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Open Journal of Epidemiology 2022年第4期12卷 481-491页

作者： fabien christophe ahoya gounongbé Nadège Agbessi Ibrahim Mama Cissé Antoine Vikkey Hinson Faculty of Medicine University of Parakou Parakou Benin Faculty of Health Sciences of Cotonou University of Abomey Calavi Benin

Background: Occupational dermatoses, also called occupational dermatitis or occupational dermatitis, are very common in the workplace and are still a topical subject. All over the world, especially in developed countries. They handicap the professional activities of the workers. Purpose: To determine the epidemiological profile of dermatosis among automobile repair and maintenance garages in Parakou. Methods: It was a cross-sectional and descriptive study carried out from 20 April to 17 May 2020. The sampling method was non-probabilistic. Data collected from a questionnaire, clinical examination and worksite observation were analyzed with Epi Info 7.***.2.1 software. Results: The participation rate was 98.08%. The sex ratio (male/female) was 178. The mean age of the respondents was 25.80 ± 10.22 years. Respondents with less than 5 years of experience in the field were 61.22%. Mechanics were the most numerous. In the sample, 95.81% had frequent skin contact with fuels, 84.08% had contact with motor oils and 15.92% had contact with dilute battery electrolyte solutions. The frequency of dermatosis was 73.46%. Hands and wrists were the most affected seats (47.35%). Some (33.84%) wore them before the start of the activity in the garage but in 66.22% of them, the dermatosis had occurred because of their arrival in the garage. Among these skin diseases, keratoderma predominated at 80.01%. Conclusion: Dermatosis is very common among garage owners in Parakou.

关键词： Dermatosis Garage Owners Automotives Parakou

Profile of Declared Work Accidents at the Parakou Agency of the National Social Security Fund, 2015-2021, Benin

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Occupational Diseases and Environmental Medicine 2023年第4期11卷 167-174页

作者： fabien christophe ahoya gounongbé Luc Bèhanzin Ibrahim Mama Cissé Colette Sylvie Azandjèmè Sandrine Mathe Lompo Germain Kètèhoundjè Faculty of Medicine University of Parakou Parakou Benin National School for the Training of Senior Technicians in Public Health and Epidemiological Surveillance University of Parakou Parakou Benin Regional Institute of Public Health of Ouidah University of Abomey-Calavi Abomey-Calavi Benin Health Sciences Training and Research Unit Joseph Ki-Zerbo University Ouagadougou Burkina Faso

Introduction: Work accidents (WA) have consequences for both the individual and the company. The objective of this study is to study the profile of work accidents declared to the Parakou agency of the National Social Security Fund (CNSS) from 2015 to 2021. Method: This was a descriptive cross-sectional study with retrospective data collection. It concerned workers affiliated with the CNSS in Parakou, victims of declared WA whose file was available and exploitable. The sampling was exhaustive. Data was collected from registers and worker records. The variables studied were socio-demographic and related to the accident. They were analyzed using R version 4.1 software. Results: The annual incidence rate of WA varied from 5.8% in 2015 to 1.7% in 2021. The victims were 90.6% male. There were more subjects aged 28 to 37 years (37.1%). Workers and laborers were the most concerned. Fractures (22.9%) were the major lesions. At 38.5% they sat in the thoracic limbs and at 22.5% in the pelvic limbs. The majority (63.6%) of these accidents occurred in the workplace. The processing industry sector was mainly (52.1%) the place of accidents. Conclusion: The prevalence of WA declared to the agency of the National Social Security Fund of Parakou from 2015 to 2021 is decreasing. The most affected were young people. It is important to assess their socio-economic impacts.

