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Relationship between Muscle Strength, Muscle Mass and BMD in Postmenopausal Female of Zhuang in Guangxi Province of China

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Journal of Biosciences and Medicines 2022年第2期10卷 87-97页

作者： Peizhao Shi Songyi Mo Jiahui Li Qingxiu Feng Yuanxin Huang Xinling Ma Biao Li Ziyang fang Huiling Liu Guangwu Huang Ling Tang Jinhua Wang xiaoyan fang School of Basic Medical Sciences Youjiang Medical University for Nationalities Baise China Department of Orthopedics Affiliated Hospital of Hebei University of Engineering Handan China Department of Clinical Medicine Medical School of Nanjing University Nanjing China Affiliated Hospital of Youjiang Medical University for Nationalities Baise China School of Nursing Youjiang Medical University for Nationalities Baise China West China School of Basic Medical Sciences & Forensic Medicine Sichuan University Chengdu China

Objective: To explore the correlation between muscle strength, muscle mass and bone mineral density (BMD) in Zhuang female population, body composition analysis and grip strength, and to analyze the possible influencing factors of BMD. Methods: 182 postmenopausal women were selected from Guangxi Province of China. Broadband ultrasound attenuation (BUA) was used to evaluate BMD. Grip dynamometer to assess muscle strength. Height, weight and muscle mass of each part were measured by body composition measuring instrument. Body mass index (BMI), skeletal muscle mass index (SMI) and limb skeletal muscle mass (SM) were calculated according to the measurement results. Results: BUA, grip strength and SMI in postmenopausal women of Zhuang nationality showed a decreasing trend with age (p p p r = 0.305, p Conclusion: With the increase of age, the decline rate of muscle strength of postmenopausal Zhuang women in Guangxi is slower than that of BMD and muscle mass. SM can better reflect the BMD level of the body than SMI, and the LSM is the main influencing factor of BMD.

关键词： Muscle Strength Muscle Mass Musculoskeletal System Bone Mineral Density Postmenopausal Females

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降低全现浇钢筋混凝土楼面质量缺陷试验研究

四川建筑科学研究 2015年第4期41卷 155-158页

作者：方晓燕齐平黄淮学院河南驻马店463000

在建筑市场上,全现浇钢筋混凝土楼面的应用实例呈普遍化趋势,克服现浇楼面混凝土工程质量通病势在必行。实践证明,靠传统工艺很难保证现浇混凝土楼面的工程质量。本文以实例介绍了全现浇混凝土楼面的模板支设工艺和混凝土浇筑工艺的探... 详细信息

在建筑市场上,全现浇钢筋混凝土楼面的应用实例呈普遍化趋势,克服现浇楼面混凝土工程质量通病势在必行。实践证明,靠传统工艺很难保证现浇混凝土楼面的工程质量。本文以实例介绍了全现浇混凝土楼面的模板支设工艺和混凝土浇筑工艺的探索改进,成功解决了现浇混凝土楼面的施工技术难题,该施工工艺为陆续开工的群体工程提供了技术指导,并逐步形成公司级工法。

关键词：楼面混凝土模板质量缺陷试验研究

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胚胎实验室质量控制

中华生殖与避孕杂志 2018年第8期38卷 640-642页

作者：方丛梁晓燕中山大学附属第六医院生殖医学研究中心广州510655

胚胎实验室质量控制是辅助生殖技术中重要的一环。通过质量控制,生殖中心的胚胎实验室培养体系得以保持稳定的状态。这对于维持生殖中心良好的妊娠率具有至关重要的作用。良好的质量控制包括胚胎实验室仪器设备、培养液耗材、人员质控... 详细信息

胚胎实验室质量控制是辅助生殖技术中重要的一环。通过质量控制,生殖中心的胚胎实验室培养体系得以保持稳定的状态。这对于维持生殖中心良好的妊娠率具有至关重要的作用。良好的质量控制包括胚胎实验室仪器设备、培养液耗材、人员质控以及定期质控自查。本文将结合本中心实际情况分别对这四方面进行论述。

关键词：胚胎实验室胚胎培养质量控制

Inhibition of the NLRP3 inflammasome attenuates spiral ganglion neuron degeneration in aminoglycoside-induced hearing loss

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Neural Regeneration Research 2025年第10期20卷 3025-3039页

作者： Jia fang Zhuangzhuang Li Pengjun Wang Xiaoxu Zhang Song Mao Yini Li Dongzhen Yu xiaoyan Li Yazhi Xing Haibo Shi Shankai Yin Department of Otolaryngology Head and Neck Surgery Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineOtolaryngology Institute of Shanghai Jiao Tong UniversityShanghai Key Laboratory of Sleep Disordered BreathingShanghaiChina Department of Otorhinolaryngology-Head and Neck Surgery Shanghai Children’s HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina

Aminoglycosides are a widely used class of antibacterials renowned for their effectiveness and broad antimicrobial ***,their use leads to irreversible hearing damage by causing apoptosis of hair cells as their direct *** addition,the hearing damage caused by aminoglycosides involves damage of spiral ganglion neurons upon *** investigate the mechanisms underlying spiral ganglion neuron degeneration induced by aminoglycosides,we used a C57BL/6J mouse model treated with *** found that the mice exhibited auditory deficits following the acute loss of outer hair *** ganglion neurons displayed hallmarks of pyroptosis and exhibited progressive degeneration over *** profiling of these neurons showed significant upregulation of genes associated with inflammation and immune response,particularly those related to the NLRP3 *** of the canonical pyroptotic pathway in spiral ganglion neurons was observed,accompanied by infiltration of macrophages and the release of proinflammatory *** intervention targeting NLRP3 using Mcc950 and genetic intervention using NLRP3 knockout ameliorated spiral ganglion neuron degeneration in the injury *** findings suggest that NLRP3 inflammasome-mediated pyroptosis plays a role in aminoglycoside-induced spiral ganglion neuron *** of this pathway may offer a potential therapeutic strategy for treating sensorineural hearing loss by reducing spiral ganglion neuron degeneration.

关键词： degeneration hearing loss macrophages Mcc950 neuroinflammation NLRP3 inflammasome ototoxicity pyroptosis sensorineural hearing loss spiral ganglion neuron

基于文献分析中药皂苷类治疗脑缺血再灌注的作用机制

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中国实验方剂学杂志 2023年第5期29卷 194-203页

作者：李紫东方晓艳苗明三河南中医药大学药学院郑州450046

脑缺血再灌注是一种发病率高、死亡率高的严重脑血管疾病。近年来,以溶栓、取栓为基础的再灌注治疗是缺血性脑卒中患者的主要治疗方法。众多研究表明中药皂苷类成分可有效干预脑缺血再灌注,中药皂苷干预脑缺血再灌注具有多靶点、多途径... 详细信息

脑缺血再灌注是一种发病率高、死亡率高的严重脑血管疾病。近年来,以溶栓、取栓为基础的再灌注治疗是缺血性脑卒中患者的主要治疗方法。众多研究表明中药皂苷类成分可有效干预脑缺血再灌注,中药皂苷干预脑缺血再灌注具有多靶点、多途径的特点和显著效果,在治疗与预防脑缺血再灌注上显示巨大的潜力。该文以中国知网文献数据库和万方文献数据库为分析来源,SPSS统计归纳用于治疗脑缺血再灌注的中药皂苷的文献数量、CiteSpace对研究的高频关键词进行聚类分析,阐述用于治疗脑缺血再灌注的中药皂苷的研究热点及研究现状。基于文献分析总结近二十年对中药皂苷治疗脑缺血再灌注的动物实验,中药皂苷通过抗炎作用、抑制氧化应激、免疫调节、保护神经细胞、抑制血栓形成和促进溶栓、保护线粒体、修复血脑屏障等途径治疗脑缺血再灌注,归纳各中药皂苷的具体作用机制、治疗效果和信号通路,为中药皂苷治疗脑缺血再灌注的深入研究、新药研发与临床应用提供理论依据。

关键词：脑缺血再灌注中药皂苷作用机制信号通路

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零售企业数字化转型、动态竞争环境与双元创新的关系

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商业经济研究 2023年第3期 42-46页

作者：方肖燕赵倚林罗伯特戈登大学阿伯丁商学院英国阿伯丁AB107RQ 西安工程大学管理学院陕西西安710048

新零售企业数字化转型深度变革,其双元创新方式有效应对了市场需求与资源受限为特征的动态竞争环境变化。本文选取中国A股452家上市的新零售企业作为研究对象,采用分层回归估计与门槛效应检验等方法,理论探讨并实证分析了数字化转型与... 详细信息

新零售企业数字化转型深度变革,其双元创新方式有效应对了市场需求与资源受限为特征的动态竞争环境变化。本文选取中国A股452家上市的新零售企业作为研究对象,采用分层回归估计与门槛效应检验等方法,理论探讨并实证分析了数字化转型与双元创新的关系,并在其中引入动态竞争环境作为调节变量。得出结论:数字化转型显著促进双元创新,且对渐进式创新的促进效果优于对突破式创新的促进效果;动态竞争环境在数字化转型与双元创新中具有双重门槛效应,即动态竞争环境在数字化转型促进双元创新的过程中呈现出“先增强,后抑制”的倒U型调节关系。

