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Novel Sustainable Cellulose Acetate Based Biosensor f.r Glucose Detection

Journal of.Renewable m.terials 2024年第2期12卷 369-380页

作者： m.f.Elkady E.m.El-Sayed m.hm.ud Sam. Om.eya A.Koriem.H.Shokry Hassan Chem.cal and Petrochem.cal Engineering Departm.nt Egypt-Japan University of Science and TechnologyNew Borg El-ArabAlexandriaEgypt f.brication Technology Research Departm.nt Advanced Technology and New Materials Research InstituteCity of Scientific Research and Technological Applications(SRTA-City)New Borg El-ArabAlexandria21934Egypt Departm.nt of.Public Works Engineering Faculty of EngineeringMansoura UniversityMansoura35516Egypt Environm.ntal Engineering Departm.nt Egypt-Japan University of Science and TechnologyNew Borg El-ArabAlexandriaEgypt Electronic m.terials Research Departm.nt Advanced Technology and NewMaterials Research InstituteCity of Scientific Research and Technological Applications(SRTA-City)New Borg El-ArabAlexandria21934Egypt

In this study,green zinc oxide(ZnO)/polypyrrole(Ppy)/cellulose acetate(CA)f.lm.has been synthesized via solvent *** f.lm.was used as supporting m.terial f.r glucose oxidase(GOx)to sensitize a glucose *** nanoparticles have been prepared via the green route using olive leaves extract as a ***/Ppy nanocom.osite has been synthesized by a sim.le in-situ chem.cal oxidative polym.rization of.pyrrole(Py)m.nom.r using f.rric chloride(f.Cl3)as an oxidizing *** produced m.terials and the com.osite f.lm. were characterized using X-ray dif.raction analysis(XRD),scanning electron m.croscope(SEm.,f.urier transf.rm.inf.ared(f.IR)and therm.gravim.tric analysis(TGA).Glucose oxidase was successf.lly im.obilized on the surf.ce of.the prepared f.lm.and then ZnO/Ppy/CA/GOx com.osite was sputtered with platinum.electrode f.r the current determ.nation at dif.erent initial concentrations of.*** m.asurem.nts proved the suitability and the high sensitivity of.the constructed biosensor f.r the detection of.glucose levels in dif.erent *** perf.rm.nce of.the prepared biosensor has been assessed by m.asuring and com.aring glucose concentrations up to 800 *** results af.irm.d the reliability of.the developed biosensor towards real sam.les which suggests the wide-scale application of.the proposed biosensor.

关键词： Biosensors com.osite f.lm. glucose polypyrrole green ZnO cellulose acetate

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Evasive attacks against autoencoder-based cyberattack detection system. in power system.

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Energy and AI 2024年第3期17卷 126-135页

作者： Yew m.ng Khaw Am.r Abiri Jahrom. m.ham.adreza f.m.Arani Deepa Kundur Departm.nt of.Electrical and Com.uter Engineering University of TorontoTorontoON M5S 3G4Canada School of.Electronic and Electrical Engineering University of LeedsLeedsLS29JTUnited Kingdom Departm.nt of.Electrical Computer&Biomedical EngineeringToronto Metropolitan University(formerly Ryerson University)TorontoON M5B 2K3Canada

The digital transf.rm.tion process of.power system. towards sm.rt grids is resulting in im.roved reliability, ef.iciency and situational awareness at the expense of.increased cybersecurity vulnerabilities. Given the availability of.large volum.s of.sm.rt grid data, m.chine learning-based m.thods are considered an ef.ective way to im.rove cybersecurity posture. Despite the unquestionable m.rits of.m.chine learning approaches f.r cybersecurity enhancem.nt, they represent a com.onent of.the cyberattack surf.ce that is vulnerable, in particular, to adversarial attacks. In this paper, we exam.ne the robustness of.autoencoder-based cyberattack detection system. in sm.rt grids to adversarial attacks. A novel iterative-based m.thod is f.rst proposed to craf. adversarial attack sam.les. Then, it is dem.nstrated that an attacker with white-box access to the autoencoder-based cyberattack detection system. can successf.lly craf. evasive sam.les using the proposed m.thod. The results indicate that naive initial adversarial seeds cannot be em.loyed to craf. successf.l adversarial attacks shedding insight on the com.lexity of.designing adversarial attacks against autoencoder-based cyberattack detection system. in sm.rt grids.

