检索结果-南通市图书馆

Integrative Zoology 2024年第3期19卷 417-423页

作者： João Pedro Rueda fURLAN Micaela Santana RAMOS fábio parra sellera Irys Hany Lima GONZALEZ Patrícia Locosque RAMOS Eliana Guedes STEHLING Department of Clinical Analyses Toxicology and Food ScienceSchool of Pharmaceutical Sciences of Ribeirão PretoUniversity of São PauloRibeirão PretoBrazil Department of Internal Medicine School of Veterinary Medicine and Animal ScienceUniversity of São PauloSão PauloBrazil School of Veterinary Medicine Metropolitan University of SantosSantosBrazil Coordination of Wild fauna Secretary of EnvironmentInfrastructure and LogisticsSão PauloBrazil

Antimicrobial resistance(AMR)is a growing phenomenon that poses a major public health challenge worldwide(Dhingra et al.2020;Antimicrobial Resistance Collaborators 2022).The selective pressure exerted in clinical settings has contributed to the longlasting successful dissemination of multidrug-resistant(MDR)Gram-negative bacteria in these environments(Chia et al.2020).

关键词： multidrug clinical

Endoscopic treatment of scarred polyps with a non-thermal device(Endorotor):A review of the literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第12期30卷 1706-1713页

作者： Mariam Zaghloul Hameed Rehman Stefano Sansone Konstantinos Argyriou Adolfo parra-Blanco Department of Hepatology Gastroenterology and Infectious DiseasesKafrelsheikh UniversitKafr-Elshikh 33516Egypt Department of Gastroenterology Service Nottingham City Hospital CampusNottingham University Hospitals NHS TrustNottingham NG51PBUnited Kingdom Department of Gastroenterology University Hospital of LarissaLarissa 41334Greece NIHR Nottingham biomedical Research Centre Nottingham University Hospitals NHS Trust and University of NottinghamNottingham NG72UHUnited Kingdom

Endoscopic resection(ER)of colorectal polyps has become a daily practice in most endoscopic units providing a colorectal cancer screening program and requires the availability of local experts and high-end endoscopic *** procedures have evolved over the past few years from endoscopic mucosal resection(EMR)to more advanced techniques,such as endoscopic submucosal dissection and endo-scopic full-thickness *** resection and disease eradication are the ultimate goals of ER-based techniques,and novel devices have been developed to achieve these *** EndoRotor®Endoscopic Powered Resection System(Interscope Medical,Inc.,Northbridge,Massachusetts,United States)is one such *** EndoRotor is a powered resection tool for the removal of alimentary tract mucosa,including post-EMR persistent lesions with scarring,and has both CE Mark and fDA *** review covers available published evidence documenting the usefulness of EndoRotor for the management of recurrent colorectal polyps.

关键词： EndoRotor Scarred polyps Recurrent polyps Colorectal cancer Colorectal polyps

Breaking paradigms: Long non-coding RNAs forming gene fusions with potential implications in cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第3期11卷 311-323页

作者： David Sanchez-Marin Macrina Beatriz Silva-Cazares fany Iris Porras-Reyes Rebeca Garcia-Roman Alma D.Campos-parra Posgrado en Ciencias biologicas Facultad de MedicinaUniversidad Nacional Autonoma de MexicoCiudad de MexicoC.P.04360Mexico Unidad Academica Multidisciplinaria Region Altiplano Universidad Autonoma de San Luis Potost(UASLP)Carretera a Cedral Km 5+600Ejido San Jose de la TrojesMatehualaSan Luis PotosiC.P.78760Mexico Servicio de Anatomia Patologica Instituto Nacional de Cancerologia(INCan)Nino JesuisTlalpanCiudaddeMexicoC.P.14080Mexico Instituto de Salud Publica Universidad Veracruzana(UV)Av.Dr LuisDr.Castelazo Ayala s/nCol.Industrial AnimasXalapaVeracruzC.P.91190Mexico

Long non-coding RNAs(lncRNAs)are non-coding RNAs longer than 200 nucleotides with dynamic regulatory *** interact with a wide range of molecules such as DNA,RNA,and proteins to modulate diverse cellular functions through several mechanisms and,if deregulated,they can lead to cancer development and ***,it has been described that IncRNAs are susceptible to form gene fusions with mRNAs or other IncRNAs,breaking the paradigm of gene fusions consisting mainly of protein-coding ***,their biological significance in the tumor phenotype is still ***,their recent identification opens a new line of research to study their biological role in tumor-igenesis,and their potential as biomarkers with clinical relevance or as therapeutic *** present study aimed to review the IncRNA fusions identified so far and to know which of them have been associated with a potential *** address the current challenges to deepen their study as well as the reasons why they represent a future therapeutic window incancer.

