检索结果-南通市图书馆

A drug-loaded flexible substrate improves the performance of conformal cortical electrodes

Bio-Design and Manufacturing 2024年第4期7卷 399-412页

作者： Rongrong Qin Tian Li Yifu Tan fanqi sun Yuhao Zhou Ronghao Lv Xiaoli You Bowen Ji Peng Li Wei Huang Frontiers Science Center for Flexible Electronics(FSCFE) Xi’an Institute of Flexible Electronics(IFE)and Xi’an Institute of Biomedical Materials&Engineering(IBME)Northwestern Polytechnical UniversityXi’an 710072China Unmanned System Research Institute Northwestern Polytechnical UniversityXi’an 710072China Ministry of Education Key Laboratory of Micro and Nano Systems for Aerospace School of Mechanical EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Key Laboratory of Flexible Electronics of Zhejiang Province Ningbo Institute of Northwestern Polytechnical UniversityNingbo 315103China

Cortical electrodes are a powerful tool for the stimulation and/or recording of electrical activity in the nervous ***,the inevitable wound caused by surgical implantation of electrodes presents bacterial infection and inflammatory reaction risks associated with foreign body ***,inflammation of the wound area can dramatically worsen in response to bacterial *** consequences can not only lead to the failure of cortical electrode implantation but also threaten the lives of ***,we prepared a hydrogel made of bacterial cellulose(BC),a flexible substrate for cortical electrodes,and further loaded antibiotic tetracycline(TC)and the anti-inflammatory drug dexamethasone(DEX)onto *** encapsulated drugs can be released from the BC hydrogel and effectively inhibit the growth of Gram-negative and Gram-positive ***,therapeutic cortical electrodes were developed by integrating the drug-loaded BC hydrogel and nine-channel serpentine arrays;these were used to record electrocorticography(ECoG)signals in a rat *** to the controlled release of TC and DEX from the BC hydrogel substrate,therapeutic cortical electrodes can alleviate or prevent symptoms associated with the bacterial infection and inflammation of brain *** approach facilitates the development of drug delivery electrodes for resolving complications caused by implantable electrodes.

关键词： Antibacterial Anti-inflammatory Drug loading Cortical electrodes Bacterial cellulose hydrogel

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Brainmask:an ultrasoft and moist microelectrocorticography electrode for accurate positioning and long-lasting recordings

引用

Microsystems & Nanoengineering 2023年第5期9卷 295-307页

作者： Bowen Ji fanqi sun Jiecheng Guo Yuhao Zhou Xiaoli You Ye Fan Longchun Wang Mengfei Xu Wen Zeng Jingquan Liu Minghao Wang Huijing Hu Honglong Chang Unmanned System Research Institute Northwestern Polytechnical UniversityXi’an 710072China Ministry of Education Key Laboratory of Micro and Nano Systems for Aerospace School of Mechanical EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Collaborative Innovation Center of Northwestern Polytechnical University Shanghai 201108China Institute of Medical Research Northwestern Polytechnical UniversityXi’an 710072China College of Electronics and Information Hangzhou Dianzi UniversityHangzhou 310018China National Key Laboratory of Science and Technology on Micro/Nano Fabrication Department of Micro/Nano ElectronicsShanghai Jiao Tong UniversityShanghai 200240China

Bacterial cellulose(BC),a natural biomaterial synthesized by bacteria,has a unique structure of a cellulose nanofiberweaved three-dimensional reticulated *** films can be ultrasoft with sufficient mechanical strength,strong water absorption and moisture retention and have been widely used in facial *** films have the potential to be applied to implantable neural interfaces due to their conformality and moisture,which are two critical issues for traditional polymer or silicone *** this work,we propose a micro-electrocorticography(micro-ECoG)electrode named“Brainmask”,which comprises a BC film as the substrate and separated multichannel parylene-C microelectrodes bonded on the top *** can not only guarantee the precise position of microelectrode sites attached to any nonplanar epidural surface but also improve the long-lasting signal quality during acute implantation with an exposed cranial window for at least one hour,as well as the in vivo recording validated for one *** novel ultrasoft and moist device stands as a next-generation neural interface regardless of complex surface or time of duration.

关键词： recording electrode moisture

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

无烟废旧胶粉改性沥青的制备及抑烟机理

引用

建筑材料学报 2023年第10期26卷 1111-1116,1136页

作者：董宴华丛玉凤孙蕊孙凡淇王常春辽宁石油化工大学石油化工学院辽宁抚顺113001

制备了一种无烟废旧胶粉改性沥青,研究了抑烟剂掺量对改性沥青烟气释放量及性能的影响,分析了抑烟剂的作用机理.结果表明:当抑烟剂掺量为1.0%时,改性沥青的烟气释放量由700 mg/kg降到60 mg/kg,针入度、软化点及延度变化较小,老化性能得... 详细信息

制备了一种无烟废旧胶粉改性沥青,研究了抑烟剂掺量对改性沥青烟气释放量及性能的影响,分析了抑烟剂的作用机理.结果表明:当抑烟剂掺量为1.0%时,改性沥青的烟气释放量由700 mg/kg降到60 mg/kg,针入度、软化点及延度变化较小,老化性能得到了改善;抑烟剂抑制了废旧胶粉的降解,使得改性沥青的初始分解温度升高,残余质量增大,热稳定性得到了提升.

