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Alcohol Drinking, Dyslipidemia, and Diabetes： A Population-based Prospective Cohort Study among Inner Mongolians in China

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Biomedical and Environmental Sciences 2016年第8期29卷 555-562页

作者： LIANG Zhu QIU Qiao yan WU Jia Hui ZHOU Jing Wen XU Tian ZHANG Ming zhi ZHANG Yong Hong ZHANG Shao yan Department of Epidemiology School of Public Health Medical College of Soochow University Suzhou 215123 Jiangsu China Jiangsu Key Laboratoty of Preventive and Translational Medicine for Geriatric Diseases School of Public Health Soochow University Suzhou 215123 Jiangsu China KunShan Center for Disease Control And Prevention KunShan 215300 Jiangsu China

Objective No previous studies have evaluated the association between dyslipidemia, alcohol drinking, and diabetes in an Inner Mongolian population. We aimed to evaluate the co-effects of drinking and dyslipidemia on diabetes incidence in this population. Methods The present study was based on 1880 participants from a population-based prospective cohort study among Inner Mongolians living in China. Participants were classified into four subgroups according to their drinking status and dyslipidemia. Multivariate logistic regression analysis and receiver operating characteristic （ROC） curves were used to evaluate the association between alcohol drinking, dyslipidemia, and diabetes. Results During the follow-up period, 203 participants were found to have developed diabetes. The multiva riable-adjusted odds ratios （95% confidence interval） for the incidence of non-dyslipidemia/drinkers, dyslipidemia/non-drinkers, and dyslipidemia/drinkers in diabetic patients were 1.40 （0.82-2.37）, 1.73 （1.17-2.55）, and 2.31 （1.38-3.87）, respectively, when compared with non-dyslipidemia/non-drinkers. The area under the ROC curve for a model containing dyslipidemia and drinking status along with conventional factors （AUC=0.746） was significantly （P=O.003） larger than the one containing only conventional factors （AUC=0.711）. Conclusion The present study showed that dyslipidemia was an independent risk factor for diabetes, and that drinkers with dyslipidemia had the highest risk of diabetes in the Mongolian population. These findings suggest that dyslipidemia and drinkin8 status may be valuable in predicting diabetes incidence.

关键词： Diabetes Dyslipidemia, Drinking, Prospective Cohort study

Astrocytes: a double-edged sword in neurodegenerative diseases

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Neural Regeneration Research 2021年第9期16卷 1702-1710页

作者： zhi-Bin Ding Li-Juan Song Qing Wang Gajendra Kumar Yu-Qing yan Cun-Gen Ma The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine Research Center of NeurobiologyShanxi University of Chinese MedicineTaiyuanShanxi ProvinceChina Institute of Brain Science Shanxi Key Laboratory of Inflammatory Neurodegenerative DiseasesMedical School of Shanxi Datong UniversityDatongShanxi ProvinceChina Department of Neurology Affiliated Shanxi Bethune HospitalShanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Neuroscience City University of Hong KongTat Chee AvenueHong Kong Special Administrative RegionChina

Astrocytes play multifaceted and vital roles in maintaining neurophysiological function of the central nervous system by regulating homeostasis, increasing synaptic plasticity, and sustaining neuroprotective effects. Astrocytes become activated as a result of inflammatory responses during the progression of pathological changes associated with neurodegenerative disorders. Reactive astrocytes(neurotoxic A1 and neuroprotective A2) are triggered during disease progression and pathogenesis due to neuroinflammation and ischemia. However, only a limited body of literature describes morphological and functional changes of astrocytes during the progression of neurodegenerative diseases. The present review investigated the detrimental and beneficial roles of astrocytes in neurodegenerative diseases reported in recent studies, as these cells have promising therapeutic potential and offer new approaches for treatment of neurodegenerative diseases.

关键词： A1 A2 astrocytes neurodegenerative diseases neuroinflammation neuron neuroprotection neurotoxicity polarization reactivity

连续性护理干预在冠脉搭桥术后患者康复中的应用效果

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四川解剖学杂志 2024年第2期32卷 184-186页

作者：刘迁迁何姗姗王艳芳新乡医学院第三附属医院重症医学科新乡453000

目的:探讨连续性护理干预在冠脉搭桥术(CABG)后康复患者的应用效果.方法:选取2020年1月至2023年11月于本院进行CABG治疗的107例冠心病患者为研究对象.根据护理模式,将其分为研究组(n=54,给于常规护理联合连续性护理干预)和对照组(n=53,... 详细信息

目的:探讨连续性护理干预在冠脉搭桥术(CABG)后康复患者的应用效果.方法:选取2020年1月至2023年11月于本院进行CABG治疗的107例冠心病患者为研究对象.根据护理模式,将其分为研究组(n=54,给于常规护理联合连续性护理干预)和对照组(n=53,仅给予常规护理干预).采用统计学方法,比较两组患者健康知识知晓率、心功能(采用6min步行试验评估)、日常生活能力[采用日常生活活动能力量表(ADL)评估]、并发症发生率及护理满意度.结果:干预后,研究组患者健康知识知晓率高于对照组,差异有统计学意义(P<0.05);干预后,研究组患者6min步行距离长于对照组,ADL评分高于对照组,差异均有统计学意义(P<0.05);研究组患者术后并发症总发生率低于对照组,护理满意度高于对照组,差异均有统计学意义(P<0.05).结论:实施连续性护理模式,有利于帮助CABG患者掌握疾病相关知识,改善其心功能及日常生活能力,降低术后并发症总发生率.因其具有预后恢复快等优势,而更易被CABG患者所接受.

