检索结果-南通市图书馆

A genome-wide scan for pleiotropy between bone mineral density and nonbone phenotypes

Bone Research 2020年第3期8卷 356-364页

作者： Maria A.Christou Georgios ntritsos Georgios Markozannes Fotis Koskeridis Spyros n.nikas David Karasik Douglas P.Kiel evangelos evangelou evangelia e.n.zan. Department of Hygiene and epidemiology Clinical and Molecular Epidemiology UnitSchool of MedicineUniversity of loanninaloanninaGreece Department of Medicine Beth Israel Deaconess Medical CenterHarvard Medical SchoolHinda and Arthur Marcus Institute for Aging ResearchHebrew SeniorLifeand the Broad Institute of MIT&HarvardCambridgeMAUSA Azrieli Faculty of Medicine Bar llan UniversitySafedIsrael Department of epidemiology and Biostatistics Imperial College LondonLondonUK Department of Health Services Policy and PracticeCenter for Research Synthesis in HealthSchool of Public HealthBrown UniversityProvidenceRlUSA

Osteoporosis is the most common metabolic bone disorder globally and is characterized by skeletal fragility and microarchitectural *** pleiotropy occurs when a single genetic element is associated with more than one *** aimed to identify pleiotropic loci associated with bone mineral density(BMD)and nonbone phenotypes in genome-wide association *** the discovery stage,the nHGRI-eBI Catalog was searched for genome-wide significant associations(P valueexcluding bone-related *** was used to identify proxies of the significantly associated single nucleotide polymorphisms(SnPs)(r2=1).We then assessed putative genetic associations of this set of SnPs with femoral neck(Fn)and lumbar spine(LS)BMD data from the GeFOS *** variants were claimed at a false discovery raten-BMD andese genetic markers was performed among more than 400000 UK Biobank participants of european ancestry with available genetic and heel bone ultrasound *** the discovery stage,72 BMD-related pleiotropic SnPs were identified,and 12 SnPs located in 11 loci on 8 chromosomes were replicated in the UK *** SnPs were associated,in addition to BMD,with 14 different *** pleiotropic associations were exhibited by rs479844(AP5B1,O V O L 1 genes),which was associated with dermatological and allergic diseases,and rs4072037(M U C 1 gene),which was associated with magnesium levels and gastroenterological *** conclusion,12 BMD-related genome-wide significant SnPs showed pleiotropy with nonbone *** associations can deepen the genetic understanding of bone-related diseases by identifying shared biological mechanisms with other diseases or traits.

关键词： magnesium globally Replication

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

effects of water,fertilizer,dissolved oxygen and temperature coupling on the photosynthesis,quality and yield of lettuce

引用

International Journal of Agricultural and Biological engineering 2023年第5期16卷 132-141页

作者： zan Ouyang Juncang Tian College of Water Resources and Civil engineering Hunan Agricultural UniversityChangsha 410128China School of Civil and Hydraulic engineering Ningxia UniversityYinchuan 750021China engineering and Technology Research Center of Water-Saving Irrigation and Water Resource Regulation in ningxia Ningxia UniversityYinchuan 750021China engineering Research Center for efficient Utilization of Water Resources in Modern Agricultural in Arid Regions Ministry of EducationYinchuan 750021China

With the increased demand for vegetables of nutritional value,enhancing vegetable quality while pursuing high yield has become a goal of many *** the present study,the effects of irrigation quota(A),fertilizer amount(B),dissolved oxygen(DO,C),and temperature in the climate chamber(D)applied in combination with the quality and yield of lettuce were ***-factor and three-level orthogonal designs were used to determine the single-factor trend,the sequence of primary and secondary influencing factors,and optimal regulatory measures concerning the *** order of the primary and secondary effects on the plant height,net photosynthesis rate(P_(n)),transpiration rate(e),vitamin C content(V_(c)),soluble protein content(S_(p)),dry matter accumulation(Dm),yield,irrigation water use efficiency(IWUe)of the lettuce plants followed the order A>B>D>*** addition,the order of the primary and secondary effects on the intercellular carbon dioxide concentration(C_(i)),chlorophyll content,and nitrate content followed the order A>D>B>*** optimum scheme for lettuce was A3B2C1D3(irrigation quota of 69 mm;fertilizer amount of 1.30 g/pot;DO of 6.5 mg/L;and temperature in the climate chamber of 20℃).Under the coordinated regulation of water,fertilizer,air,and temperature,the quality and yield of lettuce have been significantly *** study had important reference significance for the comprehensive regulation of water,fertilizer,air,and temperature facilities for vegetables.

