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Convergent plate boundary environments f.r f.rmation of≥3800 Ma mafic-ultramafic assemblages(Isua area,Greenland):Implications f.r early global geodynamics

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Geoscience frontiers 2024年第3期15卷 119-136页

作者： Allen P.Nutman Clark r.L.friend Vickie C.Bennett School of Earth Atmospheric and Life SciencesUniversity of WollongongWollongongNSW 2522Australia Glendale TiddingtonOxon OX92LQUK research School of Earth Sciences Australian National UniversityCanberraACT 2601Australia

In the gneiss terrane on the south side of the Eoarchean Isua supracrustal belt,ultramafic rocks with relict abyssal peridotite mineralogy(Bennett et al.,2002;friend et al.,2002;Nutman et al.,2007;rollinson,2007;van de Löcht et al.,2020),layered gabbros with cumulate ultramafic rocks,basalts and associated siliceous sedimentary rocks were tectonically-imbricated,prior to and during intrusion of ca.3800 Ma *** with3800 Ma basalts in the Outer Arc group of the nearby Isua supracrustal belt,the composition of all these mafic rocks(e.g.,Th-Hf-Nb systematics,high Th/Yb,Ba/Nb,Ba/Yb ratios and negative Nb and Ti anomalies)shows affinity with modern suprasubduction rocks whose genesis involved fluid fluxing of the upper ***,the majority of these samples have Ba/Nb and Ba/Yb values less than in modern island arc magmas,but similar to many backarc basin magmas(e.g.,Pearce and Stern,2006).It is unknown whether these ca.3800 Ma mafic rocks are,(i)arc rocks where the Ba/Nb and Ba/Yb signatures reflect lower surficial Ba in Eoarchean oceanic settings,or(ii)in direct comparison with Phanerozoic suites,these signatures reflect a back-arc setting with interplay between fluid fluxing and decompressional *** tectonic intercalation of upper mantle with lower and upper crustal rocks,combined with the fluid-fluxing influences seen in chemistry of all the mafic rocks is best accommodated in a compressional Eoarchean convergent plate boundary setting within a mobile-lid *** stagnant lid scenarios of crust f.rmation,if operative,must have co-existed or alternated with mobile-lid regimes by 3800 Ma.

关键词： Eoarchean fluid-fluxing Plate tectonics Suprasubduction Crustal evolution

In-situ construction of grass-like hybrid architecture responsible f.r extraordinary corrosion perf.rmance: Experimental and theoretical approach

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Nano Materials Science 2024年第1期6卷 44-59页

作者： T.Suhartono f.Hazmatulhaq Y.Sheng A.Chaouiki M.P.Kamil Y.G.Ko Materials Electrochemistry group School of Materials Science and EngineeringYeungnam UniversityGyeongsan38541Republic of Korea research Center f.r Advanced Materials National Research and Innovation Agency(BRIN)South TangerangBanten15314Indonesia

Despite the engineering potential by the co-existence of inorganic and organic substances to protect vulnerable metallic materials from corrosive environments,both their interaction and in-situ f.rmation mechanism to induce the nature-inspired composite remained less *** present work used three distinctive mercaptobenzazole(MB)compounds working as corrosion inhibitors,such as 2-mercaptobenzoxazole(MBO),2-mercaptobenzothiazole(MBT),and 2-mercaptobenzimidazole(MBI)in a bid to understand how the geometrical structure arising from O,S,and N atoms affected the interaction toward inorganic *** compounds that were used here to control the corrosion kinetics would be interacted readily with the pre-existing MgO layer fabricated by plasma *** phenomenon triggered the nucleation of the root network since MB compounds were seen to be adsorbed actively on the defective surface through the active sites in MB ***,the molecule with twin donor atoms adjacent to the mercapto-sites affected the facile growth of the grass-like structures with‘unif.rm’distribution via molecular self-assembly,which showed better corrosion perf.rmance than those with having dissimilar donor atoms with the inhibition efficiency(η)of 97%*** f.rmation mechanism underlying nucleation and growth behavior of MB molecule was discussed concerning the theoretical calculation of density functional theory.

