875

We operated a p-type point contact high purity germanium(PPCGe)detector(CDEX-1B,1.008 kg)in the China jinping Underground Laboratory(CJPL)for 500.3 days to search for neutrinoless double beta(0νββ)decay of^(76)Ge.A total of 504.3 kg⋅day effective exposure data was *** anti-coincidence and the multi/single-site event(MSE/SSE)discrimination methods were used to suppress the background in the energy region of interest(ROI,1989–2089 keV for this work)with a factor of 23.A background level of 0.33 counts/(keV⋅kg⋅yr)was *** lower limit on the half life of^(76)Ge 0νββdecay was constrained as T_(1/2)^(0ν)>1.0×10^(23)yr(90%C.L.),corresponding to the upper limits on the effective Majorana neutrino mass:<3.2–7.5 eV.

关键词： neutrinoless double beta decay CDEX point-contact germanium detector ^(76)Ge

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves weiming An Rui An Daniele Paolo Anderle Stefan Antusch yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi yuanjie Bi tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen jinhui Chen ji-yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen tianlu Chen wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core shuangxue Deng wei-tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl yadong Ding Haiyi Dong jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP jiNR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

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Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： He-Xin liu Yue Huang Guang-Cheng Xiao Qing-Cui Bu jin-Lu Qu shu zhang shuang-Nan zhang shu-Mei jia Fang-Jun Lu Xiang Ma lian Tao wei zhang li Chen li-Ming Song Ti-Pei li Yu-Peng Xu Xue-Lei Cao Yong Chen Cong-Zhan liu Ce Cai Zhi Chang Gang Chen tian-Xiang Chen Yi-Bao Chen Yu-Peng Chen wei Cui wei-wei Cui jing-Kang Deng Yong-wei Dong yuan-yuan Du Min-Xue Fu Guan-Hua Gao He Gao Min Gao Ming-Yu Ge Yu-Dong Gu Ju Guan Cheng-Cheng Guo Da-wei Han jia Huo Lu-Hua jiang wei-chun jiang jing jin Yong-jie jin ling-Da Kong bing li Cheng-Kui li Gang li Mao-shun li wei li Xian li Xiao-Bo li Xu-Fang li yang-Guo li zheng-wei li Xiao-Hua liang jing-yuan liao Bai-Sheng liu Guo-Qing liu Hong-wei liu Xiao-jing liu Yi-Nong liu Bo Lu Xue-feng Lu Qi Luo Tao Luo Bin Meng Yi Nang jian-Yin Nie Ge Ou Na Sai Ren-Cheng Shang Xin-Ying Song liang sun Ying Tan You-li Tuo Chen Wang Guo-feng Wang Juan Wang ling-Jun Wang Weng-shuai Wang Yu-Sa Wang Xiang-yang Wen Bai-yang Wu Bo-bing Wu Mei Wu shuo Xiao Shao-lin Xiong He Xu jia-wei yang Sheng yang yan-ji yang Yi-Jung yang Qi-Bin Yi Qian-Qing Yin yuan You Ai-Mei zhang Cheng-Mo zhang Fan zhang Hong-Mei zhang Juan zhang Tong zhang Wan-Chang zhang Wen-Zhao zhang Yi zhang Yi-Fei zhang Yong-jie zhang yuan-Hang zhang Yue zhang Zhao zhang Zhi zhang Zi-liang zhang Hai-Sheng Zhao Xiao-Fan Zhao Shi-jie zheng yao-Guang zheng Deng-Ke Zhou jian-feng Zhou Yu-Xuan Zhu Ren-lin Zhuang Yue Zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China College of Physics Sciences&Technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China

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Biomedical and Environmental Sciences 2020年第12期33卷 893-905页