关键词： Accident at Work Declared Agency CNSS Parakou

Profile of Factors of Arduous Work among Healthcare Professionals in Healthcare Facilities in Northern Benin in 2021

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Occupational Diseases and Environmental Medicine 2024年第1期12卷 41-48页

作者： gounongbé ahoya christophe fabien Mama Cissé Ibrahim Lompo Marthe Sandrine Azandjèmè Colette Bèhanzin Luc Faculty of Medicine University of Parakou Parakou Benin Health Sciences Training and Research Unit Joseph Ki-Zerbo University Ouagadougou Burkina Faso Regional Institute of Public Health of Ouidah University of Abomey-Calavi Abomey-Calavi Benin National Training School for Senior Technicians in Public Health and Epidemiological Surveillance University of Parakou Parakou Benin

Introduction: Work environments create the basis for arduous nursing work. This is what led us to research the factors of arduousness in the exercise of the health profession in North Benin, through this study. Methods: This is a cross-sectional and descriptive study which focused on health professionals in the health zones of Parakou-N’dali and Tchaourou. The sampling was an exhaustive census. All health workers who had given their free and informed consent were included. The data was collected using a questionnaire. The variables studied were the factors of arduous work and socio-professional characteristics. The data collected was processed and analyzed with the Epi info 7.***.0.1 software. Results: A total of 692 were surveyed, the participation rate was 85.11% and the sex ratio (M/F) equal to 0.7. The average age was 38 years old. Nurses made up 32.66% of the sample. They were 86.42% subject to night work and 82.66% to alternating work. Overall, 70.23% worked more than 40 hours per week. Between 78.12% and 96.46% of non-specialist doctors, nurses, midwives and biomedical analysis technicians were required to work night shifts. Nurses, midwives, radiology and laboratory technicians were between 89.53% and 97.35%, organized in alternating work. In the sample, 55.20% complained about the insufficient number of work materials, 26.29% handled harmful chemical substances. Among those surveyed, 58.14% had been attacked. Conclusion: All professional categories of caregivers are subject to arduous work. Measures are needed to reverse the situation.

关键词： Hard Work Professionals Health North-Bénin

Auditory Clinical Profile of Nightclub Employees in the City of Parakou in 2021

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Open Journal of Epidemiology 2023年第2期13卷 144-150页

作者： Ibrahim Mama Cissé ahoya christophe fabien gounongbé Ménonli Adjobimey Carmen Abatti Fatiou Ibouraima Khadidjatou Saké Marius Flatin Department of Occupational Health Research Unit University of Parakou Parakou The Republic of Benin Department of Medicine and Medical Specialties University of Abomey-Calavi Abomey-Calavi The Republic of Benin

Introduction: Hearing impairments are common among nightclub workers. The present work aims to study the hearing clinical profile of these employees in the city of Parakou in 2021. Methods: This was a cross-sectional, descriptive analytical study from March 14 to June 15, 2021. It focused on employees of 13 nightclubs in the city of Parakou. Were included in the study, employees with at least 03 months of practice and aged at least 18 to 50 years at most on the date of the survey and who had given their informed consent to participate in the study. Each employee received a questionnaire, an otoscopy and an acoumetry in tune. Noise pollution was measured at each workstation using a sound level meter. Results: A total of 114 employees were collected. The mean age was 26.38 years ± 4.81 and the sex ratio 0.87. The server position was occupied by 65 employees (57%) followed by managers, 19 or 16.70%- and 17-disc jockeys, 14.90%. Among the employees 31.60% exercised between 03 and 09 months. 76.32% were exposed to noise for more than 8 hours per day and 81.58% were exposed to noise for more than 40 hours per week. The sound level at the workstation was for 59 employees (51.75%) between 90 and 100 dB. Tinnitus was the most expressed complaint, respectively 21 (18.40%) on the right and 22 (19.30%) on the left. Rinne’s test was positive in 85.10% of employees. Weber’s test was indifferent to all frequencies in the majority of respondents. Conclusion: Hearing damage among nightclub employees in the city of Parakou is a reality. It is important to put preventive measures in place.

