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Vigorous,but differential mononuclear cell response of cirrhotic patients to bacterial ligands

World Journal of Gastroenterology 2011年第10期17卷 1317-1325页

作者： Varenka J Barbero-Becerra María Concepción Gutiérrez-Ruiz Carmen Maldonado-Bernal f.lix i téllez-avila Roberto Alfaro-Lara florencia Vargas-Vorácková Department of Gastroenterology Instituto Nacional de Ciencias Médicasy Nutrición Salvador Zubirán Laboratorio de fisiología Celular División de Ciencias de la Salud Universidad Autónoma Metropolitana-Iztapalapa Unidad de investigación Médica en Enfermedades infecciosasy Parasitarias Hospital de Pediatría Unidad de investigación en Enfermedades Oncológicas Hospital Infantil de México Federico Gómez

AiM: to study the role of gram-positive and gram-negative bacteria in the pathogenesis of liver injury, specifically the activation of inflammatory mediators. MEtHODS: Peripheral blood mononuclear cells of 20 out-patients were studied, 10 of them with *** blood mononuclear cells were isolated and exposed to lipopolysaccharide or lipoteichoic acid. CD14, toll-like receptor 2 and 4 expression was determined by flow cytometry, and tumor necrosis factor (tNf) α, interleukin (iL)-1β, iL-6, iL-12 and iL-10 secretion in supernatants was determined by ELiSA. RESULtS: Higher CD14, toll-like receptor 2 and 4 expression was observed in peripheral blood mononuclear cells from cirrhotic patients, (P tively. Lipopolysaccharide and lipoteichoic acid induced a further increase in CD14 expression (P ipopolysaccharide, P ipoteichoic acid), and a decrease in toll-like receptor 2 (P ipopolysaccharide, P ipoteichoic acid) and toll-like receptor 4 (P ipopolysaccharide, P ipoteichoic acid) expression. With the exception of tNfα, absolute cytokine secretion of peripheral blood mononuclear cells was lower in cirrhotic patients under nonexposure conditions (P iL-6, P iL-1β, P iL-12). Once exposed to lipopolysaccharide or lipoteichoic acid, absolute cytokine secretion of peripheral blood mononuclear cells was similar in cirrhotic and non-cirrhotic patients, determining a more vigorous response in the former (P tNfα, iL-1β, iL-6, iL-2 and iL-10 lipopolysaccharide; P tNfα; P iL-1β; P iL-6; P iL-12; P iL-10 lipoteichoic acid). Response of peripheral blood mononuclear cells was more intense after lipopolysaccharide than after lipoteichoic acid exposure. CONCLUSiON: Peripheral blood mononuclear cells of cirrhotic patients are able to respond to a sudden bacterial ligand exposure, particularly lipopolysaccharide, suggestin

关键词：单核细胞肝硬化细菌性患者外周血单个核细胞 toll样受体4 配体肿瘤坏死因子

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Biomimetic Control of Mechanical Systems Equipped with Musculotendon Actuators

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Journal of Bionic Engineering 2011年第1期8卷 56-68页

作者： Javicr Moreno-Valenzuel Adriana Salinas-avila instituto Politecnico Naoional-CitEDl Av. del Parque 1310 Mesa de Otay Tianjuana B.C. 22510 Mexico

this paper addresses the problem of modelling, control, and simulation of a mechanical system actuated by an agonist-antagonist musculotendon subsystem. Contraction dynamics is given by case 1 of Zajac＇s model. Saturated semi positive proportional-derivative-type controllers with switching as neural excitation inputs are proposed. Stability theory of switched system and SOStOOLS, which is a sum of squares optimization toolbox of Matlab, are used to determine the stability of the obtained closed-loop system. to corroborate the obtained theoretical results numerical simulations are carried out. As additional contribution, the discussed ideas are applied to the biomimetic control of a DC motor, i.e., the position control is addressed assuming the presence of musculotendon actuators. Real-experiments corroborate the expected results.

