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Evaluation of Azadirachta indica cultivated in Egypt against biofilm formation by Pseudomonas aeruginosa: Insights from molecular docking studies targeting LasR

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Infectious Diseases Research 2024年第4期5卷 13-26页

作者： Maram Mohammed Mabrouk Aboulwafa Nada Mohamed Mostafa fadia salah youssef Omayma AbdElkarim Eldahshan Abdel Nasser Badawi Singab Faculty of Pharmacy Department of PharmacognosyAin Shams UniversityCairo 11566Egypt Center of Drug Discovery Research and Development Faculty of PharmacyAin Shams UniversityCairo 11566Egypt.

Background:Azadirachta indica(***),commonly known as neem,is a widely distributed medicinal plant in Asia and Africa and is well known to have a wide spectrum of biological *** is considered a skin food that was traditionally used in different cultures to treat a wide range of skin *** was reported to possess antibacterial activity against Pseudomonas aeruginosa(***)which is considered the most common biofilm model *** study aims to investigate the ability of *** cultivated in Egypt to inhibit/reduce the biofilm formation by ***:The microtiter plate assay was used to evaluate the anti-biofilm activity of neem,cultivated in Egypt,leaves against *** as well as the ability to reduce the activity of *** investigate the phytocompounds responsible for their bioactivity and to explore potential interactions between their bioactive components and one of the quorum-sensing regulatory proteins of *** involved in biofilm formation,liquid chromatography-mass spectrometric and molecular docking studies were ***:Results showed that methanol extract of leaves can reduce the formation of *** biofilm at lower concentrations than those reported in other regions with 1.25 mg/mL as the optimum *** two-way analysis of variance revealed the significance of the extract effect and its concentration on the reduction of biofilm formation(P<0.05).Liquid chromatography-mass spectrometric study revealed the presence of fourteen compounds that belong to limonoids and *** docking analysis against LasR,the quorum-sensing regulatory protein,of *** supported these ***,a limonoid,has achieved the highest Libdock score of ***:It was concluded that ***,cultivated in Egypt,leaves can target LasR as a new mechanism of action for biofilm control by *** and therefore could be a good source of leads for ant

关键词： skin burn biofilm neem Azadirachta indica Pseudomonas aeruginosa nimbolinin

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Preparation and Reactions of 2-Methyl-7-（3-methyl-5-oxo-1- phenyl-2-pyrazolin-4-yl）-5-arylthiazolo[3,2-a]- pyrimido[4,5-d]oxazin-4（5H）-one

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Chinese Journal of Chemistry 2011年第7期29卷 1473-1482页

作者： youssef, Mohamed salah K. Abbady, Mohamed S. Ahmed, Ragaa A. Omar, Ahmed A. Chemistry Department Faculty of Science Assiut University Assiut 71516 Egypt

Ethyl 7-amino-3-（3-methyl-5-oxo- 1-phenyl-2-pyrazolin-4-yl）-5-aryl-5H-thiazolo[3,2-a]pyrimidine-6-carboxy- late was hydrolyzed with an ethanolic sodium hydroxide and the sodium salt thus formed underwent cyclization with acetic anhydride to afford 2-methyl-7-（3-methyl-5-oxo-l-phenyl-2-pyrazolin-4-yl）-5-arylthiazolo[3,2-a]- pyrimido[4,5-d]oxazin-4（SH）-one. This compound was transformed to related heterocyclic systems via its reaction with various reagents. The biological activity of the prepared compounds was tested against Gram positive and Gram negative bacteria as well as yeast-like and filamentous fungi. They revealed in some cases excellent biocidal properties.

关键词： thiazolopyrimidooxazinone thiazolopyrimidopyrimidines antimicrobial activity

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The Spectrum of a Rational Function

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Algebra Colloquium 2020年第3期27卷 477-482页

作者： salah Najib Laboratoire ATRES Faculte Polydisciplinaire de Khouribga Universite Sultan Moulay Slimane BP.145Hay EzzaytouneKhouribgaMorocco

Let k be an infinite field,A be a finite set of k,and Q∈k[x](with x=(x_(1),...,X_(n))and n≥2)be a noncons taut *** main goal of this paper is to construct a polynomial P(x)∈k[x]with suitably large partial degrees i... 详细信息

关键词： irreducible and indecomposable polynomial spectrum of rational function field with product formula Hilbert subset

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On Two Natural Extensions of n-normality

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Acta Mathematica Sinica,English Series 2023年第6期39卷 1147-1152页

作者： salah MECHERI Faculty of Mathematics and informatics Mohamed El Bachir El Ibrahimi UniversityBordj Bou ArreridjAlgeria

A bounded linear operator T on a complex Hilbert space H is called n-normal if T^(*)T^(n)=T^(n)T^(*).By Fuglede’s theorem T is n-normal if and only if T^(n)is *** k,n∈*** a bounded linear operator T is said to be of typeⅠk-quasi-n-normal if T^(*k){T^(*)T^(n)-T^(n)T^(*)}T^(k)=0,and T is said to be of typeⅡk-quasi-n-normal if T^(*k){T^(*n)T^(n)-T^(n)T^(*n)}T^(k)=0.1-quasi-n-normal is called *** shall show that(1)typeⅠquasi-2-normal and typeⅡquasi-2-normal are different classes;(2)the intersection of the class of typeⅠquasi-2-normal and the class of typeⅡquasi-2-normal is equal to the class of *** also give some examples of type I k-quasi-n-normal and typeⅡ*** also show that Weyl’s theorem holds for this class of operators and every k-quasi-n-normal operator has a non trivial invariant subspace.

