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S波段TE_(11)输出相对论磁控管永磁包装仿真设计

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强激光与粒子束 2025年第1期37卷 46-52页

作者：崔越秦奋徐莎雷禄容张勇张玉涵中国工程物理研究院应用电子学研究所先进激光与高功率微波全国重点实验室四川绵阳621990 中国工程物理研究院研究生院四川绵阳621900

对一个S波段TE_(11)输出8腔全腔提取相对论磁控管(R8 ACAE-RM)的永磁包装设计进行了初步探索。采用一种内磁块和外磁块相组合的结构,内磁块置于阳极筒内阳极块两端,外磁块置于阳极筒外,在互作用区产生磁感应强度约为0.34 T,轴向均匀区... 详细信息

对一个S波段TE_(11)输出8腔全腔提取相对论磁控管(R8 ACAE-RM)的永磁包装设计进行了初步探索。采用一种内磁块和外磁块相组合的结构,内磁块置于阳极筒内阳极块两端,外磁块置于阳极筒外,在互作用区产生磁感应强度约为0.34 T,轴向均匀区长度为72 mm的磁场,永磁体重量仅为21 kg。相较于传统外磁体系统,该设计可以使磁体重量降低,互作用区磁场强度更加均匀,系统结构更加紧凑,满足高功率微波源系统的轻量化、小型化需求。相对论磁控管选择π模作为其工作模式,通过全腔提取结构输出4个90°扇形TE_(11)模式,最后通过同轴插板模式转换器进行模式转换输出圆波导TE_(11)模式。利用粒子模拟软件对器件仿真模拟,在二极管电压320 kV,永磁体产生的磁场空间下,R8 ACAE-RM获得了1.06 GW的微波输出功率,微波中心频率为2.44 GHz,转换效率约为47%。

关键词：高功率微波永磁包装 TE_(11)模式相对论磁控管模式转换

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高毒力高耐药空肠弯曲菌ST7268血流感染确诊1例

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中华检验医学杂志 2025年第1期48卷 149-152页

作者：王芳高芬刘玥王亚楠许学斌滕州市中心人民医院检验科山东滕州277500 上海市疾病预防控制中心病原生物检定所上海200336 河南农业大学动物医学院国家动物免疫学国际联合研究中心郑州450046

患者女,51岁,因腹痛、呕吐和发热1 d入院。临床诊断急性盆腔炎、子宫腺肌病;予头孢哌酮/舒巴坦钠经验治疗;6 d后血培养报告空肠弯曲菌,9 d后复查血培养阴性治愈出院。菌株形态学结合质谱鉴定为空肠弯曲菌,全基因组测序预测多位点序列型(... 详细信息

患者女,51岁,因腹痛、呕吐和发热1 d入院。临床诊断急性盆腔炎、子宫腺肌病;予头孢哌酮/舒巴坦钠经验治疗;6 d后血培养报告空肠弯曲菌,9 d后复查血培养阴性治愈出院。菌株形态学结合质谱鉴定为空肠弯曲菌,全基因组测序预测多位点序列型(ST)为ST7268(ST464复合群),其具典型高活力、高毒力和多耐药分子特征,属于食源型空肠弯曲菌的侵袭性克隆。

关键词：空肠弯曲菌侵袭性基因组毒力因子多重耐药

Randomized Algorithms for Orthogonal Nonnegative Matrix Factorization

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Journal of the Operations Research Society of China 2023年第2期11卷 327-345页

作者： yong-yong Chen fang-fang Xu College of Mathematics and Systems Science Shandong University of Science and TechnologyQingdao 266590ShandongChina

Orthogonal nonnegative matrix factorization(ONMF)is widely used in blind image separation problem,document classification,and human face *** model of ONMF can be efficiently solved by the alternating direction method of multipliers and hierarchical alternating least squares *** the given matrix is huge,the cost of computation and communication is too ***,ONMF becomes challenging in the large-scale *** random projection is an efficient method of dimensionality *** this paper,we apply the random projection to ONMF and propose two randomized *** experiments show that our proposed algorithms perform well on both simulated and real data.