关键词：手术后医护冠状动脉旁路移植术生活质量连续性护理

Aberrant Global and Regional Topological Organization of the Fractional Anisotropy-weighted Brain Structural Networks in Major Depressive Disorder

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Chinese Medical Journal 2016年第6期129卷 679-689页

作者： Jian-Huai Chen zhi-Jian Yao Jiao-Long Qin Rui yan Ling-Ling Hua Qing Lu Department of Psychiatry Affiliated Nanjing Brain Hospital Nanjing Medical University Nanjing Jiangsu 210029 China Research Center of Learning Science Southeast University Nanjing Jiangsu 210096 China Research Institute of Suzhou Southeast University Suzhou Jiangsu 215123 China

Background： Most previous neuroimaging studies have focused on the structural and functional abnormalities of local brain regions in major depressive disorder （MDD）. Moreover, the exactly topological organization of networks underlying MDD remains unclear. This study examined the aberrant global and regional topological patterns of the brain white matter networks in MDD patients. Methods： The diffusion tensor imaging data were obtained from 27 patients with MDD and 40 healthy controls. The brain fractional anisotropy-weighted structural networks were constructed, and the global network and regional nodal metrics of the networks were explored by the complex network theory. Results： Compared with the healthy controls, the brain structural network of MDD patients showed an intact small-world topology, but significantly abnormal global network topological organization and regional nodal characteristic of the network in MDD were found. Our findings also indicated that the brain structural networks in MDD patients become a less strongly integrated network with a reduced central role of some key brain regions. Conclusions： All these resulted in a less optimal topological organization of networks underlying MDD patients, including an impaired capability of local information processing, reduced centrality of some brain regions and limited capacity to integrate information across different regions. Thus, these global network and regional node-level aberrations might contribute to understanding the pathogenesis of MDD from the view of the brain network.

关键词： Diffusion Tensor Imaging Graph Theory Analysis Major Depressive Disorder Topological Organization

Study on sputtering Zn（O,S）buffer layers for eco-friendly Cu（In,Ga）Se2 solar cells

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Optoelectronics Letters 2019年第6期15卷 435-438页

作者： SHI Si-han FAN Yu HE zhi-chao ZHOU zhi-qiang LIU fang-fang ZHANG Yi TANG An-dong SUN Yun LIU Wei Tianjin Key Laboratory of Thin Film Devices and Technology Institute of Photoelectronic Thin Film Devices and Technology and Nankai UniversityTianjin 300350China Hanergy Heyuan Mobile Energy Intelligence Manufacture Base Beijing 100031China

An eco-friendly Zn(O,S) film with a wider band gap is emerging as one of the promising Cd-free replacement material,which can be deposited by radio frequency *** effect of sputtering pressure on the Zn(O,S) films properties and the devices performance are studied *** high pressure,the ZnS phase is found in the Zn(O,S) films resulting in a higher barrier at Zn(O,S)/CIGS interface which would lead to a low recombination activation energy(Ea).By reducing sputtering pressure,single phase of Zn(O,S) films are conducive to carrier transport as well as promote the films electric properties,ultimately improving the performance of Zn(O,S)/CIGS solar cells.

关键词： films sputtering interface

Weak-fault diagnosis using state-transition-algorithm-based adaptive stochastic-resonance method

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Journal of Central South University 2019年第7期26卷 1910-1920页

作者： YIN Jin-tian XIE Yong-fang CHEN zhi-wen PENG Tao yanG Chun-hua School of Automation Central South University Changsha 410083 China Hunan Provincial Key Laboratory of Grids Operation and Control on Multi-Power Sources Area Shaoyang University Shaoyang 422000 China

In the early fault period of high-speed train systems, the interested characteristic signals are relatively weak and easily submerged in heavy noise. In order to solve this problem, a state-transition-algorithm (STA)-based adaptive stochastic resonance (SR) method is proposed, which provides an alternative solution to the problem that the traditional SR has fixed parameters or optimizes only a single parameter and ignores the interaction between parameters. To be specific, the frequency-shifted and re-scaling are firstly used to pre-process an actual large signal to meet the requirement of the adiabatic approximate small parameter. And then, the signal-to-noise ratio is used as the optimization target, and the STA-based adaptive SR is used to synchronously optimize the system parameters. Finally, the optimal extraction and frequency recovery of a weak characteristic signal from a broken rotor bar fault are realized. The proposed method is compared with the existing methods by the early broken rotor bar experiments of traction motor. Experiment results show that the proposed method is better than the other methods in extracting weak signals, and the validity of this method is verified.

