检索结果-南通市图书馆

Salicylate enhances expression and function of NMDA receptors in cochlear spiral ganglion neurons

在线全文

学校读者我要写书评

暂无评论

Journal of Otology 2012年第1期7卷 9-14页

作者： GAO Meng fang xiu-you FENG Shuang WANG Ren-jun DENG Li-li SU Ji-ping Department of Otolaryngology Head and Neck Surgery Guangxi Medical UniversityNanningGuangxi 530021 Department of Otolaryngology Head and Neck Surgery Binzhou People HospitalBinzhouShandong 256600 Department of 4^(th)Surgery Ganyu People HospitalLianyugangJiangsu 222100

Objective To study the effect of salicylate on the expression and function of NMDA receptors in spiral ganglion neurons （SGNs）. Methods The mRNA of NR1 subunit of NMDA receptor in modiolus tissues were detected by Real time fluorescence quantitative PCR （FQ-PCR）. NMDA receptor whole-cell currents were recorded using patch clamp in acute isolated SGNs. Results Compared with the control group, salicylate significantly increased the mRNA level of NR1 subunit in SGNs. NMDA of concentrations ranging from 0.1 mM to 10 mM evoked no current in SGNs. NMDA （0. 1mM and 0.5 mM） applied with salicylate （5 mM）, however, induced inward currents （212.6±15.2pA, n=5; 607.9±44.3pA, n=5） in a dose-dependent manner, which could be inhibited by APV. Salicylate alone did not produce any current in SGNs. Conclusion Salicylate increases the expression of NMDA receptors and facilitates the currents mediated by NMDA receptors in SGNs.

关键词： Salicylate NMDA receptor spiral ganglion neurons NR1 subunit

在线全文

学校读者我要写书评

暂无评论

分离性垂直偏斜临床治疗的回顾性分析

国际眼科杂志 2012年第11期12卷 2220-2221页

作者：游秀芳张立贵游秀霞沪滨眼科医院中国山东省滨州市256600

目的:分析分离性垂直偏斜(dissociated vertical deviation,DVD)不同治疗方法的疗效。方法:回顾性分析我院2002-02/2011-08手术和非手术治疗的54例88眼分离性垂直偏斜的治疗效果。结果:非手术组采用转换注视眼方法治疗后,原注视眼视力... 详细信息

目的:分析分离性垂直偏斜(dissociated vertical deviation,DVD)不同治疗方法的疗效。方法:回顾性分析我院2002-02/2011-08手术和非手术治疗的54例88眼分离性垂直偏斜的治疗效果。结果:非手术组采用转换注视眼方法治疗后,原注视眼视力无明显下降,现注视眼视力不仅提高而且眼位达到外观美容效果,满意率75%;手术组近期治疗满意率为81%。两组统计学处理无差异(P>0.05)。结论:非手术转换注视眼方法可以有效矫正DVD患者的上斜视症状,尤其对于单眼DVD和双眼不对称DVD一侧眼为上斜视、对侧眼为隐性上斜视者效果较好。本方法尤其适用于不愿意接受手术治疗、且合并轻中度弱视和屈光不正的儿童患者。手术要根据患者的视力、斜视度、眼球运动情况及是否合并水平斜视等综合分析考虑,将诸多因素充分考虑于术中,提高一次手术的正位率。

关键词：分离性垂直偏斜手术非手术治疗效果

高压氧联合标准外伤大骨瓣减压手术治疗重型颅脑外伤的预后分析

在线全文

学校读者我要写书评

暂无评论

中外医疗 2017年第19期36卷 76-77,80页

作者：万发波韩涛房秀友江苏省连云港市赣榆区人民医院神经外科江苏连云港222100

目的探究重型颅脑外伤中高压氧联合标准外伤大骨瓣减压手术治疗的预后效果。方法方便选择该院2010年1月—2017年3月收治的60例重型颅脑外伤患者,根据出血情况的不同进行分组,颅内未出血患者为对照组,颅内出血患者标记为观察组,分别采用... 详细信息

