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Effect of Moxibustion on the Motility, Absorption and Activities of ATPase in Small Intestine of Spleen-deficiency Rats

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Journal of Acupuncture and Tuina Science 2014年第2期12卷 67-72页

作者： peng Yan Yi Shou-xiang peng fen Long Yi-wen Lin Ya-ping Chang Xiao-rong Xu Bin Major Laboratory of Meridians and Viscera Tertiary Laboratory of State Administration of Traditional Chinese MedicineInstitute of AcupunctureMoxibustion and Massage Hunan University of Traditional Chinese Medicine Traditional Chinese Medicine Department of Nanjing University of Chinese Medicine

Objective： To observe the effect of moxibustion on intestinal propulsion rate, content of serum D-xylose, content of adenosine triphosphate （ATP） and activities of adenosine triphosphatases （ATPase） in jejunum tissues of spleen-deficiency rats, and to explore the effect of moxibustion on the production of ATP and activities of membrane proteins, for analyzing the mechanism of moxibustion in reinforcing the spleen-stomach. Methods： Forty healthy Sprague Dawley rats were randomly divided into four groups, namely group A （blank control group）, group B （model control group）, group C （moxibustion group） and group D （herbs group）. The animal model of spleen-deficiency was established by intragastric administration with Da Huang （Radix et Rhizoma Rhei） infusion. The rats in group C received moxibustion at Zusanli （ST 36）, Zhongwan （CV 124 Guanyuan （CV 4）, Pishu （BL 20） and Weishu （BL 21）. The rats in group D received intragastric administration with 5i Jun Zi decoction. The intestinal propulsion was measured by toner method, and the content of D-xylose in serum was detected by phloroglucinol method. Colorimetry method was used to detect the content of ATP and activities of Na^＋-K^＋-ATPase and Ca^2＋-Mg^2＋-ATPase in jejunum tissues. Results： Compared with group A, the intestinal propulsion rate, content of D-xylose in serum, content of ATP, activities of Na^＋-K^＋-ATPase and Ca^2＋-Mg^2＋-ATP in jejunum tissues decreased significantly in group B （P〈0.05 or P〈O.O1）. Compared with group B, the intestinal propulsion rate, content of D-xylose in serum, content of ATP, activities of Na^＋-K^＋-ATPase and Ca^2＋-Mg^2＋-ATPase in jejunum tissues increased significantly in group C and D （P〈0.05 or P〈0.01）, while there were no significant differences between group C and group D. Conclusion： Moxibustion can increase the intestinal propulsion rate, content of D-xylose in serum and ATP in jejunum tissues, as well as the activities of Na^-K＋-ATPase and Ca^2＋-Mg^2＋-ATPase of spleen-deficiency

关键词： Moxibustion Therapy Spleen Deficiency Adenosine Triphosphate (ATP) Adenosine Triphosphatases Rats

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Comparison of outcomes following three surgical techniques for patients with severe jejunoileal atresia

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Gastroenterology Report 2019年第6期7卷 444-448,I0002页

作者： Yan-fen peng Hai-Qing Zheng Hong Zhang Qiu-Ming He Zhe Wang Wei Zhong Jia-Kang Yu Department of Neonatal Surgery Guangzhou Women and Children’s Medical CenterGuangzhouGuangdongP.R.China Institute of Pediatrics Guangzhou Women and Children’s Medical CenterGuangzhouGuangdongP.R.China

Background:Severe jejunoileal atresia is associated with prolonged parenteral nutrition,higher mortality and secondary ***,the ideal surgical management of this condition remains *** study aimed to compare the outcomes of patients with severe jejunoileal atresia treated by three different ***:From January 2007 to December 2016,105 neonates with severe jejunoileal atresia were retrospectively *** these,42 patients(40.0%)underwent the Bishop–Koop procedure(BK group),49(46.7%)underwent primary anastomosis(PA group)and 14(13.3%)underwent Mikulicz double-barreled ileostomy(DB group).Demographics,treatment and outcomes including mortality,morbidity and nutrition status were reviewed and were compared among the three ***:The total mortality rate was 6.7%,showing no statistical difference among the three groups(P=0.164).The BK group had the lowest post-operative complication rate(33.3%vs 65.3%for the PA group and 71.4%for the DB group,P=0.003)and re-operation rate(4.8%vs 38.8%for the PA group and 14.3%for the DB group,P<0.001).Compared with the BK group,the PA group showed a positive correlation with the complication rate and re-operation rate,with an odds ratio of 4.15[95%confidence interval(CI):1.57,10.96]and 12.78(95%CI:2.58,63.29),*** DB group showed a positive correlation with the complication rate when compared with the BK group,with an odds ratio of 7.73(95%CI:1.67,35.72).The weight-for-age Z-score at stoma closure was–1.22(95%CI:–1.91,–0.54)in the BK group and–2.84(95%CI:–4.28,–1.40)in the DB group(P=0.039).Conclusions:The Bishop–Koop procedure for severe jejunoileal atresia had a low complication rate and re-operation rate,and the nutrition status at stoma closure was superior to double-barreled *** Bishop–Koop procedure seems to be an appropriate choice for severe jejunoileal atresia.