关键词： Nature-inspired composite Organic-inorganic interaction Corrosion inhibitor Density functional theory Electrochemistry

Associations of polygenic risk scores with risks of stroke and its subtypes in Chinese

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Stroke & Vascular Neurology 2024年第4期9卷 399-406,I0044-I0065页

作者： Songchun Yang Zhijia Sun Dong Sun Canqing Yu Yu Guo Dianjianyi Sun Yuanjie Pang Pei Pei Ling Yang Iona Y Millwood robin G Walters Yiping Chen Huaidong Du Yan Lu Sushila Burgess Daniel Avery robert Clarke Junshi Chen Zhengming Chen Liming Li Jun Lv On behalf of the China Kadoorie Biobank Collaborative group Department of Epidemiology&Biostatistics School of Public HealthPeking UniversityBeijingChina Department of Dermatology Xiangya HospitalCentral South UniversityChangshaHunanChina Peking University Center f.r Public Health and Epidemic Preparedness&response BeijingChina Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijingChina fuwai Hospital Chinese Academy of Medical Sciences BeijingChina Medical research Council Population Health research Unit at the University of Oxf.rd OxfordUK Clinical Trial Service Unit&Epidemiological Studies Unit(CTSU) Nuffield Department of Population HealthUniversity of OxfordOxfordUK NCDs Prevention and Control Department Suzhou CDCSuzhouJiangsuChina China National Center f.r food Safety risk Assessment BeijingChina State Key Laboratory of Vascular Homeostasis and remodeling Peking UniversityBeijingChina 不详

Background and purpose Previous studies,mostly focusing on the European population,have reported polygenic risk scores(PrSs)might achieve risk stratification of *** aimed to examine the association strengths of PrSs with risks of stroke and its subtypes in the Chinese *** Participants with genome-wide genotypic data in China Kadoorie Biobank were split into a potential training set(n=22191)and a population-based testing set(n=72150).four previously developed PrSs were included,and new PrSs f.r stroke and its subtypes were *** PrSs showing the strongest association with risks of stroke or its subtypes in the training set were f.rther evaluated in the testing *** proportional hazards regression models were used to estimate the association strengths of diff.rent PrSs with risks of stroke and its subtypes(ischaemic stroke(IS),intracerebral haemorrhage(ICH)and subarachnoid haemorrhage(SAH)).results In the testing set,during 872919 person-years of follow-up,8514 incident stroke events were *** PrSs of any stroke(AS)and IS were both positively associated with risks of AS,IS and ICH(pr f.r per SD increment(Hr_(SD))of PrSAS was 1.10(95%CI 1.07 to 1.12),1.10(95%CI 1.07 to 1.12)and 1.13(95%CI 1.07 to 1.20)f.r AS,IS and ICH,*** corresponding Hr_(SD) of PrS_(IS) was 1.08(95%CI 1.06 to 1.11),1.08(95%CI 1.06 to 1.11)and 1.09(95%CI 1.03 to 1.15).PrS_(ICH) was positively associated with the risk of ICH(Hr_(SD)=1.07,95%CI 1.01 to 1.14).PrSS_(AH) was not associated with risks of stroke and its *** addition of current PrSs off.red little to no improvement in stroke risk prediction and risk *** In this Chinese population,the association strengths of current PrSs with risks of stroke and its subtypes were moderate,suggesting a limited value f.r improving risk prediction over traditional risk factors in the context of current genome-wide association study under-representing the East Asia

关键词： testing prediction increment

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国家高山滑雪中心,北京,中国

世界建筑 2024年第4期 24-25页

作者： China Architecture Design&research group 中国建筑设计研究院有限公司

作为国内第一座按冬奥赛事标准建设的高山滑雪场馆,国家高山滑雪中心承办了北京2022年冬奥会和冬残奥会高山滑雪项目比赛。场馆用地范围432.4hm^(2),场地落差960m。场馆内各类雪道总长度23.1km,围绕雪道规划形成四大主要建设区域,建筑面... 详细信息

作为国内第一座按冬奥赛事标准建设的高山滑雪场馆,国家高山滑雪中心承办了北京2022年冬奥会和冬残奥会高山滑雪项目比赛。场馆用地范围432.4hm^(2),场地落差960m。场馆内各类雪道总长度23.1km,围绕雪道规划形成四大主要建设区域,建筑面积43,200m^(2)。

关键词：高山滑雪用地范围残奥会场馆

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弘扬教育家精神照亮千万孩子的梦想

中小学校长 2024年第4期 15-19页

作者： Educationalist Spirit Touring Lecture group 2024 教育家精神2024年巡回宣讲团

教育部党组书记、部长怀进鹏在十四届全国人大二次会议民生主题记者会上强调,建设高质量教育体系,必须依靠有爱的温度的高水平教师队伍。我们要大力弘扬教育家精神,引导教师成长为有情怀、有水平、有温度的好老师,照亮千万孩子的梦想。... 详细信息