关键词： Orthogonal nonnegative matrix factorization Random projection method Dimensionality reduction Augmented lagrangian method Hierarchical alternating least squares algorithm

Cross-species single-cell transcriptomics reveals neuronal similarities and heterogeneity in amniote pallium

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Zoological Research 2025年第01期 193-208页

作者： Fu-Bao-Qian Huang Kuo Liao Yu-Nong Sun Zi-Hao Li Yan-Ru Zhang Ping-fang Liao Si-Yuan Jiang Zhi-yong Zhu Duo-Yuan Chen Ying Lei Shi-Ping Liu You-Ning Lin Zhen-Kun Zhuang School of Biology and Biological Engineering South China University of Technology BGI Research College of Life Sciences University of Chinese Academy of Sciences

The amniote pallium, a vital component of the forebrain,exhibits considerable evolutionary divergence across species and mediates diverse functions, including sensory processing, memory formation, and learning. However, the relationships among pallial subregions in different species remain poorly characterized, particularly regarding the identification of homologous neurons and their transcriptional signatures. In this study, we utilized singlenucleus RNA sequencing to examine over 130?000 nuclei from the macaque（Macaca fascicularis） neocortex,complemented by datasets from humans（Homo sapiens）,mice（Mus musculus）, zebra finches（Taeniopygia guttata）,turtles（Chrysemys picta bellii）, and lizards（Pogona vitticeps）,enablingcomprehensivecross-species comparison. Results revealed transcriptomic conservation and species-specific distinctions within the amniote pallium. Notable similarities were observed among cell subtypes, particularly within PVALB+inhibitory neurons,which exhibited species-preferred subtypes. Furthermore,correlations between pallial subregions and several transcription factor candidates were identified, including RARB, DLX2, STAT6, NR3C1, and THRB, with potential regulatory roles in gene expression in mammalian pallial neurons compared to their avian and reptilian counterparts. These results highlight the conserved nature of inhibitory neurons, remarkable regional divergence of excitatory neurons, and species-specific gene expression and regulation in amniote pallial neurons. Collectively,these findings provide valuable insights into the evolutionary dynamics of the amniote pallium.

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Insertion of O—H Bond of Rh(Ⅱ)-methylene Carbene into Alcohols: A Stepwise Mechanism More Plausible than a Concerted Mechanism

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Chemical Research in Chinese Universities 2007年第2期23卷 221-225页

作者： LIU Zhen-feng WANG yong yue Xian-fang HAN Ke-li State Key Laboratory of Molecular Reaction Dynamics Dalian Institute of Chemical Physics Chinese Academy of Sciences Dcdian 116023 P. R. China

The mechanisms of insertion of O-H bond of Rh（ Ⅱ ）-methylene carbene into methanol and ethanol were studied by using B3LYP functional both in gas phase and in CH2 C12. The formation of free alcoholic oxonium ylides is found to be impossible. Alcoholic oxonium ylide are formed as the intermediates before beth the stepwise and the concerted transition states of insertion of O-H bend of Rh（ Ⅱ ）-methylene carbene into methanol and ethanol. With re- gard to the mechanisms of insertion of O-H of Rh（ Ⅱ ） -methylene carbene into alcohols, analysis of the energy bartiers of the two mechanisms indicate that the stepwise mechanism is more plausible than the concerted mechanism.

关键词： Oxonium ylide 1,2-Hydrogen shift Density functional calculation Dirhodium( Ⅱ ) methylene carbene

Adsorption of Xe in zeolite MCM-22

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Chinese Science Bulletin 2002年第7期47卷 542-547页

作者： Chen fang Deng Feng Cheng Mojie yue yong Ye Chaohui State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Wuhan Institute of Physics and MathematicsChinese Academy of Sciences430071WuhanChina State Key Laboratory of Catalysis Dalian Institute of Chemical PhysicsChinese Academy of Sciences116023DalianChina

Adsorption of xenon in zeolite MCM-22, a zeolite containing two separate pore systems, has been investigated in detail by variable temperature (VT) 129Xe NMR spectroscopy. NMR results suggest that Xe atoms are preferentially adsorbed in the supercages of the zeolite at low Xe pressure (less than a few atmosphere), while Xe atoms can penetrate into the two-dimensional sinusoidal channels at high Xe pressure. Exchange of xenon at the different adsorption sites in the same supercage, i.e. xenon atoms in the two pockets and those in the central part of the supercage, was confirmed at 145 K by two-dimensional (2D) 129Xe NMR exchange spectroscopy. The time scale for the exchange is about several milliseconds.