关键词： Jejunoileal atresia Bishop–Koop procedure double-barreled ileostomy outcomes

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Decreased Nrf2 protein level and low sperm quality in intractable spermatocystitis

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Asian Journal of Andrology 2024年第2期26卷 189-194页

作者： Shi-Ze Wang Jian-Nan Liu fen-Fang Zhou Ye-Jin-peng Wang peng Zhang Song-Tao Cheng Department of Urology Sichuan Provincial People's HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610072China Department of Urology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Health Management and Clinical Medicine School of Medicine and HealthWuhan PolytechnicUniversityWuhan 430071China

To investigate the molecular etiology of low sperm quality in patients with intractable spermatocystitis,spermatozoa samples from patients with persistent hematospermia undergoing transurethral seminal vesiculoscopy and healthy volunteers were *** samples were collected from the seminal vesicles through transurethral seminal vesiculoscopy or by masturbation *** quality was analyzed by a WLJY-9000 color semen analysis *** of tumor necrosis factor alpha(TNFa)and interleukin-6(IL-6)in the seminal plasma was performed using enzyme-linked immunosorbent assay(ELISA).Measurement of H_(2)O_(2)in the seminal plasma was performed with a hydrogen peroxide *** protein levels of nuclear factor erythroid 2-related factor 2(Nrf2)and phosphorylated-Nrf2(p-Nrf2)were measured by western blot analysis and immunofluorescence *** sperm quality parameters and increased levels of inflammatory cytokines(TNFa,IL-6,and H_(2)O_(2))in the seminal plasma were detected among the semen samples from the patients with persistent ***2 and p-Nrf2 were strongly expressed in the nucleus and periphery of human sperm cells,according to the results of the immunofluorescence *** protein levels of Nrf2 and p-Nrf2 were significantly lower in the spermatozoa samples from patients with persistent hematospermia than in those from healthy volunteers with normal sperm *** results suggested that Nrf2 signaling might play a role in the low sperm quality of patients with intractable spermatocystitis.

关键词： H_(2)O_(2) Nrf2 sperm quality spermatocystitis

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Henna Tattoo： Temporary or Permanent？

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Chinese Medical Journal 2017年第22期130卷 2769-2770页

作者： fen peng Juan Du Chen-Hong Xue Shuo-Shuo Liu Wen-Hai Li Zhou Chen Jian-Zhong Zhang Department of Dermatology Peking University People's Hospital Beijing 100044 China

To the Editor： Henna tattoo has become popular and is increasingly reported as a cause of allergic skin reactions. Three cases of contact dermatitis caused by henna tattoos in China have been described.

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Perineuronal nets increase inhibitory GABAergic currents during the critical period in rats

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International Journal of Ophthalmology(English edition) 2013年第2期6卷 120-125页

作者： Hui Liu peng-fen Gao Hai-Wei Xu Ming-Ming Liu Tao Yu Jun-Ping Yao Zheng-Qin Yin Southwest Eye Hospital Southwest Hospital Third Military Medical University Key Lab of Visual Damage and Regeneration & Restoration of Chongqing

AIM: To investigate inhibitory γ-aminobutyric acid (GABA) ergic postsynaptic currents (IPSCs) and postsynaptic currents (PSCs) in layer IV of the rat visual cortex during the critical period and when plasticity was extended through dissolution of the perineuronal nets (PNNs). METHODS: We employed 24 normal Long-Evans rats to study GABA A-PSC characteristics of neurons within layer IV of the visual cortex during development. The animals were divided into six groups of four rats according to ages at recording: PW3 (P21 -23d), PW4 (P28 -30d), PW5 (P35-37d), PW6 (P42-44d), PW7 (P49-51d), and PW8 (56-58d). An additional 24 chondroitin sulfate proteoglycan (CSPG) degradation rats (also Long-Evans) were generated by making a pattern of injections of chondroitinase ABC (chABC) into the visual cortex 1 week prior to recording at PW3, PW4, PW5, PW6, PW7, and PW8. Immunohistochemistry was used to identify the effect of chABC injection on CSPGs. PSCs were detected with whole-cell patch recordings, and GABA A receptor-mediated IPSCs were pharmacologically isolated. RESULTS: IPSC peak current showed a strong rise in the age-matched control group, peaked at PW5 and were maintained at a roughly constant value thereafter. Although there was a small increase in peak current for the chABC group with age, the peak currents continued to decrease with the delayed highest value at PW6, resulting in significantly different week-by-week com-parison with normal development. IPSC decay time continued to increase until PW7 in the control group, while those in the chABC group were maintained at astable level after an initial increase at PW4. Compared with normal rats, the decay times recorded in the chABC rats were always shorter, which differed significantly at each age. We did not observe any differences in IPSC properties between the age-matched control and penicillinase (P-ase) group. However, the change in IPSCs after chABC treatment was not reflected in the total PSCs or in basic membrane

