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真空炉渗碳

热处理技术与装备 1982年第3期 37-39页

作者： C.H.LUITEN f.LIMQUE f.bless 王宏印一机部郑州机械研究所

在真空炉内进行热处理有许多优点,这已为人们所熟知。除了中性处理外,由于技术的发展,真空炉的用途更加广泛。向真空炉内注入碳氢化合物,比如甲烷或丙烷,便可进行渗碳。为了防止渗碳气体在炉内出观紊流,可以添加纯氮,增加炉压,以便采用... 详细信息

在真空炉内进行热处理有许多优点,这已为人们所熟知。除了中性处理外,由于技术的发展,真空炉的用途更加广泛。向真空炉内注入碳氢化合物,比如甲烷或丙烷,便可进行渗碳。为了防止渗碳气体在炉内出观紊流,可以添加纯氮,增加炉压,以便采用机械手段使炉气更好流通。真空渗炉温度一般为900～1050℃,若

关键词：渗碳甲烷丙烷碳氢化合物含碳量炉气表面硬化沼气烷烃电炉真空炉渗碳温度

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高压气淬在真空热处理炉中的应用

热处理技术与装备 1988年第2期 41-44页

作者： f.bless J.W.Bouwmen 王宝霞喻子建东北工学院东北工学院

七十年代中期,气体的压力在气淬过程中对热传输的显著作用已经得到人们的公认。最初的实践应用只把冷却气体的压力从1巴增加到2巴。后来进一步把气体压力增加到5巴,但只有采用一种新式的气体循环系统与单室真空炉的研制相结合的情况下... 详细信息

七十年代中期,气体的压力在气淬过程中对热传输的显著作用已经得到人们的公认。最初的实践应用只把冷却气体的压力从1巴增加到2巴。后来进一步把气体压力增加到5巴,但只有采用一种新式的气体循环系统与单室真空炉的研制相结合的情况下才能实现。这种炉叫VTTC炉,其冷却气体是以很高的速度从上向下垂直地流过工件的。

关键词：高压气淬油淬单室真空热处理炉真空炉电炉刀具

Merging bound states in the continuum in an open acoustic resonator

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 124-131页

作者： Lujun Huang Bin Jia Artem S.Pilipchuk Sibo Huang Chen Shen Almas f.Sadreev Yong Li Andrey E.Miroshnichenko School of Physics and Electronic Sciences East China Normal University Institute of Acoustics Tongji University L.V.Kirensky Institute of Physics Department of Mechanical Engineering Rowan University School of Engineering and Technology University of New South Wales at Canberra

Bound states in the continuum （BICs） are perfectly localized resonances despite embedding in the continuum ***,an isolated BIC is very sensitive to the structure ***,we report merging acoustic BICs in a single open resonator,robust against the structure *** find that both symmetry-protected BIC and friedrich-Wintgen BIC are sustained in a single coupled waveguide-resonator *** varying the height and length of the resonator,these two BICs move toward each other and merge into a single one at a critical *** to an individual BIC,the merged BIC is robust against fabrication error because its Q-factor is proportional to ΔL-4,whereΔL embodies the structure *** essence of this extraordinary phenomenon is perfectly explained by the two-and three-level approximations of the effective nonHermitian ***,we present direct experimental demonstrations of the moving and merging of BICs in a coupled 3D waveguide-resonator,which are evidenced by the vanishing of the linewidth of fano resonance in the transmission *** results may find exciting applications in designing high-quality acoustic sources,sensors and filters.

关键词： acoustic resonances bound state in the continuum high-Q resonances

Stock Market Index Prediction Using Machine Learning and Deep Learning Techniques

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Intelligent Automation & Soft Computing 2023年第8期37卷 1325-1344页

作者： Abdus Saboor Arif Hussain bless Lord Y。Agbley Amin ul Haq Jian Ping Li Rajesh Kumar Yangtze Delta Region Institute(Huzhou) University of Electronic Science and Technology of ChinaHuzhou313001China Abdul Wali Khan University Mardan Mardan23200Pakistan School of Computer Science and Engineering University of Electronic Science and Technology of ChinaChengdu611731China Brain Institute Peshawar Peshawar25130Pakistan

