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Science Bulletin 2018年第11期63卷 672-674页

作者： feng gu School of Ophthalmology and Optometry Eye Hospital Wenzhou Medical University State Key Laboratory Cultivation Base and Key Laboratory of Vision Science Ministry of Health and Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry

CRISPR-Cas systems has been developed as genome editing tools,which are originally discovered as sequence-specific defense system utilized by bacteria and archaea to fight with the invasion by foreign nucleic acids such as phages or *** to the current classification groups of CRISPR-Cas system,Type I,Type III and Type IV comprise the Class 1 systems for their function through multisubunit Cas protein complex to interference the targeted nucleic *** contrast,Class 2 systems,consisting of

关键词：编辑工具染色体葡萄球菌结构防卫系统噬菌体

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Analysis of Allele Specific Expression——A Survey

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Tsinghua Science and Technology 2015年第5期20卷 513-529页

作者： feng gu Xue Wang the Department of Computer Science The College of Staten IslandThe City University of New York Mayo Clinic 4500 San Pablo RoadJacksonville FL 32224 USA

Allele specific expression is essential for cellular programming and development and the diversity of cellular phenotypes. Traditional analysis methods utilize RNA and depend on single nucleotide polymorphisms,thus to suffer from limited amount of materials for analysis. The rapid development of next-generation sequencing technologies provides more comprehensive and powerful approaches to analyze the genomic, epigenetic, and transcriptomic data, and further to detect and measure allele specific expressions. It will potentially enhance the understanding of the allele specific expressions, their complexities, and the effect on biological processes. In this paper, we extensively review the state-of-art enabling technologies and tools to analyze, detect, and measure allele specific expressions, compare their features, and point out the future trend of the methods.

关键词： allele specific expression cellular phenotypes sequencing technologies Single Nucleotide Polymorphism(SNP) Single Nucleotide Variant(SNV) statistical methods transcripts

Theoretical analysis of cross-plane lattice thermal conduction in graphite

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Chinese Physics B 2019年第6期28卷 317-323页

作者： Yun-feng gu College of Electronic and Mechanical Engineering Nanjing Forestry University

A theoretical analysis of the cross-plane lattice thermal conduction in graphite is performed by using first-principles calculations and in the single-mode relaxation time approximation. The out-of-plane phonon acoustic mode ZA and optical mode ZO have almost 80% and 20% of contributions to cross-plane heat transfer, respectively. However, these two branches have a small part of total specific heat above 300 K. Phonons in the central 16% of Brillouin zone contribute80% of cross-plane transport. If the group velocity angle with respect to the graphite layer normal is less than 30?, then the contribution is 50% at 300 K. The ZA phonons with long cross-plane mean free path are focused in the cross-plane direction, and the largest mean free path is on the order of several micrometers at room temperature. The average value of cross-plane mean free path at 300 K is 112 nm for ZA phonons with group velocity angle with respect to the layer normal being less than 15?. The average value is dropped to 15 nm when phonons of all branches in the whole Brillouin zone are taken into account, which happens because most phonons have small or even no contributions.

关键词： graphite cross-plane thermal conduction phonon mean free path layered systems

A new iterative process for approximating common fixed points of nonself I-asymptotically quasi-nonexpansive mappings

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Applied Mathematics(A Journal of Chinese Universities) 2012年第4期27卷 489-502页

作者： Isa Yildirim feng gu Department of Mathematics Faculty of ScienceAtaturk UniversityErzurum 25240Turkey Institute of Applied Mathematics Department of MathematicsHangzhou Normal UniversityHangzhou 310036China

In this paper, we introduce an iterative process for two nonself I-asymptotically quasi-nonexpansive mappings and two finite families of such mappings in Banach spaces, and prove some strong convergence theorems for s... 详细信息

关键词： nonseIf I-asymptoticaliy quasi-nonexpansive mapping common fixed point uniformly convexBanach space.