关键词： gamma-aminobutyric acid receptor plasticity visual cortex development postsynaptic currents chondroitinase ABC chondroitin sulfate proteoglycans whole-cell patch recording

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血清CyPA、sCLU、HO-1与新生儿窒息复苏后发生脑损伤的关系研究

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现代生物医学进展 2024年第6期24卷 1150-1154,1134页

作者：向垚林吴素英刘兆敏方超策周玉彭芬湖北民族大学附属民大医院新生儿科湖北恩施445000

目的:探讨血清亲环素A(CyPA)、丛生蛋白(sCLU)、血红素氧化酶-1(HO-1)与新生儿窒息复苏后发生脑损伤的关系。方法:选择2020年6月至2023年3月湖北民族大学附属民大医院收治的172例窒息新生儿,根据复苏后是否发生脑损伤分为脑损伤组(80例... 详细信息

目的:探讨血清亲环素A(CyPA)、丛生蛋白(sCLU)、血红素氧化酶-1(HO-1)与新生儿窒息复苏后发生脑损伤的关系。方法:选择2020年6月至2023年3月湖北民族大学附属民大医院收治的172例窒息新生儿,根据复苏后是否发生脑损伤分为脑损伤组(80例)和无脑损伤组(92例),复苏治疗前检测并对比两组血清CyPA、sCLU、HO-1水平。多因素Logistic回归分析新生儿窒息复苏后发生脑损伤的影响因素,受试者工作特征(ROC)曲线分析血清CyPA、sCLU、HO-1预测新生儿窒息复苏后发生脑损伤的价值。结果:脑损伤组血清CyPA、sCLU、HO-1水平高于无脑损伤组(P<0.05)。胎盘早剥、母体妊娠高血压疾病、重度窒息、高水平CyPA、高水平sCLU、高水平HO-1是新生儿窒息复苏后发生脑损伤的危险因素(P<0.05)。血清CyPA、sCLU、HO-1预测新生儿窒息复苏后发生脑损伤的曲线下面积为0.797、0.832、0.779,联合预测的曲线下面积为0.941,高于各指标单独预测。结论:新生儿窒息复苏后发生脑损伤的危险因素包括胎盘早剥、母体妊娠高血压疾病、重度窒息、CyPA升高、sCLU升高、HO-1升高,联合检测血清CyPA、sCLU和HO-1对新生儿窒息复苏后发生脑损伤具有较高的预测价值。

关键词：新生儿窒息脑损伤 CyPA sCLU HO-1 预测价值

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Cu-Co负载量对Cu-Co基催化剂催化CH_4-合成气梯阶转化合成C_2^+含氧化合物的影响

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高等学校化学学报 2013年第11期34卷 2587-2593页

作者：彭芬黄伟韩涛太原理工大学煤科学与技术教育部和山西省重点实验室太原030024

以TiO2纳米粒子为载体,采用等体积浸渍法制备了Cu-Co双金属催化剂,考察了不同Cu/Co质量比和不同Cu-Co含量的双金属催化剂对CH4-合成气梯阶转化直接合成C+2含氧化合物的影响.在连续式步阶固定床反应装置上进行了催化性能评价.实验结果表... 详细信息

以TiO2纳米粒子为载体,采用等体积浸渍法制备了Cu-Co双金属催化剂,考察了不同Cu/Co质量比和不同Cu-Co含量的双金属催化剂对CH4-合成气梯阶转化直接合成C+2含氧化合物的影响.在连续式步阶固定床反应装置上进行了催化性能评价.实验结果表明,当Cu-Co含量为18%,Cu/Co质量比为2∶1时,CuCo/TiO2的C+2含氧化合物产物的时空收率最大,为19.92 mg·g-1cat·h-1,选择性为67.76%.研究表明,金属组分之间和载体与金属组分之间的相互作用、金属组分良好的分散性和还原性是促进活性位的形成和提高催化剂活性的原因;催化剂表面高度分散的CuO微晶有利于催化加氢和脱氢反应的进行,对CH4-合成气转化反应有重要的促进作用.另外,弱酸和中强酸有利于CH4-合成气转化反应,而强酸对该反应有抑制作用.