Stock market forecasting has drawn interest from both economists and computer scientists as a classic yet difficult *** the objective of constructing an effective prediction model,both linear and machine learning tools have been investigated for the past couple of *** recent years,recurrent neural networks(RNNs)have been observed to perform well on tasks involving sequence-based data in many research *** this motivation,we investigated the performance of long-short term memory(LSTM)and gated recurrent units(GRU)and their combination with the attention mechanism;LSTM+Attention,GRU+Attention,and LSTM+GRU+*** methods were evaluated with stock data from three different stock indices:the KSE 100 index,the DSE 30 index,and the BSE *** results were compared to other machine learning models such as support vector regression,random forest,and k-nearest *** best results for the three datasets were obtained by the RNN-based models combined with the attention *** performances of the RNN and attention-based models are higher and would be more effective for applications in the business industry.

关键词： Machine learning deep learning stock market prediction data analysis

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也许，未来

Reflecting on tuberculosis case notification and treatment outcomes in the Volta region of Ghana:a retrospective pool analysis of a multicentre cohort from 2013 to 2017

作者： bless绘画

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Global Health Research and Policy 2019年第1期4卷 1-13页

作者： Eric Osei Samuel Oppong Daniel Adanfo bless Ativor Doepe Andrews Owusu Augustine Goma Kupour Joyce Der Department of Population and Behavioural Sciences School of Public HealthUniversity of Health and Allied SciencesHoGhana Department of Epidemiology School of Public HealthUniversity of Health and Allied SciencesHoGhana

Background:Tuberculosis(TB)remains a petrified condition with a huge economic and health impact on families and health systems in *** of TB programme performance indicators can provide reliable data for direct measurement of TB incidence and *** study reflects on the trends of TB case notification and treatment outcomes and makes comparison among 10 districts of the Volta region of ***:This was a retrospective analysis of surveillance data of a cohort of TB cases from 2013 to *** of case notification and treatment outcomes were examined and *** regression was used to determine the independent relationship between patients and disease characteristics and unsuccessful treatment *** ratios,95%confidence intervals and p-values were ***:A gradual declining trend of case notification of all forms of TB was noticed,with an overall case notification rate(CNR)of 65 cases per 100,000 population during the period.A wide variation of case notification of TB was observed among the districts,ranging from 32 to 124 cases per 100,000 ***,treatment success rate decreased slightly from 83.1%during the first year to 80.2%in 2017,with an overall treatment success rate of 82.5%(95%CI:81.3-83.8%).Treatment failure,death,and lost to follow up rates were 0.8%(range 0.5-1.2%),13.5%(range 12.4-14.7%),and 3.1%(range 2.6-3.8%)*** treatment success rate among districts ranged from 70.5%in South Tongu to 90.8%in Krachi West *** after treatment interruption(Adjusted odds ratio[AOR]:3.62;95%CI:1.66-7.91;Pfection(AOR:1.94;95%CI:1.57-2.40;Pfive years,TB case notification and successful treatment outcomes did not significantly *** district variations in CNR was *** overall treatment success rate observed in this study is below the target of>90%set by the World Health Organiz

关键词： Tuberculosis Case notification Treatment outcomes Volta region Ghana

Hsa-miR-214-3p inhibits breast cancer cell growth and improves the tumor immune microenvironment by downregulating B7H3

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Oncology research 2025年第1期33卷 103-121页

作者： Yan Lu Kang Wang Yuanhong Peng Meng Chen Lin Zhong Luji Huang f U Cheng Xindan Sheng Xin Yang Manzhao Ouyang George A Calin Zhiwei He China-America Cancer Research Institute Guangdong Medical University Dongguan 523808 China. GCP Center Shunde Hospital Southern Medical University (The First People's Hospital of Shunde Foshan) Shunde 528300 China. Department of Gastrointestinal Surgery Shunde Hospital Southern Medical University (The First People's Hospital of Shunde Foshan) Shunde 528300 China. The Second School of Clinical Medicine Southern Medical University Guangzhou 510080 China. Department of Translational Molecular Pathology The University of Texas MD Anderson Cancer Center Houston TX 77030 USA. Department of Oncology Shunde Hospital Southern Medical University (The First People's Hospital of Shunde Foshan) Shunde 528300 China.