关键词： Normal operator n-normal operator invariant subspace

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RIESZ IDEMPOTENT AND BROWDER'S THEOREM FOR ABSOLUTE-(p,r)-PARANORMAL OPERATORS

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Acta Mathematica Scientia 2012年第6期32卷 2259-2264页

作者： salah Mecheri Department of Mathematics College of ScienceTaibah UniversityP.O.Box 30002Al Madinah Al MunawarahSaudi Arabia

An operator T is said to be paranormal if ｜｜T^2 x ｜｜〉｜｜Tx｜｜^2 holds for every unit vector x. Several extensions of paranormal operators are considered until now, for example absolute-k-paranormal and p-paranormal introduced in [10], [14], respectively. Yamazaki and Yanagida [38] introduced the class of absolute-（p, r）-paranormal operators as a further generalization of the classes of both absolute-k-paranormal and p-paranormal operators. An operator T ∈ B（H） is called absolute-（p, r）-paranormal operator if ｜｜｜T｜p｜T^＊｜^rx｜｜^r 〉｜｜｜T^＊｜^rx｜｜p＋r for every unit vector x ∈ H and for positive real numbers p 〉 0 and r 〉 0. The famous result of Browder, that self adjoint operators satisfy Browder＇s theorem, is extended to several classes of operators. In this paper we show that for any absolute-（p, r）- paranormal operator T, T satisfies Browder＇s theorem and a-Browder＇s theorem. It is also shown that if E is the Riesz idempotent for a nonzero isolated point μ of the spectrum of a absolute-（p, r）-paranormal operator T, then E is self-adjoint if and only if the null space of T -μ, N（T - μ） N（T^＊ - ^μ）.

关键词： absolute-(p, r)-paranormal operator Browder's theorem Weyl's spectrum

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Optimised CNN Architectures for Handwritten Arabic Character Recognition

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Computers, Materials & Continua 2024年第6期79卷 4905-4924页

作者： salah Alghyaline Department of Computer Science TheWorld Islamic Sciences and Education UniversityAmman1101-11947Jordan

Handwritten character recognition is considered challenging compared with machine-printed characters due to the different human writing *** is morphologically rich,and its characters have a high *** Arabic language includes 28 *** character has up to four shapes according to its location in the word(at the beginning,middle,end,and isolated).This paper proposed 12 CNN architectures for recognizing handwritten Arabic *** proposed architectures were derived from the popular CNN architectures,such as VGG,ResNet,and Inception,to make them applicable to recognizing character-size *** experimental results on three well-known datasets showed that the proposed architectures significantly enhanced the recognition rate compared to the baseline *** experiments showed that data augmentation improved the models’accuracies on all tested *** proposed model outperformed most of the existing *** best achieved results were 93.05%,98.30%,and 96.88%on the HIJJA,AHCD,and AIA9K datasets.

关键词： Optical character recognition(OCR) handwritten arabic characters deep learning

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Arabic Optical Character Recognition:A Review

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Computer Modeling in Engineering & Sciences 2023年第6期135卷 1825-1861页

作者： salah Alghyaline Computer Science Department TheWorld Islamic Sciences and Education UniversityAmman1101-11947Jordan

This study aims to review the latest contributions in Arabic Optical Character Recognition(OCR)during the last decade,which helps interested researchers know the existing techniques and extend or adapt them *** study describes the characteristics of the Arabic language,different types of OCR systems,different stages of the Arabic OCR system,the researcher’s contributions in each step,and the evaluationmetrics for *** study reviews the existing datasets for the Arabic OCR and their ***,this study implemented some preprocessing and segmentation stages of Arabic *** study compares the performance of the existing methods in terms of recognition *** addition to researchers’OCRmethods,commercial and open-source systems are used in the *** Arabic language is morphologically rich and written cursive with dots and diacritics above and under the *** of the existing approaches in the literature were evaluated on isolated characters or isolated words under a controlled environment,and few approaches were tested on pagelevel *** comparative studies show that the accuracy of the existing Arabic OCR commercial systems is low,under 75%for printed text,and further improvement is ***,most of the current approaches are offline OCR systems,and there is no remarkable contribution to online OCR systems.