关键词： stochastic resonance (SR) state-transition-algorithm (STA) fault diagnosis broken rotor bar

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用户角色特性导向的微地图逻辑架构设计

测绘科学 2024年第5期49卷 163-175页

作者：方煜敏张立峰闫浩文何毅王小龙王炳瑄陈鹤升刘耀祥兰州交通大学测绘与地理信息学院地理国情监测技术应用国家地方联合工程研究中心甘肃省地理国情监测工程实验室兰州大学资源环境学院西部环境教育部重点实验室

针对微地图在满足用户个性化和顾及用户需求问题移动端设计的困难，提出了一种以用户角色特性为导向的微地图移动端逻辑架构设计。该设计从微地图移动端的多元用户情景出发获取用户需求信息，结合产品定位与用户需求剖析了微地图移动端... 详细信息

针对微地图在满足用户个性化和顾及用户需求问题移动端设计的困难，提出了一种以用户角色特性为导向的微地图移动端逻辑架构设计。该设计从微地图移动端的多元用户情景出发获取用户需求信息，结合产品定位与用户需求剖析了微地图移动端中用户角色，得到了用户角色具备的双向互动性、操作自由性、简易性、无界限性、延展性、灵动性6个特性。融合用户角色特性与用户体验，将其贯穿于逻辑架构整体设计过程，研究设计出了顾及用户角色特性的微地图移动端逻辑架构。通过问卷调查，收集用户对该逻辑架构设计的评价数据并构建评估指标进行分析，结果表明：该逻辑架构设计达到了用户普遍心理预期，能较好地将用户角色特性融合于产品，设计了具有微地图特色的逻辑架构，有助于用户高效使用微地图移动端服务，推进了移动端与用户关联程度。以用户角色特性为导向的微地图移动端逻辑架构设计可为微地图移动端服务用户提供适宜可行的逻辑骨架支撑。

关键词：微地图移动端平台逻辑架构设计用户角色特性

Auxetic two-dimensional transition metal selenides and halides

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npj Computational Materials 2020年第1期6卷 387-392页

作者： Jinbo Pan yan-fang Zhang Jingda Zhang Huta Banjade Jie Yu Liping Yu Shixuan Du Adrienn Ruzsinszky Zhenpeng Hu Qimin yan Department of Physics Temple UniversityPhiladelphiaPA 19122USA Institute of Physics Chinese Academy of SciencesBeijing 100190China School of Physics Nankai UniversityTianjin 300071China Department of Physics and Astronomy University of MaineOronoME 04469USA

Auxetic two-dimensional(2D)materials provide a promising platform for biomedicine,sensors,and many other applications at the *** this work,utilizing a hypothesis-based data-driven approache,we identify multiple materials with remarkable in-plane auxetic behavior in a family of buckled monolayer 2D *** materials are transition metal selenides and transition metal halides with the stoichiometry MX(M=V,Cr,Mn,Fe,Co,Cu,Zn,Ag,and X=Se,Cl,Br,I).First-principles calculations reveal that the desirable auxetic behavior of these 2D compounds originates from the interplay between the buckled 2D structure and the weak metal-metal interaction determined by their electronic *** observe that the Poisson’s ratio is sensitive to magnetic order and the amount of uniaxial stress applied.A transition from positive Poisson’s ratio(PPR)to negative Poisson’s ratio(NPR)for a subgroup of MX compounds under large uniaxial stress is *** work provides a guideline for the future design of 2D auxetic materials at the nanoscale.

关键词： materials transition dimensional

Simultaneous PMD Mitigation for Two Polarization Tributaries of a PDM Signal using only One All-Optical Regenerator

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Chinese Physics Letters 2011年第9期28卷 124-127页

作者： CHEN zhi-Yu yan Lian-Shan YI An-Lin PAN Wei LUO Bin Center for Information Photonics and Communications Southwest Jiaotong UniversityChengduSichuan 610031

A scheme of polarization-mode-dispersion(PMD)mitigation in a polarization-division-multiplexing(PDM)system is proposed and demonstrated with 2×10 Gb/s return−to-zero on-off-keying(RZ-OOK)*** mitigation for two polarization tributaries of the PDM signal is achieved based on the self-phase-modulation(SPM)effect and offset filtering in a polarization nonlinear loop *** improvement of eye-diagram-based signal-to-noise ratio(SNR)is 3.5 dB in the presence of a 7.2-ps differential-group delay(DGD)when the pulsewidth of the PDM signal is∼16.6 ps.

关键词： return offset PDM