关键词： Cancer Genefusions IncRNAs ncRNAs Therapy

A prototype for on-site generation of chlorinated disinfectant for use in rural aqueducts

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Water Science and Engineering 2024年第1期17卷 33-40页

作者： Diana Marcela Cuesta parra felipe Correa Mahecha Andrés felipe Rubio Pinzon Davidcamilo Ramirez Bustos Leonel Alveyro Teran Llorente Miguel fernando Jimenez Jimenez Chemical and Environmental Engineering Department Fundacion Universidad de AmericaBogota 117111Colombia Chemical Engineering Department Fundacion Universidad de AmericaBogota 117111Colombia Mecanical Engineering Department Fundacion Universidad de AmericaBogota 117111Colombia

Sodium hypochlorite has significant potential as a sanitation solution in hard-to-reach *** studies have investigated the optimal electrolysis parameters for its production with volumes greater than 1o *** study evaluated sodium hypochlorite production through electrolysis in a 22-L prototype and identified the optimal operating *** were performed using graphite electrodes with areas of 68.4 cm^(2) at the laboratory scale and 1865.0 cm^(2) at the prototype scale.A design for experiments with different operating times,chloride concentrations,and electric current intensities was *** optimal operating time,sodium chloride concentration,and current intensity at the laboratory scale were 120 min,150 g of chloride per liter,and 3 A,respectively,leading to the production of 5.02 g/L of the disinfectant with an energy efficiency of 12.21 mg of Cl_(2) per *** the prototype scale,the maximum sodium hypochlorite concentration of 3.99 g of chloride per liter was achieved with an operating time of 120 min,a sodium chloride concentration of 100 g of chloride per liter,and a current intensity of 70 A,reaching an energy efficiency of 42.56 mg of Cl_(2) per *** addition,this study evaluated the influences of the chloride concentration,current intensity,and operating time on the production of sodium hypochlorite at the two scales,and formulated the equations showing the trends of sodium hypochlorite production and energy efficiency in the electrochemical *** 22-L prototype model for production of this oxidizing substance is promising for disinfection of large volumes of water in areas that are difficult to access.

关键词： Disinfection Electrolysis Energy efficiency Optimization Sodium hypochlorite

WHICH IS THE USE Of SYSTEMS THEORY IN LITERATURE ANALYSIS？： THE DISCOVERY Of THE PLACE IN LA MANCHA IN DON QUIXOTE

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Systems Science and Systems Engineering 2017年第4期26卷 517-530页

作者： francisco parra-Luna Complutense University of Madrid Yucatan 26 28231 Las Rozas Spain

The use of systems theory to attempt to determine which ＂place in La Mancha＂ was the one whose name Cervantes could not quite recall in his universal novel, appears to be ordained to change certain attitudes towards science held in Cervanfine literature. The reason： after four centuries of literary analysis, systemic methodology has proven able to identify the famous ＂place＂ with acceptable accuracy. Nonetheless, certain reasonable doubts persist around the suitability of a strictly scientific analysis of literature. In light of those doubts, the present article aims primarily to facilitate critique both of the systemic approach adopted and its outcome.

关键词： Don Quixote place in La Mancha systems theory epistemological totality determinantvariables

Atomic-scale simulations of material behaviors and tribology properties for BCC metal film

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2016年第1期25卷 412-418页

作者： H D Aristizabal P A parra P Lopez E Restrepo-parra PCM Computational Applications Universidad Nacional de Colombia-Sede ManizalesA.A.127ManizalesColombi Universidad Cató1ica de Manizales A.A.357ManizalesColombia

This work has two main purposes：（i） introducing the basic concepts of molecular dynamics analysis to material scientists and engineers, and （ii） providing a better understanding of instrumented indentation measurements, presenting an example of nanoindentation and scratch test simulations. To reach these purposes, three-dimensional molecular dynamics （MD） simulations of nanoindentation and scratch test technique were carried out for generic thin films that present BCC crystalline structures. Structures were oriented in the plane （100） and placed on fCC diamond substrates. A pair wise potential was employed to simulate the interaction between atoms of each layer and a repulsive radial potential was used to represent a spherical tip indenting the sample. Mechanical properties of this generic material were obtained by varying the indentation depth and dissociation energy. The load-unload curves and coefficient of friction were found for each test; on the other hand, dissociation energy was varied showing a better mechanical response for films that present grater dissociation energy. Structural change evolution was observed presenting vacancies and slips as the depth was varied.

关键词： molecular dynamics pair wise potential repulsive radial potential dissociation energy

维普期刊数据库

Envelopes of Commutative Rings

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2012年第3期28卷 561-580页

作者： Rafael parra Manuel SAORIN Departamento de Clculo. Escuela Bsica Facultad de Ingeniería Universidad de los Andes Departamento de Matemticas Universidad de Murcia

Given a significative class f of commutative rings, we study the precise conditions under which a commutative ring R has an S-envelope. A full answer is obtained when f is the class of fields, semisimple commutative rings or integral domains. When .f is the class of Noetherian rings, we give a full answer when the Krull dimension of R is zero and when the envelope is required to be epimorphic. The general problem is reduced to identifying the class of non-Noetherian rings having a monomorphic Noetherian envelope, which we conjecture is the empty class.