关键词： MCM-22 zeolite adsorption 129Xe NMR.

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起落架深孔型腔电解加工技术研究

电加工与模具 2025年第1期 45-49页

作者：肖雄亮方月娥蒋葳湖南文理学院芙蓉学院湖南常德415000 湖南长沙水利水电职业技术学院电力工程学院湖南长沙410131 中电科星河北斗技术(西安)有限公司陕西西安710021

针对飞机起落架深孔型腔加工时切削应力大、刀具损耗严重、生产周期长的问题,提出一种深孔型腔电解加工技术。通过制定的深孔型腔电解加工方案设计了加工流道结构,同时利用Comsol软件对深孔型腔电解加工过程中的电场、温度场进行数值模... 详细信息

针对飞机起落架深孔型腔加工时切削应力大、刀具损耗严重、生产周期长的问题,提出一种深孔型腔电解加工技术。通过制定的深孔型腔电解加工方案设计了加工流道结构,同时利用Comsol软件对深孔型腔电解加工过程中的电场、温度场进行数值模拟仿真,得到加工间隙内电场、温度场工艺参数的分布变化规律。最后,通过试验实现了起落架深孔型腔结构的高质量制造,获得制件实测点和理论点的平均误差为0.148 mm,型腔表面粗糙度最大值为Ra1.81μm。

关键词：深孔型腔电解加工模拟仿真工艺试验

聚酰亚胺的结构调控对炭分子筛膜微结构与气体分离性能影响的研究进展

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现代化工 2025年第1期45卷 29-33页

作者：岳鑫朋张新儒王永洪太原理工大学化学工程与技术学院山西太原030024 气体能源高效清洁利用山西省重点实验室山西太原030024

分析了聚酰亚胺近程结构和远程结构对炭分子筛膜结构与性能的影响,提出了理想聚酰亚胺结构应具备的特点,并对未来炭分子筛膜的发展做出展望。

关键词：近程结构远程结构分子结构设计炭分子筛膜气体分离

胰高血糖素样肽-1受体激动剂用于2型糖尿病的临床综合评价

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中国医院药学杂志 2025年第2期45卷 197-202页

作者：朱晓冉蔡玥张玥田冬冬方灵芝董占军河北省人民医院药学部河北省临床药学重点实验室

目的：为医疗机构安全合理使用我国上市的7种胰高血糖素样肽-1受体激动剂(glucagon-like peptide-1 receptor agonist,GLP-1 RA)提供评价与遴选依据。方法：应用《中国医疗机构药品评价与遴选快速指南(第二版)》的评价方法，对7种GLP-1... 详细信息

目的：为医疗机构安全合理使用我国上市的7种胰高血糖素样肽-1受体激动剂(glucagon-like peptide-1 receptor agonist,GLP-1 RA)提供评价与遴选依据。方法：应用《中国医疗机构药品评价与遴选快速指南(第二版)》的评价方法，对7种GLP-1 RA的药学特性、有效性、安全性、经济性以及其他属性(包括医保情况、基本药物情况、贮藏条件、药品有效期、全球使用情况和企业信誉度)5个维度开展数字化综合评价。结果：综合评价结果显示度拉糖肽80分、司美格鲁肽78.7分、利拉鲁肽74分、利司那肽65.6分、艾塞那肽65.1分、洛塞那肽64.2分、贝那鲁肽56.5分。其中，度拉糖肽、司美格鲁肽、利拉鲁肽推荐级别为“强推荐”。利司那肽、艾塞那肽、洛塞那肽根据医疗机构是否有替代药物，建议为“弱推荐”或“不推荐”。贝那鲁肽推荐级别为“不推荐”。结论：具有心血管和肾脏保护作用的长效GLP-1 RA度拉糖肽、司美格鲁肽和利拉鲁肽更具遴选优势。GLP-1 RA的临床综合评价，为医疗机构遴选和患者临床合理使用该类降糖药提供技术支持。

关键词：胰高血糖素样肽-1受体激动剂(GLP-1 RA) 临床综合评价药物选择合理用药