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Recent Progress in the Biological Basis of Remodeling Tissue Regeneration Using Nanofibers:Role of Mesenchymal Stem Cells and Biological Molecules

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Journal of Bionic Engineering 2019年第2期16卷 189-208页

作者： Roqia Ashraf Hasham S.Sofi Hern Kim faheem a.sheikh Department of Nanotechnology University of KashmirHazratbalSrinagar-190006Jammu and KashmirIndia Department of Energy Science and Technology Fusion Smart Living Innovation Technology CenterMyongji UniversityYon ginKyonggi-do 17058Republic of Korea

Opening up new and unlimited avenues in the biomedical field,tissue engineering and regenerative medicine,the electrospinning process is considered as a versatile and the most preferred technique for the fabrication of *** tailor-designed nanofibers provide a desirable and bio-inspired physiological niche to cells for better attachment and subsequent *** this review,an attempt is made to explain the importance of various topological and morphological parameters of nanofibrous scaffolds for efficient *** novel approaches(e.g.,appropriate functionalization and extracellular matrix derived from decellularization)utilized for better mimicking and exponential growth of regenerating tissues are also ***,this review highlights the important parameters necessary for the attachment,proliferation and differentiation of the mesenchymal stem cells for tissue *** importance of growth factors and their role after introducing the electrospinning techniques for efficient delivery and their role in the proliferation of mesenchymal stem cells in the different specific lineage(e.g.,tenogenic,chondrogenic,neurogenic and osteogenic differentiation)are discussed.

关键词： electrospinning nanofibers bio-mimicking stem cells bioactive molecules regenerative medicine

A Simple Method of Electrospun Tungsten Trioxide Nanofibers with Enhanced Visible-Light Photocatalytic Activity

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Nano-Micro Letters 2015年第3期7卷 291-297页

作者： Frank Agyemang Ofori faheem a.sheikh Richard Appiah-Ntiamoah Xinsheng Yang Hern Kim Department of Energy Science and Technology Energy and Environment Fusion Technology Center Myongji University Key Laboratory of Advanced Technology of Materials Superconductor and New Energy R&D Center Southwest Jiaotong University

The present study involves the fabrication of tungsten trioxide(WO3) nanofibers by an electrospinning technique using polyvinyl pyrrolidone(PVP)/citric acid/tungstic acid as precursor solution. It was found that the PVP concentration was one of the most crucial processing parameters determining the final properties of WO3 nanofibers. The optimum concentration of PVP was from 75 to 94 g L-1. The average diameter of the nanofibers increases with increasing the PVP concentration, whereas it is decreased after sintering and orthorhombic structure were formed at 500 °C. The photocatalytic properties of the as-synthesized nanofibers were also investigated by degrading methylene blue and twofold efficiency was obtained compared with that of commercial WO3 microparticles.

关键词： Tungsten trioxide Electrospinning Nanofiber Photocatalysis

硅负载离子液体的合成、表征以及其催化甲酸和三乙基胺作为氢源的环己酮还原胺化反应（英文）

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催化学报 2015年第8期36卷 1365-1371页

作者： Ashif H.Tamboli Avinash A.Chaugule faheem a.sheikh Wook-Jin Chung Hern Kim Department of Energy Science and Technology Energy and Environment Fusion Technology CenterMyongji University

A silica supported ionic liquid was synthesized and characterized by scanning electron microscopy(SEM), Fourier transform infrared spectroscopy, X-ray diffraction, N2 adsorption-desorption, and thermogravimetric analysis. All these techniques, especially SEM results indicated the presence of well-defined spherical particles having diameters larger than the pristine silica particles, confirming the successful immobilization of the ionic liquid. The prepared silica supported ionic liquid was used in the reductive amination of cyclohexanone under different conditions with different azeotropic mixtures of formic acid and triethyl amine as a hydrogen source. The catalyst showed efficient catalytic performance and excellent yields of N-cyclohexyl amine derivatives in the range of 58% to 84% at 30 °C. After completion of the reaction, the catalyst was easily recovered by simple filtration and reused for another five cycles without any significant impact on product yields. The obtained catalytic performance indicates that the present catalyst is green, very active, and reusable for the reductive amination of cyclohexanone.