关键词： biomimetie control musculotendon dynamics neural excitation saturation switched systems

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A comparative assessment of empirical and lattice Boltzmann method-based drag models for simulation of gas-solid flow hydrodynamics in a bubbling fluidized bed

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Particuology 2017年第4期15卷 129-137页

作者： Carlos M. Romero Luna Luis R. Carrocci Gretta L.A.f. Arce ivonete avila UNESP - Sflo Paulo State University School of Engineering Department of Energy Laboratory of Combustion and Carbon Capture (LC3) CEP 12.516-410 Guaratinguetd SP Brazil iNPE - Brazilian Space Research institute Combustion and Propulsion Associated I.aboratory CEP 12.630-000 Cachoeira Paulista SP Brazil UNJfSC -Jose faustino Sanchez Carrion National University Faculty of Chemical and Metallurgical Engineering Advanced Materials and Nanotechnology Research Group Huacho Lima Peru

in simulations of fluidized beds using computational fluid dynamics （CfD）, the description of gas-solid flow hydrodynamics relies on a drag model to account for the momentum transfer between gas and solid phases. Although several studies of drag models have been published, there have been few investigations of the application of lattice Boltzmann method （LBM）-based drag models to bubbling fluidized bed simu- lations. in the present study, a comprehensive comparison of empirical and LBM-based drag models was carried out to assess the performance of these models during simulations of gas-solid flow hydrodynam- ics in a bubbling fluidized bed. A CfD model using the MfiX code based on the Eulerian-Eulerian approach and the kinetic theory of granular flow was used to simulate a 2D bubbling fluidized bed with Geldart B particles. the simulation results were validated by comparison with experimental data. Statistical anal- ysis of the results shows that LBM-based drag models can reliably model gas-solid flow hydrodynamics in a bubbling fluidized bed.

关键词： CfD Drag model Gas-solid flow hydrodynamics Bubbling fluidized bed

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Quantum information entropies of the eigenstates for the Pschl-teller-like potential

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Chinese Physics B 2013年第5期22卷 113-117页

作者： Guo-Hua Sun M. avila Aoki Shi-Hai Dong Centro Universitario Valle de Chalco Universidad Autónoma del Estado de México Departamento de física Escuela Superior de Física y MatemáticsInstituto Politécnico Nacional

Shannon entropy for lower position and momentum eigenstates of Ptschl-teller-like potential is evaluated. Based on the entropy densities demonstrated graphically, we note that the wave through of the position information entropy density p （x） moves right when the potential parameter V1 increases and its amplitude decreases. However, its wave through moves left with the increase in the potential parameter 丨V2丨. Concerning the momentum information entropy density p（p）, we observe that its amplitude increases with increasing potential parameter V1, but its amplitude decreases with increasing丨V2丨. the Bialynicki-Birula-Mycielski （BBM） inequality has also been tested for a number of states. Moreover, there exist eigenstates that exhibit squeezing in the momentum information entropy. finally, we note that position information entropy increases with V1, but decreases with 丨V2丨, However, the variation of momentum information entropy is contrary to that of the position information entropy.

关键词： bound states quantum information entropy Poschl-teller-like potential

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Primary Characterization of a Novel Soymilk-Cashew fermented with an improving of its Antioxidant and Anti-inflammatory Contents

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food and Nutrition Sciences 2023年第5期14卷 421-435页

作者： Assamoi A. Antoine Atobla Koua Ouattara H. Djeneba Gnagnini tokro Ruth D’avila Unité Pédagogique et de Recherches en Biotechnologies Laboratoire de Biotechnologies Agriculture et Valorisation des Ressources Biologiques UFR Biosciences Université Félix Houphou&#235t-Boigny Faculté des Sciences Biologiques Université Félix Houphouet-Boigny Abidjan C&#246te d’Ivoire

Cashew nut (Anacardium occidental) milk was included as a functional ingredient in soybean (Glycine max L.) milk at 20/80% and was fermented comparatively to commercial yogurt starters by two strains tC6 and A4 (recently isolated from two ivorian highly flavored neglected traditional staple foods (beer and garlic)) identified as Weissella paramesenteroides and Enterococcus faecalis, after the screening of their probiotic, antioxydant and anti-inflammatory potentialities, respectively. the primary characterization of these plant-milks showed a strong improvement in their sensory, antioxidant and anti-inflammatory abilities. While tC6 from traditional beer tchapalo increases anti-inflammatory activity by almost eighteen times, A4 isolated from garlic increases antioxidant activity by two times. Due to their aromatic and organosensory potentialities certainly, milks L138, L180 and 130 fermented respectively by the combination of tC6 and A4, tC4 alone and A4 alone were the most appreciated than the plant-milk fermented by the two strains of commercial yogurt. these probiotics, anti-oxidant and anti-inflammatory plant-milks should be further characterized in terms of their biological activities and tested in animal models to confirm their nutrition-health claims.