作者： MA yan ZHU Dong Shan CHEN Ren Bo SHI Nan Nan liU Si Hong FAN Yi Pin WU Gui Hui yaNG Pu Ye BAI jiang feng CHEN Hong CHEN li Ying feng Qiao GUO Tuan Mao HOU Yong HU Gui Fen HU Xiao Mei HU Yun Hong HUANG jin HUANG Qiu Hua HUANG Shao Zhen ji liang jiN Hai Hao LEI Xiao li chun yan li Min Qing li Qun Tang li Xian Yong liU Hong De liU jin Ping liU zhang MA Yu Ting MAO ya MO liu Fen NA Hui WANG jing wei SONG Fang li sun Sheng WANG Dong Ting WANG Ming Xuan WANG Xiao yan WANG Yin Zhen WANG Yu Dong WU wei WU Lan Ping XIAO yan Hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia yaNG chun yaNG Kai Jun yuan Sheng li zhang Gong Qi zhang jin Bo zhang lin Song ZHAO shu Sen ZHAO Wan Ying zheng Kai ZHOU Ying chun ZHU Jun Teng ZHU tian Qing zhang Hua Min WANG yan Ping WANG Yong yan 无 Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China Centre for Health Management and Policy Research School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012ShandongChina Institute of Information on Traditional Chinese Medicine China Academy of Chinese Medical SciencesBeijing 100700China Department of Tuberculosis The Public Health Clinical Center of ChengduChengdu 610066SichuanChina Department of Infectious Disease Shaanxi Infectious Disease HospitalXi'an 610113ShaanxiChina Department of Infectious Disease Yulin Chinese Medicine HospitalYulin 719000ShaanxiChina President's Office The First Hospital of QiqiharQiqihar 161005HeilongjiangChina Department of Traditional Chinese Medicine Shangluo Central HospitalShangluo 726000ShaanxiChina Department of Traditional Chinese Medicine The People's Hospital of QitaiheQitaihe 154603HeilongjiangChina Department of Scientific Research Xianyang Central HospitalXianyang 712000ShaanxiChina Department of traditional Chinese medicine The First Affiliated Hospital of Anhui University of Traditional Chinese MedicineHefei 230012AnhuiChina Department of Infectious Disease Heping Hospital Affiliated to Changzhi Medical CollegeChangzhi 046000ShanxiChina Department of Traditional Chinese Medicine Langfang Hospital of Chinese MedicineLangfang 065000HeibeiChina Department of Traditional Chinese Medicine Xingtai Hospital of Chinese MedicineXingtai 054001HeibeiChina Department of Traditional Chinese Medicine The People's Hospital of Guangxi Zhuang Autonomous RegionNanning 168600GuangxiChina Department of Traditional Chinese Medicine The First People'sHospital of FangchenggangFangchenggang 538001GuangxiChina Department of Traditional Chinese Medicine Mianyang Hospital of Traditional Chinese MedicineMianyang 621000SichuanChina Department of Traditional Chinese Medicine Liuzhou People's HospitalLiuzhou 545006GansuChina Department of Traditional Chinese Medici

Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains *** A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of *** Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two *** Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes.

关键词： Comorbidities COVID-19 Severity Gender Age Treatment outcome

Consensus statement on layout and delivery of automatic external defibrillator in China

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Journal of Hainan Medical University 2020年第15期26卷 18-23页

