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Design and Verification of Parallel hip Exoskeleton Considering Output Torque Anisotropy

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Journal of bionic Engineering 2024年第3期21卷 1305-1320页

作者： Jilong xu Yunzhan Niu fucai liu Engineering Research Center of the Ministry of Education for Intelligent Control system and Intelligent Equipment Yanshan UniversityQinhuangdao066004China Key Laboratory of Industrial Computer Control Engineering of heibei Province Yanshan UniversityQinhuangdao066004China College of Mechanical Engineering Yanshan UniversityQinhuangdao066004China

In rehabilitation training,it is crucial to consider the compatibility between exoskeletons and human legs in ***,most exoskeletons today adopt an anthropomorphic serial structure,which results in rotational centers that are not precisely aligned with the center of the hip *** address this issue,we introduce a novel exoskeleton called the Parallel hip Exoskeleton(Ph-Exo)in this ***-Exo is meticulously designed based on the anisotropic law of output *** the friction of the drive components,a dynamic model of the human-machine complex is *** analysis demonstrates that Ph-Exo not only exhibits outstanding torque performance but also achieves high controllability in both flexion/extension and adduction/abduction ***,a robust controller is designed to address model uncertainty,friction,and external *** experiments indicate that under the control of the robust controller,each motor achieves excellent tracking performance.

关键词： hip exoskeleton Parallel mechanism Misalignment Anisotropy Output torque

skeletal stem cells in bone development,homeostasis,and disease

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Protein & Cell 2024年第8期15卷 559-574页

作者： Guixin Yuan Xixi Lin Ying liu Matthew b.Greenblatt Ren xu The first Affliated hospital of Xiamen University-ICMRs Collaborating Center for skeletal stem Cell State Key Laboratory of Cellular Stress BiologySchool of MedicineFaculty of Medicine and Life SciencesXiamen UniversityXiamen 361005China Xiamen Key Laboratory of Regeneration Medicine Fujian Provincial Key Laboratory of Organ and Tissue RegenerationOrgan Transplantation InstituteSchool of MedicineXiamen UniversityXiamen 361102China Department of Pathology and Laboratory Medicine Weill Cormell Medical CollegeNew YorkNY 10065USA Research Division Hospital for Special SurgeryNew YorkNY10065USA

Tissue-resident stem cells are essential for development and repair,and in the skeleton,this function is fulfilled by recently identified skeletal stem cells(ssCs).however,recent work has identified that ssCs are not monolithic,with long bones,craniofacial sites,and the spine being formed by distinct stem *** studies have utilized techniques such as fluorescence-activated cell sorting,lineage tracing,and single-cell sequencing to investigate the involvement of ssCs in bone development,homeostasis,and *** investigations have allowed researchers to map the lineage commitment trajectory of ssCs in different parts of the body and at different time ***,recent studies have shed light on the characteristics of ssCs in both physiological and pathological *** review focuses on discussing the spatiotemporal distribution of ssCs and enhancing our understanding of the diversity and plasticity of ssCs by summarizing recent discoveries.

关键词： skeletal stem cells bone development endochondral ossification intramembranous ossification lineage tracing

strong hetero-interface interaction in 2D/2D Wse_(2)/ZnIn_(2)s_(4) heterostructures for highly-efficient photocatalytic hydrogen generation

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Journal of Energy Chemistry 2024年第10期97卷 379-387,I0008页

作者： xu Guo Xing liu jing shan Zhuo xu Zhiming fang Lu Wang shengzhong liu school of Energy Powerand Mechanical EngineeringNorth China Electric Power UniversityBeijing 102206China shaanxi Key Laboratory for Advanced Energy Devices School of Materials Science and EngineeringShanxi Normal UniversityXi'an 710119ShanxiChina Qinghai Advanced Energy storage Laboratory SPIC Qinghai Photovoltaic Industry Innovation Center Co.Ltd.State Power Investment CorporationXining 810oo7QinghaiChina Key Laboratory of Photoelectric Conversion and Utilization of solar Energy Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina Center of Materials science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