关键词： Aerated irrigation Increased-temperature irrigation Growth Photosynthesis Dry matter accumulation Principal component analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

effects of fluoride on the removal of cadmium and phosphate by aluminum coagulation

引用

Journal of environmental Sciences 2015年第6期27卷 118-125页

作者： Ruiping Liu Bao Liu Lijun Zhu zan He Jiawei Ju Huachun Lan Huijuan Liu Key Laboratory of Drinking Water Science and Technology Research Center for Eco-Environmental Sciences Chinese Academy of Sciences University of Chinese Academy of Sciences

This study focuses on the effects of p H and fluoride at different molar ratios of fluoride to Al（R F：Al） on the removal of cadmium（Cd^（2＋）） and phosphate by Al coagulation. Fluoride at R F：Al≥ 3：1 inhibits the removal of Cd over wide Al dose ranges from 5 to 10 mg/L as Al. The removal of phosphate decreases significantly at high R F：Al of 10：1 whereas at lowered R F：Al（i.e., ≤ 6：1）, an adverse effect is observed only at insufficient Al doses below 2 mg/L. Fluoride shows inhibitive effects towards the removal of Cd at p H 7 and 8 and that of phosphate at p H 6. Fluoride decreases the ζ-potential in both systems, and the decreasing extent is positively correlated to the elevated R F：Al. The Al fluoride interactions include the formation of Al-F complexes and the adsorption of fluoride onto Al（OH）3 precipitates, i.e., the formation of Al（OH）n F m. Al-F complex formation inhibits Al hydrolysis and increases residual Al levels, and a more significant increase was observed at lower p H. Al-F complexes at high R F：Al complicate the coagulation behavior of Al towards both negative and positive ionic species. Moreover, fluoride at low R F：Al shows little effect on Al coagulation behavior towards Cd^2＋and phosphate, and the spent defluoridation adsorbent,i.e., aluminum（Al） hydro（oxide） with adsorbed fluoride at R F：Al of below 0.1：1, may be reclaimed as a coagulant after being dissolved.

关键词： Fluoride Aluminum coagulation Al-F complexes ζ-Potential Adsorbent reclamation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Chemical characterisation of particulate matter in urban transport modes

引用

Journal of environmental Sciences 2021年第2期33卷 51-61页

作者： Vania Martins Carolina Correia Ines Cunha-Lopes Tiago Faria evangelia Diapouli Manousos Ioannis Manousakas Konstantinos eleftheriadis Susana Marta Almeida Centro de Ciencias e Tecnologias n ucleares Instituto Superior TecnicoLisbonPortugal Institute of nuclear and Radiological Sciences and Technology Energy and SafetyN.C.S.R.'Demokritos'AthensGreece

Traffic is a main source of air pollutants in urban areas and consequently daily peak exposures tend to occur during *** exposure to particulate matter(PM)was monitored while cycling and travelling by bus,car and metro along an assigned route in Lisbon(Portugal),focusing on PM_(2.5) and PM_(1)0(PM with aerodynamic diameternd 10μm,respectively)mass concentrations and their chemical *** vehicles,the indoor-outdoor interplay was also *** PM_(2.5) mean concentrations were 28±5,31±9,34±9 and 38±21μg/m 3 for bus,bicycle,car and metro modes,*** carbon concentrations when travelling by car were 1.4 to 2.0 times higher than in the other transport modes due to the closer proximity to exhaust *** are marked differences in PM chemical composition depending on transport *** particular,Fe was the most abundant component of metro PM,derived from abrasion of rail-wheel-brake *** concentrations of Zn and Cu in cars and buses were related with brake and tyre wear particles,which can penetrate into the *** the motorised transport modes,Fe,Zn,Cu,ni and K were correlated,evidencing their common traffic-related *** average,the highest inhaled dose of PM_(2.5) was observed while cycling(55μg),and the lowest in car travels(17μg).Cyclists inhaled higher doses of PM_(2.5) due to both higher inhalation rates and longer journey times,with a clear enrichment in mineral *** presented results evidence the importance of considering the transport mode in exposure assessment studies.