作者： Yu Cao Song Chen yan-Fen Chai Xiao-Hui Chen Yu-Guo Chen Shao-Wen Cheng Wen-wei Cheng Bang-Han Ding yang Deng jie Fu Bang-jiang Fang Mai-Ying Fan li Gui Ping Gong wei Guo shu-Bin Guo liang Huang ji-yuan Han Zhong ji Xian-Fei ji Xin-Cai ji Hong-Xu jin Xin-Jun jiang Wang-Xiang jiang jia-liang liu Xiao-Ran liu Zhi liu Chuan-Zhu Lv feng Lu Tan-Shi li Xin li Yong li Shang-Lun li shuang-Ming li Xiao-Gang li Bao-Jun li Pei-Wu li chun-Sheng li Zhi-Jun li Chang-Luo li Xiang-Min li Yin-Ping li Zong-Jun Lu Zu-Xun Lu Zhong-Qiu Lu Zhi-Qian Luo Xiao-Xing liao jian-Bo Lei Tao Ma Yu Ma Yue-feng Ma Qing-Bian Ma lin-Hao Ma Jun-Qi Ma Shi-Nan Nie jie-Miao Ou-yang Peng Peng Qiao Pei shu-Ming Pan Guo-Zhong Qing li-jie Qin Wu-Ying Qiao Fei Shao wei Song Xing-Yue Song Zhen-Ju Song Rong-Ju sun De-ya Shang Du-Juan Sha Gui-Lan Tao Guo-Gang tian Ying-Ping tian jian-Guang tian Chao-yang Tong Zi-Ren Tang Meng-Xiong Tang Guo-Ping Wu Zhi Wan Tao Wang Xin Wang Peng Wang Zhong Wang Tong Wang Ri-Xing Wang Yi-Xin Wang Xiao-Dan Wang ling Wu wei wei Hua Xiang feng Xu Jun Xu jie Xu Miao-Rong Xie shuo-Gui Xu Tie Xu feng Yu Wen Yi li-Shan yang Shi-jiao yan jin-jian yao Shou-chun yan Xue-Zhong Yu Xian-Zhi Ye Xian-liang yan Fu-bing Zhou Rong-Bin Zhou Ming Zhou Qiang Zhou jin Zhou Ping Zhou Chang-Ju Zhu Hua-Dong Zhu ji-Hong Zhu Hong zhang Mao zhang Hua zhang Na zhang Guo-Qiang zhang Guo-Xiu zhang jin-Song zhang Wen-Wu zhang Wen-Zhong zhang jian-feng zhang Yi-Min Zhu Jun Zeng yuan zheng Zhi-jie zheng Shen Zhao yan Zhao Min Zhao Bin Zhao Xiao-Dong Zhao Xiao-jing Zhao Hong-Ke Zeng Sheng-Qiang Zou The Chinese Society of Emergency Medicine Research Unit of Island Emergency Medicine Chinese Academy of Medical SciencesHainan Medical University Key Laboratory of Emergency and Trauma of Ministry of Education Hainan Medical UniversityHaikouHainanChina Emergency and Trauma College Hainan Medical UniversityHaikouHainanChina Department of Emergency Hainan Clinical Research Center for Acute and Critical DiseasesThe Second Affiliated Hospital of Hainan Medical UniversityHaikouHainanChina Key Laboratory of Hainan Trauma and Disaster Rescue Key Laboratory of Trauma of Hainan Medical University

*** Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac *** is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].

关键词： cardiac death respiratory

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肺癌适应性治疗中国专家共识

循证医学 2024年第4期24卷 193-200页

作者：吴一龙陆舜程颖周清张嘉涛潘燚汪斌超韩宝惠陈海泉周清华王绿化陈明王洁周彩存刘晓晴马智勇黄诚宋启斌莫树锦钟文昭朱正飞宋勇陈蓉蓉陈克终刘基巍杨帆胡晓桦胡毅杨懿岳东升王群赵军范江陈椿孟庆威闫小龙董晓荣朱波邢力刚李兆澄李子明褚倩陈元林根段建春田攀文范云刘安文刘慧刘哲峰杨农汪步海张同梅信涛刘思阳王志杰马锐于起涛林劼涂海燕姚煜赵明芳王慧娟张海波蔡尚立张绪超李慧杜瀛瀛吴芳严令华崔久嵬王燕邬麟周建娅汪笑男黄媚娟冯卫能周进李力中国抗癌协会肺癌专业委员会广东省临床试验协会/中国胸部肿瘤研究协作组广东省肺癌研究所南方医科大学附属广东省人民医院(广东省医学科学院)广州510080 上海交通大学医学院附属胸科医院上海200030 吉林省肿瘤医院长春130021 复旦大学附属肿瘤医院上海200032 四川大学华西医院成都610041 中国医学科学院肿瘤医院深圳医院广东深圳518116 中山大学肿瘤防治中心广州510060 中国医学科学院肿瘤医院北京100021 同济大学附属上海市肺科医院上海200433 解放军总医院第五医学中心北京100039 郑州大学附属肿瘤医院/河南省肿瘤医院郑州450003 福建省肿瘤医院福州350011 武汉大学人民医院肿瘤中心武汉430060 香港中文大学医学院中国香港东部战区总医院南京210002 北京吉因加科技有限公司北京102206 北京大学人民医院北京100044 大连医科大学附属第一医院辽宁大连116011 广西医科大学第一附属医院南宁530020 解放军总医院北京100071 成都市第三人民医院/西南交通大学医学院成都610031 天津医科大学肿瘤医院天津300060 复旦大学附属中山医院上海200032 北京大学肿瘤医院北京100142 上海交通大学附属上海市第一人民医院上海200025 福建医科大学附属协和医院福州350001 哈尔滨医科大学附属肿瘤医院哈尔滨150081 空军军医大学唐都医院西安710038 华中科技大学同济医学院附属协和医院武汉430022 陆军军医大学第二附属医院-新桥医院重庆400037 山东省肿瘤医院济南250117 华中科技大学同济医学院附属同济医院武汉430030 中国医学科学院肿瘤医院山西医院太原030013 中国科学院大学附属肿瘤医院/浙江省肿瘤医院杭州310022 南昌大学附属第二医院南昌330006 湖南省第二人民医院长沙410035 南京大学医学院附属苏北人民医院江苏扬州225001 首都医科大学附属北京胸科医院北京101149 哈尔滨医科大学附属第二医院哈尔滨150001 暨南大学附属第一医院广州510630 辽宁省肿瘤医院沈阳110042 广西医科大学附属肿瘤医院南宁530012 昆明医科大学第二附属医院昆明650101 西安交通大学第一附属医院西安710061 中国医科大学附属第一医院沈阳110001 广东省中医院广州510120 广州燃石医学检验所有限公司广州510300 安徽医科大学第一附属医院合肥230022 中南大学湘雅二医院长沙410011 上海桐树生物科技有限公司上海200444 吉林大学白求恩第一医院长春130021 湖南省肿瘤医院长沙410013 浙江大学医学院附属第一医院杭州310031 南京世和基因生物技术股份有限公司南京210032 佛山市第一人民医院广东佛山528000 四川省肿瘤医院成都610042 陆军军医大学大坪医院重庆400042 不详

由中国抗癌协会肺癌专业委员会和广东省临床试验协会/中国胸部肿瘤研究协作组主办的“第21届中国肺癌高峰论坛”于2024年3月2日在广州顺利召开。此次论坛以肺癌适应性治疗为主题,从肺癌适应性治疗定义、早中晚期临床应用以及生物标志物... 详细信息

由中国抗癌协会肺癌专业委员会和广东省临床试验协会/中国胸部肿瘤研究协作组主办的“第21届中国肺癌高峰论坛”于2024年3月2日在广州顺利召开。此次论坛以肺癌适应性治疗为主题,从肺癌适应性治疗定义、早中晚期临床应用以及生物标志物对适应性治疗的指导价值等角度展开探讨并达成了专家共识。

关键词：肺癌适应性治疗共识

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我国八个大中城市院前急救流行病学调查分析

中华急诊医学杂志 2010年第11期19卷 1130-1136页

作者：张在其骆福添陈兵陈锋公保才旦黄力柯俊赖欣李继良李金年林才经刘向陆家韬孟庆华宁哗裴雅春孙文会熊悦安张斌赵兴吉欧阳文伟陈文标陈玮莹郭彦池杨正飞黄子通中山大学附属第二医院急诊科广州510120 中山大学公共卫生学院建省急救中心广州市急救医疗指挥中心海口市120急救中心青海省医疗紧急救援中心天津市急救中心武汉市急救中心重庆市急救医疗中心中山市急救中心

