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Efficacy and safety of extracorporeal shock wave therapy combined with sodium hyaluronate in treatment of knee osteoarthritis:a systematic review and Meta-analysis

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Journal of Traditional Chinese Medicine 2024年第2期44卷 243-250页

作者： ZHOU Mingwang DONG Zhuanli WEI Changhao FENG Lufa.g WANG Xiaoping LIU Haiping JI Xing yang Kehu LI Shenghua Department of Orthopaedics Gansu Provincial Hospital of Traditional Chinese MedicineLanzhou 730050China Department of Quality Management Lanzhou Petrochemical General HospitalLanzhou 730050China Department of Orthopaedics Lanzhou Petrochemical General HospitalLanzhou 730050China Evidence-Based Social Science Research Center School of Public HealthLanzhou UniversityLanzhou730000China Evidence-Based Medicine Center School of Basic Medical SciencesLanzhou UniversityLanzhou 730000China Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province Lanzhou 730000China Center for Translational Medicine Gansu Provincial Hospital of Traditional Chinese MedicineLanzhou 730050China Department of Orthopaedics Gansu Provincial Hospital of Traditional Chinese MedicineLanzhou 730000China

OBJECTIVE:To assess the efficacy and safety of extracorporeal shockwave therapy(ESWT)combined with sodium hyaluronate(HA)for the treatment of knee osteoarthritis(KOA).METHODS:PubM ed,Embase,the Cochrane Library,Web of Science,China National Knowledge Infrastructure,Wanfa.g database,China Science and Technology Journal Database,and SinoMed were searched from inception to July *** quality of the randomized controlled trials was evaluated independently by two reviewers according to the criteria in the Cochrane Collaboration for Systematic *** identified articles were then screened individually using EndnoteX9 for eligibility in this *** heterogeneity among the articles was evaluated using ***:A total of 17 studies,comprising 2000 individuals,were included in this *** results showed that a significant improvement was observed in knee pain and function based on the clinical efficacy of ESWT combined with *** analysis of clinical efficacy showed that[relative risk(RR)=1.21,95%confidence interval(CI)(1.12,1.30),P<0.01].Statistical analysis of visual analog scale showed that[standardized mean difference(SMD)=-2.84,95%CI(-4.01,-1.66),P<0.01].Western Ontario and McMaster University osteoarthritis index statistical analysis showed that[SMD=-1.57,95%CI(-2.52,-0.61),P<0.01].Lysholm score statistical analysis showed that[SMD=1.71,95%CI(0.98,2.44),P<0.01].In addition,only minor side effects,such as redness and swelling of the skin,were ***:Medium to low quality evidence showed that ESWT combined with HA offers an inexpensive,welltolerated,safe,and effective method to improve pain and functionality in patients with ***,tightly controlled,randomized,large multicenter trials are warranted to validate the current findings.

关键词： osteoarthritis knee randomized controlled trial extracorporeal shockwave therapy hyaluronic acid Meta-analysis

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了忽焉——题曹操宗族墓的八块砖

十月 2024年第1期 220-224页

作者：陈先发不详

Identification of a microRNA switch in spinal commissural axon guidance

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Neural Regeneration Research 2019年第7期14卷 1208-1209页

作者： Guo-fa.Liu Tao yang Department of Biological Sciences University of Toledo

The formation of neural circuits is governed by multiple classes of highly conserved extracellular guidance signals such as guidance cues,growth fa.tors,and cell adhesion molecules(Kolodkin and Tessier-Lavigne,2011;Stoeckli et al.,2018).During embryonic development,vertebrate commissural neurons project axons toward the floor plate and cross the midline of the spinal cord,a process relying upon the coordination of attractive and repulsive guidance cues(Kolodkin and Tessier-Lavigne,2011;Stoeckli et al.,2018).

