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COVID-19/Tuberculosis Co-Infection at the Epidemic Treatment Center (ETC) of Saint-Louis (Senegal): About 9 Cases

Advances in Infectious Diseases 2024年第1期14卷 56-66页

作者： Alassane Dièye Moustapha Diedhiou Papa Latyr Junior Diouf mba Bambo Diakhaby Demba Makalou Samba Niang Diatou Dia-Gueye Amadou Diop Dia Ibrahima Louis Martin Dieng Seynabou Lô Ndéye Méry Dia-Badiane Health Sciences Training and Research Unit Gaston Berger University Saint-Louis Senegal Department of Medicine Saint-Louis Regional Hospital Saint-Louis Senegal Infectious and Tropical Diseases Clinic of fann Dakar Senegal

Introduction: COVID-19 is a global public health emergency that can cause acute respiratory distress syndrome. In countries where tuberculosis (TB) is endemic, coinfection of COVID-19 and TB is often encountered, which increases the risk of developing severe forms of COVID-19. Objectives: The aim of this study was to determine the prevalence of COVID-19/TB coinfection at the Epidemic treatment center (ETC) in Saint-Louis (Senegal) and to describe the epidemiological, clinical, paraclinical, and outcome profile of co-infected patients. Patients and Methods: This is a retrospective, cross-sectional, descriptive cohort study based on the records of COVID-19/ TB co-infected patients who were hospitalized at the ETC in Saint-Louis (Senegal) over an 18-month period from March 2020 to September 2021. Results: Out of a total of 454 hospitalizations, we collected records of 9 patients co-infected with COVID-19/TB, resulting in a prevalence of 2%. The study included patients with a median age of 34 years (range: 10-86 years), with a male predominance (7 cases) and a sex ratio of 3.5. The majority of patients (88.9%) had severe forms of COVID-19. Dyspnea and cough were reported in all patients (100%). Pulmonary TB was the most frequent localization, with 9 cases. The diagnosis of COVID-19 was confirmed by nasopharyngeal PCR in all patients (100%). Bacilloscopy was positive in 3 out of 5 cases. One patient tested positive for GeneXpert? MTB/RIf without rifampicin resistance. All patients were prescribed the hydroxychloroquine-azithromycin combination and anti-tuberculosis treatment. Out of the nine patients, four recovered (44.4%) and five died (55.5%). Conclusion: COVID-19/TB coinfection had a low prevalence in our cohort, but was associated with a high mortality due to the frequent occurrence of severe forms of the disease.

关键词： COVID-19 Tuberculosis Saint-Louis Senegal

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Influence of Prenatal Surveillance on Maternal and Perinatal Prognosis: A Prospective Study over 6 Months at the Maternity Ward of the Owendo University Hospital (Gabon)

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Open Journal of Obstetrics and Gynecology 2024年第2期14卷 301-311页

作者： Boniface Sima Ole Sidy Gérard mba Edou Ulysse Minkobam Désire Assoume Ophélie Makoyo Komba Nathalie Ambounda Pamphile Assoumou Jacques Albert Bang Ntamack Sosthène Mayi Tsonga Jean françois Meye Department of Obstetrics and Gynaecology Owendo University Hospital Owendo Gabon Department of Obstetrics and Gynecology Faculty of Medicine of Libreville Libreville Gabon

Introduction: The occurrence of pregnancy in women is a risky situation. Prenatal care is necessary, which is not often the case in our context. Aim: To analyze the influence of antenatal surveillance on maternal and perinatal prognosis. Patients and Method: Preliminary longitudinal and analytical survey at the Owendo University Hospital (OHU) over 6 months. It focused on prenatal surveillance. The study population consisted of parturients who gave birth within 24 hours and we studied sociodemographic characteristics, variables related to antenatal contact, those of delivery as well as maternal and newborn outcomes. Results: 2485 deliveries were recorded and 1300 patients were retained according to the inclusion criteria. No prenatal contact (ANC0) was performed in 93 (7.15%), insufficient (ANCI) in 943 patients (72.5%), and sufficient (ANCS) in 264 patients (20.30%). Patients with low school level were significantly found when the NPC was not performed or insufficient and the same was true for the group of patients who were not employed and those who were single (p f prenatal contact is insufficient in our context. The absence or inadequacy of the latter has a strong negative impact on maternal and perinatal morbidity and mortality.