目的调查我国大中城市院前急救患者流行病学情况,探讨院前急救病例特点.方法从我国8个大中城市急救中心系统数据库中导出2008年度全部数据,就其有完整记录的资料进行统计分析.结果（1）院前急救组调度时间、到达时间、现场时间、返... 详细信息

目的调查我国大中城市院前急救患者流行病学情况,探讨院前急救病例特点.方法从我国8个大中城市急救中心系统数据库中导出2008年度全部数据,就其有完整记录的资料进行统计分析.结果（1）院前急救组调度时间、到达时间、现场时间、返回时间、出车总时间、急救半径分别为（2.16±1.10）min,（14.01±6.82）min,（12.12±5.96）min,（14.08±6.85）min,（42.34±20.21）min和（8.50±4.18）km,院前非死亡组分别为（2.19±1.13）min,（14.15±7.14）min,（11.60±6.72）min,（14.92±6.89）min,（41.86±19.53）min和（8.63±4.31）km,院前死亡组分别为（2.10±1.08）min,（13.68±7.14）min,（25.25±12.34）min,（13.75±6.48）min,（54.74±25.47）min和（7.86±3.91）km,院前非心脏性猝死组分别为（2.09±1.03）min,（13.58±6.78）min,（25.53±12.34）min,（13.60±6.54）min,（53.79±23.77）min和（7.67±3.86）km,院前心脏性猝死组分别为（2.12±1.02）min,（14.10±7.05）min,（24.79±12.08）min,（13.79±6.61）min,（54.80±25.36）min和（7.90±3.92）km.院前死亡组的调度时间、到达时间、返回时间、急救半径均明显小于院前非死亡组,前组的现场时间、出车总时间均明显大于后者（P＜0.05或P＜0.01）.院前心脏性猝死组的调度时间、返回时间与院前非心脏性猝死组的差异无统计学意义（P＞0.05）,但前组的到达时间、出车总时间、急救半径均明显大于后组,而现场时间明显小于后组（P＜0.05或P＜0.01）.（2）院前急救组、院前非死亡组、院前死亡组、院前非心脏性猝死组、院前心脏性猝死组的病例数均以第一季度为最多,其最少时间段分别是4：00-6：00、4：00-6：00、4：00-6：00、22：00-24：00、2：00-4：00,其最多时间段分别是20：00-22：00、20：00-22：00、8：00-10：00、2：00-4：00、8：00-10：00.（3）在241 876例院前急救病例中,创伤类患者是院前急救中最多的,年龄以21～50岁青壮年最多;其余依次是神经系统、循环系统、其他、消化系统、呼吸系统、中毒类,且神经系统、循环系统、呼吸系统类均以51岁（尤其是70岁）以上的中老年最多;其他、消化系统类均有两个高峰年龄段,其一是21～30岁青年阶段,其二是70岁以上的老年;中毒类以21～50岁青壮年最多,其中急性酒精中毒是最常见的病因.（4）在12 568例院前死亡病例中,循环系统、其他、呼吸系统、神经系统、消化系统类的死亡分别居第一、二、四、五、八位,均以51岁（尤其是70岁）以上的中老年最多,其中心脏性猝死又是循环系统类的死亡中最多的;创伤、中毒类的死亡分别居第三、六位,均以21～50岁青壮年最多.（5）男性患者院前急救的数量、总死亡量及院前心脏性猝死均明显高于女性.（6）院前死亡患者占院前急救的5.20%,院前心脏性猝死占院前急救的1.29%,院前心脏性猝死占院前死亡的24.87%,院前心脏性猝死占循环系统类死亡的67.33%.结论（1）创伤与心脏性猝死已分别成为我国大中城市最常见的院前急救和致死原因.（2）加强心脑血管病和呼吸系统疾病防治,提高中老年患者的常见急危重症早期识别与院前急救水平对降低死亡率有重要意义.（3）加强安全生产、遵守交通法规、强化法制意识将是降低创伤,尤其是交通意外伤发生及其死亡的有力手段.