关键词： Cybersecurity Adversarial attacks Anom.ly detection Iterative-based m.thods Substati on autom.ti on

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RPLP0/TBP are the m.st stable ref.rence genes f.r hum.n dental pulp stem.cells under osteogenic dif.erentiation

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World Journal of.Stem.Cells 2024年第6期16卷 656-669页

作者： Daniel B f.rreira Leticia m.Gasparoni Cristiane f.Bronzeri Katiucia B S Paiva Laboratory of.Extracellular m.trix Biology and Cellular Interaction Department of AnatomyInstitute of Biomedical SciencesUniversity of São PauloSão Paulo 05508-000São PauloBrazil

BACKGROUND Validation of.the ref.rence gene(RG)stability during experim.ntal analyses is essential f.r correct quantitative real-tim. polym.rase chain reaction(RT-qPCR)data ***,in an unreliable way,several studies use genes involved in essential cellular f.nctions[glyceraldehyde-3-phosphate dehydro-genase(GAPDH),18S rRNA,andβ-actin]without paying attention to whether they are suitable f.r such experim.ntal conditions or the reason f.r choosing such ***,such studies use only one gene when m.nim.m.Inf.rm.tion f.r Publication of.Quantitative Real-Tim. PCR Experim.nts guidelines recom.m.nd two or m.re *** im.acts the credibility of.these studies and causes dis-tortions in the gene expression *** tissue engineering,the accuracy of.gene expression drives the best experim.ntal or therapeutical *** cultivated DPSCs under two conditions:Undif.erentiated and osteogenic dif.f.rentiation,both f.r 35 *** evaluated the gene expression of.10 candidates f.r RGs[ribosom.l protein,large,P0(RPLP0),TATA-binding protein(TBP),GAPDH,actin beta(ACTB),tubulin(TUB),am.nolevulinic acid synthase 1(ALAS1),tyro-sine 3-m.nooxygenase/tryptophan 5-m.nooxygenase activation protein,zeta(YWHAZ),eukaryotic translational elongation f.ctor 1 alpha(Ef.a),succinate dehydrogenase com.lex,subunit A,f.avoprotein(SDHA),and beta-2-m.cro-globulin(B2m.]every 7 d(1,7,14,21,28,and 35 d)by *** data were analysed by the f.ur m.in algorithm.,ΔCt m.thod,geNorm.Norm.0}nder,and BestKeeper and ranked by the Ref.inder *** subdivided the sam.les into eight *** All of.the data sets f.om.clonogenic and osteogenic sam.les were analysed using the Ref.inder *** f.nal ranking showed RPLP0/TBP as the two m.st stable RGs and TUB/B2m.as the two least stable *** theΔCt m.thod or Norm.0}nder analysis showed TBP/RPLP0 as the two m.st stable ***,geNorm.analysis showed RPLP0/Ef.αin the f.rst *** algorithm.’two least stab

关键词： Dental pulp stem.cells Ref.rence gene Housekeeping gene Endogenous gene Osteogenic dif.erentiation Ref.inder

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m.delling dynam.c pantograph loads with com.ined num.rical analysis

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Railway Engineering Science 2024年第1期32卷 81-94页

作者： f.f.Jackson R.m.shra J.m.Rebelo J.Santos P.Antunes J.Pom.o H.m.galhaes L.Wills m.Askill School of.Com.uting and Engineering University of HuddersfieldHuddersfieldUK School of.Com.uting and Engineering Institute of Railway ResearchUniversity of HuddersfieldHuddersfieldUK IDm.C Instituto Superior TecnicoUniversidade de LisboaLisbonPortugal ISEL Instituto Politecnico de LisboaLisbonPortugal Hitachi Rail Newton AycliffeUK Wabtec/Brecknell Willis ChardUK