关键词： Cu-Co催化剂 CH4-合成气梯阶转化

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达格列净治疗慢性心力衰竭的疗效及对患者心功能与血清炎性因子水平的影响

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海南医学 2024年第12期35卷 1694-1698页

作者：陈静茹张淑娟赵庆彦冯高科彭芬刘平武汉大学人民医院心内科&武汉大学心血管病研究所&心血管病湖北省重点实验室湖北武汉430060

目的观察达格列净片治疗慢性心力衰竭(CHF)的疗效,并探讨其对患者心功能与血清炎性因子水平的影响。方法选取2020年3月至2021年6月武汉大学人民医院心血管内科收治的120例非糖尿病CHF患者为研究对象,按随机数表法分为对照组与观察组各6... 详细信息

目的观察达格列净片治疗慢性心力衰竭(CHF)的疗效,并探讨其对患者心功能与血清炎性因子水平的影响。方法选取2020年3月至2021年6月武汉大学人民医院心血管内科收治的120例非糖尿病CHF患者为研究对象,按随机数表法分为对照组与观察组各60例。两组患者均采用常规抗CHF治疗方法,观察组在此基础上加用达格列净片治疗,疗程为6个月。比较两组患者的治疗效果,以及治疗前后的心功能指标[左心室射血分数(LVEF)、左心室收缩末期内径(LVESD)、舒张早期二尖瓣血流峰值速度和舒张早期二尖瓣环峰值速度值(E/e')]、心肌损伤标志物[可溶性生长刺激表达基因2蛋白(sST2)、N末端脑钠肽前体(NT-proBNP)]、血清炎性因子[基质金属蛋白酶9(MMP-9)、肿瘤坏死因子-α(TNF-α)、白介素6(IL-6)]水平,同时比较两组患者治疗期间的不良反应发生情况。结果观察组患者的治疗总有效率为88.33%,明显高于对照组的75.00%,差异具有统计学意义(P0.05)。结论达格列净片治疗非糖尿病的CHF可改善患者心功能,减少心肌损伤、降低血清炎性因子水平,临床疗效确切且不良反应少。

关键词：慢性心力衰竭达格列净疗效心功能炎性因子

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用生命演绎“自我与历史的戏剧”——美国现代思想家尼布尔思想综述

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世界哲学 2008年第2期 109-112页

作者：彭芬中国社会科学院研究生院

莱茵霍尔德·尼布尔是美国20世纪的神学政治哲学家。他的大量著述在当今的神学、伦理学、政治哲学等领域产生了很大的影响。对于这个人,国内学界关注较少,本文旨在对尼布尔的思想历程进行概要的介绍。

关键词：道德的人与不道德的社会基督教现实主义道德自由主义光明之子与黑暗之子

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改进卷积神经网络的舰船物联网安全风险估计

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舰船科学技术 2021年第14期43卷 205-207页

作者：彭芬武汉职业技术学院电子信息工程学院

现有方法在舰船物联网威胁识别率与缺陷识别率上表现不佳,因此提出一种改进卷积神经网络的舰船物联网安全风险估计方法。对舰船物联网安全风险数据进行分类也就是分类安全风险指标。对于动态类安全风险数据,需要对其进行数据补充。运行... 详细信息

现有方法在舰船物联网威胁识别率与缺陷识别率上表现不佳,因此提出一种改进卷积神经网络的舰船物联网安全风险估计方法。对舰船物联网安全风险数据进行分类也就是分类安全风险指标。对于动态类安全风险数据,需要对其进行数据补充。运行类安全风险数据的预处理需要进行数据清理。基础类安全风险数据的预处理需要进行数据变换与数据归一化处理。基于改进卷积神经网络提取舰船物联网安全风险数据特征,使用的改进卷积神经网络为SSD神经网络。基于灰色层次分析、Borda序列、风险矩阵构建舰船物联网安全风险估计模型。对设计方法进行实践应用,测试其舰船物联网威胁识别率与缺陷识别率,结果表明该方法取得了识别率数据上的突破,能够保障舰船物联网的安全。

关键词：改进卷积神经网络回归分析舰船物联网数据变换安全风险估计

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