教育部党组书记、部长怀进鹏在十四届全国人大二次会议民生主题记者会上强调,建设高质量教育体系,必须依靠有爱的温度的高水平教师队伍。我们要大力弘扬教育家精神,引导教师成长为有情怀、有水平、有温度的好老师,照亮千万孩子的梦想。教育家精神2024年巡回宣讲活动,以最质朴的事例,讲述一个个有爱的温度的教育故事,生动诠释教育家精神。在教育部教师工作司的指导下,本期选登基础教育领域的全国教书育人楷模、全国最美教师等优秀教师代表的鲜活案例,以期进一步唤起更多人热爱教育、理解教育、支持教育,做教育家精神的传播者和实践者。

关键词：教育家精神基础教育领域高质量教育教书育人热爱教育教育部党组优秀教师最美教师

Chinese expert consensus on the clinical application of sodium-glucose cotransporter 2 inhibitors in patients with chronic kidney disease

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Chinese Medical Journal 2024年第11期137卷 1264-1266页

作者： The Expert group of Chinese Expert Consensus on the Clinical Application of Sodium-glucose Cotransporter 2 Inhibitors in Patients with Chronic Kidney Disease fan fan Hou Chuanming Hao Min Zhang Chuanming Hao 不详 Department of Nephrology Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong 510515China Division of Nephrology Huashan HospitalFudan UniversityShanghai 200040China

The prevalence of chronic kidney disease(CKD)in China was 8.2%in 2018-2019.[1]CKD may progress to end-stage kidney disease(ESKD),necessitating kidney replacement treatment such as dialysis or kidney transplantation,[2]which imposes a substantial burden on both family and ***,patients with CKD have a high risk of comorbidities including cardiovascular diseases.[3]The risk of death rises as the estimated glomerularltration rate(eGfr)declines.[3]A substantial portion of CKD patients die,primarily from cardiovascular events,bef.re reaching the stage requiring dialysis.[3]As such,delaying the progression of CKD and reducing cardiovascular events are key elements in patient *** recent years,important progress has been made in the cardiorenal protection of patients with ***cally,the advent of sodium-glucose cotransporter 2(SGLT2)inhibitors has provided a new and important approach f.r the treatment of CKD.

关键词： kidney patients dialysis

functional mechanism study of the allelochemical myrigalone A identifies a group of ultrapotent inhibitors of ethylene biosynthesis in plants

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Plant Communications 2024年第6期5卷 246-262页

作者： George Heslop-Harrison Kazumi Nakabayashi Ana Espinosa-ruiz francesca robertson robert Baines Christopher r.L.Thompson Katrin Hermann David Alabadí Gerhard Leubner-Metzger robin S.B.Williams Centre f.r Biomedical Sciences Department of Biological SciencesRoyal Holloway University of LondonEgham TW200EXUK Centre f.r Plant Molecular Sciences Department of Biological SciencesRoyal Holloway University of LondonEgham TW200EXUK Instituto de Biología Molecular y Celular de Plantas(CSIC-UPV) 46022 ValenciaSpain Centre f.r Life’s Origins and Evolution Department of GeneticsEvolution and EnvironmentUniversity College LondonLondonUK Syngenta Crop Protection AGSteinSwitzerland

Allelochemicals represent a class of natural products released by plants as root,leaf,and fruit exudates that interf.re with the growth and survival of neighboring *** how allelochemicals function to regulate plant responses may provide valuable new approaches to better control plant *** such allelochemical,Myrigalone A(MyA)produced by Myrica gale,inhibits seed germination and seedling growth through an unknown ***,we investigate MyA using the tractable modelDictyostelium discoideum and reveal that its activity depends on the conserved homolog of the plant ethylenesynthesis protein 1-aminocyclopropane-1-carboxylic acid oxidase(ACO).f.rthermore,in silico modeling predicts the direct binding of MyA to ACO within the catalytic *** ***,ablation of ACO mimics the MyA-dependent developmental delay,which is partially restored by exogenous ethylene,and MyA reduces ethylene *** Arabidopsis thaliana,MyA treatment delays seed germination,and this effect is rescued by exogenous *** also mimics the effect of established ACO inhibitors on root and hypocotyl extension,blocks ethylenedependent root hair production,and reduces ethylene ***,in silico binding analyses identify a rangeof highlypotentethylene inhibitorsthatblock ethylene-dependent responseand reduce ethyleneproduction in ***,we demonstrate a molecular mechanism by which the allelochemical MyA reduces ethylene biosynthesis and identify a range of ultrapotent inhibitors of ethylene-regulated responses.