关键词： formation Identification commissural axon guidance

Internal shrinkage crack in a 10 t water-cooled steel ingot with a large height-to-diameter ratio

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China Foundry 2021年第2期18卷 110-117页

作者： Jing-an yang Hou-fa.Shen School of Transportation Science and Engineering Beihang UniversityBeijing 100191China School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China

Steel ingot with a large height-to-diameter ratio is utilized to produce multiple products by one stock in *** cooling is a usual way to enhance production ***,the combination of the two fa.tors will generate internal defects,such as shrinkage porosity and hot *** characteristic of internal shrinkage crack in a 10 t water-cooled steel ingot with a large height-to-diameter ratio was examined by an ultrasonic test.A slice was sectioned from the ingot middle part where billets containing star-like crack were further *** billets were examined by X-ray high energy industrial CT,and the compactness was reconstructed in three *** near the crack was observed using scanning electron microscopy,and the solidification process and grain size were studied by high temperature confocal ***,thermo-mechanical simulation and post-processing were carried out to analyze the formation of shrinkage porosity and hot crack.A new criterion considering mushy zone mechanical behavior in brittle temperature as well as grain size distribution was proposed to evaluate hot cracking potential in the *** results show that a deep shrinkage porosity band easily forms in the center line of such an ingot with a large height-to-diameter ratio,and water-cooling further generates excessive tensile stress tearing the liquid films around the ***,hot cracks begin to propagate along grain *** grain size in the upper and center of the ingot is large,which leads to an inverted cone shape defects zone in the ingot center.

关键词： steel ingot porosity hot crack industrial CT thermo-mechanical simulation

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江西省主要大学学科结构测度与优化研究

图书馆研究 2024年第3期54卷 120-128页

作者：张发亮周亚阳南昌大学公共政策与管理学院江西南昌330031

大学是由若干不同规模、不同水平的学科构成,其内部学科结构的合理与否对大学未来发展至关重要。为准确评估江西省主要大学的学科发展与结构分布状况,为学科结构优化和大学整体发展提供依据,尝试利用科学计量等方法,定量测度大学内部学... 详细信息

大学是由若干不同规模、不同水平的学科构成,其内部学科结构的合理与否对大学未来发展至关重要。为准确评估江西省主要大学的学科发展与结构分布状况,为学科结构优化和大学整体发展提供依据,尝试利用科学计量等方法,定量测度大学内部学科结构。首先,以江西省具有独立博士点授予权的9所大学为例,基于中外文核心期刊数据,从学科规模、影响力和成长性等维度对内部各学科的发展状况进行测度。其次,基于学科发展等级、学科属性战略坐标等分布情况对大学的学科结构进行评估。最后,总结江西省主要大学的学科结构现状与特点,提出相关优化思路和建议,以推动江西省高等教育与“双一流”工作发展。

关键词：江西省大学学科评价学科结构

维普期刊数据库博看期刊

Influence of confined water on the limit support pressure of tunnel fa.e in weakly water-rich strata

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Journal of Central South University 2024年第8期31卷 2844-2859页

作者： LI Yun-fa.WU Guo-jun CHEN Wei-zhong YUAN Jing-qiang HUO Meng-zhe State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan 430071China University of Chinese Academy of Sciences Beijing 100049China

In the process of shield tunneling through soft soil layers,the presence of confined water ahead poses a significant threat to the stability of the tunnel ***,it is crucial to consider the impact of confined water on the limit support pressure of the tunnel *** study employed the finite element method(FEM)to analyze the limit support pressure of shield tunnel fa.e instability within a pressurized water-containing ***,a multiple linear regression approach was applied to derive a concise solution formula for the limit support pressure,incorporating various influencing *** analysis yields the following conclusions:1)The influence of confined water on the instability mode of the tunnel fa.e in soft soil layers makes the displacement response of the strata not significant when the fa.e is unstable;2)The limit support pressure increases approximately linearly with the pressure head,shield tunnel diameter,and tunnel burial *** inversely proportional to the thickness of the impermeable layer,soil cohesion and internal friction angle;3)Through an engineering case study analysis,the results align well with those obtained from traditional theoretical methods,thereby validating the rationality of the equations proposed in this ***,the proposed equations overcome the limitation of traditional theoretical approaches considering the influence of changes in impermeable layer *** can accurately depict the dynamic variation in the required limit support pressure to maintain the stability of the tunnel fa.e during shield tunneling,thus better reflecting engineering reality.