关键词：数字化转型动态竞争环境渐进式创新突破式创新新零售企业

Protein-based functional hydrogel improves cutaneous nerve repair and diabetic wound healing

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Nano Research 2025年第1期18卷 586-596页

作者： Hanzhi Lu Mingrui Cui Yi Wang Xinran Du Xinyi Zhou Yuhan fang xiaoyan Gao Ying Peng Jianyong Zhu Guang Yang Fulun Li Department of Dermatology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine College of Biological Science and Medical EngineeringDonghua UniversityShanghai 201620China Clinical Laboratory Medicine Center Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China

Cutaneous nerve regeneration in diabetic wounds remains a challenge for current clinical ***,a natural protein-based functional hydrogel is developed using keratin as the sole matrix,and protocatechuic aldehyde(PA)and zinc ions as the building blocks through dual-dynamic crosslinking reactions of thiol-aldehyde addition and catecholzinc ions *** unique structural design endows the hydrogel with excellent injectability,skin adhesion,self-healing and antibacterial ability,and *** addition,this hydrogel acts as a drug carrier for the loading and sustained release of phellopterin(PP),a natural compound extracted from traditional Chinese medicine Angelica *** findings demonstrate that the PP-loaded hydrogel promotes cutaneous nerve regeneration,angiogenesis and tissue remodeling in the full-thickness wounds in both db/db and streptozotocin-induced C57BL/6 diabetic mice,notably by the synergistic effect of zinc ions and PP,showing a great potential in diabetic wound therapy.

关键词： functional hydrogel cutaneous nerve regeneration dynamic crosslinking diabetic wounds

基于轮廓误差分离的数控随动曲轴磨床性能分析

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机床与液压 2023年第3期51卷 103-108页

作者：房小艳盛晓伟孙以泽上海机床厂有限公司上海磨床研究所上海200093 东华大学机械工程学院上海201620

为寻找合适的误差分离方法,以数控曲轴随动磨床为性能分析对象,将影响曲轴连杆颈轮廓误差的因素分为随动因素和非随动因素;描述曲轴随动磨削的基本原理以及曲轴连杆颈轮廓生成的精确建模方法;提出将轮廓误差分离为随动误差和非随动误差... 详细信息

为寻找合适的误差分离方法,以数控曲轴随动磨床为性能分析对象,将影响曲轴连杆颈轮廓误差的因素分为随动因素和非随动因素;描述曲轴随动磨削的基本原理以及曲轴连杆颈轮廓生成的精确建模方法;提出将轮廓误差分离为随动误差和非随动误差的方法;通过试验数据分析得出数控随动曲轴磨床的性能评价结论。提出的轮廓误差分离方法,为数控随动磨床的性能评价提供方法指导,为误差源识别提供判断依据。

关键词：轮廓误差分离数控随动曲轴磨床性能分析

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离子凝胶法制备纳米壳聚糖及其表征研究

化工新型材料 2016年第12期44卷 194-196页

作者：李晓燕方健潘春娇北京林业大学材料科学与技术学院北京100083

利用离子凝胶法将低分子量的壳聚糖(CS)制成纳米CS,为探讨影响纳米CS粒径的因素,采用正交试验设计分析CS浓度、CS与三聚磷酸钠(TPP)溶液的体积比、搅拌时间和超声时间对粒径大小的影响,通过直观分析和方差分析优化选择。结果表明:CS与TP... 详细信息

利用离子凝胶法将低分子量的壳聚糖(CS)制成纳米CS,为探讨影响纳米CS粒径的因素,采用正交试验设计分析CS浓度、CS与三聚磷酸钠(TPP)溶液的体积比、搅拌时间和超声时间对粒径大小的影响,通过直观分析和方差分析优化选择。结果表明:CS与TPP溶液的体积比影响最大,其次为CS浓度、超声时间和搅拌时间。最佳工艺条件为CS浓度2.5g/L,CS∶TPP=5∶1,搅拌时间为10min,超声时间为30min。用红外光谱(FT-IR)、X射线衍射(XRD)、热重(TG)、X射线光电子衍射(XPS)对其进行表征,FT-IR和XPS分析表明,纳米CS、低分子量CS与原CS的主要化学成分相同;XRD结果表明,随着分子量和粒径的减小,水溶性增强;TG表明3种CS的热稳定性顺序:CS>纳米CS>低分子量CS。

关键词：纳米壳聚糖离子凝胶法粒径结构表征