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基于TOA的中心车辆定位系统的算法研究

通信技术 2001年第5期34卷 23-25页

作者：李俊杰王世练路军张尔扬国防科技大学电子科学与工程学院长沙410073

分析了基于TOA无线电测距的车辆定位系统,主要研究了扩展Kalman滤波算法在其中的应用以及影响定位精度的因素。仿真结果表明,测距误差为20m,定位误差(圆概率误差)可达到15m左右。

关键词： Kalman滤波算法车辆定位系统交通管理

虹膜色素上皮转位治疗渗出性年龄相关性黄斑变性的远期疗效

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世界核心医学期刊文摘（眼科学分册） 2005年第2期1卷 25-26页

作者： Lappas A. foerster A.m.H. Weinberger A.W.A. 陈立军 department of O phthalm.logy University of Aachen Pauwelsstrasse 30 52057 Aachen Germany

Purpose: To report the practicability and efficacy of autologous iris pigment epithelium (IPE) translocation in exudative age-related macular degeneration (A RmD) over 1 year. methods: The consecutive interventional case series included 5 6 patients with exudative ARmD. During vitrectomy the submacular neovascular mem brane (CNV) was removed and IPE cells, harvested from a peripheral iridectomy, w ere injected into the submacular space. Included were patients with subfoveal oc cult CNV (11 eyes), classic CNV (10 eyes), mixed CNV (17 eyes), CNV with a pigme nt epithelial detachment (13 eyes) or CNV with a hemorrhage (5 eyes). Outcome me asures were visual acuity, foveal fixation, size of CNV and rate of recurrence b ased on fluorescence angiographic imaging. Results: All patients underwent succe ssful surgical removal of the CNV with consecutive subretinal IPE injection. Vis ual acuity was better than 20/100 in 19 patients preoperatively and in 18 patien ts postoperatively. A visual acuity of 20/100 or less was found in 37 patients p reoperatively and in 38 patients postoperatively. mean preoperative visual acuit y (1.0±0.3 logmAR units) did not change significantly after 1 year (1.0±0.3 lo gmAR units). Ten eyes (18%) developed a recurrence. fixation within the surgica lly denuded area could be demonstrated in 25 eyes (45%). Conclusions: Autologou s IPE translocation for ARmD over one year can preserve foveal function on a low level, but cannot improve visual acuity. IPE translocation is technically feasi ble with a low rate of complications. Continued research seems justified to impr ove functional outcome.

关键词：色素上皮渗出性远期疗效黄斑中心凹玻璃体切割术脉络膜新生血管复发率荧光造影视功能隐匿型

High prevalence of bla_(CTX-m) in Enterobactcriaceac isolates from the Kingdom of Bahrain

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Asian Pacific Journal of Tropical medicine 2011年第12期4卷 937-940页

作者： Khalid m Bindayna mariam murtadha department of microbiology Immunology & Infectious DiseasesCollege of Medicine and Medical SciencesArabian Gulf UniversityKingdom of Bahrain Salmaniya medical Center Ministry of HealthKingdom of Bahrain

Objective:To determine the molecular epidemiology of extended-spectrumβ-lactamase （ESRL） by testing a cohort of clinical ESBL-producing bacterial isolates that were isolated in the Kingdom of ***:ESBL producing Enterabacleriaceae isolates（based on phenotypie tests） were collected from microbiology Laboratory ot the Salmaniya medical Complex,Bahrain between January-June *** susceptibility to a panel of antibiotics was performed and blaCTX-m genes were detected by multiplex ***:A total of 230 isolates（Escherichia coli.n=180:Klebsiella pneumoniae,n=50） were studied.98%were CTX-m *** Escherichia coli isolates.65（36.1%） harbored CTXm+Tf.m combination and 68（37.8%） had CTX-m *** contrast,for Klebsiella pneumoniae isolates only 5（10.0%） harbored the CTX-m combination,and none had CTX-m *** blaCTX-m gene was found predominantly in urine isolates（n=145/230;63.0%）.Sensitivity to imipenem and nitrofurantoin was 100%and 60%.***-m carriage was associated with the resistance lo fluoroquinolones, trimethoprim-sulfamethoxazole and ***:Our study documentes high prevalence of CTX-m ESBL type among Escherichia call and Klebsiella from the Kingdom of *** apparent dissemination of CTX-m producers could represent a substantial barrier in the treatment of community-acquired *** use of extended-Spectrum cephalosporins. quinolones,and aminoglycosides is compromised,leaving carbapenems as the therapeutic option for severe infections caused by ESBL producers.