关键词：胶粉沥青烟气抑烟剂

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

公共性艺术设计语言在日用陶瓷设计中的案例分析

引用

设计艺术研究 2017年第6期7卷 98-103页

作者：孙凡琦叶双贵武汉理工大学武汉430070

对精英文化符号的借用、建筑语言的借用、非线性思维等设计语言,以相应案例即日用陶瓷经典作品具体进行阐述,重点分析现代主义和后现代主义时期,西方设计师通过这些设计语言来体现公共性观念的创作与实践及其带来的影响。

关键词：设计语言精英符号建筑语言非线性思维

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

公共艺术的公共性观念对产品设计的创新启示

引用

当代美术家 2017年第6期 64-67页

作者：孙凡琦叶双贵不详

本文简要介绍公共艺术的内涵，重点论述公共性观念的大众化特征、日常性特征、互动性特征，并举例说明。最后提出公共性观念对于产品设计的创新启示为：精英符号大众化、标志性建筑生活化、信息符号产品化。

关键词：公共艺术公共性观念产品设计创新启示

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

纳米球型Mo-MOF材料的调控合成及催化硫醚选择性氧化

引用

高等学校化学学报 2023年第12期44卷 84-92页

作者：郭昊天鲁新环孙凡棋陶艺元段金贵张望周丹夏清华湖北大学有机功能分子合成与应用教育部重点实验室武汉430062 南京工业大学材料化学工程国家重点实验室南京211816

金属有机骨架材料是一种由无机金属离子和有机配体配位组成的复合材料,拥有较高的金属分散度和催化活性.本文采用静态混合溶剂热晶化法,以钼酸为钼源、对苯二甲酸为配体合成了有机骨架材料Mo-MOF.通过X射线衍射(XRD)、傅里叶变换红外光... 详细信息

金属有机骨架材料是一种由无机金属离子和有机配体配位组成的复合材料,拥有较高的金属分散度和催化活性.本文采用静态混合溶剂热晶化法,以钼酸为钼源、对苯二甲酸为配体合成了有机骨架材料Mo-MOF.通过X射线衍射(XRD)、傅里叶变换红外光谱(FTIR)、扫描电子显微镜(SEM)和X射线光电子能谱(XPS)等手段表征了催化剂的形貌、结构和组成.采用静态混合溶剂热法(水和乙醇)合成的Mo-MOF催化剂表现出最佳的催化活性,在未加其它助剂的条件下实现二苯基硫醚与氧气的选择性氧化,并可以得到100%的转化率和86.4%的二苯基亚砜的选择性.

关键词：钼金属有机框架硫醚氧气选择性氧化亚砜

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

双功能金属有机骨架材料的制备及催化烯烃环氧化性能

引用

高等学校化学学报 2022年第11期43卷 125-135页

作者：董妍红鲁新环杨璐孙凡棋段金贵郭昊天张钦峻周丹夏清华湖北大学有机功能分子合成与应用教育部重点实验室武汉430062 南京工业大学材料化学工程国家重点实验室南京211816

采用转动水热晶化的合成方式,以ZnO为锌源制备了锌钴金属有机骨架(ZnCo-MOF)双功能催化剂材料;利用X射线衍射(XRD),傅里叶变换红外光谱(FTIR),扫描电子显微镜(SEM)和X射线光电子能谱(XPS)等手段表征了催化剂的形貌、结构和组成.该催化... 详细信息

采用转动水热晶化的合成方式,以ZnO为锌源制备了锌钴金属有机骨架(ZnCo-MOF)双功能催化剂材料;利用X射线衍射(XRD),傅里叶变换红外光谱(FTIR),扫描电子显微镜(SEM)和X射线光电子能谱(XPS)等手段表征了催化剂的形貌、结构和组成.该催化剂材料在微波加热辅助催化α-蒎烯和α-甲基苯乙烯双烯烃的空气环氧化反应中,在不加任何引发剂或共还原剂条件下,能够高转化率、高选择性地得到环氧化物.使用转动水热晶化法(110 r/min转速)合成的ZnCo-MOF催化剂拥有最佳的催化活性,在对α-蒎烯和α-甲基苯乙烯进行催化环氧化反应时分别得到86.3%和99.8%(摩尔分数)的转化率,对应的环氧化物的选择性分别达到93.8%和94.3%.