关键词： Probiotic Staple food Soy-Milk Anti-Oxydant Anti-inflammatory

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Precipitation analysis of as-cast HK40 steel after isothermal aging

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international Journal of Minerals,Metallurgy and Materials 2017年第10期24卷 1125-1133页

作者： M.L. Saucedo-Munoz A. Ortiz-Mariscal V.M. Lopez-Hirata J.D. Villegas-Cardenas Orlando Soriano-Vargas Erika O. avila-Davila instituto Politecnico Nacional (ESiQiE) Apdo. Postal 118-395 Mexico D.F. 07300 Universidad Politecnica Metepec y Tultitlan Edo. Mex. Mexico tecnológico de Estudios Superiores de Jocotitlan Jocotitlan Edo. Mex. Mexico

As-cast HK40 steel was aged at 700, 800, or 900℃ for times as long as 2000 h. Microstructural characterization showed that the primary M_7C_3 carbide network contained a substantial content of manganese, in agreement with the microsegregation of manganese calculated by thermo-Calc using the Scheil–Gulliver module. the dissolution of primary carbides caused the solute supersaturation of austenite and subsequent precipitation of fine M_(23)C_6 carbides in the austenite matrix for aged specimens. During prolonged aging, the carbide size increased with increasing time because of the coarsening process. A time–temperature–precipitation diagram for M_(23)C_6 carbides was calculated using the thermo-CalcPRiSMA software; this diagram showed good agreement with the experimental growth kinetics of precipitation. the fine carbide precipitation caused an increase in hardness; however, the coarsening process of carbides promoted a decrease in hardness. Nanoindentation tests of the austenite matrix indicated an increase in ductility with increasing aging time.

关键词： as-cast HK40 steel carbide precipitation aging precipitation simulation

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R&D of back-end electronics for improved resistive plate chambers for the phase 2 upgrade of the CMS end-capmuon system

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Radiation Detection technology and Methods 2022年第3期6卷 306-316页

作者： H.Kou Z.-A.Liu J.Zhao J.Song Q.Hou W.Diao P.Cao W.Gong N.Wang A.Samalan M.tytgat M.El Sawy G.A.Alves f.Marujo E.A.Coelho f.torres Da Silva De Araujo E.M.Da Costa H.Nogima A.Santoro S.fonseca De Souza D.De Jesus Damiao M.thiel M.Barroso ferreira filho K.Mota Amarilo A.Aleksandrov R.Hadjiiska P.iaydjiev M.Rodozov M.Shopova G.Sultanov A.Dimitrov L.Litov B.Pavlov P.Petkov A.Petrov E.Shumka S.J.Qian C.avila D.Barbosa A.Cabrera A.florez J.fraga J.Reyes Y.Assran M.A.Mahmoud Y.Mohammed i.Laktineh G.Grenier M.Gouzevitch L.Mirabito K.Shchablo C.Combaret W.tromeur G.Galbit A.Luciol X.Chen i.Bagaturia i.Lomidze Z.tsamalaidze V.Amoozegar B.Boghrati M.Ebraimi E.Zareian M.Mohammadi Najafabadi M.Abbrescia G.iaselli G.Pugliese f.Loddo N.De filippis R.Aly D.Ramos W.Elmetenawee S.Leszki i.Margjeka D.Paesani L.Benussi S.Bianco D.Piccolo S.Meola S.Buontempo f.Carnevali L.Lista P.Paolucci f.fienga A.Braghieri P.Salvini P.Montagna C.Riccardi P.Vitulo E.Asilar J.Choi t.J.Kim S.Y.Choi B.Hong K.S.Lee H.Y.Oh J.Goh i.Yu C.Uribe Estrada i.Pedraza H.Castilla-Valdez R.L.fernandez A.Sanchez-Hernandez E.Vazquez M.Ramirez-Garcia N.Zaganidis A.Radi H.Hoorani S.Muhammad A.Ahmad i.Asghar M.A.Shah W.A.Khan J.Eysermans i.Crotty on behalf of the CMS Muon Group Department of Physics and Astronomy Ghent UniversityProeftuinstraat 869000 GhentBelgium UniversitéLibre de Bruxelles Avenue Franklin Roosevelt50-1050 BruxellesBelgium Centro Brasileiro Pesquisas fisicas R.Dr.Xavier Sigaud150UrcaRio de JaneiroRio de Janeiro 22290-180Brazil Department de fisica Nuclear e Altas Energias Instituto de FisicaUniversidade do Estado do Rio de JaneiroRua Sao Francisco Xavier524Rio de JaneiroRio de Janeiro 20559-900Brazil Bulgarian Academy of Sciences Institute for Nuclear Researches and Nuclear EnergyTzarigradsko Shaussee Boulevard 721784 SofiaBulgaria faculty of Physics University of Sofia5 James Bourchier Boulevard1164 SofiaBulgaria School of Physics Peking UniversityBeijing 100871China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences B325Main BuildingNo.19(A)Yuquan RoadShijingshan DistrictBeijing 100049China Universidad de Los Andes Carrera 1No.18A-12BogotáColombia Egyptian Network for High Energy Physics Academy of Scientific Research and Technology101 Kasr El-Einy St.CairoEgypt Suez University SuezCairo RoadElsalam CitySuez 43522Egypt Center for High Energy Physics(CHEP-fU) Faculty of ScienceFayoum UniversityEl-Fayoum 63514Egypt Univ Lyon Univ Claude Bernard Lyon 1CNRS/IN2P3IP2I LyonUMR 582269622 VilleurbanneFrance Georgian technical University 77 Kostava Str.0175 TbilisiGeorgia School of Particles and Accelerators Institute for Research in Fundamental Sciences(IPM)P.O.Box 19395-5531 TehranIran School of Engineering Damghan UniversityDamghan ***Iran iNfN Sezione di BariVia Orabona 470126 BariItaly iNfN Laboratori Nazionali di Frascati(LNF)Via Enrico Fermi 4000044 FrascatiItaly iNfN Sezione di NapoliComplesso University Monte S.AngeloVia Cintia80126 NapoliItaly Dipartimento di ingegneria Elettrica e delle tecnologie dell’informazione UniversitàDegli Studi di Napoli Federico II80126 NapoliI