Background:Immune checkpoint inhibitors play an important role in the treatment of solid tumors, but the currently used immune checkpoint inhibitors targeting programmed cell death-1 (PD-1), programmed cell death ligand-1 (PD-L1), and cytotoxic T-lymphocyte antigen-4 (CTLA-4) show limited clinical efficacy in many breast cancers. B7H3 has been widely reported as an immunosuppressive molecule, but its immunological function in breast cancer patients remains unclear.Methods:We analyzed the expression of B7H3 in breast cancer samples using data from the Cancer Genome Atlas Program (TCGA) and the Gene Expression Omnibus (GEO) databases. MicroRNAs were selected using the TarBase, miRTarBase, and miRBase databases. The regulatory role of the microRNA hsa-miR-214-3p on B7H3 was investigated through dual-luciferase reporter assays, which identified the specific action sites of interaction. The expression levels of B7H3 and hsa-miR-214-3p in human breast cancer tissues and adjacent normal tissues were quantified using Western blotting and quantitative PCR (qPCR). experiments were performed to observe the effects of modulating the expression of B7H3 or hsa-miR-214-3p on breast cancer cell proliferation and apoptosis. Additionally, the regulatory impact of hsa-miR-214-3p on B7H3 was examined. Enzyme-linked immunosorbent assays (ELISA) and flow cytometry were employed to assess the effects of co-cultured breast cancer cells and normal human peripheral blood mononuclear cells (PBMCs) on immune cells and associated cytokines.Results:In breast cancer tissues, the expression level of B7H3 is inversely correlated with that of hsa-miR-214-3p, as well as with the regulatory effects on breast cancercell behavior. Hsa-miR-214-3p was found to inhibit breast cancer cell growth by downregulating B7H3. Importantly, our research identified, for the first time, two binding sites for hsa-miR-214-3p on the 3' UTR of B7H3, both of which exert similar effects independently. Co-culture experime

关键词： B7H3 Breast cancer Hsa-miR-214-3p Immunotherapy

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高压气淬在真空热处理上的应用

电炉技术 1989年第3期 27-34页

作者： bless,f 沈宏瑛

Complement-dependent neuroinflammation in spinal cord injury:from pathology to therapeutic implications

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Neural Regeneration Research 2025年第5期20卷 1324-1335页

作者： Hassan Saad Bachar El Baba Ali Tfaily firas Kobeissy Juanmarco Gutierrez Gonzalez Daniel Refai Gerald R.Rodts Christian Mustroph David Gimbel Jonathan Grossberg Daniel L.Barrow Matthew f.Gary Ali M.Alawieh Department of Neurosurgery Emory University School of MedicineAtlantaGAUSA Department of Neurology Yale UniversityNew HavenCTUSA Center for Neurotrauma Multiomics&Biomarkers(CNMB)Morehouse School of MedicineAtlantaGAUSA

Spinal cord injury remains a major cause of disability in young adults,and beyond acute decompression and rehabilitation,there are no pharmacological treatments to limit the progression of injury and optimize recovery in this *** the thorough investigation of the complement system in triggering and propagating cerebral neuroinflammation,a similar role for complement in spinal neuroinflammation is a focus of ongoing *** this work,we survey the current literature investigating the role of complement in spinal cord injury including the sources of complement proteins,triggers of complement activation,and role of effector functions in the *** study relevant data demonstrating the different triggers of complement activation after spinal cord injury including direct binding to cellular debris,and or activation via antibody binding to damage-associated molecular *** effector functions of complement have been implicated in spinal cord injury,and we critically evaluate recent studies on the dual role of complement anaphylatoxins in spinal cord injury while emphasizing the lack of pathophysiological understanding of the role of opsonins in spinal cord *** this pathophysiological review,we systematically review the different translational approaches used in preclinical models of spinal cord injury and discuss the challenges for future translation into human *** review emphasizes the need for future studies to dissect the roles of different complement pathways in the pathology of spinal cord injury,to evaluate the phases of involvement of opsonins and anaphylatoxins,and to study the role of complement in white matter degeneration and regeneration using translational strategies to supplement genetic models.

关键词： complement neuroinflammation neuroplasticity regeneration spinal cord injury targeted therapy

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