关键词： Traffic Commuting Air pollution Particle chemistry Indoor-outdoor interplay Inhaled dose

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Probing the active sites of 2D nanosheets with Fe-n-C carbon shell encapsulated Fe_(x)C/Fe species for boosting sodium-ion storage performances

引用

nano Research 2022年第8期15卷 7154-7162页

作者： Huicong Xia Pengfei Yuan Lingxing zan Gan Qu Yunchuan Tu Kaixin Zhu Yifan Wei Zeyu WeiFangying Zheng Mo Zhang Yongfeng Hu Dehui Deng Jianan Zhang College of Materials Science and engineering Zhengzhou UniversityZhengzhou 450001China State Key Laboratory of Catalysis iChEMDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China College of Physics and engineering Zhengzhou UniversityZhengzhou 450001China College of Chemistry and Chemical engineering Xiamen UniversityXiamen 361005China Key Laboratory of Chemical Reaction engineering of Shaanxi Province College of Chemistry&Chemical EngineeringYan’an UniversityYan’an 716000China Canadian Light Source 44 Innovation Boulevard SaskatoonSaskatoon S7N 2V3Canada

Developing stable but high active metal-nitrogen-carbon(M-n-C)-based hard carbon anode is a promising way to be the alternatives to graphene and blank hard carbon for sodium-ion batteries(SIBs),requiring the precise tailoring of the electronic structure for optimizing the na+intercalation behavior,yet is greatly ***,Fe-n-C graphitic layer-encapsulating Fe3C species within hard carbon nanosheets(Fe-n-C/Fe3C@HCns)are rationally engineered by pyrolysis of self-assembled ***,the Fe-n-C/Fe3C@HCns exhibit outstanding rate capacity(242 mAh·g^(−1)at 2,000 mA·g^(−1)),which is 2.1 and 4.2 times higher than that of Fe-n-C and n-doped carbon(n-C),respectively,and prolonged cycling stability(176 mAh·g^(−1)at 2,000 mA·g^(−1)after 2,000 cycles).Theoretical calculations unveil that the Fe3C species enhance the electronic transfer from na to Fe-n-C,resulting in the charge redistribution between the interfaces of Fe3C and ***,the optimized adsorption behavior towards na+reduces the thermodynamic energy *** synergistic effect of Fe3C and Fe-n-C species maintains the structural integrity of electrode materials during the sodiation/desodiation *** in-depth insight into the advanced na+storage mechanisms of Fe3C@Fe-n-C offers precise guidance for the rational establishment of confinement heterostructures in SIBs.

关键词： Fe-n-C/Fe3C species encapsulated carbon nanosheets sodium-ion storage density functional theory

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Willingness of Greek general population to get a COVID-19 vaccine

引用

Global Health Research and Policy 2021年第1期6卷 478-487页

作者： Georgia Kourlaba eleni Kourkouni Stefania Maistreli Christina-Grammatiki Tsopela nafsika-Maria Molocha Christos Triantafyllou Markela Koniordou Ioannis Kopsidas evangelia Chorianopoulou Stefania Maroudi-Manta Dimitrios Filippou Theoklis e.Zaoutis Center for Clinical epidemiology and Outcomes Research(CLeO) AthensGreece eCOnCARe LP AthensGreece Department of Anatomy and Surgical Anatomy Medical SchoolNational and Kapodistrian University of AthensAthensGreece Division of Infectious Diseases The Children’s Hospital of PhiladelphiaPerelman School of Medicine at the University of PennsylvaniaPhiladelphiaUSA

Background:epidemiological data indicate that a large part of population needs to be vaccinated to achieve herd ***,it is of high importance for public health officials to know whether people are going to get vaccinated for *** objective of the present study was to examine the willingness of adult residents in Greece to receive a COVID-19 ***:A cross-sectional was survey conducted among the adult general population of Greece between April 28,2020 to May 03,2020(last week of lockdown),using a mixed methodology for data collection:Computer Assisted Telephone Interviewing(CATI)and Computer Assisted web Interviewing(CAWI).Using a sample size calculator,the target sample size was found to be around 1000 *** ensure a nationally representative sample of the urban/rural population according to the Greek census 2011,a proportionate stratified by region systematic sampling procedure was used to recruit *** collection was guided through a structured *** willingness to COVID-19 vaccination,participants were asked to answer the following question:“If there was a vaccine available for the novel coronavirus,would you do it?”Results:Of 1004 respondents only 57.7%stated that they are going to get vaccinated for *** aged>65 years old,those who either themselves or a member of their household belonged to a vulnerable group,those believing that the COVID-19 virus was not developed in laboratories by humans,those believing that coronavirus is far more contagious and lethal compared to the H1n1 virus,and those believing that next waves are coming were statistically significantly more likely to be willing to get a COVID-19 *** knowledge score regarding symptoms,transmission routes and prevention and control measures against COVID-19 was significantly associated with higher willingness of respondents to get ***:A significant proportion of individuals in the general popu

关键词： Vaccine hesitancy COVID-19 europe Vaccine coverage

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fundamental research on the size and velocity measurements of coal powder by trajectory imaging

引用

Journal of Zhejiang University-Science A(Applied Physics & engineering) 2013年第5期14卷 377-382页