Purpose the Large Hadron Collider(LHC)at European Organization for Nuclear Research is planned to be upgraded to the high luminosity *** the luminosity makes muon triggering reliable and ofﬂine reconstruction very *** enhance the redundancy of the Compact Muon Solenoid(CMS)Muon system and resolve the ambiguity of track reconstruction in the forward region,an improved Resistive Plate Chamber(iRPC)with excellent time resolution will be installed in the Phase-2 CMS *** iRPC will be equipped with front-End Electronics(fEE),which can perform high-precision time measurements of signals from both ends of the *** Back-End Electronics(BEE)need to be researched and developed to provide sophisticated functionalities such as interacting with fEE with shared links for fast,slow control(SC)and data,in addition to trigger primitives(tPs)generation and data acquisition(DAQ).Method the BEE prototype uses a homemade hardware board compatible with the MtCA standard,the back-end board(BEB).BEE interacts with fEE via a bidirectional 4.8 Gbps optical paired-link that integrates clock,data,and control *** clock and fast/slow control commands are distributed from BEB to the fEE via the *** uplink is used for BEB to receive the time information of the iRPC’sﬁred strips and the responses to the fast/slow control *** have a pipelined detector data for clusterﬁnding operation,recover(DeMux)the time relationship of which is changed due to the transmission protocol for the continuous incoming MUXed data from *** at each bunch crossing(BX),clusteringﬁred strips that satisfy time and spatial constraints to generate *** incoming raw MUXed detector data and tPs in a time window and latency based on the trigger signal are read out to the DAQ *** Ethernet(GbE)of SitCP and commercial 10-GbE are used as link standards for SC and DAQ,respectively,for the BEB to interact with the *** the joint test results of

关键词： CMS iRPC BEE tP DAQ SC

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Enhanced Photocatalytic Activity of tiO2 Nanofibers and their flexible Composite films： Decomposition of Organic Dyes and Efficient H2 Generation from Ethanol-Water Mixtures

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Nano Research 2011年第4期4卷 360-369页

作者： Ming-Chung Wu Andras Sapi Anna avila Maria Szabo Jussi Hiltunen Mika Huuhtanen Geza toth Akos Kukovecz Zoltan Konya Riitta Keiski Wei-fang Su Heli Jantunen Krisztian Kordas Department of Electrical and information Engineering University of Oulu P.O. Box 4500 FI-90014 University of Oulu Finland Department of Applied and Environmental Chemistry University of Szeged 6720 Szeged Rerrich Bela ter 1 Hungary Department of Process and Environmental Engineering P.O. Box 4300 F1-90014 University of Oulu Finland Department of Materials Science and Engineering National Taiwan University Taipei 106-17 Taiwan China

与磅和 Pd nanoparticles 装饰的 tiO2 nanofibers 在各种各样的 photocatalytic 过程被综合了并且学习。在水里的器官的染料的分解的优秀 photocatalytic 行为，灵活独立纤维素 / 催化剂的表面上的器官的污点的降级合成电影并且在从乙... 详细信息