关键词： Arabic Optical Character Recognition(OCR) Arabic OCR software Arabic OCR datasets Arabic OCR evaluation

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Photogrammetry and deep learning for energy production prediction and building-integrated photovoltaics decarbonization

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Building Simulation 2024年第2期17卷 189-205页

作者： Ilyass Abouelaziz youssef Jouane CESI LINEACT 7 bis Av.Robert Schuman51100ReimsFrance CESI LINEACT Parc Club des Tanneries 2 all Foulons67380StrasbourgFrance

Building-Integrated photovoltaics(BIPV)have emerged as a promising sustainable energy solution,relying on accurate energy production predictions and effective decarbonization strategies for efficient *** paper presents a novel approach that combines photogrammetry and deep learning techniques to address the problem of BIPV *** method is called BIM-AITIZATION referring to the integration of BIM data,AI techniques,and automation *** integrates photogrammetric data into practical BIM *** addition,it enhances the precision and reliability of PV energy prediction by using artificial intelligence *** primary aim of this approach is to offer advanced,data-driven energy forecasts and BIPV decarbonization while fully automating the underlying *** achieve this,the first step is to capture point cloud data of the building through photogrammetric *** data undergoes preprocessing to identify and remove unwanted points,followed by plan segmentation to extract the plan *** that,a meteorological dataset is assembled,incorporating various attributes that influence energy production,including solar irradiance parameters as well as BIM ***,machine and deep learning techniques are used for accurate photovoltaic energy predictions and the automation of the entire *** experiments are conducted,including multiple tests aimed at assessing the performance of diverse machine learning *** objective is to identify the most suitable model for our specific ***,a comparative analysis is undertaken,comparing the performance of the proposed model against that of various established BIPV software *** outcomes reveal that the proposed approach surpasses existing software solutions in both accuracy and *** extend its applicability,the approach is evaluated using a building case study,demonstrating its ability to generalize effectively to new bui

关键词： building-integrated photovoltaic(BIPV) deep learning building information modeling photogrammetric building decarbonization

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A New Multi Chaos-Based Compression Sensing Image Encryption

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Computers, Materials & Continua 2023年第7期76卷 437-453页

作者： fadia Ali Khan Jameel Ahmed Suliman A.Alsuhibany Department of Electrical Engineering Riphah International UniversityIslamabad44000Pakistan Department of Computer Science College of ComputerQassim UniversityBuraydah51452Saudi Arabia

The advancements in technology have substantially grown the size of image *** image encryption algorithms have limited capabilities to deal with the emerging challenges in big data,including compression and noise *** image encryption method that is based on chaotic maps and orthogonal matrix is proposed in this *** proposed scheme is built on the intriguing characteristics of an orthogonal *** Schmidt disperses the values of pixels in a plaintext image by generating a random orthogonal matrix using logistic chaotic *** the diffusion process,a block-wise random permutation of the data is performed using *** proposed scheme provides sufficient security and resilience to JPEG compression and channel noise through a series of experiments and security *** enables Partial Encryption(PE)for faster processing as well as complete encryption for increased *** higher values of the number of pixels change rates and unified average change intensity confirm the security of the encryption *** contrast to other schemes,the proposed approach can perform full and partial encryption depending on security requirements.

关键词： Chaos compression image encryption

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Breeding effects on the genotype×environment interaction for yield of durum wheat grown after the Green Revolution:The case of Spain

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The Crop Journal 2020年第4期8卷 623-634页

作者： fadia Chairi Nieves Aparicio Maria Dolores Serret José Luis Araus Section of Plant Physiology University of BarcelonaBarcelonaSpain AGROTECNIO(Center of Research in Agrotechnology) LleidaSpain Instituto de Tecnología Agraria de Castilla y León(ITACyL) ValladolidSpain

This study evaluates the changes caused by breeding in the genotype by environment(G×E)interaction of the durum wheat varieties most widely cultivated in Spain after the Green Revolution.A set of 12 cultivars was tested in 27 environments,which are understood as the combination of different sites,years,and treatments(water regime and planting dates),representative of the durum wheat growing conditions in Spain with average grain yields(GY)ranging between 2.8 and 9.1 Mg ha^-*** most important environmental factors affecting the G×E interaction for yield were themaximum and the mean temperature during the entire crop *** improvement in genetic yield was observed in warm environments and under optimal water conditions that resemble those where the germplasm originated(essentially as advanced lines)before its release in ***,the adaptation of semi-dwarf durum in Spain has shown a tendency to specific adaptation rather than large-scale *** different patterns of selection have been reported due the G×E interaction and changes in the ranking of genotypes:in the high yielding environments(GY>5 Mg ha^-1),plants favor increased water uptake,with higher levels of transpiration and more open stomata(more negative values of carbon isotope composition,δ^13 C,and higher canopy temperature depression,CTD),whereas,in low yielding environments(GY<5 Mg ha^-1)plants close their stomata and favor greater water use efficiency(less negativeδ^13 C values and lower CTD values).

关键词： breeding cultivar dwarf

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