关键词：院前急救院前死亡心脏性猝死流行病学分析大中城市创伤神经系统循环系统消化系统呼吸系统中毒

我国大中城市院前死亡患者流行病学调查分析——附12568例分析

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新医学 2010年第11期41卷 708-711,770,F0003页

作者：张在其骆福添陈兵陈锋公保才旦黄力柯俊赖欣李继良李金年林才经刘向陆家韬孟庆华宁哗裴雅春孙文会熊悦安张斌赵兴吉欧阳文伟陈文标陈玮莹郭彦池杨正飞黄子通中山大学附属第二医院急诊科 510120 中山大学公共卫生学院 510080 福建省急救中心 350002 青海省医疗紧急救援中心 810007 广州市急救医疗指挥中心 510060 武汉市急救中心 430022 天津市急救中心 300041 海口市120急救中心 570208 中山市急救中心 528403 重庆市急救医疗中心 400014

目的：调查中国大中城市院前死亡患者流行病学情况,探讨院前死亡病例特点.方法：从中国8个大中城市急救中心系统数据库中导出2008年度全部死亡数据,对有完整记录的资料进行统计分析.结果：①12 568例院前死亡者调度时间、到达时间、现... 详细信息

目的：调查中国大中城市院前死亡患者流行病学情况,探讨院前死亡病例特点.方法：从中国8个大中城市急救中心系统数据库中导出2008年度全部死亡数据,对有完整记录的资料进行统计分析.结果：①12 568例院前死亡者调度时间、到达时间、现场时间、返回时间、总时间、急救半径分别为（2.10±1.08） min、（13.68±7.14） min、（25.25±12.34） min、（13.75±6.48） min、（54.74±25.47） min、（7.86±3.91） km;院前非心脏性猝死组分别为（2.09±1.03） min、（13.58±6.78） min、（25.53±12.34） min、（13.60±6.54） min、（53.79±23.77） min、（7.67±3.86） km,院前心脏性猝死组分别为（2.12±1.02） min、（14.10±7.05） min、（24.79±12.08） min、（13.79±6.61） min、（54.80±25.36） min、（7.90±3.92） km.院前非心脏性猝死组与院前心脏性猝死组到达时间、现场时间、出车总时间、急救半径比较差异均有统计学意义（P〈0.05或0.01）.②院前死亡总体、院前非心脏性猝死组、院前心脏性猝死组的病例数月份及季节分布以2月份、第一季度为最多,日时间段分布以8：00～10：00为最多.③院前死亡患者中循环系统、其他、呼吸系统、神经系统、消化系统类的死亡数分别位居第一、二、四、五、八,均以51岁（尤其是70岁）以上的中老年阶段最多,其中循环系统类中心脏性猝死死亡最多;创伤、中毒类的死亡分别位居第三、六,均以21～50岁青壮年阶段最多.④男性院前死亡数及院前心脏性猝死数均明显多于女性.⑤院前心脏性猝死占循环系统类死亡的绝大部分（67.33%）,目击者现场心肺复苏（CPR）为4.46%,医护人员现场CPR成功率2.21%.结论：①心脏性猝死是中国大中城市最常见的院前死亡原因.②加强心脑血管疾病和呼吸系统疾病防治,提高中老年患者的常见急危重症早期识别与院前急救水平以及普及公众CPR对降低死亡有重要意义.③创伤致死是中国大中城市又一常见院前死因,加强安全生产、遵守交通法规、强化法制意识将是降低创伤,尤其是交通意外伤发生及其死亡的有力手段.