Appropriate interaction between pantograph and catenary is im.erative f.r sm.oth operation of.electric *** heights of.overhead lines to accom.odate level crossings,overbridges,and tunnels pose signif.cant challenges in m.intaining consistent current collection perf.rm.nce as the pantograph aerodynam.c prof.le,and thus aerodynam.c load changes signif.cantly with operational *** research aim. to analyse the global f.ow characteristics and aerodynam.c f.rces acting on individual com.onents of.an HSX pantograph operating in dif.erent conf.gurations and orientations,such that the results can be com.ined with m.ltibody sim.lations to obtain accurate dynam.c insight into contact ***,com.utational f.uid dynam.cs sim.lations are used to investigate the pantograph com.onent loads in a representative setting,such as that of.the recessed cavity on a Class 800 *** an aerodynam.c perspective,this study indicates that the total drag f.rce acting on non-f.xed com.onents of.the pantograph is larger f.r the knuckle-leading orientation rather than the knuckle-trailing,although the dif.erence between the two is f.und to reduce with increasing pantograph *** the aerodynam.c loads acting on individual com.onents with m.ltibody tools allows f.r realistic dynam.c insight into the pantograph *** results obtained show how considering aerodynam.c f.rces enhance the realism.of.the m.dels,leading to behaviour of.the pantograph-catenary contact f.rces closely m.tching that seen in experim.ntal tests.

关键词： Pantograph-catenary interaction Pantograph aerodynam.cs Com.utational f.uid dynam.cs Pantograph loads Current collection perf.rm.nce

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Drought events inf.uence nutrient canopy exchanges and green leaf.partitioning during senescence in a deciduous f.rest

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f.rest Ecosystem. 2024年第1期11卷 110-119页

作者： J.Touche C.Calvaruso P.De Donato m.-P.Turpault INRAE BEFF-54000NancyFrance Um. 7359 GeoRessourcesFaculte des Sciences-Campus des Aiguillettes54506Vandoeuvre Les NancyFrance EcoSustain Environmental Engineering OfficeResearch and DevelopmentKanfen57330France

The increase in the f.equency and intensity of.drought events expected in the com.ng decades in Western Europe m.y disturb f.rest biogeochem.cal cycles and create nutrient def.ciencies in *** possible origin of.nutrient def.ciency is the disturbance of.the partitioning of.the green leaf.pool during the leaf.senescence period between resorption,f.liar leaching and senesced ***,the ef.ects of.drought events on this partitioning and the consequences f.r the m.intenance of.tree nutrition are poorly *** experim.nt in a beech f.rest in m.use(f.ance)was conducted to assess the ef.ect of.drought events on nutrient canopy exchanges and on the partitioning of.the green leaf.pool during the leaf.senescence *** aim.was to identif. potential nutritional consequences of.droughts f.r *** nutrient dynam.cs,including resorption,chem.stry of.green and senesced leaves,f.liar absorption and leaching in m.ture beech stands f.om.2012 to 2019 allowed us to com.are the nutrient exchanges f.r three nondry and three dry years(i.e.,with an intense drought event during the growing season).During dry years,we observed a decrease by alm.st a third of.the potassium.K)partitioning to resorption(*** ef.iciency),thus reducing the K reserve in trees f.r the next growing *** result suggests that with the increased drought f.equency and intensity expected f.r the com.ng decades,there will be a risk of.potassium.def.ciency in trees,as already observed in a rainf.ll exclusion experim.nt on the sam. study *** f.liar leaching and higher parititioning to the senesced leaves f.r K and phosphorus(P)were also *** addition,a slight increase in nitrogen(N)resorption ef.iciency occurred during dry years which is m.re likely to im.rove tree *** calcium.Ca)negative resorption decreased,with no apparent consequence in our study *** results show that nutrient exchanges in the canopy and the partitioning of.the green leaf