目的探究重型颅脑外伤中高压氧联合标准外伤大骨瓣减压手术治疗的预后效果。方法方便选择该院2010年1月—2017年3月收治的60例重型颅脑外伤患者,根据出血情况的不同进行分组,颅内未出血患者为对照组,颅内出血患者标记为观察组,分别采用单纯减压术治疗和高压氧联合减压术治疗,比较两组患者手术治疗效果、并发症及康复情况。结果对照组患者抢救成功率为83.33%,死亡率为16.67%,观察组患者抢救成功率90.00%,死亡率为10.00%,观察组患者手术治疗效果显著优于对照组患者(P<0.05);对照组患者术后昏迷GCS评分(9.17±2.10)分,并发症发生率为26.67%,康复优良率为53.33%;观察组患者GCS评分(12.39±1.84)分,并发症发生率为13.33%,康复优良率为70.00%,观察组患者预后情况显著优于对照组(P<0.05)。结论在重型颅脑外伤患者减压手术抢救治疗中,联合高压氧治疗可有效改善受损脑组织缺氧状态,提高脑组织含氧量促进组织和神经功能修复,提高手术治疗效果,降低术后继发脑损伤,安全性和稳定好,有效改善患者术后预后。

关键词：重型颅内损伤高压氧标准外伤大骨瓣减压术预后

RBF-Type Artificial Neural Network Model Applied in Alloy Design of Steels

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2008年第2期15卷 87-90页

作者： you Wei LIU Ya-xiu BAI Bing-zhe fang Hong-sheng Department of Mechanical and Electrical Engineering North China Institute of Science and Technology Beijing 101601 China Department of Electronics and Information Engineering North China Institute of Science and Technology Beijing 101601 China Department of Materials Science and Engineering Tsinghua University Beijing 100084 China

RBF model,a new type of artificial neural network model was developed to design the content of carbon in low-alloy engineering *** errors of the ANN model are：MSE 0.052 1,MSRE 17.85%,and VOF 1.932 *** results obtaine... 详细信息

关键词： radial-basis-function, artificial neural network, carbon alloy design neurobalance

Phyllosphere microbiota:Community dynamics and its interaction with plant hosts

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2021年第2期63卷 297-304页

作者： Tianyu Gong xiu-fang Xin National Key Laboratory of Plant Molecular Genetics CAS Center for Excellence in Molecular Plant SciencesInstitute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China University of the Chinese Academy of Sciences Beijing 100049China The Chinese Academy of Sciences(CAS)and CAS John Innes Centre of Excellence for Plant and Microbial Sciences Shanghai 200032China

Plants are colonized by various microorganisms in natural *** many studies have demonstrated key roles of the rhizosphere microbiota in regulating biological processes such as nutrient acquisition and resistance against abiotic and biotic challenges,less is known about the role of the phyllosphere microbiota and how it is established and *** review provides an update on current understanding of phyllosphere community assembly and the mechanisms by which plants and microbes establish the phyllosphere microbiota for plant health.

关键词： community assembly dysbiosis phyllosphere microbiota plant immunity plant–microbe interaction

Effect of Chromium on CCT Diagrams of Novel Air-Cooled Bainite Steels Analyzed by Neural Network

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2007年第4期14卷 39-42页

作者： you Wei XU Wei-hong LIU Ya-xiu BAI Bing-zhe fang Hong-sheng Department of Mechanical and Electrical Engineering North China Institute of Science and Technology Beijing 101601 China Department of Electronics and Information Engineering North China Institute of Science and Technology Beijing 101601 China Department of Materials Science and Engineering Tsinghua University Beijing 100084 China

The quantitative effects of chromium content on continuous cooling transformation （CCT） diagrams of novel air-cooled bainite steels were analyzed using artificial neural network models. The results showed that the c... 详细信息

