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EFFECTIVELY IMMUNE SETS AND HYPERIMMUNE SETS

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Chinese Science Bulletin 1986年第7期31卷 500-页

作者：王洁 department of Computer Science Zhongshan University Guangzhou

Effectively immune sets were introduced in a previous paper (see Chinese Journal of Computers, 4(1982), 273.279). It was proved that if A is effectively immune, then its complement A is not immune, so if A is effectively immune, then is not hyperimmune. That is to say, there is a recursive function which major-izes A. In this letter we give a method of the uniformly effective

关键词： complement letter uniformly recursive otherwise infinite integers write

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西咪替丁胶囊稳定性预测

韶关学院学报 2001年第12期22卷 35-37页

作者：潘育方曾志雄广东药学院物理化学教研室广东广州510224 中山市南朗医院广东中山528454

用经典恒温加速试验法对南朗医院生产的西咪替丁胶囊作加速试验探讨其稳定性 .结果表明 ,西咪替丁胶囊在室温 2 5C时含量下降 10 %所需时间为 3. 3.3. .

关键词：西咪替丁加速试验稳定性胶囊

Assessment of embryotoxicity of compounds in cosmetics by the embryonic stem cell test

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Assessment of embryotoxicity of compounds in cosmetics by th...

Dynamic biomechanical effect of lower body positive pressure treadmill training for hemiplegic gait rehabilitation after stroke: A case report

第九届中国实验动物科学年会（2010新疆）

作者： Rui Chen1,2,Jing Chen1,2,Shujun Cheng3.jie Qinl,2,Weiqiang Lil,2,Lirong Zhang4,Hong Jiao3. Xinbing Yu1,2,Xiuming Zhang1,2,Bruce T.Lahn1,2,and Andy Peng Xiang1,2 1 Center for Stem Cell Biology and Tissue Engineering,Sun Yat-sen university,74# zhongshan Road 2, {3., Guangdong.PR china.510080,2The Key Laboratory for Stem Cells and Tissue Engineering,Ministry of Education, {3. 510080,PR china.3.Food Lab of Guangdong Entry-Exit Inspection and Quarantine Technology Center. {3. 510623.PR china.and 4department of Pathophysiology,Guangdong College of Pharmacy, {3. 510006,PR china

Objective The new EU legislations for cosmetics(Seventh Amendment) have laid down deadlines for the replacement of animal tests in *** policy stimulates the acceptance of in vitro approaches to test embryotoxic potentials of compounds in cosmetics *** embryonic stem cell test(EST) designed by The European Centre for the Validation of Alternative Methods(ECVAM) is currently the most promising in vitro assay to predict the embryotoxic potential of *** this study,six selected compounds(hydroquinone,eugenol,dibutyl phthalate,antimony(Ⅲ) oxide,neodymium(Ⅲ) nitrate hydrate,melamine) formerly involved in cosmetic products were selected to test their embryotoxic potentials by the EST.5-Fluorouracil and penicillin G were separately set as positive and negative *** embryotoxic potential was determined by the prediction model(PM),which was calculated from three endpoints,the IC50 3.3.IC50 ES,and ***,eugenol,and antimony(Ⅲ) oxide indicated with strong embryotoxicity,while dibutyl phthalate,neodymium(Ⅲ) nitrate hydrate,and melamine exhibited a weak *** results may provide a valuable attempt to expand the application of EST to the cosmetics field.

关键词： Cosmetics embryotoxicity embryonic stem cell test

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World Journal of Clinical Cases 2021年第3期9卷 632-638页

作者： Hui-fang Tang Bing Yang Qiang Lin Jun-jie Liang Zhi-Wei Mou department of Rehabilitation Medicine The First Affiliated Hospital of Jinan UniversityGuangzhou 510630Guangdong ProvinceChina department of Neurology The First Affiliated Hospital of Jinan UniversityGuangzhou 510630Guangdong ProvinceChina department of Rehabilitation Medicine The Fifth Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510070Guangdong ProvinceChina

BACKGROUND Lower body positive pressure(LBPP)treadmill has potential applications for improving the gait of patients after stroke,but the related mechanism remains *** SUMMARY A 62-year-old male patient suffered from ischemic stroke with hemiplegic *** was referred to our hospital because of a complaint of left limb weakness for 2 *** LBPP training was performed one session per day and six times per week for 2 *** dynamic plantar pressure analysis was taken every 2 ***,three-digital gait analysis and synchronous electromyography as well as clinical assessments were taken before and after LBPP intervention and at the 4-wk *** LBPP training,our patient not only improved his lower limb muscle strength and walking speed,but more importantly,the symmetry index of various biomechanical indicators ***,the patient’s planter pressure transferring from the heel area to toe area among the LBPP training process and the symmetry of lower body biomechanical parameters *** In this study,we documented a dynamic improvement of gait performance in a stroke patient under LBPP training,which included lower limb muscle strength,walking speed,and symmetry of lower limb *** study provides some crucial clues about the potential dynamic mechanism for LBPP training on gait and balance improvement,which is related to rebuilding foot pressure distribution and remodeling symmetry of biomechanics of the lower limb.

