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New endoscopic ultrasound techniques for digestive tract diseases: A comprehensive review

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World Journal of Gastroenterology 2015年第16期21卷 4809-4816页

作者： fan-sheng meng Zhao-Hong Zhang Feng Ji Department of Gastroenterology the First Affiliated HospitalZhejiang University Department of Hematology People’s Hospital of Linyi

Endoscopic ultrasound(EUS) is one of the most important modalities for the diagnosis of digestive tract *** has been evolving ever since it was *** techniques such as elastography and contrast enhancement have emerged, increasing the accuracy, sensitivity and specificity of EUS for the diagnosis of digestive tract diseases including pancreatic masses and ***-elastography evaluates tissue elasticity and therefore, can be used to differentiate various ***-enhanced EUS can distinguish benign from malignant pancreatic lesions and lymphadenopathy using the intravenous injection of contrast *** review discusses the principles and types of these new techniques, as well as their clinical applications and limitations.

关键词： Endoscopic ultrasound Elastography Contrast-enhanced New techniques Digestive tractdiseases

Manipulator-based autonomous inspections at road checkpoints:Application of faster YOLO for detecting large objects

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Defence Technology（防务技术） 2022年第6期18卷 937-951页

作者： Qing-xin Shi Chang-sheng Li Bao-qiao Guo Yong-gui Wang Huan-yu Tian Hao Wen fan-sheng meng Xing-guang Duan School of Mechatronical Engineering Beijing Institute of TechnologyBeijing100081China Beijing Advanced Innovation Center for Intelligent Robots and Systems Beijing Institute of TechnologyBeijing100081China State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing100081China

With the increasing number of vehicles,manual security inspections are becoming more laborious at road *** address it,a specialized Road Checkpoints Robot(RCRo)system is proposed,incorporated with enhanced You Only Look Once(YOLO)and a 6-degree-of-freedom(DOF)manipulator,for autonomous identity verification and vehicle *** modified YOLO is characterized by large objects’sensitivity and faster detection speed,named“LF-YOLO”.The better sensitivity of large objects and the faster detection speed are achieved by means of the Dense module-based backbone network connecting two-scale detecting network,for object detection tasks,along with optimized anchor boxes and improved loss *** the manipulator motion,Octree-aided motion control scheme is adopted for collision-free motion through Robot Operating System(ROS).The proposed LF-YOLO which utilizes continuous optimization strategy and residual technique provides a promising detector design,which has been found to be more effective during actual object detection,in terms of decreased average detection time by 68.25%and 60.60%,and increased average Intersection over Union(Io U)by 20.74%and6.79%compared to YOLOv3 and YOLOv4 through *** comprehensive functional tests of RCRo system demonstrate the feasibility and competency of the multiple unmanned inspections in practice.

关键词： Robot applications Object detection Vehicle inspection Identity verification You only look once(YOLO)

Chiral phosphoramidite ligand-modulated palladium auto-tandem catalysis for asymmetric dehydrogenative dienylation of imines with α-alkenes

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Science China Chemistry 2025年

作者： Zhong-sheng Nong Hao-fan Qian Ying-Chun Chen Pu-sheng Wang Liu-Zhu Gong Hefei National Research Center for Physical Sciences at the Microscale and Department of Chemistry University of Science and Technology of China Key Laboratory of Drug Targeting and Drug Delivery System (Sichuan University) Ministry of Education and Sichuan Research Center for Drug Precision Industrial Technology West China School of Pharmacy Sichuan University School of Materials and Chemistry Southwest University of Science and Technology

The development of efficient processes allowing rapid access to complex chiral molecules from easily available alkenes is a long-term pursuit in the synthetic chemistry community. Transition metal-catalyzed asymmetric functionalization of allylic C–H bond represents a unique alternative toward this goal. However, enantioselective dehydrogenative transformation of olefins to value-added optically enriched molecules remains yet to be discovered. Here, we report a highly enantioselective dehydrogenative dienylation of imines with unactivated α-alkenes driven by the synergistic action of palladium complex and carboxylic acid. Chiral phosphoramidite ligands turned out to be superior in modulating the performance of palladium autotandem catalysis and allowed a broad range of α-alkenes and imines to be transformed into chiral dienylamines. Mechanistic studies suggest that the dienes could be in situ generated from α-alkenes through a palladium(0)-mediated dehydrogenative process in the presence of excess benzoquinone oxidants, and then participated in the Pd-chiral phosphoramidite-catalyzed intermolecular vinylogous-type addition to the imines activated by the carboxylic acid co-catalyst. Notably, the second β-H elimination occurring in the dienylation event might be the turnover-limiting step.