Green hydrogen is urgently required for sustainable development of human beings and rational construction of heterostructures holds great promising for photocatalytic hydrogen ***,2D/2D Wse_(2)/ZnIn_(2)s_(4) heterostructures with strong hetero-interface interaction and abundant contact were constructed via an impregnation-annealing *** charge transfer from ZnIn_(2)s_(4) to Wse_(2)was evidenced by transient absorption spectroscopy in crafted heterostructures owing to the tight and2D face-to-face *** a result,the prepared Wse_(2)/ZnIn_(2)s_(4) heterostructures exhibited boosted photocatalytic performance and a highest hydrogen evolution rate of 3.377 mmol/(g h)was achieved with an apparent quantum yield of 45.7%at 420 *** work not only provides new strategies to achieve efficient 2D/2D heterostructures but also paves the way for the development of green hydrogen in the future.

关键词： strong hetero-interface interaction in 2D/2D Wse_(2)/ZnIn_(2)s_(4) heterostructures for highly-efficient photocatalytic hydrogen generation

highly strong,Tough,and Cryogenically Adaptive hydrogel Ionic Conductors via Coordination Interactions

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Research 2024年第3期2024卷 703-713页

作者： Zhuomin Wang siheng Wang Lei Zhang he liu xu xu Institute of Chemical Industry of forestry Products Key Laboratory of Biomass Energy and MaterialJiangsu ProvinceKey Laboratory of Chemical Engineering of Forest ProductsNational Forestry and Grassland AdministrationNational Engineering Research Center of Low-Carbon Processing and Utilization of Forest BiomassJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest ResourcesChinese Academy of ForestryNanjing 210042China College of Chemical Engineering Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest ResourcesNanjing Forestry UniversityNanjing 210037China.

Despite the promise of high flexibility and conformability of hydrogel ionic conductors,existing polymeric conductive hydrogels have long suffered from compromises in mechanical,electrical,and cryoadaptive properties due to monotonous functional improvement strategies,leading to lingering ***,we propose an all-in-one strategy for the preparation of poly(acrylic acid)/cellulose(PAA/Cel)hydrogel ionic conductors in a facile yet effective manner combining acrylic acid and salt-dissolved cellulose,in which abundant zinc ions simultaneously form strong coordination interactions with the two polymers,while free solute salts contribute to ionic conductivity and bind water molecules to prevent ***,the developed PAA/Cel hydrogel simultaneously achieved excellent mechanical,conductive,and cryogenically adaptive properties,with performances of 42.5 MPa for compressive strength,1.6 MPa for tensile strength,896.9%for stretchability,9.2 MJ m^(−3)for toughness,59.5 kJ m^(−2)for fracture energy,and 13.9 and 6.2 ms cm^(−1)for ionic conductivity at 25 and−70°C,*** by these features,the resultant hydrogel ionic conductor is further demonstrated to be assembled as a self-powered electronic skin(e-skin)with high signal-to-noise ratio for use in monitoring movement and physiological signals regardless of cold temperatures,with hinting that could go beyond high-performance hydrogel ionic conductors.

关键词： highly freezing salts

Atomically precise Ru-O-Ru clusters for enhanced water dissociation in alkaline hydrogen evolution

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Nano Research 2024年第8期17卷 6993-7000页

作者： Dong liu Li xu sicheng Li Airong xu Yuanhua sun Tong liu Mengyuan liu huijuan Wang Xiaokang liu Tao Yao Tao Ding hefei National Research Center for Physical sciences at the Microscale School of Nuclear Science and TechnologyKey Laboratory of Precision and Intelligent ChemistryNational Synchrotron Radiation LaboratoryUniversity of Science and Technology of ChinaHefei 230029China Experimental Center of Engineering and Materials science University of Science and Technology of ChinaHefei 230026China