关键词： ANC Insufficiency Maternal Pathologies Perinatal Death Gabon

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临床试验在JAMA的发表：作者须知

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美国医学会杂志（中文版） 2008年第3期27卷 178-179页

作者： Phil B. fontanarosa, MD, mba Catherine D. DeAngelis, MD, MPH 李呈亿(译)

JAMA杂志的办刊宗旨是：“促进医学科技发展，提高公共健康水平。这一目标的实现涉及重要生物医学研究和临床试验的发表。严格的随机临床试验（randomized clinicaltrials，RCTs）可为临床医生及其他相关专业人员更好地医治患者提供最... 详细信息

JAMA杂志的办刊宗旨是：“促进医学科技发展，提高公共健康水平。这一目标的实现涉及重要生物医学研究和临床试验的发表。严格的随机临床试验（randomized clinicaltrials，RCTs）可为临床医生及其他相关专业人员更好地医治患者提供最高水平的有关治疗干预的科学证据，并最终改善公众的健康水平。为此，JAMA选择优先发表高质量的重要RCTs。

关键词：随机临床试验 JAMA 作者健康水平医学科技办刊宗旨医学研究科学证据

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Profile of Infectious Spondylodiscitis in Rheumatology Consultation at University Teaching Hospital of Kara, Togo

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Open Journal of Rheumatology and Autoimmune Diseases 2021年第4期11卷 160-168页

作者： Prenam Houzou Awaki-Esso Atake Kodjo Kakpovi Viwale E. Koffi-Tessio Komi C. Tagbor Eyram fianyo Sadat Oniankitan Mamadou L. Diallo Pahimi Yibe Erika Djougnwe mba Poyode Lokou Owonayo Oniankitan Moustafa Mijiyawa Department of Rheumatology University Teaching Hospital of Kara Kara Togo Department of Rheumatology Regional Hospital of Kara Tomdè Kara Togo Department of Rheumatology University Teaching Hospital Sylvanus Olympio Lomé Togo Department of Rheumatology District Hospital of Bè Lomé Togo

Objectives: The objective is to determine the frequency and the semiological and evolutionary profiles of infectious spondylodiscitis in hospital practice in Kara. Patients and methods: This was a cross-sectional study of a case series of patients with infectious spondylodiscitis, who were admitted to the rheumatology department of Kara University Hospital in North Togo. Results: Among the 3972 examined patients, 86 (33 males and 53 females) patients (2.16%) had infectious spondylodiscitis. The average age of these patients at the onset of the disease was 47.20 years. The average duration of the disease was 11.41 months. Tuberculosis was suspected in 77 of 86 patients (89.53%). The infectious spondylodiscitis most often affected the lumbar (51.04%) and dorsal (21.87%) segments and was associated with a pulmonary location in 31 patients (36.04%). In addition to underdevelopment and poor hygiene (72 cases), alcoholism (15 cases) and human immunodeficiency virus infection (10 cases) were the main risk factors identified. The progress with the medical treatment was favorable in 65 patients (75.58%) and 16 patients were lost to follow-up. Conclusion:font-family:Verdana;"> The frequency of infectious spondylodiscitis reflects the underdevelopment and poor hygiene levels in Black Africa. Its etiology is most commonly associated with tuberculosis and remain

关键词： Infection Spondylodiscitis Tuberculosis Black Africa

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Infectious Spondylodiscitis in the Elderly in a Rheumatological Setting in Togo

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Open Journal of Rheumatology and Autoimmune Diseases 2022年第1期12卷 1-8页