关键词：离子液体催化剂还原胺化硅胶负载环己酮三乙胺合成氢源甲酸

Recent progress in MXenes incorporated into electrospun nanofibers for biomedical application: Study focusing from 2017 to 2022

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Chinese Chemical Letters 2023年第7期34卷 38-44页

作者： Muheeb Rafiq Sami-ullah Rather Taha Umair Wani Anjum Hamid Rather Rumysa Saleem Khan Anees Ellahi Khan Ibtisam Hamid Haseeb A.Khan Abdullah S.Alhomida faheem a.sheikh Nanostructured and Biomimetic Lab Department of NanotechnologyUniversity of Kashmir Hazratbal.Jammu and KashmirSrinagar 190006India Department of Chemical and Materials Engineering King Abdulaziz University.Jeddah 21589Saudi Arabia Research Chair for Biomedical Applications of Nanomaterials Department of BiochemistryCollege of ScienceKing Saud UniversityRiyadh 11451Saudi Arabia

After discovering a new class of two-dimensional(2D) material, i.e., MXene, a further new scope, came into existence for researchers. Due to their remarkable physical, chemical, and biological properties, MXenes find their role in almost every research discipline. They have been used in biosensors, bioimaging,tissue engineering, drug delivery systems, and other areas. The MXenes can be functionalized with a wide range of atoms/molecules, making them diverse materials. Therefore, the potential of using MXenes in nanofibers can be much more than expected. In this review, we will understand the structure, synthesis,and general properties of MXenes. We will explain using MXenes while encasing them into nanofibers,providing their specific properties. For instance, MXenes-incorporated nanofibers are used in biomedical applications, including soft and hard-tissue engineering and delivery of antimicrobials. Furthermore, MXenes, when incorporated into nanofibers, are used in promoting cellular differentiation, wound healing,and neural tissue restoration, which are briefly discussed in this communication.

关键词： MXenes Nanofibers Tissue engineering Antimicrobial Electrospinning

Methanotrophy-driven accumulation of organic carbon in four paddy soils of Bangladesh

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Pedosphere 2022年第2期32卷 348-358页

作者： Nasrin SULTANA Jun ZHAO Yuanfeng CAI G.K.M.Mustafizur RAHMAN Mohammad Saiful ALAM Mohammad faheem Adrian HO Zhongjun JIA State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of SciencesNanjing 210008China University of Chinese Academy of Sciences Beijing 100049China Department of Agroforestry and Environmental Science Faculty of AgricultureSher-e-Bangla Agricultural University(SAU)Sher-e-Bangla NagarDhaka-1207Bangladesh Department of Soil Science Faculty of AgricultureBangabandhu Sheikh Mujibur Rahman Agricultural University(BSMRAU)Gazipur-1706Bangladesh Institute for Microbiology Leibniz Universität HannoverHerrenhäuser Straße 2Building 4104Hannover D-30419Germany

Biological methane oxidation is a crucial process in the global carbon cycle that reduces methane emissions from paddy fields and natural wetlands into the ***,soil organic carbon accumulation associated with microbial methane oxidation is poorly ***,to investigate methane-derived carbon incorporation into soil organic matter,paddy soils originated from different parent materials(Inceptisol,Entisol,and Alfisol) were collected after rice harvesting from four major rice-producing regions in *** microcosm incubation with 5%(volume/volume)^(13) CH_(4),soil^(13) C-atom abundances significantly increased from background level of 1.08% to 1.88%–2.78%,leading to a net methane-derived accumulation of soil organic carbon ranging from 120 to 307 mg kg^(-1).Approximately 23.6%–60.0% of the methane consumed was converted to soil organic carbon during microbial methane *** phylogeny of^(13) C-labeled pmoA(enconding the alpha subunit of the particulate methane monooxygenase) and 16 S rRNA genes further revealed that canonical α(type II) and γ(type I) Proteobacteria were active methane *** within the Methylobacter-and Methylosarcina-affiliated type Ia lineages dominated active methane-oxidizing communities that were responsible for the majority of methane-derived carbon accumulation in all three paddy soils,while Methylocystis-affiliated type IIa lineage was the key contributor in one paddy soil of Inceptisol *** results suggest that methanotroph-mediated synthesis of biomass plays an important role in soil organic matter *** study thus supports the concept that methanotrophs not only consume the greenhouse gas methane but also serve as a key biotic factor in maintaining soil fertility.