与磅和 Pd nanoparticles 装饰的 tiO2 nanofibers 在各种各样的 photocatalytic 过程被综合了并且学习。在水里的器官的染料的分解的优秀 photocatalytic 行为，灵活独立纤维素 / 催化剂的表面上的器官的污点的降级合成电影并且在从乙醇用的氢的产生推迟了并且使不能调动催化剂被表明。基于 nanofiber 的 tiO2 材料的表演是在某情况 outperformstheir 的竞争 withand 常规基于 nanoparticle 的对应物。在所有情况中，装饰 Pd 的 tiO2 nanoparticles 和 nanofibers 证明了比他们的基于磅的对应物更有效，它能在在 tiO2 和金属 nanoparticles 之间的接触根据缩放 nano 的 Schottky 接口的形成被解释。形成纤维素 / 催化剂 composites 的可行性提供在大区域的涂层和独立电影利用光催化剂材料的一个新奇方法。

关键词： tiO2纳米纳米纤维有机染料复合薄膜光催化活性二氧化钛纳米粒子乙醇分解

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A PROSPECtiVE RANDOMiZED COMPAR-AtiVE StUDY BEtWEEN ENDOSCOPiC CYCLOPHOtOCOAGULAtiON AND tHE AHMED DRAiNAGE iMPLANt iN RE-fRACtORY GLAUCOMA

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国际眼科杂志 2003年第1期3卷 85-86页

作者： f.E.Lima L.Magacho D.M.Carvalho M.P.avila R.Susanna Jr. federal Uni-versity of Goias University of Sao PauloFederal Uni-versity of Goias University of Campinas BrazilFederal Uni- versity of GoiasFederal Uni- versity of GoiasUniversity of Sao Paulo

Purpose: to compare endoscopic cyclophotocoagulation (ECP) and Ahmed drainage implant in the treatment of refractory glaucoma. Methods: 68 eyes with refractory glaucoma were randomized prospectively to either ECP or Ahmed tube shunt implantation, always performed by a single surgeon. Eyes that were included were pseudophakic with a history of at least one tra-beculectomy with an antimetabolite, and a visual acuity

关键词：难治性青光眼内镜睫状体光凝固艾哈默德引流植入物随机比较研究

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Obtaining the Minimum Lethal Dose against <i>fasciola hepatica in Vitro</i>Using Plant Extract Hexanes with fasciolicide Activity and toxicity Evaluation on CD1 Male Mice

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American Journal of Plant Sciences 2012年第7期3卷 899-903页

作者： Stephanie ibarra-Moreno froylan ibarra-Velarde Jose Guillermo avila-Acevedo Depto. De Parasitología. facultad de Medicina Veterinaria. Y Zootecnia. UNAM. Ciudad Universitaria 04510 México D.F. México Lab. De fitoquímica. UBiPRO. facultad de Estudios Superiores iztacala. UNAM. Avenida de los Barrios S/N tlalnepantla de Baz Edo. De México.

fascioliasis is a parasitic disease of worldwide distribution affecting mainly cattle and sheep. its importance lies in the economic losses it produces in the livestock industry. its control is carried out by using a chemical fasciolicide showing resistance problems and environmental contamination. Looking for an alternative control for this disease the present study was aimed at determining the hexane anti-fasciola hepatica in the in vitro effect of some plant extracts and the minimum lethal dose of the mentioned extracts. All selected plants were tested in vitro at concentrations of 500, 250, 125 and 50 mg/L):Achilleamillefolium (plumajillo), Artemisiaabsinthium (wormwood), Artemisia mexicana (estafiate), Castelatortuousa (chaparroamargo), Chenopodiumgraveolens (epazote de zorrillo), Gymnospermaglutinosum (popote) Justicia spicigera (muicle), Limpia critridora (cedron), Lippiagraveolens (oregano), Menthapiperita (Mint), Populus alba (alamo) and thymusvulgaris (thyme). Subsequently proceeded to perform a toxicity study with these fractions in CD1 male mice 10-13 weeks of age, forming groups of 3-5 animals they were administered a single oral dose being (5 mg/kg, 50 mg/kg, 500 mg/kg, 2500 mg/kg and 5000 mg/kg) and were kept under observation 20 days, later were sacrificed and a kidney and liver histology was performed, finding the safety of the extracts. to perform the toxicity study with these fractions, groups of five CD1 male-mice were formed, they were treated with oral doses of 5, 50, 500, 2500 and 5000 mg/kg, administered with a cannule. All mice were kept under observation for 20 days. finally they were sacrificed to perform histology of the kidney and liver in search of possible side effects. Results show that none of the extracts exhibited that fasciolocide activity for mice CD1 even at the highest dose thereforefinding the safety of the extracts.

关键词： fasciola hepatica Plant Extracts in Vitro Minimum Lethal Dose toxicity

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