作者： Kodjo Kakpovi Awaki-Esso Atake Prenam Houzou Issa Diallo Mamadou L. Diallo Viwale E. Koffi-Tessio Komi C. Tagbor Sadat Oniankitan Pahimi Yibe Erika Djougnwe mba Moubarak Tiadjeri Eyram fianyo Owonayo Oniankitan Moustafa Mijiyawa Department of Rheumatology Regional Hospital of Kara Kara Togo Department of Rheumatology University Teaching Hospital of Kara Kara Togo Department of Rheumatology University Teaching Hospital Sylvanus Olympio Lomé Togo Department of Rheumatology District Hospital of Bè Lomé Togo

Infectious spondylodiscitis in the elderly is a diagnostic and therapeutic emergency. They are mainly a functional and sometimes vital prognosis issue, with long-term chronic disabling sequelae and significant social costs. Study aim: To describe the epidemiological, clinical, paraclinical, therapeutic and evolutionary aspects of infectious spondylodiscitis in the elderly in a rheumatological setting in Togo. Patients and methods: This was a multicenter, cross-sectional study conducted on the records of patients aged at least 65 years, suffering from infectious spondylodiscitis and hospitalized in four rheumatology units from their respective opening dates till December 31, 2020. Data collection lasted three months (December 1, 2020 to february 29, 2021). The diagnosis of infectious spondylodiscitis was radioclinical and laboratory-based. Results: 83 (49 women, 34 men) of the 1281 patients (6.48%) examined had infectious spondylodiscitis. The mean age at consultation was 70.59 ± 5.09 years, and the mean duration of the clinical course was 12 months. Spondylodiscitis was of tuberculous etiology (89.20%). It was most often found in the lumbar (56.62%) and dorsal (21.69%) segments. The location was multifocal in 12.05% of cases. It was associated with pulmonary involvement in 22.64% of cases. A neurological complication was identified in 48.19%. The main risk factors identified were promiscuity (48.82%), chronic alcoholism (18.07%), HIV infection (8.43%), diabetes (6.03%) and sickle cell disease (6.03%). The clinical course under medical treatment was favorable in 57 patients (68.68%). Conclusion: Infectious spondylodiscitis remains a frequent reason for hospitalization, tuberculosis being the most frequent etiology. Multifocal location, deterioration of general condition, gibbosity and neurological complications are exclusive to the elderly subject.

关键词： Infection Tuberculosis Spondylodiscitis Aging Sub-Saharan Africa

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培育应对21世纪气候变化的“聪明”作物

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湖南农业科学 2013年第8期 36-38页

作者： Chikelu mba Elcio P Guimaraes Kakoli Ghosh 卢红玲朱亚辉刘青山 Plant Genetic Resources and Seeds Team Plant Production and Protection DivisionFood and Agriculture Organization of the United NationsRomeItaly International Centre for Tropical Agriculture CaliColombia 湖南省农业信息与工程研究所长沙师范学校

据联合国粮农组织估计,到2050年,全球粮食需增产超过70%才能满足地球上90亿人口的刚性需求。但是,实现这一增长目标受到了诸多限制:一方面,为解决人口增长带来的食物需求问题,粮食产量年增幅需达到37%以上,而这一问题在贫穷的发展中国... 详细信息

据联合国粮农组织估计,到2050年,全球粮食需增产超过70%才能满足地球上90亿人口的刚性需求。但是,实现这一增长目标受到了诸多限制:一方面,为解决人口增长带来的食物需求问题,粮食产量年增幅需达到37%以上,而这一问题在贫穷的发展中国家尤为突出。另一方面,强降水、热浪、海平面升高等现象在世界多地发生,产生了洪水、干旱、盐碱化等严重后果,这些极端天气频发严重制约了粮食的持续增产,继而威胁到全

关键词：作物作物品种亲缘种气候变化气候变动

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Chronic Inflammatory Rheumatic Diseases in Rheumatological Practice in Lomé(Togo)

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Open Journal of Rheumatology and Autoimmune Diseases 2022年第1期12卷 9-20页