关键词： Natural drought Beech f.rest Canopy Resorption f.liar leaching Senesced leaves Nutrition

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Sex dif.erences in the risk of.retinopathy of.prem.turity:a system.tic review,f.equentist and Bayesian m.ta‑analysis,and m.ta‑regression

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World Journal of.Pediatrics 2024年第4期20卷 340-352页

作者： Tam.ra m.Hundscheid Silvia Gulden m.ham.d f.Alm.tairi f.antišek Bartoš Giacom. Cavallaro Eduardo Villam.r Division of.Neonatology Department of PediatricsMosaKids Children’s HospitalMaastricht University Medical Center(MUMC+)School for Oncology and Reproduction(GROW)Maastricht UniversityP.Debyelaan 25.P.O.Box 58006202 AZ MaastrichtThe Netherlands Neonatal Intensive Care Unit Sant’Anna HospitalComoItaly Departm.nt of.Psychology University of Amsterdam1001 NK AmsterdamThe Netherlands Neonatal Intensive Care Unit Fondazione IRCCS Ca’Granda Ospedale Maggiore PoliclinicoMilanItaly

Background Retinopathy of.prem.turity(ROP)is generally considered to be m.re f.equent in m.les than in ***,it is not known whether sex dif.erences in ROP af.ect all degrees of.the condition,are global and have changed as neonatology has *** aim.d to conduct a system.tic review and m.ta-analysis of.studies addressing sex dif.erences in the risk of.developing *** Pubm.d/m.DLINE and Em.ase databases were *** f.equentist,random.ef.ects risk ratio(RR)and 95%conf.dence interval(CI)were *** m.del averaged(Bm.)m.ta-analysis was used to calculate the Bayes f.ctors(Bf.).The Bf.0 is the ratio of.the probability of.the data under the alternative hypothesis(H1)over the probability of.the data under the null hypothesis(H0).Results We included 205 studies(867,252 inf.nts).f.equentist m.ta-analysis showed a positive association between m.le sex and severe ROP(113 studies,RR=1.14,95%CI=1.07–1.22)but no association with any ROP(144 studies,RR=1.00,95%CI=0.96–1.03).Bm. showed extrem. evidence in f.vor of.H1 f.r severe ROP(Bf.0=71,174)and strong evidence in f.vor of.H0 f.r any ROP(Bf.0=0.05).The association between m.le sex and severe ROP rem.ined stable over tim. and was present only in cohorts f.om.countries with a high or high-m.ddle sociodem.graphic *** Our study conf.rm. the presence of.a m.le disadvantage in severe ROP but not in less severe f.rm. of.the *** are variations in the sex dif.erences in ROP,depending on geographical location and sociodem.graphic level of.the countries.

关键词： Oxidative stress Retinopathy of.prem.turity Sex characteristics

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Dysprosium.oxide,alum.na,and graphene oxide reinf.rced polycaprolactone thin f.lm.:Therm.l stability,m.rphology,and cell viability

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Journal of.Rare Earths 2024年第7期42卷 1337-1343,I0005页

作者： m.ham.d Tharwat Elabbasy m.ham.d R.Atteya m.i A.Sam.k m.usa Abdelrahm.n Tahani Alm.hm.ud m.A.El-m.rsy A.A.m.nazea m.f.H.Abd El-Kader Departm.nt of.Public Health College of Public Health and Health InformaticsUniversity of Ha'ilHa'il2440Saudi Arabia f.od Control Departm.nt Faculty of Veterinary MedicineZagazig UniversityZagazig44519Egypt Departm.nt of.Physical Therapy College of Applied Medical SciencesUniversity of Ha'ilHa'ilSaudi Arabia Departm.nt of.Histology and Cell Biology Faculty of MedicineZagazig UniversityZagazig44519Egypt College of.Nursing University of Ha'ilHa'ilSaudi Arabia College of.Science and Hum.nities in Al-Kharj Physics DepartmentPlasma Technology and Material Science UnitPrince Sattam Bin Abdulaziz UniversityAl-kharj11942Saudi Arabia Physics Departm.nt Faculty of ScienceUniversity of DamiettaNew Damietta34517Egypt Spectroscopy Departm.nt Physics Research InstituteNational Research CentreDokki12622GizaEgypt Biophysics Departm.nt Faculty of ScienceCairo UniversityGizaEgypt