关键词： Lower body positive pressure treadmill Dynamic plantar pressure Stroke Gait analysis Electromyography Case report Rehabilitation

标准化围手术期护理在采用套管支架的尿道成形术患儿中的效果观察

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广州医科大学学报 2024年第2期52卷 65-68页

作者：闫秀兰赵芳段杰蒋怡文易婷婷桂林医学院附属医院小儿外科广西桂林541001

目的:针对采用自制套管支架管治疗的尿道下裂患儿为其制定标准化围手术期护理,探讨与常规围手术期护理对比,分析其优势及可行性。方法:选取2020年7月至2023.6月入住我院小儿外科的164例因诊断尿道下裂需手术治疗的患儿作为研究对象,按... 详细信息

目的:针对采用自制套管支架管治疗的尿道下裂患儿为其制定标准化围手术期护理,探讨与常规围手术期护理对比,分析其优势及可行性。方法:选取2020年7月至2023.6月入住我院小儿外科的164例因诊断尿道下裂需手术治疗的患儿作为研究对象,按单盲试验原则随机分为对照组和试验组。对照组实施常规护理干预,试验组采用标准化围手术期护理。比较两组患儿家属满意度、住院天数、住院费用、尿道感染、尿瘘及出院后随访尿道狭窄、排尿射程情况。结果:试验组患儿住院时间、总费用、术后泌尿系感染、尿道狭窄术后并发症、患儿术后恢复后排尿射程的差异有统计学意义。结论:针对采用自制套管支架管治疗的尿道下裂患儿,为患儿及家属制定标准化的术前至术后整个治疗期间护理措施,可明显减少患儿住院时间,降低治疗总费用,积极促进术后康复进程,也有助于减少尿道下裂手术相关并发症,让患儿取得更好的治疗效果。

关键词：标准化围手术期护理尿道下裂自制套管支架管超前宣教

Server-Aided Multi-Secret Sharing Scheme for Weak Computational Devices

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Computers, Materials & Continua 2018年第9期56卷 401-414页

作者： En Zhang Xintao Duan Siuming Yiu Junbin fang Zoe L.Jiang Tsz HonYuen jie Peng College of Computer and Information Engineering Henan Normal UniversityXinxiang453007China Lab of Intelligence Business&Internet of Things of Henan Province Xinxiang453007China department of Computer Science University of Hong KongHong KongChina department of Optoelectronic Engineering Jinan UniversityGuangzhou510632China School of Computer Science and Technology Harbin nstitute of Technology Shenzhen Graduate SchoolShenzhen518055China Huawei Singapore

In the setting of(t,n)threshold secret sharing,at least t parties can reconstruct the secret,and fewer than t parties learn nothing about the ***,to achieve fairness,the existing secret sharing schemes either assume a trusted party exists or require running multi-round,which is not practical in a real *** addition,the cost of verification grows dramatically with the number of participants and the communication complexity is O(t),if there is not a trusted combiner in the reconstruction *** this work,we propose a fair server-aided multi-secret sharing scheme for weak computational *** malicious behavior of clients or server providers in the scheme can be verified,and the server provider learns nothing about the secret shadows and the *** other secret sharing schemes,our scheme does not require interaction among users and can work in asynchronous mode,which is suitable for mobile networks or cloud computing environments since weak computational mobile devices are not always ***,in the scheme,the secret shadow is reusable,and expensive computation such as reconstruction computation and homomorphic verification computation can be outsourced to the server provider,and the users only require a small amount of computation.

关键词： Secret sharing server-aided non-interactive fairness

ShRNA-mediated gene silencing of β-catenin inhibits growth of human colon cancer cells

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World Journal of Gastroenterology 2007年第48期13卷 6581-6587页

作者： Wen-Sheng Huang Jian-Ping Wang Ting Wang jie-Yu fang Ping Lan Jin-Ping Ma Surgery department The First Affiliated Hospital Sun Yat-sen University Guangzhou 510080 Guangdong Province China