作者： Kodjo Kakpovi Sadat Oniankitan Komi C. Tagbor Koulouktsoa Kondian Viwalé ES Koffi-Tessio Awaki-Esso Atake Lamine Mamadou Diallo Pahimi Yibe Erika Djougnwe mba Moubarak Tiadjeri Eyram fianyo Prénam Houzou Owonayo Oniankitan Moustafa Mijiyawa Rheumatology Department Regional Teaching Hospital of Kara Kara Togo Rheumatology Department University Teaching Hospital Sylvanus Olympio Lomé Togo Rheumatology Department Hospital of Be Lomé Togo Rheumatology Department University Teaching Hospital of Kara Kara Togo

Chronic inflammatory rheumatism is a pathology of variable frequency and severity with a significant impact on the socio-economic, personal and family level. Study Aim: To describe the epidemiological, clinical, laboratory, radiological, therapeutic and evolutive features of chronic inflammatory rheumatic diseases in rheumatological practice in Togo. Patients and Methods: This was a multicenter cross-sectional study conducted from January 2011 to December 2019 on patients examined in the three rheumatology departments in Lomé (Togo). Patients 18 years old and above who have presented joint pain with or without synovitis, and/or rachialgia (back pain) for at least three months were included. The diagnosis of chronic inflammatory rheumatic diseases was made according to international consensus criteria. Results: Out of the 20333 patients whose files were collected during our study period, 290 (1.43%) suffered from chronic inflammatory rheumatic diseases. There were 226 (77.93%) females and 64 (22.07%) males. The mean age of the patients was 42.79 ± 15.18 years. The mean duration of symptoms was 40.80 ± 54.09 months. Arthritis (67.24%) was the main reason for consultation, followed by joint pain (31.38%). rheumatoid arthritis (41.03%), unclassified chronic inflammatory rheumatic diseases (38.62%), spondyloarthropathies (15.17%) and systemic lupus erythematosus (2.41%) were the major clinical forms. The immunological tests performed in 13.79% of cases were positive in 52.94% of cases. Carpitis (57.55%) and diffuse osteoporosis (45.28%) were the commonest radiographic features of the hands. 289 patients (99.66%) received symptomatic treatments such as NSAIDs (73.36%) and corticosteroids (51.90%) and 90 patients (31.03%) were treated with synthetic DMARDs such as methotrexate (88.89%). The outcome was favorable in 27.93% of cases. Conclusion: Chronic inflammatory rheumatic diseases are common diseases in rheumatological practice in Togo that deserve special attention. The

关键词： Chronic Inflammatory Rheumatic Diseases Rheumatoid Arthritis Spondyloarthropathies Sub-Saharan Africa

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Systematic Review on the Epidemiology and Management of the Dry Eye Disease in Sub-Saharan francophone Africa

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Open Journal of Ophthalmology 2020年第4期10卷 323-331页

作者： Rodrigue Romuald Elien Gagnan Yan-zaou-tou Guirou Nouhoum Bakayoko Seydou Dicko Mahamat Adam Sissoko Modibo Sidibé Mohamed Kolé mbaïkoua Jean Michel Mananu Innocent Adubango Hann T. fadimé Sylla Aly Diabaté Nagnan Cheick Rahim Diarra Modibo Institute of Tropical Ophthalmology of Africa-Teaching Hospital (CHU-IOTA) Bamako Mali National University Hospital Center of Bangui-Teaching Hospital (CNHUB) Bangui Central African Republic National Reference-Teaching Hospital (CHU-RN) N’Djamena Republic of Chad Evangelical Medical Center of Nyankunde-Bunia Bunia Democratic Republic of Congo Donka University Hospital Center Donka Republic of Guinea Medical and Surgical Center of the Army Conackry Republic of Guinea