The composite X-ray spectra of radio-loud and radio-quiet SDSS quasars

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Research in Astronomy and Astrophysics 2021年第1期21卷 33-44页

作者： Min-Hua Zhou Min-feng gu Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy ofSciences80 Nandan RoadShanghai 200030China University of Chinese Academy of Sciences 19A Yuquan RoadBeijing 100049China

We present a study of the X-ray emission for a sample of radio-detected quasars constructed from the cross-matches between SDSS,FIRST catalogs and XMM-Newton archives.A sample of radio-quiet SDSS quasars without FIRST radio detection is also assembled for *** construct the optical and X-ray composite spectra normalized at rest frame 4215 A(or 2200 A)for both radio-loud quasars(RLQs)and radio-quiet quasars(RQQs)at z≤3.2,with matched X-ray completeness of 19%,redshift and optical *** the optical composite spectrum of RLQs is similar to that of RQQs,we find that RLQs have a higher X-ray composite spectrum than RQQs,consistent with previous studies in the *** dividing the radio-detected quasars into radio loudness bins,we find the X-ray composite spectra are generally higher with increasing radio ***,a significant correlation is found between the optical-to-X-ray spectral index and radio loudness,and there is a unified multi-correlation between the radio and X-ray luminosities and radio loudness in radio-detected *** results could be possibly explained with the corona-jet model,in which the corona and jet are directly related.

关键词： methods:statistical catalogs quasars:general X-rays:general

Thermal stability improvement of sprayable fast-responding pressure-sensitive paint for measurement above 100℃

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Chinese Journal of Aeronautics 2021年第1期34卷 320-326页

作者： Di PENG feng gu Zhe ZHONG Yingzheng LIU Key Lab of Education Ministry for Power Machinery and Engineering School of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240China Gas Turbine Research Institute Shanghai Jiao Tong UniversityShanghai 200240China

The thermal stability of sprayable fast-responding Pressure-Sensitive Paint(fast PSP)was investigated to explore the possibility for application in turbomachinery and hypersonic research with temperature above 100℃.The first part of the study focused on a widely-used Polymer Ceramic PSP(PC-PSP).The effects of thermal degradation on its key sensing properties,including luminescent intensity,pressure sensitivity and response time,were examined for a temperature range from 60 to 100℃.Severe degradation in intensity and pressure sensitivity was found as temperature reached 70℃or higher,which would cause failure of PSP application in these ***,a fast-responding Mesoporous-Particle PSP(MP-PSP)was developed which did not show degradation effects until 140℃.The greatly improved thermal stability of MP-PSP was attributed to:selection of polymer with higher glass transition temperature(polystyrene)to delay the saturation effect of oxygen quenching as temperature increased;porous and hollow structure of particles for luminophore deposition that minimizes polymer–luminophore *** new paint formulation has significantly raised the upper temperature limit of fast PSP and offers more opportunities for applications in harsh environment.

关键词： Dynamic response Polymer–luminophore interaction Pressure sensitivity Pressure-sensitive paint Thermal degradation

Implementation of Envelope Analysis on a Wireless Condition Monitoring System for Bearing Fault Diagnosis

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International Journal of Automation and computing 2015年第1期12卷 14-24页

作者： guo-Jin feng James gu Dong Zhen Mustafa Aliwan feng-Shou gu Andrew D.Ball School of Computing and Engineering University of Huddersfield School of Engineering Manchester Metropolitan University

Envelope analysis is an effective method for characterizing impulsive vibrations in wired condition monitoring(CM)systems. This paper depicts the implementation of envelope analysis on a wireless sensor node for obtaining a more convenient and reliable CM system. To maintain CM performances under the constraints of resources available in the cost effective Zigbee based wireless sensor network(WSN), a low cost cortex-M4 F microcontroller is employed as the core processor to implement the envelope analysis algorithm on the sensor node. The on-chip 12 bit analog-to-digital converter(ADC) working at 10 k Hz sampling rate is adopted to acquire vibration signals measured by a wide frequency band piezoelectric accelerometer. The data processing flow inside the processor is optimized to satisfy the large memory usage in implementing fast Fourier transform(FFT) and Hilbert transform(HT). Thus, the envelope spectrum can be computed from a data frame of 2048 points to achieve a frequency resolution acceptable for identifying the characteristic frequencies of different bearing faults. Experimental evaluation results show that the embedded envelope analysis algorithm can successfully diagnose the simulated bearing faults and the data transmission throughput can be reduced by at least 95% per frame compared with that of the raw data, allowing a large number of sensor nodes to be deployed in the network for real time monitoring.