AIM: To observe the gene silencing mediated by the specific shRNA targeted against β-catenin and its effect on cell proliferation and cycle distribution in the human colon cancer cell line Colo205. METHODS: Two shRNA plasmid vectors against β-catenin were constructed and transfected into Colo205 cells with LipofectamineTM2000. The down-regulations of β-catenin, c-myc and cyclinD1 expressions were detected by RT-PCR and western blot analysis. The cell proliferation inhibitions were determined by MTT assay and soft agar colony formation assay. The effect of these two β-catenin shRNAs on cell cycle distribution and apoptosis was examined by flow cytometry. RESULTS: These two shRNA vectors targeted against β-catenin efficiently suppressed the expression of β-catenin and its down stream genes, c-myc and cyclinD1. The expression inhibition rates were around 40%-50% either at the mRNA or at the protein level. The shRNA-mediated gene silencing of β-catenin resulted in significant inhibition of cell growth both on the culture plates and in the soft agar. Moreover, the cancer cells showed significant G0/G1 arrest and increased apoptosis at 72 h post transfection due to gene silencing. CONCLUSION: These specific shRNAs targeted against β-catenin could have a gene silencing effect and block the WNT signaling pathway. They could inhibit cell growth, increase apoptosis, and induce cell cycle arrest in Colo205 cells. ShRNA interference against β-catenin is of potential value in gene therapy of colon cancer.

关键词： β-catenin RNA interference Apoptosis Colon cancer WNT

Trends and sex differences in atrial fibrillation hospitalization and catheter ablation at tertiary hospitals in china.from 2013.to 2016

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Journal of Geriatric Cardiology 2022年第4期19卷 292-300页

作者： Kang LI fang-fang FAN Peng-Fei SUN jie JIANG Jing ZHOU Ying SHI Hai-Bo WANG Jian-Ping LI Yan ZHANG Yong HUO department of Cardiology Peking University First HospitalBeijingChina Scientific Project department China Standard Medical Information Research CentreShenzhenChina Clinical Trial Unit the First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhouChina

BACKGROUND Catheter ablation for atrial fibrillation(AF)is commonly performed ***,the clinical charac-teristics of hospitalized patients with AF and national trends in catheter ablation at tertiary hospitals in china.remain *** This study used the Chinese national database(Hospital Quality Monitoring System)from 2013.to 2016,which is a mandatory database that collects the front page of patients’medical records for hospital accreditation,to describe the clinical cha-racteristics of patients with AF as an overall cohort and as subgroups divided by catheter ablation and *** Of 597,919 AF patients first admitted,57,983.patients underwent catheter ablation[56,3.4 cases(97.2%)of radiofre-quency ablation and 1599 cases(2.8%)of cryoablation]at 746 tertiary *** 10%of patients hospitalized with AF at ter-tiary hospitals in china.underwent catheter ablation,and the percentage of patients undergoing catheter ablation was on the rise bet-ween 2013.and 2016,and the number of cases increased by 2.5 *** with AF patients who did not undergo catheter ablation,those who did were younger,more frequently male,and had fewer baseline *** the overall CHA_(2)DS_(2)-VASc score revealed over half of the patients were high-risk,patients who underwent catheter ablation were mostly low-risk(71.2%of males and 59.1%of females).Considering in-hospital adverse events,the overall pericardial tamponade and all-cause death incidences were 0.2%(0.6%in the ablation group)and 1.2%(0.1%in the ablation group),respectively;both of which were higher in females than *** In this study,AF patients who underwent catheter ablation were relatively young,had a low thrombosis risk,and had few comorbidities and adverse *** were older and experienced more complications than males.

关键词： admitted fibrillation tertiary

蜜炼川贝枇杷膏中橙皮甙含量的固相萃取-高效液相色谱法测定

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分析测试学报 2002年第3期21卷 44-47页

作者：朱炳辉方继辉梁艺英陆惠文陈焕光广东省药品检验所检测中心广东广州510180 中山大学化学系广东广州510275

建立了蜜炼川贝枇杷膏中橙皮甙含量测定方法,样品用流动相溶解定容后 ,注入Sep_PakC18 固相萃取微柱 ,取其达到吸附平衡后的流出液作为反相高效液相色谱法测定用的供试液 ,克服了高糖含量基质条件下液 -液萃取法存在的提取不完全的现象 ... 详细信息

建立了蜜炼川贝枇杷膏中橙皮甙含量测定方法,样品用流动相溶解定容后 ,注入Sep_PakC18 固相萃取微柱 ,取其达到吸附平衡后的流出液作为反相高效液相色谱法测定用的供试液 ,克服了高糖含量基质条件下液 -液萃取法存在的提取不完全的现象 ;在3.265～3..65mg/L范围内 ,橙皮甙进样量与峰面积响应值呈良好的线性关系 ,r=0.9999 ;回收率为98 %～102 % ,RSD为1.6 % (n=5) ;结果表明 ,该法简便快速 ,分析结果准确可靠 ,重复性好。

关键词：测定蜜炼川贝枇杷膏橙皮甙固相萃取高效液相色谱法中药分析