关键词： 1-aminocyclopropane-1-carboxylic acid ACC ACC oxidase ACO allelochemicals ethylene synthesis inhibitors structure-activity relationship

IVf成功定义—基于Delphi法的中国专家意见

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中华生殖与避孕杂志 2024年第9期44卷 887-897页

作者： IVf成功定义专家组李蓉不详北京大学第三医院妇产科北京100191

目的旨在采用Delphi法对体外受精(in vitro f.rtilization, IVf)成功的定义提出专家意见, 为临床实践提供参考依据。方法采用Delphi法对衡量IVf成功定义进行专家调查, 由8名专家基于相关文献制定陈述框架, 并通过会议讨论细化陈述内容,... 详细信息

目的旨在采用Delphi法对体外受精(in vitro f.rtilization, IVf)成功的定义提出专家意见, 为临床实践提供参考依据。方法采用Delphi法对衡量IVf成功定义进行专家调查, 由8名专家基于相关文献制定陈述框架, 并通过会议讨论细化陈述内容, 形成陈述初始内容。通过发放调研问卷, 就陈述内容征询23名生殖专家意见。据专家反馈意见对陈述进行修改, 并再次发放问卷, 直至达成共识。结果共进行2轮问卷调查, 专家参与的积极程度分别为100%(23/23)和73.9%(17/23), 专家权威系数为0.895。就IVf成功定义相关的19条陈述达成共识, 主要包括:①IVf治疗的目标(1条陈述), 即安全地尽快获得单胎健康活产。②IVf成功的定义(13条陈述), 包括IVf治疗的有效性、安全性和效率的评估, 单个卵巢刺激周期2年内的累积活产率是衡量IVf治疗成功的绩效指标。衡量IVf成功应从以患者为中心角度出发, 结合患者的负担和满意度进行评价。③IVf成功的保障(3条陈述)。IVf治疗应遵循循证医学证据, 尽量避免在诊疗过程中实施未经证实的、患者获益不明确的治疗方案。辅助生殖机构应通过建立关键技术指标的监测并完善质控体系来优化治疗质量。④IVf成功的挑战(2条陈述)。取卵前取消周期和治疗周期失败后放弃继续治疗是IVf成功不可忽视的挑战。结论基于Delphi法, 结合生殖专家组的临床观点, 就IVf成功的定义形成了专家意见, 可作为临床指南的补充, 用于指导临床实践, 助力改善治疗结局。

关键词：受精,体外成功率累积活产率

Effectiveness of craniosacral therapy,Bowen therapy,static touch and standard exercise program on sleep quality in fibromyalgia syndrome:A randomized controlled trial

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Journal of Integrative Medicine 2024年第4期22卷 473-483页

作者： reepa Avichal Ughreja Prem Venkatesan Dharmanand Balebail Gopalakrishna Yogesh Preet Singh Vani Lakshmi r Department of Physiotherapy Manipal College of Health ProfessionsManipal Academy of Higher EducationManipal 576104KarnatakaIndia Department of.rheumatology Manipal HospitalBengaluru 560052KarnatakaIndia Department of Clinical Immunology and rheumatology All India Institute of Medical SciencesBilaspur 174001Himachal PradeshIndia Department of Data Science Prasanna School of Public HealthManipal Academy of Higher EducationManipal 576104KarnatakaIndia

Background:Sleep disturbance is commonly seen in fibromyalgia syndrome (fMS);however,high quality studies involving manual therapies that target fMS-linked poor sleep quality are lacking f.r the Indian ***:Craniosacral therapy (CST),Bowen therapy and exercises have been found to influence the autonomic nervous system,which plays a crucial role in sleep *** the paucity of evidence concerning these effects in individuals with fMS,our study tests the effectiveness of CST,Bowen therapy and a standard exercise program against static touch (the manual placebo group) on sleep quality in ***,setting,participants and intervention:A placebo-controlled randomized trial was conducted on132 fMS participants with poor sleep at a hospital in *** participants were randomly allocated to one of the four study groups,including CST,Bowen therapy,standard exercise program,and a manual placebo control group that received static ***,Bowen therapy and static touch treatments were administered in once-weekly 45-minute sessions f.r 12 weeks;the standard exercise group received weekly supervised exercises f.r 6 weeks with home exercises until 12 *** 12 weeks,all study participants perf.rmed the standard exercises at home f.r another 12 *** outcome measures:Sleep quality,pressure pain threshold (PPT),quality of life and fibromyalgia impact,physical function,fatigue,pain catastrophizing,kinesiophobia,and positive–negative affect were recorded at baseline,and at weeks 12 and 24 of the ***:At the end of 12 weeks,the sleep quality improved significantly in the CST group (P=0.037) and Bowen therapy group (P=0.023),and the PPT improved significantly in the Bowen therapy group(P=0.002) and the standard exercise group (Pred to the static touch *** improvements were maintained at 24 *** between-group diff.rences were observed f.r other secondary ***:CST and Bowen therapy improv

关键词： Chronic pain Complementary therapies Exercise fibromyalgia Musculoskeletal manipulations Sleep