Atomic clusters typically exhibit distinctive electronic structures and physicochemical ***,as the size decreases,their ability to adsorb and dissociate water also diminishes,thereby affecting chemical reactions involving water *** the adsorption and dissociation capabilities of atomic clusters towards water molecules and elucidating the mechanisms underlying their performance enhancement have become important research ***,employing the carrier-anchored strategy,Ru-O-Ru atomic clusters were prepared and displayed excellent activity and durability in the hydrogen evolution ***,the Ru-O-Ru atomic clusters exhibited only 86 mV overpotential at 100 mA·cm−^(2) and superior membrane-electrode-assembly activity than commercial Ru/C *** radiation-based fourier transform infrared spectroscopic measurements revealed that the modification of oxygen in Ru-O-Ru units promoted the reorientation of water molecules from a h-up orientation to h-down,therefore,enhanced the formation of strong hydrogen-bond network of interfacial water on the surface of Ru-O-Ru clusters,leading to enhanced adsorption and dissociation of water and accelerated Volmer *** findings provide a potential strategy and deep insights for the development of atomic clusters in electrocatalysts.

关键词： hydrogen evolution in-situ fourier transform infrared(fTIR) Ru catalysts electrocatalysis atomic clusters

W-band millimeter wave vialess microstrip-to-microstrip vertical transition in multilayer LCP substrate

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The Journal of China Universities of Posts and Telecommunications 2024年第3期31卷 87-94页

作者： liu Weihong Zhang xu Guan Dongyang school of Electronic Engineering Xian University of Posts and TelecommunicationsXi'an 710121China

In this paper,a W-band broadband vialess microstrip(Ms)-to-Ms vertical transition in multilayer liquid crystal polymer(LCP)substrate is presented,which consists of two Ms lines in the top layer,a common ground plane and slotline resonators in the second layer,and a close-loop transmission-line in the third *** increase the passband of the vialess vertical transition,an h-shaped slotline resonator is introduced,which greatly improves the impedance performance of the slotline resonator,and the full-wave simulated results indicate that insertion loss(IL)is less than 2 db and return loss(RL)is better than 10 db at *** verify this design,the broadband vertical transition is fabricated and *** measured results indicate that a broadband vertical transition with RL better than 10 db and IL less than 5.67 db can be obtained in the frequency range from 70.00 Ghz to 104.09 *** to the fabrication error in the preparation process,the measured results are deteriorated compared to the simulated results,and the investigation indicates that the deviation is caused by the thickness error of the LCP substrate.

关键词： W-band broadband microstrip(Ms)-to-Ms vialess vertical transition liquid crystal polymer(LCP)

Revealing the role of honokiol in human glioma cells by RNA-seq analysis

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bIOCELL 2024年第6期48卷 945-958页

作者： YUNbAO GUO xu liu QI xu XIAOTONG ZhOU JIAWEI liu YANYAN xu YAN LU hAIYAN liu The Department of Neurosurgery First Hospital of Jilin UniversityChangchun130021China The Department of Anatomy College of Basic Medical SciencesJilin UniversityChangchun130021China The Third College of Clinical Medicine Jilin UniversityChangchun130021China

background:Glioma is a kind of tumor that easily deteriorates and originates from glial cells in nerve *** is a bisphenol compound that is an essential monomeric compound extracted from the roots and bark of Magnoliaceae *** also has anti-infection,antitumor,and immunomodulatory *** this study,we found that honokiol induces cell apoptosis in the human glioma cell lines U87-MG and ***,the mechanism through which honokiol regulates glioma cell apoptosis is still ***:We performed RNA-seq analysis of U251-MG cells treated with honokiol and control ***-protein interaction(PPI)network analysis was performed,and the 10 top hub unigenes were examined via real-time quantitative ***,MAPK signaling and ferroptosis were detected via western ***:332 differentially expressed genes(DEGs)were found,comprising 163 increased and 169 decreased *** of the DEGs revealed that various biological processes were enriched,including‘response to hypoxia’,‘cerebellum development cellular response to hypoxia,’‘iron ion binding,’‘oxygen transporter activity,’‘oxygen binding,’‘ferric iron binding,’and‘structural constituent of cytoskeleton.’Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis revealed that the DEGs were enriched in the following pathways:‘mitogen-activated protein kinases(MAPK)’,‘hypoxia-inducible factor 1(hIf-1)’,‘ferroptosis,’‘Peroxisome proliferator-activated receptor(PPAR),’‘Phosphatidylinositol-4,5-bisphosphate 3-kinase(PI3K)-protein kinase b(Akt),’and‘phagosome.’Among these pathways,the MAPK signaling pathway and ferroptosis were veriﬁ***:This study revealed the potential mechanism by which honokiol induces apoptosis and provided a comprehensive analysis of DEGs in honokiol-treated U251-MG cells and the associated signaling *** data could lead to new ideas for future research and therapy for patients with glioma.