Introduction: Dry Eye Disease (DED) is a multifactorial affection of the tears and the ocular surface. Its prevalence in the world varies between 7% and 33%. To the best of our knowledge, the prevalence of DED in Subsaharan Francophone African countries is not yet known. The objectives of this systematic review were to determine the prevalence of DED, to identify the main risk factors for DED, and to determine the diagnostic and therapeutic management of DED in Subsaharan Francophone African countries. Methodology: This is a systematic review of articles, dealing with DED, published in English or French language from 2010 to 2020. The following key words (Prevalence OR Incidence OR Proportion OR Rate OR Frequency OR Epidemiology OR Distribution) AND (Risk Factors OR Influences) AND (Symptoms or Questionnaire) AND (Clinical Signs OR Clinical Tests) AND (Dry Eye Disease OR Dry Eye Syndrome) AND (Pharmacological Treatment OR Non-pharmacological Treatment OR Management) AND (Benin OR Burkina Faso OR Burundi OR Cameroon OR Cap-Green OR Central African Republic OR Congo OR Congo (Democratic Republic of) OR Ivory Coast OR Gabon OR Guinea OR Guinea-Bissau OR Equatorial Guinea OR Mali OR Madagascar OR Mauritius (island) OR Niger OR Rwanda OR Sao Tome and Principe OR Senegal OR Seychelles OR Chad OR Togo) in French and English were searched on Pubmed, Chocrane database, Google scholar and ICTRP. Articles in English and French were selected from 2010 to 2020. Results:font-family:Verdana;"> We selected 05 articles on the epidemiology and management of D

关键词： Dry Eye Disease (DED) Epidemiology Diagnosis Treatment Sub-Saharan francophone Africa

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实施供应链管理提高企业竞争力

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天津职业大学学报 2004年第1期13卷 38-40,44页

作者：刘鑫天津财经学院 2001级mba天津300222

供应链管理是当今国际盛行的管理方式之一,正在成为企业的一种重要的战略竞争资源。本文阐述了供应链的兴起、发展、演变的内涵及供应链系统应用所具有的优势,对提高我国企业竞争力具有一定的借鉴作用。

关键词：供应链管理企业管理核心竞争力价值链流程重组

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创伤患者急诊气管插管的成功分析：一个大型成年创伤转诊中心的10年经验

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麻醉与镇痛 2011年第4期7卷 35-40页

作者： Christopher T. Stephens, MD Stephanie Kahntroff, MD Richard P. Dutton, MD, mba 段怡(译) 李士通(校) Division of Trauma Anesthesiology Department of Anesthesiology University of Maryland School of Medicine Baltimore Maryland 不详

背景对于多数麻醉医师来讲急诊气道管理是必须掌握的一项重要技术，我们总结了一个一级创伤中心10年来的经验，评估创伤患者入院后24小时内气管插管的结果。方法通过该中心1996年7月至2006年6月的创伤登记、质量管理记录、收费系统记录... 详细信息

背景对于多数麻醉医师来讲急诊气道管理是必须掌握的一项重要技术，我们总结了一个一级创伤中心10年来的经验，评估创伤患者入院后24小时内气管插管的结果。方法通过该中心1996年7月至2006年6月的创伤登记、质量管理记录、收费系统记录，得出入院后1小时内、24小时内需要插管的患者人数，并且回顾每个气管切开患者的医疗记录，了解其特征和无法进行经口或经鼻插管的原因。结果所有插管都在一名处理创伤经验丰富的麻醉医师的指导下进行。研究期间，标准插管法为直接喉镜下快速诱导插管。入院后1小时内，6088名患者进行插管，其中21名患者（0．3％）最终行气管切开。入院后24小时内，累计32000名患者进行插管，共31名行气管切开。意外的困难气道是气管切开的主要因素。31名患者中有4名死于外伤，无人死于插管失败。结论由经验丰富的麻醉医师指导，直接喉镜下快速诱导气管插管是有效的急诊气道管理方法，以其为核心的急诊气道管理规则使得气道管理成功率很高。

关键词：急诊气管插管创伤患者气管切开患者气道管理转诊成年麻醉医师快速诱导插管

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