关键词： Hearing Impairment Noise Nightclubs Parakou Benin 2021

Prevalence and Factors Associated with Vitamin D Deficiency in Patients with COVID-19 in Parakou in 2021

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Open Journal of Epidemiology 2023年第4期13卷 385-400页

作者： Ibrahim Mama Cissé Yawa Yayra Vanesa Léonie Adaba ahoya christophe fabien gounongbé Angel Dodji Dossou Mênonli Adjobimey Rose Mikponhoué Antoine Vikkey Hinson Paul Ayelo Moutawakilou Gomina Department of Medicine and Medical Specialities Faculty of Medicine University of Parakou Parakou Benin UER of Biochemistry Faculty of Medicine University of Parakou Parakou Benin National Directorate of Hospital Medicine Ministry of Health Cotonou Parakou Benin Department of Medicine and Medical Specialities University of Abomey-Calavi Abomey-Calavi Benin

Introduction: Coronavirus 19 disease (COVID-19) often presents several serious complications in patients. 25-hydroxyvitamin D [25(OH)D] deficiency is considered a risk factor for severe forms of the disease. Objective: The objective of this work was to determine the prevalence and factors associated with vitamin D deficiency in patients with COVID-19 in Parakou in 2021. Methods: The method used was a descriptive and analytical cross-sectional study with prospective data collection that covered the period of August 1, 2021, to December 30, 2021. It concerned patients with COVID-19, symptomatic or not, in the commune of Parakou, selected by non-probability sampling. The 25(OH)D assay was performed by an enzyme immunoassay using the heterogeneous phase competition technique. Logistic regression was used to determine the factors associated with 25(OH)D deficiency at the 5% threshold. Results: A total of 197 patients with COVID-19 were included in the study with a mean age of 35.4 ± 15.2 years;with a female predominance (52.3%). The overall prevalence of 25(OH)D deficiency was 31.5% (95% CI [25.1 - 38.5]);it was 32.0% in females and 30.8% in males. 25(OH)D deficiency was more observed in patients ≥ 60 years than in patients < 60 years with no significant difference (p = 0.121), and in females (32.0%) than in males (30.8%) with no significant difference either (p = 0.857). Diabetes (p = 0.036), overweight or obesity (p = 0.032), severe disease forms (p = 0.003) and rhinitis (p = 0.009) were significantly associated with 25(OH)D deficiency. Conclusion: One-third of patients with COVID-19 in Parakou in 2021 were 25(OH)D deficient. 25(OH)D deficiency is associated with the severe form of the disease and with comorbidities justifying supplementation of this vitamin to patients with COVID-19.

关键词： COVID-19 25-OH-Vitamin D Parakou

Psycho-Emotional Aspects and Risk Factors Associated with the Onerous Nature of Retirement Concerning Civil Servants within the Public Administration in Parakou (Benin)

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Open Journal of Psychiatry 2016年第2期6卷 143-150页

作者： Anselme Djidonou Tchégnonsi Francis Tognon ahoya christophe fabien gounongbé Thierry Adoukonou Elie Iréti Nethania Ataïgba Houédénou Brice Thierry Hounlèlou Prosper Gandaho Benjamin Fayomi Simon Ayélèroun Akpona Faculty of Medicine University of Parakou Parakou Benin Faculty of Health Science University of Abomey Calavi Abomey Calavi Benin

Background: In 20% of cases, retirement is experienced as a life event with risk of isolation and loneliness. The objective is to study the psycho-emotional aspects and risk factors associated with civil servants onerous retirement. Methods: It was a descriptive and cross-sectional study which involved 233 pensioners met at the Public Treasury’s Revenue Office in Parakou from June 1 to August 30, 2013. Data were collected through an interview on vulnerability criteria, and Hamilton Depression Rating Scale was used in assessing both anxiety level and depressed mood. Results: Pensioners’ average age was 61.1 ± 6.7 years. Males aged 50 to 60 years represented 47.2%. Following the announcement of retirement, 88.9% had feelings of fear, and 75.8% showed moderate to severe anxiety prevalence of which 88.2% were females and 73.9% males. The distribution according to professional categories was as follow: A (77.3%);B (72.6%);C (69.2%);(85.5%);E (85.7%). Retirement risk factors were: dependants (73.1%), age-related disorders (40.3%), lack of health insurance coverage (24.6%) resulting in a depressed mood (36%) strongly associated with a feeling of family and social abandon (87.8% P = 0.02). Conclusion: Depending on job onerousness in each professional category and associated psycho-social risk factors, it is important to implement an adequate action plan in view of promoting pensioners mental health.