关键词： human glioma honokiol RNA-seq Apoptosis ferroptosis MAPK

Effect of hot isostatic pressure on the microstructure and tensile properties of γ'-strengthened superalloy fabricated through induction-assisted directed energy deposition

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International Journal of Minerals,Metallurgy and Materials 2024年第5期31卷 1089-1097页

作者： Jianjun xu hanlin Ding Xin Lin feng liu Analytical&Testing Center Northwestern Polytechnical UniversityXi’an 710072China state Key Laboratory of solidification Processing Northwestern Polytechnical UniversityXi’an 710072China

The microstructure characteristics and strengthening mechanism of Inconel738LC(IN-738LC) alloy prepared by using induction-assisted directed energy deposition(IDED) were elucidated through the investigation of samples subjected to IDED under 1050℃ preheating with and without hot isostatic pressing(hIP,1190℃,105 MPa,and 3 h).Results show that the as-deposited sample mainly consisted of epitaxial columnar crystals and inhomogeneously distributed γ’ phases in interdendritic and dendritic core *** hIP,grain morphology changed negligibly,whereas the size of the γ’ phase became increasingly *** further heat treatment(hT,1070℃,2 h + 845℃,24 h),the γ’ phase in the as-deposited and hIPed samples presented a bimodal size distribution,whereas that in the as-deposited sample showed a size that remained *** comparison of tensile properties revealed that the tensile strength and uniform elongation of the hIP + hTed sample increased by 5% and 46%,respectively,due to the synergistic deformation of bimodal γ’phases,especially large cubic γ’ ***,the relationship between phase transformations and plastic deformations in the IDEDed sample was discussed on the basis of generalized stability theory in terms of the trade-off between thermodynamics and kinetics.

关键词： directed energy deposition Ni-based superalloys high-temperature preheating hot isostatic pressing microstructure tensile properties

Electron kinetic effects in back-stimulated Raman scattering bursts driven by broadband laser pulses

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Matter and Radiation at Extremes 2024年第4期9卷 54-67页

作者： Q.K.liu L.Deng Q.Wang X.Zhang f.Q.Meng Y.P.Wang Y.Q.Gao h.b.Cai s.P.Zhu Graduate school China Academy of Engineering PhysicsBeijing 100088China Institute of Applied Physics and Computational Mathematics Beijing 100094China school of Nuclear science and Technology University of Science and Technology of ChinaHefei 230026China shanghai Institute of Laser Plasma Shanghai 201800China hEDPs Center for Applied Physics and TechnologyPeking UniversityBeijing 100871China school of Physics Zhejiang UniversityHangzhou 310027China

We examine electron kinetic effects in broadband-laser-driven back-stimulated Raman scattering(bsRs)bursts using particle-in-cell *** bursts occur during the nonlinear stage,causing reflectivity spikes and generating large numbers of hot ***-duration simulations are performed to observe burst events,and a simplified model is developed to eliminate the interference of the broadband laser’s random intensity *** the simplified model,we isolate and characterize the spectrum of electron plasma *** spectrum changes from a sideband structure to a turbulence-like structure during the burst.A significant asymmetry in the spectrum is *** asymmetry is amplified and transferred to electron phase space by high-intensity broadband laser pulses,leading to violent vortex-merging and generation of hot *** proportion of hot electrons increases from 6.76%to 14.7%during a single violent burst *** demonstrate that kinetic effects profoundly influence the bsRs evolution driven by broadband lasers.

关键词： scattering kinetic simplified