关键词： 16S rRNA gene DNA-based stable-isotope probing(DNA-SIP) methane oxidation methanotroph pmoA rice soil soil organic carbon soil organic matter

A STUDY OF GENOTYPIC FREQUENCY OF VARIOUS BLOOD GROUP ALLELES

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A STUDY OF GENOTYPIC FREQUENCY OF VARIOUS BLOOD GROUP ALLELE...

Treatment of Multiple Sclerosis

The 1st Session of 2004 Workshop of Pakistan Academy of Sciences

作者： Mohammad Shoaib Khan faheem Tahir Mubashir Ahmed sheikh Fazli Subhan Birjees Mazhar Kazi Athar Saeed Dil Fariyal Deepa Sikandar Sultan Irshad Ali Musa Kaleem Baloch Public Health Division National Institute of HealthIslamabadPakistan Department of Clinical Pathology Jinnah Postgraduate Medical CentreKarachiPakistan Department of Chemistry Gomal UniversityD.I. KhanPakistan

A random population sample from urban and rural areas of Bannu region, Northwest Frontier Province（NWFP） of Pakistan was screened for distribution of blood groups. The objective was to identify the genotypic frequency of blood groups in the region, in order to comprehend the allelic diversity. Blood grouping was carried out over a period of 16 months from January 2002 to April 2003, and encompassed 2581 subjects, in which 57.09% were male and 42.9% female. These were categorized according to ABO/Rh system. Allele frequency was computed according to HardyWeinberg law. The distribution of phenotypes in the total sample was 0.3623, 0.3103, 0.2507 and0.0767 for groups B, A, O and AB, respectively, with 0.672 Rh-positive（R） and 0.328 Rh-negative（r）. B group was dominant in both the genders, and AB was rare in both males as well as females. The distribution of the alleles in the total sample was 0.345, 0.378 and 0.277 for I A, I B and i, *** studied population exhibited a predominance of group B, in the order of B＞A＞O＞AB, as well as Rh-positive antigen for both male（90.26%） and female（87.98%） subjects within the population,with Rh-negative men and women being 9.74% and 12.02% respectively.

关键词： Alleles gene frequency blood groups Rh factor transfusion Bannu Pakistan

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Neuroscience & Medicine 2016年第2期7卷 74-82页

作者： M. Nadeem O. Mufti I. Ahsan R. Naheed S. M. faheem Muhammad Nadeem MBBS SUNY Buffalo NY USA Owais Mufti MD SUNY Buffalo NY USA Irfan Ahsan MD Abington Memorial Hospital Abington PA USA Rabia Naheed MBBS Fatima Memorial Hospital Lahore Pakistan sheikh Muhammad faheem MBBS University of IOWA Hospital Iowa City IA USA

Background: A new method of immune-based therapies has been made and applied on multiple sclerosis patients in last decades. Some of these treatments have a high efficacy and reasonable side effects. In slowing disease progression, present treatments have significant limitations, but often associated with significant adverse effects of immunosuppression, with having a bit low capability to counter the disability. Methods: This is a review meta-analysis of treatment of multiple sclerosis. Results: Thus a valuable aim for multiple sclerosis clinical research is to introduce more effective therapies. Conclusion: It is absolutely necessary to increase the individualized therapy planes development in respect to make better planes to disease-modifying treatments.

关键词： Immune Sequestration Multiple Sclerosis Non-Specific Immune Modulation Lymphocyte-Targeted Therapy