关键词： Retirement Anxiety Onerousness Vulnerability Mental Health

Epidemiological Profile of Stress among Health Professionals in Northern Benin in 2021

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Occupational Diseases and Environmental Medicine 2023年第4期11卷 157-166页

作者： gounongbé A. christophe fabien Mama Cissé Ibrahim Bèhanzin Luc Azandjèmè Colette Sylvie Owona Manga Jules Faculty of Medicine University of Parakou Parakou Benin National School for Training of Senior Technicians in Public Health and Surveillance Epidemiology University of Parakou Parakou Benin Regional Institute of Public Health of Ouidah University of Abomey-Calavi Abomey-Calavi Benin Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon

Objective: To study the epidemiological profile of stress among health professionals in North Benin in 2021. Methods: It was a cross-sectional and descriptive study with health professionals in the Parakou-N’dali and Tchaourou health zones. These two areas have a population of 462,942 inhabitants served by two university hospitals, three area hospitals and 19 health centers. Sampling was exhaustive by free and informed consent. The data was collected through a questionnaire. Studied socio-professional characteristics and stress. The level of stress was assessed using the Karasek questionnaire. Results: Of 813 caregivers approached, 692 were investigated. The participation rate was 85.1%. The average age was 38 years old. Subjects aged 28 - 38 were more numerous, as were those aged between 1 and 10 years. The prevalence of stress was 73.8%. Its level was high at 17.8% and very high at 4.5%. Women were affected (76.6%) than men (70.7%). Within the professional category, midwives were the most affected (82.5%). Respondents from the denominational sector were 90.8% reached. Conclusion: Professional stress is endemic in health facilities in northern Benin, particularly faith-based ones. Action must be taken to reduce it.

关键词： Occupational Stress Health Training Parakou-Ndali Zone Tchaourou Benin

Response of C and N cycles to N fertilization in Sphagnum and Molinia-dominated peat mesocosms

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Journal of Environmental Sciences 2019年第3期31卷 264-272页

作者： fabien Leroy Sébastien Gogo christophe Guimbaud André-Jean Francez Renata Zocatelli Christian Défarge Léonard Bernard-Jannin Zhen Hu Fatima Laggoun-Défarge University of Orleans ISTO CNRS ISTO BRGM ISTO University of Orleans LPC2E CNRS LPC2E UMR CNRS 6553 ECOBIO University of Rennes 1 University of Orleans Cellule R&D CETRAHE School of Environmental Science and Engineering Shandong University

Plant communities play an important role in the C-sink function of peatlands. However,global change and local perturbations are expected to modify peatland plant communities,leading to a shift from Sphagnum mosses to vascular plants. Most studies have focused on the direct effects of modification in plant communities or of global change(such as climate warming, N fertilization) in peatlands without considering interactions between these disturbances that may alter peatlands' C function. We set up a mesocosm experiment to investigate how Greenhouse Gas(CO_2, CH_4, N_2O) fluxes, and dissolved organic carbon(DOC)and total dissolved N(TN) contents are affected by a shift from Sphagnum mosses to Molinia caerulea dominated peatlands combined with N fertilization. Increasing N deposition did not alter the C fluxes(CO_2 exchanges, CH_4 emissions) or DOC content. The lack of N effect on the C cycle seems due to the capacity of Sphagnum to efficiently immobilize N. Nevertheless, N supply increased the N_2O emissions, which were also controlled by the plant communities with the presence of Molinia caerulea reducing N_2O emissions in the Sphagnum mesocosms. Our study highlights the role of the vegetation composition on the C and N fluxes in peatlands and their responses to the N deposition. Future research should now consider the climate change in interaction to plants community modifications due to their controls of peatland sensitivity to environmental conditions.