关键词：纳米氧化锌双功能材料微波烯烃空气环氧化

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Joint Feature Encoding and Task Alignment Mechanism for Emotion-Cause Pair Extraction

引用

Computers, Materials & Continua 2025年第1期82卷 1069-1086页

作者： Shi Li Didi sun College of Computer and Control Engineering Northeast Forestry UniversityHarbin150040China

With the rapid expansion of social media,analyzing emotions and their causes in texts has gained significant ***-cause pair extraction enables the identification of causal relationships between emotions and their triggers within a text,facilitating a deeper understanding of expressed sentiments and their underlying *** comprehension is crucial for making informed strategic decisions in various business and societal ***,recent research approaches employing multi-task learning frameworks for modeling often face challenges such as the inability to simultaneouslymodel extracted features and their interactions,or inconsistencies in label prediction between emotion-cause pair extraction and independent assistant tasks like emotion and cause *** address these issues,this study proposes an emotion-cause pair extraction methodology that incorporates joint feature encoding and task alignment *** model consists of two primary components:First,joint feature encoding simultaneously generates features for emotion-cause pairs and clauses,enhancing feature interactions between emotion clauses,cause clauses,and emotion-cause ***,the task alignment technique is applied to reduce the labeling distance between emotion-cause pair extraction and the two assistant tasks,capturing deep semantic information interactions among *** proposed method is evaluated on a Chinese benchmark corpus using 10-fold cross-validation,assessing key performance metrics such as precision,recall,and F1 *** results demonstrate that the model achieves an F1 score of 76.05%,surpassing the state-of-the-art by 1.03%.The proposed model exhibits significant improvements in emotion-cause pair extraction(ECPE)and cause extraction(CE)compared to existing methods,validating its *** research introduces a novel approach based on joint feature encoding and task alignment mechanisms,contributing to advancements in emotion-c

关键词： Emotion-cause pair extraction interactive information enhancement joint feature encoding label consistency task alignment mechanisms

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

视网膜母细胞瘤动脉内化疗现状

引用

国际眼科纵览 2024年第6期48卷 476-480页

作者：孙凡淇郭小璇顾华丽首都医科大学第四临床医学院北京100730 首都医科大学附属北京同仁医院儿科北京100730

视网膜母细胞瘤(retinoblastoma,RB)是儿童常见的眼部恶性肿瘤,随着医学技术的不断进步和对患者生活质量的重视,其治疗方法也在不断的演进。近年来,动脉内化疗(intra-arterial chemotherapy,IAC)成为治疗RB的重要手段,其通过眼动脉给药... 详细信息

视网膜母细胞瘤(retinoblastoma,RB)是儿童常见的眼部恶性肿瘤,随着医学技术的不断进步和对患者生活质量的重视,其治疗方法也在不断的演进。近年来,动脉内化疗(intra-arterial chemotherapy,IAC)成为治疗RB的重要手段,其通过眼动脉给药实现肿瘤靶向局部化疗,显著提高了治疗效果并降低了全身不良反应。本文对IAC在RB治疗中技术操作、化疗药物(马法兰、卡铂、拓扑替康)、眼局部与全身不良反应、预后和局限性进行综述,以期为临床上IAC的改良和发展提供参考。

关键词：视网膜母细胞瘤介入治疗动脉内化疗

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Microstructure and Wear/corrosion Resistance of Stainless Steel Laser-alloyed with Mn+W_(2)C, Mn+NiWC and Mn+SiC

引用

Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 283-294页

作者： ZHOU Rui DIAO Xiaogang sun Yixin School of Metallurgical Engineering Jiangsu University of Science and TechnologyZhangjiagang 215600China CITIC Heavy Cast Iron Industry Co. Ltd.Luoyang 417039China

In-situ formed high Mn steel coating reinforced by carbides was formed by laser surface alloying(LSA).Laser alloyed layers on 1Cr18Ni9Ti steel with Mn+W_(2)C(specimen A),Mn+NiWC(specimen B)and Mn+SiC(specimen C)powders were fabricated to improve the wear and corrosion behavior of 1Cr18Ni9Ti steel blades in high speed *** evolution,phases,element distribution,microhardness,wear and corrosion behavior of the laser alloyed layers were *** indicated that high Mn steel matrix composites with undissolved W_(2)C,WC and other in-situ formed carbides were formed by LSA with Mn+W_(2)C and Mn+NiWC while SiC totally dissolved into the high Mn matrix when adding Mn+*** as the binding phase in Ni-WC powder decreased the crack sensitivity of the alloyed layer as compared with the addition of W_(2)C *** improvement in average microhardness was achieved in the matrix in specimen A,B and C,with the value of 615,602 and 277 HV_(0.5),while that of the substrate was 212 HV_(0.5).The increase of microhardness,wear and corrosion resistance is highly corelated to microstructure,formed phases,type and content of carbides,micro-hardness and toughness of the alloyed layers.

关键词： laser surface alloying stainless steel carbide type microstructure wear and corrosion resistance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：