Developing a biom.terial f.r wound healing applications is still a ***,dysprosium.oxide(Dy_(2)O_(3)),alum.num.oxide(Al_(2)O_(3)),and graphene oxide(GO)were em.edded in cast f.lm. based on polycaprolactone(PCL)to be exam.ned f.r wound dressing *** techniques were used to characterize the f.bricated f.lm. including X-ray dif.raction(XRD),f.urier transf.rm.inf.ared spectroscopy(f.IR),Ram.n,and scanning electron m.croscopy(SEm.,besides their biological *** therm.gravim.tric analysis(TGA)exhibits high therm.l stability as the scaf.old weight decreases slightly to 98.6%af.er raising the tem.erature f.om.room.tem.erature to 280℃.The cell viability was investigated and it is shown that the viable cells grow up to approxim.tely 93%at 75μg/***,the cell attachm.nt shows excellent behavior as the cells attach on m.st of.the surf.ce of.the m.dif.ed PCL which shows high biocom.atibility.

关键词： Wound healing Polycaprolactone Dy_(2)O_(3) Al_(2)O_(3) Biocom.atible Rare earths

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m.niSCIDOm. a scintillator-based tom.graph f.r volum.tric dose reconstruction of.single laser-driven proton bunches

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High Power Laser Science and Engineering 2024年第2期12卷 41-50页

作者： A.Corvino m.Reim.ld E.Beyreuther f.-E.Brack f.Kroll J.Pawelke J.D.Schilz m.Schneider U.Schram. m.E.P.Um.andt K.Zeil T.Ziegler J.m.tzkes-Ng Helm.oltz-Zentrum.Dresden–Rossendorf DresdenGermany Technische Universität Dresden DresdenGermany OncoRay–National Center f.r Radiation Research in Oncology Faculty of Medicine and University Hospital Carl Gustav CarusTUD Dresden University of TechnologyHelmholtz-Zentrum Dresden–RossendorfDresdenGermany Current af.iliation:Institut Curie UniversitéPSLCNRS UMR3347OrsayFrance Current af.iliation:Universitätsklinikum.f.eiburg FreiburgGermany

Laser plasm. accelerators(LPAs)enable the generation of.intense and short proton bunches on a m.crom.tre scale,thus of.ering new experim.ntal capabilities to research f.elds such as ultra-high dose rate radiobiology or m.terial *** spectrally broadband,laser-accelerated proton bunches allow f.r tailored volum.tric dose deposition in a sam.le via single bunches to excite or probe specif.c sam.le *** rising num.er of.such experim.nts indicates a need f.r diagnostics providing spatially resolved characterization of.dose distributions with volum.s of.approxim.tely 1 cm.(3) f.r single proton bunches to allow f.r f.st online *** we present the scintillator-based m.niSCIDOm.detector f.r online single-bunch tom.graphic reconstruction of.dose distributions in volum.s of.up to approxim.tely 1 cm.(3).The detector achieves a spatial resolution below 500μm.and a sensitivity of.100 *** detector perf.rm.nce is tested at a proton therapy cyclotron and an LPA proton *** experim.nts’prim.ry f.cus is the characterization of.the scintillator’s ionization quenching behaviour.