关键词： ESBL CTX-m Bahrain Escherichia coli Klebsiella pneumoniae

Host factors Alter Effects of Angiopoietin-Like Protein 8 on Glucose Homeostasis in Diabetic mice

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Journal of Diabetes mellitus 2016年第4期6卷 277-290页

作者： Sichen Liu Emily m. Smith Timothy H. King Lindsey Glenn michelle Trevino So Hyun Park Yui machida Ciriaco Villaflor Wojciech Grzesik margaret A. morris Yumi Imai Jerry L. Nadler Eastern Virginia medical School Department of Internal Medicine Strelitz Diabetes Center Norfolk VA USA department of Internal medicine Fraternal Order of Eagles Diabetes Research Center The University of Iowa Carver College of Medicine Iowa City IA USA

Recovery of functional beta cell mass offers a biological cure for type 1 diabetes. However, beta cell mass is difficult to regain once lost since the proliferation rate of beta cells after youth is very low. Angiopoietin like-protein 8 (ANGPTL8), a peptide that has a role in the regulation of lipoprotein lipase activity, was reported to increase beta cell proliferation in mice in 2013. Subsequent studies of human ANGPTL8 for short term (3 to 8 days) in non-diabetic mice showed little or no increase in beta cell proliferation. Here, we examined the effect of ANGPTL8 on glucose homeostasis in models that have not been examined previously. We expressed mouse ANGPTL8 using adenovirus in 2 mouse models of diabetes (streptozotocin and Non-Obese Diabetic (NOD) mice) over 2 weeks. Also, we tested ANGPTL8 in NOD mice deficient in leukocyte 12-lipoxygenase (12lo), an enzyme that contributes to insulitis and loss of beta cell function in NOD, in an effort to determine whether 12lo deficiency alters the response to ANGPTL8. Adenovirus-mediated expression of ANGPTL8 lowered blood glucose levels in streptozotocin treated mice without an increase in beta cell proliferation or serum insulin concentration. While ANGPTL8 did not reverse hyperglycemia in overtly hyperglycemic NOD mice or alter glucose homeostasis of non-diabetic NOD mice, ANGPTL8 reduced blood glucose levels in 12loKO NOD mice. However, the lower glucose levels in 12loKO NOD were not associated with higher serum insulin levels or beta cell proliferation. In summary, while mouse ANGPTL8 does not increase beta cell proliferation in NOD mice or streptozotocin treated mice in agreement with studies in non-diabetic mice, it lowers blood glucose levels in multiple low-dose streptozotocin induced diabetes and 12lo deficiency indicating that host factors influence the impact of ANGPTL8 on glucose homeostasis.

关键词： Angiopoietin-Like Protein 8 Type 1 Diabetes NOD 12-Lipoxygenase Beta Cells Glucose Homeostasis

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氯胺酮相关性膀胱炎的诊断与治疗

中外医疗 2017年第26期36卷 7-9页

作者：卢穗琳戚德峰刘冠炤单炽昌曾国华广州医科大学第一附属医院微创外科中心泌尿外科/广东省泌尿外科重点实验室/广州市泌尿外科研究室广东广州510230

目的探讨氯胺酮(K粉)所引发的以下尿路症状为主要表现的膀胱炎的诊断与治疗。方法方便选取2008年11月—2016年4月因吸食"K粉"导致氯胺酮相关性膀胱炎的患者40例,首先戒断氯胺酮,服用α受体阻滞剂和m受体阻滞剂对症治疗,同时保护肝肾功能... 详细信息

目的探讨氯胺酮(K粉)所引发的以下尿路症状为主要表现的膀胱炎的诊断与治疗。方法方便选取2008年11月—2016年4月因吸食"K粉"导致氯胺酮相关性膀胱炎的患者40例,首先戒断氯胺酮,服用α受体阻滞剂和m受体阻滞剂对症治疗,同时保护肝肾功能,根据膀胱刺激症状和膀胱挛缩的程度采用透明质酸钠膀胱灌注,和(或)麻醉状态下以生理盐水作为灌注液,进行水压扩张膀胱术;灌注前应常规行膀胱黏膜活检;症状严重者可行回肠膀胱扩大术治疗。结果 40例患者经对症治疗后,下尿路刺激症状缓解,其中血尿消失最快最明显,但尿频尿急缓解较慢。随访1年,只有2例患者由于不能完全杜绝K粉的滥用,出现症状反复。结论氯胺酮相关性膀胱炎可能是一种以下尿路刺激症状为主要表现的膀胱功能损害,其病理结构与间质性膀胱炎相类似,运用上述治疗原则处理,治疗效果满意,值得进一步应用和推广。

关键词：氯胺酮药物滥用尿路炎性损害诊断与治疗

1.5μm波长光通信用高灵敏度高—低(Hi-lo)锗雪崩光电二极管

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半导体光电 1985年第2期 63-65页

作者： m.Niwa Y.Tashiro K.minemura H.Iwasaki 程泰平

研制出用于1.55μm波长光通信系统的高灵敏度,小探测面积的Hi-lo锗雪崩光电二极管。这种器件具有Hi-lo（p;nn;）杂质分布。其光敏区直径是30μm,这有利于单模光纤使用。在传输速率为450mb/S、λ=1.55μm、误码率等于10;、归零制系统中... 详细信息