关键词： Noetherian ring envelope local ring artinian ring Krull dimension

维普期刊数据库

Air quality short-term control in an industrial region under adverse weather conditions

在线全文

学校读者我要写书评

暂无评论

Control Theory and Technology 2020年第3期18卷 257-268页

作者： Yuri SKIBA David parra-CUEVARA Center for Atmospheric Sciences National Autonomous University of MexicoCircuito ExteriorCiudad UniversitariaCDMX04510Mexico

A new short-term optimal control of air quality in an industrial region during atmospheric inversions is *** goal is to prevent violation of health standard of air quality in a few monitored *** control establishes restrictions on the emission rates of industrial sources and includes the identification of the industrial sources violating(exceeding)the emission rates set by the *** control and identification are based on using solutions to an adjoint dispersion *** that show the convergence of the emission rates,prescribed by the control,to the original emission rates of the industrial sources are given(Theorems 4 and 5).These results ensure that the new emission rates of industrial sources(established by the control)will be as close as possible to the original emission rates throughout the entire period of application of the *** creates the minimum possible restrictions on the functioning of industrial *** highlight of the new control is the possibility of selecting special weights for each pollution source in the goal function that is *** weights are mainly aimed at reducing the intensity of emissions of the main sources of *** example demonstrates the ability of the new method.A similar approach can also be used to develop methods for cleaning water zones polluted by oil(the problem of bioremediation),and to prevent excessive pollution of urban areas with automobile emissions.

关键词： Dispersion model adjoint model adjoint estimates optimal control source detection

Patent foramen ovale closure in non-lacunar cryptogenic ischemic stroke:where are we now?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2021年第1期18卷 67-74页

作者： AdriàARBOIX Olga parra Josefina ALIÓ Cerebrovascular Division Department of NeurologyHospital Universitari del Sagrat CorUniversitat de BarcelonaBarcelonaCataloniaSpain Department of Pneumology Hospital Universitari del Sagrat CorUniversitat de BarcelonaBarcelonaCataloniaSpain Department of Cardiology Hospital Universitari de BellvitgeL’Hospitalet de LlobregatBarcelonaCataloniaSpain

Patent foram ovale(PfO)is the most common anatomical cause of an interarterial *** is usually asymptomatic but may cause paradoxical embolism and is a risk factor for non-lacunar cryptogenic cerebral ischemia in young *** the first clinical trials did not show a significant superiority of PfO closure in the secondary prevention of cerebral ischemia as compared with standard antithrombotic treatment,six subsequent randomized clinical trials(CLOSURE I,PC Trial,RESPECT,CLOSE,REDUCE,and DEfENSE-PfO)performed in a sample of cryptogenic stroke in patients aged 60 years or younger provided evidence of a significant reduction of recurrent cerebral ischemia after percutaneous PfO ***,the use of percutaneous PfO closure cannot be generalized to the entire population of patients with cerebral ischemia and PfO,but it is indicated in highly selected patients with non-lacunar cryptogenic cerebral infarction with a large right-to-left shunt,an atrial septal aneurysm and no evidence of atrial fibrillation,as well as in association with antithrombotic treatment for an optimal secondary prevention of cerebral ischemia.

关键词： PfO Patent foramen ovale closure in non-lacunar cryptogenic ischemic stroke where are we now

维普期刊数据库

In-hand manipulation of a circular dynamic object by soft fingertips without angle measurement

在线全文

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2021年第5期64卷 193-208页

作者： R.GARCIA-RODRIGUEZ V.parra-VEGA Aeronautical Engineering Program and Postgraduate Program in Aerospacial Engineering Universidad Politecnica Metropolitana de Hidalgo Robotics and Advanced Manufacturing Department Research Center for Advanced Studies (CINVESTAV)

A multi-fingered robotic hand with curved fingertips enables contact re-positioning without reattaching at the expense of fingertip rolling. This rolling stands for a characteristic that facilitates dexterous manipulation but results in an algebraically complex dynamic model subject to such constraints. The hemispherical shape of fingertips allows a dexterous manipulation when controlling the tangent forces, which are essential to rotate object. However, the measurement of the object angle in practice requires tactile-optical sensing. In this paper, considering robotic fingers with curved soft tips, we propose a feedback control that ensures optimal dynamical grasping of a circular rigid object. It is shown that the collaboration of the contact forces, to get a minimum pose of internal forces, and the tangential forces, to induce the conditions for assuring the grasp closure, is necessary to get a skillful manipulation. In this case, the orientation control of a circular object to the desired angle while avoiding direct measurement of the object angle is presented. Stability conditions of the system are presented in the sense of stability-in-the-manifold. finally, representative simulations are shown and discussed.

关键词： optimal grasping manipulation soft-fingertips circular object stability-in-the-manifold