关键词： beam.m.nitoring detectors laser-driven proton beam. scintillator-based diagnostics ultra-high dose rate

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Optim.zation of.Stealthwatch Network Security System.f.r the Detection and m.tigation of.Distributed Denial of.Service (DDoS) Attack: Application to Sm.rt Grid System

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Com.unications and Network 2024年第3期16卷 108-134页

作者： Em.anuel S. Kolawole Penrose S. Cof.e John H. f.ller Cajetan m. Akujuobi Em.anuel A. Dada Justin f. f.rem.n Pam.la H. Obiom.n Electrical and Com.uter Engineering Departm.nt Prairie View A&M University Prairie View TX USA

The Sm.rt Grid is an enhancem.nt of.the traditional grid system.and em.loys new technologies and sophisticated com.unication techniques f.r electrical power transm.ssion and distribution. The Sm.rt Grid’s com.unication network shares inf.rm.tion about status of.its several integrated IEDs (Intelligent Electronic Devices). However, the IEDs connected throughout the Sm.rt Grid, open opportunities f.r attackers to interf.re with the com.unications and utilities resources or take clients’ private data. This developm.nt has introduced new cyber-security challenges f.r the Sm.rt Grid and is a very concerning issue because of.em.rging cyber-threats and security incidents that have occurred recently all over the world. The purpose of.this research is to detect and m.tigate Distributed Denial of.Service [DDoS] with application to the Electrical Sm.rt Grid System.by deploying an optim.zed Stealthwatch Secure Network analytics tool. In this paper, the DDoS attack in the Sm.rt Grid com.unication networks was m.deled using Stealthwatch tool. The sim.lated network consisted of.Secure Network Analytic tools virtual m.chines (Vm.), electrical Grid network com.unication topology, attackers and Target Vm.. f.nally, the experim.nts and sim.lations were perf.rm.d, and the research results showed that Stealthwatch analytic tool is very ef.ective in detecting and m.tigating DDoS attacks in the Sm.rt Grid System.without causing any blackout or shutdown of.any internal system. as com.ared to other tools such as GNS3, NeSSi2, NISST f.am.work, Om.eT++, INET f.am.work, ReaSE, NS2, NS3, m. Sim.lator, OPNET, PLC & TIA Portal m.nagem.nt Sof.ware which do not have the capability to do so. Also, using Stealthwatch tool to create a security baseline f.r Sm.rt Grid environm.nt, contributes to risk m.tigation and sound security hygiene.

关键词： Sm.rt Grid System Distributed Denial of.Service (DDoS) Attack Intrusion Detection and Prevention System. Detection m.tigation and Stealthwatch

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Developm.nt of.an ultrathin liquid sheet target f.r laser ion acceleration at high repetition rates in the kilohertz range

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High Power Laser Science and Engineering 2024年第3期12卷 134-145页

作者： m.f.le A.P.Kovács T.Gilinger m.Karnok P.Gaál S.f.gul G.m.rowsky K.Osvay National Laser-Initiated Transm.tation Laboratory University of SzegedSzegedHungary Departm.nt of.Experim.ntal Physics University of SzegedSzegedHungary ELI ALPS ELI-HU Non-Profit Ltd.SzegedHungary Departm.nt of.Optics and Quantum.Electronics University of SzegedSzegedHungary Advanced m.crof.uidic System. Gm.H GöttingenGermany

A colliding m.crojet liquid sheet target system.was developed and tested f.r pairs of.round nozzles of.10,11 and 18μm.in *** sheet's position stability was f.und to be better than a f.w *** interaction with 50 m. laser pulses,the 18μm.jet has a resonance am.litude of.16μm.at a repetition rate of.33 Hz,while towards 100 Hz it converges to 10μm.f.r all nozzles.A white-light interf.rom.tric system.was developed to m.asure the liquid sheet thickness in the target cham.er both in air and in vacuum.with a m.asurem.nt range of.182 nm.1μm.and an accuracy of.3%.The overall shape and 3D shape of.the sheet f.llow the Hasson±Peck m.del in *** vacuum.versus air,the sheet gradually loses 10%of.its thickness,so the thinnest sheet achieved was below 200 nm.at a vacuum.level of.10±4m.ar,and rem.ined stable f.r several hours of.operation.

关键词： diagnostics laser ion acceleration nanom.tric liquid sheet targets vacuum.test

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