研制出用于1.55μm波长光通信系统的高灵敏度,小探测面积的Hi-lo锗雪崩光电二极管。这种器件具有Hi-lo（p;nn;）杂质分布。其光敏区直径是30μm,这有利于单模光纤使用。在传输速率为450mb/S、λ=1.55μm、误码率等于10;、归零制系统中得到最小平均可接收信号电平是-40.5dBm。这个值比80μm直径同样结构锗雪崩光电二极管的优0.7dB。

关键词：光通信系统结电容光波通信系统高灵敏度 Hi-lo 波长暗电流保护环耗尽层杂质分布误码率出错率

术前肠内强化营养在食管癌手术治疗中的应用研究

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潍坊医学院学报 2010年第6期32卷 469-471页

作者：杨晶杨兆辉陈德河王永刚石全世枣庄矿业集团枣庄医院胸外科山东枣庄277100 青岛经济开发区第一人民医院呼吸内科

目的观察术前肠内强化营养对食管癌患者手术治疗的影响。方法将2006年1月。2009年lo月胸段食管癌患者120例随机分为研究组和对照组，每组60例。两组均维持入院前饮食质量，研究组于术前5d开始经口肠内营养乳剂“瑞高”500m1强化营养治... 详细信息

目的观察术前肠内强化营养对食管癌患者手术治疗的影响。方法将2006年1月。2009年lo月胸段食管癌患者120例随机分为研究组和对照组，每组60例。两组均维持入院前饮食质量，研究组于术前5d开始经口肠内营养乳剂“瑞高”500m1强化营养治疗。术后均行同质量肠外营养支持和早期肠内营养支持。观察术前体重变化，术前5d、术前1d、术后第2天、术后第8天检测外周静脉血血红蛋白、血清白蛋白、淋巴细胞计数。记录术中静脉复合全麻实施前后中心静脉压、术中静脉补液量，记录术后胸腔引流量、引流时间，肠蠕动恢复时间，术后肠内营养不适发生率。结果术后肠内强化营养组血清白蛋白、术后第8天淋巴细胞计数高于对照组；全麻前后中心静脉压下降、术中补液量、术后胸腔引流量、闭式引流时间、肠蠕动恢复时间、术后早期肠内营养不适发生率均低于对照组，两纽间差异有显著性（P〈0．05）。术前所测体重、血清白蛋白，术前及术后第2天所测淋巴细胞计数及术前术后所测血红蛋白，两组间差异无显著性（P〉0．05）。结论术前短期肠内强化营养治疗可以增加手术的安全性，有利手术恢复，减少并发症发生风险，对术后早期肠内营养的实施有辅助作用，对顺利完成食管癌围手术期治疗有显著效果。

关键词：术前强化肠内营养食管癌

女性生殖道原始神经外胚层肿瘤:19例形态学、免疫组化和分子遗传学分析

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临床与实验病理学杂志 2017年第9期33卷 1062-1062页

作者： Chiang S Snuderl m Kojiro-Sanada S 康锶鹏余英豪不详解放军第180医院病理科泉州362000 解放军福州总医院病理科福州350025

女性生殖道原始神经外胚层肿瘤（PNET）临床罕见，其合适的分类尚未建立。作者报道19例妇科PNET的临床、组织学及免疫组化特征及EWSR1基因重排状态，其中卵巢lo例，子宫8例和会阴部1例。年龄12—68岁，发生于卵巢和子宫PNET平均年龄分别... 详细信息

女性生殖道原始神经外胚层肿瘤（PNET）临床罕见，其合适的分类尚未建立。作者报道19例妇科PNET的临床、组织学及免疫组化特征及EWSR1基因重排状态，其中卵巢lo例，子宫8例和会阴部1例。年龄12—68岁，发生于卵巢和子宫PNET平均年龄分别为20岁和51岁。

关键词：原始神经外胚层肿瘤女性生殖道免疫组化分子遗传学分析形态学 PNET 平均年龄基因重排

THE LAND UTILIZATION Of THE lo-LUNG RIVER BASIN,CHENG-KUNG DISTRICT,YUNNAN

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地理学报 1944年 71-71页

作者： C.m.BAO C.C.CHANG South-Western Associatcd University

(An abstract) Cheng-Kung District lies some 20 km. south of Kunming, on the Yunnan Plateau, at an elevation of about 2,000 metres, and can be reached by both railway and highway. A detailed land utilization survey was... 详细信息

关键词： THE LAND UTILIZATION Of THE lo-LUNG RIVER BASIN,CHENG-KUNG DISTRICT,YUNNAN