关键词： Wireless sensor network(WSN) envelope analysis fault diagnosis local processing Hilbert transformation

A trade-off between space exploration and mobilization of organic phosphorus through associated microbiomes enables niche differentiation of arbuscular mycorrhizal fungi on the same root

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Science China(Life Sciences) 2023年第6期66卷 1426-1439页

作者： Jiachao Zhou Thomas W Kuyper gu feng College of Resources and Environmental Sciences China Agricultural UniversityBeijing100193China Soil Biology Group Wageningen University&ResearchWageningen6700 AAThe Netherlands

Ecology seeks to explain species coexistence,but experimental tests of mechanisms for coexistence are difficult to *** synthesized an arbuscular mycorrhizal(AM)fungal community with three fungal species that differed in their capacity of foraging for orthophosphate(P)due to differences in soil *** tested whether AM fungal species-specific hyphosphere bacterial assemblages recruited by hyphal exudates enabled differentiation among the fungi in the capacity of mobilizing soil organic P(P_(o)).We found that the less efficient space explorer,Gigaspora margarita,obtained less ^(13)C from the plant,whereas it had higher efficiencies in P_(o)mobilization and alkaline phosphatase(Al Pase)production per unit C than the two efficient space explorers,Rhizophagusintraradices and Funneliformis *** AM fungus was associated with a distinct alp gene harboring bacterial assemblage,and the alp gene abundance and P_(o)preference of the microbiome associated with the less efficient space explorer were higher than those of the two other *** conclude that the traits of AM fungal associated bacterial consortia cause niche *** trade-off between foraging ability and the ability to recruit effective P_(o)mobilizing microbiomes is a mechanism that allows co-existence of AM fungal species in a single plant root and surrounding soil habitat.

关键词： arbuscular mycorrhizal fungi carbon space exploration hyphosphere bacterial assemblages organic phosphorus mobilization

Template-free approach for hydrothermal fabrication of ZnO microspheres

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Particuology 2009年第3期7卷 225-228页

作者： Hao Jiang Junqing Hu feng gu Chunzhong Li Key Laboratory for Ultrafine Materials of Ministry of Education School of Materials Science and Engineering East China University of Science & Technology Shanghai 200237 China College of Materials Science and Engineering State Key Laboratory for Modification of Chemical Fibers and Polymer Materials Donghua University Shanghai 200051 China

Wurtzite ZnO microspheres, 5.5-11 μm in diameter and with smooth surfaces, were prepared in absolute ethanol via a simple template-free method in the presence of ethylenediamine. The products were characterized using X-ray powder diffraction, scanning electron microscopy and transmission electron microscopy. This simple method to fabricate ZnO microspheres shows high yield （〉90%） and good reproducibiliry. The formation process of ZnO microspheres was discussed. The as-obtained ZnO microspheres are expected to provide some immediate advantages for optical, microelectronic, and biological applications.

关键词： Zinc oxide Hydrothermal crystal growth Microspheres

Large-scale synthesis of hollow titania spheres via flame combustion

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Particuology 2011年第6期9卷 632-636页

作者： Jie Liu Yanjie Hu feng gu Chunzhong Li Key Laboratory for Ultrafine Materials of Ministry of Education School of Materials Science and Engineering East China University of Science ＆ Technology Shanghai 200237 China

A one-step method for continuous large-scale synthesis of well-defined hollow titania spheres was established by feeding titanium tetrachloride mixed with ethanol vapor to a facile diffusion flame. A mixture of TiCl4 and C2H5OH vapor was transported at 100 m/s into a flame reactor and condensed into mesoscale droplets due to Joule-Thomson cooling and the entrainment of cool gases into the expanding high-speed jet. Hollow crystalline TiO2 spheres with good thermal stability were formed after the hydrolysis of TiCl4 in the H2/air flame at about 1500℃. Structural characterization indicates that the hollow spheres, with uniform diameter of 300 nm and shell thickness of 35 rim, consist of 20-30 nm TiO2 nanocrystallites. A formation mechanism of the hollow spheres was proposed, involving the competition between chemical reaction and diffusion during the flame process. The present study provides a new pathway for continuous and large-scale engineering of hollow nanomaterials.

关键词： Flame combustion Hollow spheres Titania Formation mechanism Large-scale