关键词： weakly water-rich strata confined aquifer limit support pressure finite element method multiple linear regression

科技自立自强的历史逻辑、理论内涵与实现路径

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科学管理研究 2024年第1期42卷 2-10页

作者：宋河发刘安琪中国科学院科技战略咨询研究院北京100190 中国科学院大学公共政策与管理学院(知识产权学院) 北京100149

科技自立自强是我国科技事业进入新发展阶段的新目标。纵观我国科技发展史,党的全面领导是实现科技自立自强的根本保证,独立自主和对外开放相统一是基本原则,提升自主创新能力是制度主线,强化国家战略科技力量是客观要求。科技自立自强... 详细信息

科技自立自强是我国科技事业进入新发展阶段的新目标。纵观我国科技发展史,党的全面领导是实现科技自立自强的根本保证,独立自主和对外开放相统一是基本原则,提升自主创新能力是制度主线,强化国家战略科技力量是客观要求。科技自立自强与自力更生和自主创新一脉相承,科技自立自强是指我国能够依靠自身力量创造出适合发展需要的足够数量的高水平科技成果和知识产权,这些科技成果和知识产权能够有效支撑我国产业创新和经济社会发展,强调通过自主研发、自主生产和自主应用来减少对外部科技资源的依赖,从根本上提高自主创新能力和综合国力。为实现科技自立自强,必须坚持党的全面领导,持续深化科技体制改革,进一步完善科技创新政策体系、知识产权严格保护制度、科技创新生态体系和科技评价考核制度,建设科研兴趣导向的高水平科技人才队伍。

关键词：科技自立自强历史逻辑理论内涵实现路径

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管桁架焊缝质检机器人夹紧机构轻量化设计

机械设计与制造 2024年第3期 326-329,334页

作者：陈玉发靳壮壮曹阳魏晓雍中铁五局集团建筑工程责任有限公司贵州贵阳550002 贵州大学机械工程学院贵州贵阳550025

为减轻管桁架焊缝质量检测机器人结构重量,文章在分析夹紧机构运动约束及其关键零部件强度约束的基础上,建立夹紧机构各主要零部件力学和运动学模型,运用惩罚函数法对夹紧机构尺寸进行优化。支腿在夹紧机构的零部件中质量较大,经静力学... 详细信息

为减轻管桁架焊缝质量检测机器人结构重量,文章在分析夹紧机构运动约束及其关键零部件强度约束的基础上,建立夹紧机构各主要零部件力学和运动学模型,运用惩罚函数法对夹紧机构尺寸进行优化。支腿在夹紧机构的零部件中质量较大,经静力学分析发现支腿材料冗余较大,采用拓扑优化进一步减轻支腿重量。结果表明:夹紧架、支腿和底板尺寸分别为60mm、88mm、111mm时,结构最为紧凑;拓扑优化重构后,支腿的质量减轻了121.2g,总质量减少了16.16%。

关键词：夹紧机构轻量化尺寸优化支腿拓扑优化

Rotor broken bar fa.lt diagnosis for induction motors based on double PQ transformation

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第8期8卷 1320-1329页

作者： HUANG Jin yang Jia-qiang NIU fa.liang School of Electrical Engineering Zhejiang University Hangzhou 310027 China

A new rotor broken bar fa.lt diagnosis method for induction motors based on the double PQ transformation is pre-sented. By distinguishing the different patterns of the PQ components in the PQ plane,the rotor broken bar fa.lt can be detected. The magnitude of power component directly resulted from rotor fa.lt is used as the fa.lt indicator and the distance between the point of no-load condition and the center of the ellipse as its normalization value. Based on these,the fa.lt severity fa.tor which is completely independent of the inertia and load level is defined. Moreover,a method to reliably discriminate between rotor fa.lts and periodic load fluctuation is presented. Experimental results from a 4 kW induction motor demonstrated the validity of the proposed method.

关键词： PQ transformation fa.lt diagnosis Load fluctuation fa.lt severity fa.tor Induction motors