关键词： novel air-cooled bainite steel CCT diagram artificial neural network chromium content quantitative effect

Regulation and integration of plant jasmonate signaling:a comparative view of monocot and dicot

在线全文

学校读者我要写书评

暂无评论

Journal of Genetics and Genomics 2022年第8期49卷 704-714页

作者： Shiwei Wan xiu-fang Xin National Key Laboratory of Plant Molecular Genetics CAS Center for Excellence in Molecular Plant SciencesInstitute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China University of Chinese Academy of Sciences Beijing 100049China CAS-JIC Center of Excellence for Plant and Microbial Sciences(CEPAMS) Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China

The phytohormone jasmonate plays a pivotal role in various aspects of plant life,including developmental programs and defense against pests and pathogens.A large body of knowledge on jasmonate biosynthesis,signal transduction as well as its functions in diverse plant processes has been gained in the past two *** addition,there exists extensive crosstalk between jasmonate pathway and other phytohormone pathways,such as salicylic acid(SA)and gibberellin(GA),in co-regulation of plant immune status,fine-tuning the balance of plant growth and defense,and so on,which were mostly learned from studies in the dicotyledonous model plants Arabidopsis thaliana and tomato but much less in ***,existing evidence suggests both conservation and functional divergence in terms of core components of jasmonate pathway,its biological functions and signal integration with other phytohormones,between monocot and *** this review,we summarize the current understanding on JA signal initiation,perception and regulation,and highlight the distinctive characteristics in different lineages of plants.

关键词： Jasmonate Phytohormone Signaling Crosstalk Plant defense Development Stress response

Effect of quenching condition on micro inhomogeneous structure of Al-Fe-Ce amorphous alloy

在线全文

学校读者我要写书评

暂无评论

中国有色金属学会会刊：英文版 2000年第3期10卷 414-417页

作者： ZHANG Lin(张林) BIAN xiu fang(边秀房) WU you shi(吴佑实) LI Hui(李辉) Shandong Univ Technol Coll Mat Sci & Engn Jinan 250061 Peoples R China

The microstructures of liquid and amorphous Al 90 Fe 5Ce 5 alloys were studied by X ray diffraction (XRD), and the crystalline behavior of the amorphous alloy was also investigated by differential scanning calorimetry (DSC). The distinct pre peaks were found on the structure factors of the liquid and amorphous alloys. The quenching temperature affects the pre peak area, but does not affect its position. The reduction of quenching temperature decreases the crystallization temperature and the activation energy of the Al Fe Ce amorphous alloy. Quenched from 1 050 ℃, a novel structure with a fine dispersion of Al nanophase particles homogeneously distributed in the amorphous matrix was obtained. And the sensitivity of the Al Fe Ce amorphous alloy to the quenching temperature reflects the micro inhomogeneity of the melt.

关键词： Al Fe Ce amorphous alloys micro inhomogeneous structure quenching temperature

Determination of the neutron skin thickness from interaction cross section and charge-changing cross section for B,C,N,O,F isotopes

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2016年第3期27卷 153-158页

作者： xiu-fang Li De-Qing fang Yu-Gang Ma Shanghai Institute of Applied Physics Chinese Academy of Sciences University of Chinese Academy of Sciences

The effective neutron and proton root-meansquare radius of stable and unstable nuclei(^(12-15,17)B,^(12-20)C,^(14-21)N,^(16-24)O and ^(18-21,23-26)F) were deduced from the charge-changing cross section,σ_(cc),and the interaction cross sections,σ_I,by using a statistical abrasion-ablation model *** extracted proton radii are in good agreement with the data from the Atomic Data and Nuclear Data Tables within the ***,we can observe that the neutron skin thickness increases monotonously with the increasing neutron number in these isotopes,which is consistent with the systematical trend of theoretical calculations.

关键词：中子皮厚度作用截面同位素变化截面电荷均方根半径测定不稳定核