关键词： CO2 and CH4 N2O Peatland Plant community composition Sphagnum moss Graminoid

The miR166-SIHB15A regulatory module controls ovule development and parthenocarpic fruit set under adverse temperatures in tomato

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Molecular Plant 2021年第7期14卷 1185-1198页

作者： Christian Clepet Ravi Sureshbhai Devani Rachid Boumlik Yanwei Hao Halima Morin fabien Marcel Marion Verdenaud Brahim Mania Gwilherm Brisou Sylvie Citerne Gregory Mouille Jean-christophe Lepeltier Shai Koussevitzky Adnane Boualem Abdelhafid Bendahmane Institute of Plant Sciences Paris-Saclay INRAECNRSUniversite Paris-SaclayOrsay 91405France HM Clause Mas Saint-PierreQuartier La GalineSaint-Remy de Provence 13210France Hazera Seeds Ltd Berurim M.P.Shikmim 7983700Israel lnstitut Jean-Pierre Bourgin INRAEVersaillesFrance Present address:Key Laboratory of Horticultural Crop Biology and Germplasm Innovation in South China College of HorticultureSouth China Agricultural UniversityGuangzhou 510642China

Fruit set is inhibited by adverse temperatures,with consequences on *** isolated a tomato mutant producing fruits under non-permissive hot temperatures and identified the causal gene as SIHB15A,belonging to classⅢhomeodomain leucine-zipper transcription ***15A,loss-of-function mu-tants display aberrant ovule development that mimics transcriptional changes occurring in fertilized ovules and leads to parthenocarpic fruit set under optimal and non-permissive temperatures,in field and greenhouse *** cold growing conditions,SIHB15A is subjected to conditional haploinsufficiency and recessive dosage sensitivity controlled by microRNA 166(miR166).Knockdown of SIHB15A alleles by miR166 leads to a continuum of aberrant ovules correlating with parthenocarpic fruit *** with this,plants harboring an Slhb15a-miRNA166-resisiant allele developed normal ovules and were unable to set parthenocarpic fruit under cold *** affinity purification sequencing and RNA-sequencing analyses revealed that SIHB15A is a bifunctional transcription factor expressed in the ovule ***15A binds to the promoters of auxin-related genes to repress auxin signaling and to the promoters of ethylene-related genes to activate their expression.A survey of tomato genetic biodiversity identified pat and pat-1,two historical parthenocarpic mutants,as alleles of *** together,our findings demonstrate the role of SIHB15A as a sentinel to prevent fruit set in the absence of fertilization and provide a mean to enhance fruiting under extreme temperatures.

关键词： parthenocarpy dosage sensitivity HD-Ziplll miRNA166 heat stress cold stress

Towards the integration of nanoemitters by direct laser writing on optical glass waveguides

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Photonics Research 2020年第9期8卷 1541-1550页

作者： XIAOLUN XU AURÉLIE BROUSSIER TIZIANA RITACCO MACKRINE NAHRA fabien GEOFFRAY ALI ISSA SAFI JRADI RENAUD BACHELOT christophe COUTEAU AND SYLVAIN BLAIZE Light nanomaterialsnanotechnologies(L2n)ERL 7004CNRS.University of Technology of Troyes12 rue Marie Curie10004 Troyes CedexFrance Teem Photonics 61 Chemin du Vieux Chêne38246 MeylanFrance Key Laboratory of Advanced Display and System Application Ministry of EducationSchool of Mechatronic Engineering and AutomationShanghai UniversityShanghai 200072China Sino-European School of Technology Shanghai UniversityShanghai 200044China

A major challenge towards nanophotonics is the integration of nanoemitters on optical *** the optical properties of nanoemitters with the benefits of integration and scalability of integrated optics is still a major issue to *** this work,we demonstrate the integration of nanoemitters positioned in a controlled manner onto a substrate and onto an optical ion-exchanged glass waveguide via direct laser writing based on twophoton *** nanoemitters are colloidal CdSe/ZnS quantum dots(QDs)embedded in polymeric *** varying the laser parameters during the patterning process,we make size-controlled QDpolymer nanostructures that were systematically characterized using optical and structural *** as small as 17 nm in height were *** well-controlled QD-polymer nanostructure systems were then successfully integrated onto a new photonic platform for nanophotonics made of an ion-exchanged *** show that our QDs maintain their light emitting quality after integration as verified by photoluminescence(PL)***,QD emission coupled to our waveguides is detected through a home-built fiber-edge coupling PL measurement *** results show the potential for future integration of nanoemitters onto complex photonic chips.

关键词： emitter optical waveguides