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Recent advances in promising drugs for primary prevention of gastroesophageal variceal bleeding with cirrhotic portal hypertension

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Hepatobiliary & Pancreatic Diseases International 2024年第1期23卷 4-13页

作者： Ji-Yao sheng Zi-fan meng Qiao Li Yong-sheng Yang Department of Hepatobiliary and Pancreatic Surgery the Second Hospital of Jilin UniversityChangchun 130041China Jilin Engineering Laboratory for Translational Medicine of Hepatobiliary and Pancreatic Diseases the Second Hospital of Jilin UniversityChangchun 130041China

Background:Gastroesophageal variceal bleeding is one of the most severe complications of patients with *** primary prevention drugs,including non-selectiveβ-blockers,have effectively reduced the incidence of bleeding,their efficacy is limited due to side effects and related *** recent advances in precision medicine,precise drug treatment provides better treatment *** sources:Literature search was conducted in PubMed,MEDLINE and Web of Science for relevant articles published up to May *** on clinical trials was obtained from https://***/and http://***/.Results:The in-depth understanding of the pathogenesis and advances of portal hypertension has enabled the discovery of multiple molecular targets for promising *** to the site of action,these drugs could be classified into four classes:intrahepatic,extrahepatic,both intrahepatic and extrahepatic targets and *** these classes of drugs offer advantages over traditional treatments in prevention of gastroesophageal variceal bleeding in patients with cirrhotic portal ***:This review classified and summarized the promising drugs,which prevent gastroesophageal variceal bleeding by targeting specific markers of pathogenesis of portal hypertension,demonstrating the significance of using the precision medicine strategy to discover and develop promising drugs for the primary prevention of gastroesophageal variceal bleeding in patients with cirrhotic portal hypertension.

关键词： Cirrhotic portal hypertension Target drug Primary prevention Bleeding

Research on the Magnetic Field of NGC 7793 P13 and Other Confirmed Pulsating Ultraluminous X-Ray Sources

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Research in Astronomy and Astrophysics 2022年第11期22卷 207-213页

作者： fan-Liang meng Yuan-Yue Pan Zhao-sheng Li Key Laboratory of Stars and Interstellar Medium Xiangtan UniversityXiangtan 411105China

A pulsating ultraluminous X-ray source(PULX)is a new kind of pulsar(PSR)whose characteristics are different from all known neutron *** magnetic field of PULX is suspected to be the main reason to support its supper Eddington luminosity of *** 7793 P13,which is the second confirmed PULX,can be easily studied due to its nearby position and isolation from other sources in its host *** this paper,we calculate its magnetic field to be∼1.0×10^(12) G based on the continued observations from 2016 to *** magnetic field evolution of NGC 7793 P13 is analyzed,which shows that the source has spent about 10^(4) yr for the field decaying from the simulated initial strength 4.0×10^(14) G to the present *** case of an assumed constant accretion and the limitation of the companion mass,it will be a recycled PSR whose magnetic field is ∼10^(9) G and spin period is a few hundred *** estimate the field strength of the other confirmed PULXs and find main range is 10^(13)-10^(14) *** positions of the magnetic field and spin period are around or below the *** is because these PULXs are in the binary systems and are with the spin-up rate that are 2-3 orders higher than the normal binary *** suggest that PULXs are the accreting magnetars whose multi-pole strong magnetic field can support the supper Eddington *** would be helpful for studying the evolution of the magnetars,the formation of the binary PSRs above the Eddington spin-up line,and the millisecond PSRs with the magnetic field stronger than ∼10^(9) G.