关键词：院前急救院前死亡心脏性猝死流行病学分析

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非小细胞肺癌少见/罕见靶点:共识与争鸣

循证医学 2023年第3期23卷 129-139页

作者：吴一龙陆舜程颖周清涂海燕周清华王绿化张力周建英黄诚陈明胡成平揣少坤汪笑男刘晓晴刘基巍周鹏辉陈维之严令华刘云鹏刘安文张绪超李慧陈蓉蓉林冬梅谢聪颖朱正飞梁会营宋勇董晓荣赵明芳乔贵宾崔久嵬李子明王志杰陈晓媛杨农林根田攀文范云宋启斌陈元段建春王佳蕾朱波汪步海赵军于起涛王立峰张海波胡洁马锐张同梅林劼褚倩任胜祥姚煜邬麟王慧娟吴芳钟文昭胡毅陈克能赵健张力杨帆王群岳东升周建娅申鹏张嘉涛闫小龙黄媚娟冯卫能李力中国抗癌协会肺癌专业委员会广东省临床试验协会/中国胸部肿瘤研究协作组不详广东省肺癌研究所南方医科大学附属广东省人民医院(广东省医学科学院)广州510080 上海交通大学附属胸科医院上海200030 吉林省肿瘤医院长春130021 四川大学华西医院成都610041 中国医学科学院肿瘤医院深圳医院广东深圳518116 中山大学肿瘤防治中心广州510060 浙江大学医学院附属第一医院杭州310031 福建省肿瘤医院福州350011 中南大学湘雅医院长沙410008 广州燃石医学检验所有限公司广州510300 南京世和基因生物技术股份有限公司南京210032 解放军总医院北京100071 大连医科大学附属第一医院辽宁大连116011 无锡臻和生物科技有限公司江苏无锡214105 上海桐树生物科技有限公司上海200444 中国医科大学附属第一医院沈阳110001 南昌大学附属第二医院南昌330006 北京吉因加科技有限公司北京102206 北京大学肿瘤医院北京100142 温州医科大学附属第二医院浙江温州325027 复旦大学附属肿瘤医院上海200032 东部战区总医院南京210002 华中科技大学同济医学院附属协和医院武汉430022 吉林大学白求恩第一医院长春130021 中国医学科学院肿瘤医院北京100021 清华大学医学院北京100084 湖南省肿瘤医院长沙410013 中国科学院大学附属肿瘤医院/浙江省肿瘤医院杭州310022 武汉大学人民医院肿瘤中心武汉430060 华中科技大学同济医学院附属同济医院武汉430030 陆军军医大学第二附属医院-新桥医院重庆400037 南京大学医学院附属苏北人民医院江苏扬州225001 广西医科大学附属肿瘤医院南宁530012 南京大学医学院附属鼓楼医院南京210008 广东省中医院广州510120 复旦大学附属中山医院上海200032 辽宁省肿瘤医院沈阳110042 首都医科大学附属北京胸科医院北京101149 昆明医科大学第二附属医院昆明650101 同济大学附属上海市肺科医院上海200433 西安交通大学第一附属医院西安710061 郑州大学附属肿瘤医院/河南省肿瘤医院郑州450003 中南大学湘雅二医院长沙410011 广州医科大学附属肿瘤医院广州510095 北京协和医院北京100032 北京大学人民医院北京100044 天津医科大学肿瘤医院天津300060 南方医科大学南方医院广州510515 空军军医大学唐都医院西安710038 佛山市第一人民医院广东佛山528000 陆军军医大学大坪医院重庆400042

由中国抗癌协会肺癌专业委员会和广东省临床试验协会/中国胸部肿瘤研究协作组主办的“第20届中国肺癌高峰论坛”于2023年3月4日在广州顺利召开。此次论坛以非小细胞肺癌(non-small cell lung cancer,NSCLC)少见/罕见靶点为主题,从少见/... 详细信息

由中国抗癌协会肺癌专业委员会和广东省临床试验协会/中国胸部肿瘤研究协作组主办的“第20届中国肺癌高峰论坛”于2023年3月4日在广州顺利召开。此次论坛以非小细胞肺癌(non-small cell lung cancer,NSCLC)少见/罕见靶点为主题,从少见/罕见靶点的精准检测、新型临床研究与围术期治疗等角度开展相关学术探讨,并最终达成了专家共识。

关键词：非小细胞肺癌少见/罕见靶点共识争鸣