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Diagnostic delay in oral squamous cell carcinoma: the role of cognitive and psychological variables

International Journal of Oral Science 2014年第1期6卷 39-45页

作者： Vera Panzarella Giuseppe Pizzo f.ancesco Calvino Domenico Compilato Giuseppe colella Giuseppina Campisi Department of Surgical Oncological and Oral Sciences University of Palermo Department of Head/Neck Surgery Oral Cavity and Audio/Verbal Communication Second University of Naples

This retrospective study investigated, in two cohorts of subjects living in Southern Italy and awaiting treatment for oral squamous cell carcinoma （OSCC）, the variables related to diagnostic delay ascribable to the patient, with particular reference to the cognitive and psychological ones. A total of 156 patients with OSCC （mean age： 62 years, M/f： 2.39 ： 1） were recruited at the Universities of Palermo and Naples. Risk factors related to patient delay included： sociodemographic, health-related, cognitive and psychological variables. The analysis was conducted by considering two different delay ranges： dichotomous （≤1 month vs. 〉 1 month） and polytomous （〈1 month, 1-3 months, 〉3 months） delay. Data were investigated by univariate and multivariate analyses and a Pvalue≤0.05 was considered statistically significant. for both delay measurements, the most relevant variables were：＇Personal experience of cancer＇（dichotomous delay： P=0.05, odds ratio （0R）=0.33, 95% confidence interval （CI）=0. 11-0.99; polytomous delay： P=0.006, Chi-square= 10.224） and ＇Unawareness＇（dichotomous delay： P〈0.01, 0R=4.96, 95% CI--2.16-11.37; polytomous delay： P=0.087, Chi-square=4.77）. Also ＇Denial＇（P〈0.01, 0R=6.84, 95% CI=2.31-20.24） and ＇Knowledge of cancer＇（P=0.079, Chi-square=8.359） were found to be statistically significant both for dichotomous and for polytomous categorization of delay, respectively. The findings of this study indicated that, in the investigated cohorts, the knowledge about cancer issues is strongly linked to the patient delay. Educational interventions on the Mediterranean population are necessary in order to increase the patient awareness and to emphasize his/her key role in early diagnosis of OSCC.

关键词： cognitive/psychological factors diagnosis oral squamous cell carcinoma patient delay

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比较CT和18f-fDG PET对复发或难治性霍奇金淋巴瘤的纳武单抗疗效的预测价值

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国际医学放射学杂志 2020年第4期 491-492页

作者： f.Z.Mokrane A.Chen L.H.Schwartz f.Morschhauser A.Stamatoullas J.M.S.de colella 向诗语 UMR1015 Institut Gustave Roussy Université Paris Saclay

复发或难治性霍奇金淋巴瘤(RRHL)病人免疫治疗后的CT和氟18(18f)脱氧葡萄糖(fDG)PET/CT表现尚不清楚。目的比较CT与PET/CT对纳武单抗治疗后早期反应

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The INfREP Network: Present Situation and Recent Results

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Open Journal of Earthquake Research 2019年第2期8卷 101-115页

作者： P. f. Biagi R. colella L. Schiavulli A. Ermini M. Boudjada H. Eichelberger K. Schwingenschuh K. Katzis M. E. Contadakis C. Skeberis I. A. Moldovan M. Bezzeghoud Department of Physics University of Bari Bari Italy Department of Industrial Engineering University of Tor Vergata Rome Italy Space Research Institute Austrian Academy of Sciences Graz Austria Department of Computer Science and Engineering European University Cyprus Nicosia Cyprus Department of Surveying & Geodesy University of Thessaloniki Thessaloniki Greece Seismological Department National Institute of Earth’s Physics Bucharest Romania Geophysical Centre of évora and Physics Department ECT University of évora évora Portugal

VLf/Lf (20 - 300 kHz) radio waves propagation is affected by different factors such as meteorological conditions, solar bursts and geomagnetic activity. At the same time, variations of some parameters in the ground, in the atmosphere and in the ionosphere occurring during the preparatory phase of earthquakes can produce disturbances in the propagation of the previous signals along their radio paths: these disturbances are the radio precursors. Since 2009, several VLf/Lf radio receivers have been installed throughout Europe in order to realize a European (VLf/Lf) radio network for studying the VLf/Lf radio precursors of earthquakes, called the INfREP network. In this paper, at first the description of the present situation of the INfREP network is presented, that is: the location of the receivers, the location of the VLf/Lf transmitters whose signal is sampled, the daily download of the data collected by the receivers on the INfREP server and the method of data analysis used in order to individuate possible radio precursors. Then the results obtained on the occasion of recent (2016-2017) seismic activities which occurred in the “sensitive” zone of the INfREP network are presented. The first case examined is the October 30, 2016 earthquake with Mw = 6.5, which occurred in Central Italy, near Norcia small town;this earthquake was preceded by a strong shock (Mw = 5.9) which occurred 4 days before. The second case presented is the strong (Mw = 6.7) offshore earthquake which occurred on July 20, 2017, near the coast of Turkey and Kos island (Greece) and the third case is the August 8, 2017 earthquake with Mw = 5.0, which also occurred near the coast of Turkey and Kos island (Greece). In all the previous cases radio anomalies were revealed in some radio signals collected by the receiver located in Cyprus. The influence of causes different from seismicity as geomagnetic activity and solar burst, meteorological conditions, malfunction of the receiver and/or the transmitters

关键词： Earthquakes VLf/Lf Radio-Waves Precursors

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