关键词： stars:neutronll(stars:)pulsars stars:evolution stars:magnetic field accretion accretion disks X-rays:bursts stars:magnetars

Zn-air batteries for electric vehicles

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Tungsten 2024年第1期6卷 164-173页

作者： Nai-Qi meng Yu-Xin fan Jing-sheng Cai State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceFudan UniversityShanghai 200438China College of Energy Soochow Institute for Energy and Materials InnovationS(SIEMIS)Key Laboratory of Advanced Carbon Materials and Wearable Energy Technologies of Jiangsu Province Soochow UniversitySuzhou 215006China Institute of New Energy for Vehicles School of Materials Science and EngineeringTongji UniversityShanghai 201804China

The increasingly serious environmental challenges have gradually aroused people's interest in electric *** the last decade,governments and automakers have collaborated on the manufacturing of electric vehicles with high ***-edge battery technologies are pivotal for the performance of electric ***-air batteries are considered as potential power batteries for electric vehicles due to their high ***-air battery researches can be classified into three categories:primary batteries,mechanically rechargeable batteries,and chemically rechargeable *** majority of current studies aim at developing and improving chemically rechargeable and mechanically rechargeable Zn-air *** have tried to use catalytic materials design and device design for Zn-air batteries to make it possible for their applications in electric *** review will highlight the state-of-the-art in primary batteries,mechanically rechargeable batteries,and chemically rechargeable batteries,revealing the prospects of Zn-air batteries for electric vehicles.

关键词： Energy storage Electric vehicles Bifunctional oxygen catalysts Mechanically rechargeable Zn-air batteries Chemically rechargeable Zn-air batteries

Endogenous Candida albicans endophthalmitis in a patient with chronic renal failure on hemodialysis

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 979-981页

作者： meng-Ya Liu Zhi-fan Chen Hao-sheng Liu Qian-Li meng Department of Ophthalmology Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510080Guangdong ProvinceChina The Fourth Affiliated Hospital of Guangzhou Medical University Guangzhou 511400Guangdong ProvinceChina

Dear Editor,We report a rare case of endogenous endophthalmitis caused by Candida albicans in a patient with chronic renal failure concomitant hemodialysis.A 71-year-old man with a history of hypertension and 2-year chronic renal failure on hemodialysis via a native arteriovenous fistula(AVF)was presented to the local hospital due to fever 3wk *** pathogens were detected through blood culture on admission,and his fever gradually subsided with intravenous ceftriaxone *** a week of fever,he experienced progressive blurred vision in both eyes,accompanied by pain and *** magnetic resonance imaging(MRI)of the brain revealed *** had not undergone any previous eye surgeries or trauma.

关键词： hemodialysis albicans fever

L^(p)Solution of Reflected BSDEs with One Continuous Barrier and Quasi-linear Growth Generators

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Acta Mathematicae Applicatae Sinica 2024年第4期40卷 943-953页

作者： sheng-jun fan School of Mathematics China University of Mining and TechnologyXuzhou 221116China

This paper is devoted to solving a reflected backward stochastic differential equation(BSDE in short)with one continuous barrier and a quasi-linear growth generator g,which has a linear growth in(y,z),except the upper direction in case of y1)solutions for the reflected *** also prove that the minimal Lpsolution can be approximated by a sequence of Lpsolutions of certain reflected BSDEs with Lipschitz generators.

关键词： Reflected BSDEs Quasi-linear growth L^(p)solution Existence Comparison theorem

Characterization and wear behavior of WC-0.8Co coating on cast steel rolls by electro-spark deposition

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International Journal of Minerals,Metallurgy and Materials 2009年第6期16卷 707-713页

作者： Jian-sheng Wang Hui-min meng Hong-ying Yu Zi-shuan fan Dong-bai Sun School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China

To prepare high wear resistance and high hardness coatings, electro-spark deposition was adopted for depositing an electrode of a mixture of 92wt%WC＋8wt%Co on a cast steel roll substrate. The coating was characterized by classical X-ray diffractometer （XRD） and scanning electron microscopy （SEM） with energy dispersive X-ray analysis （EDX）. The results indicate that the coating shows nanosized particulate structure and dendritic structure including columnar structure and equiaxed structure. The primary phases of the coating contain Fe3W3C, Co3W3C, Fe2C and Si2W. The coating has a low friction coefficient of 0.13, its average wear-resistance is 3.3 times that of the cast steel roll substrate and the main mechanism is abrasive wear. The maximum microhardness value of the coating is about 1573.9 Hv0.3. The study reveals that the electro-spark deposition process has the characteristic of better coating quality and the coating has higher wear resistance and hardness.

关键词： electro-spark deposition (ESD) WC-Co coatings microstructure wear resistance