作者： Xue-cheng WU Ying-chun WU Cong-chang ZHAnG Guo-neng LI Qun-xing HUAnG Ling-hong CHen Kun-zan QIU Hao ZHOU Ke-fa Cen State Key Laboratory of Clean energy Utilization Zhejiang University Institute for new energy and energy Saving Technology Zhejiang University of Science and Technology

A trajectory imaging based method for measuring the velocity and diameter of coal particles was *** using an industrial charge-coupled device(CCD)camera and a low power semiconductor laser,the images of coal particles under relatively long exposure time were recorded and then processed to yield both the velocities and *** research on this method with special attention to recording parameters,e.g.,magnification factor and exposure time,was carried *** most of the test cases,the results agree with those obtained by particle image velocimetry(PIV)and shadow imaging *** with good accuracy can be obtained when the imaging magnification factor and exposure time are set appropriately,making n be larger than 3.5,and R between 5-7,where n and R are the number of pixels occupied by the average width and the ratio of length to width of particle trajectory on the image,*** work indicates the feasibility and potential application of the present measurement method for online measurement of coal powder in pipes in industrial power plants.

关键词： Trajectory imaging Velocity measurement Size measurement Coal powder

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

论Rossby波在东、西风带中传播与频散Ⅱ--球面Rossby波方程与诊断分析

引用

热带气象学报 2016年第5期32卷 622-633页

作者：辜旭赞中国气象局武汉暴雨研究所湖北武汉430074

从球坐标(Spherical coordinate)非地转、正压水平无辐散大气运动微扰方程出发,推导出球面Rossby波方程,证明球面Rossby波的物理机制仍然是绝对涡度守恒与卢效应,但基本气流以涡度形式参与了卢效应。因球面Rossby波偏微分方程不存在经向... 详细信息

从球坐标(Spherical coordinate)非地转、正压水平无辐散大气运动微扰方程出发,推导出球面Rossby波方程,证明球面Rossby波的物理机制仍然是绝对涡度守恒与卢效应,但基本气流以涡度形式参与了卢效应。因球面Rossby波偏微分方程不存在经向-纬向传播的"双向简谐波(传统Rossby波)"解,则将它做经向-纬向求导分离,从而得到关于球面经向风扰动的二阶偏微分方程及与之相应的仅作纬向传播的简谐波解,但待解的二阶偏微分方程不归于数理方程中的任何特殊函数,即证明不存在以连带Legendre函数为通解的Haurwitz波。采用传统Rossby波两个通解,当作球面Rossby波两类特解,做诊断分析表明,传统Rossby波正确反映球面Rossby波的(β-平面近似)"线性部分",但球面Rossby波及其纬向波速和群速都带有地球曲率性,并且存在奇点,其中,球面谐波扰动Rossby波仍然保持槽与脊纬向对称性,但"正弦扰动"与"余弦扰动"Rossby波有一定差别,而球面指数扰动Rossby波槽与脊不具备纬向对称性,后者可以解释东、西风带槽与脊一般为纬向非对称,还可以解释台风的纬向非对称结构。

关键词： Rossby波 Haurwitz波微扰方程二阶偏微分方程谐波扰动解指数扰动解 β效应

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Genome-wide detection of selective signatures in a Duroc pig population

引用

Journal of Integrative Agriculture 2018年第11期17卷 2528-2535页

作者： DIAO Shu-qi LUO Yuan-yu MA Yun-long DenG Xi He Ying-ting GAO ning ZHAnG Hao LI Jia-qi CHen zan-mou ZHAnG Zhe Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding/national engineering Research Centre for Breeding Swine Industry/College of Animal Science South China Agricultural University Guangzhou 510642 P.R.China Liupanshui Academy of Agricultural Sciences Liupanshui 553001 P.R. China Key Laboratory of Agricultural Animal Genetics Breeding and Reproduction Ministry of Education/College of Animal Sciences and Technology Huazhong Agricultural University Wuhan 430070 P.R. China

The Duroc pig has high adaptability and feeding efficiency, making it one of the most popular pig breeds worldwide. Over long periods of natural and artificial selection, genetic footprints, i.e., selective signatures, were left in the genome. In this study, a Duroc pig population （n=715） was genotyped with the Porcine SnP60K Bead Chip and the GeneSeek Genomic Profiler （GGP） Porcine Chip. The relative extended haplotype homozygosity （ReHH） method was used for selective signature detection in a subset of the population （n=368）, selected to represent a balanced family structure. In total, 154 significant core regions were detected as selective signatures （,P〈0.01）, some of which overlap with previously reported quantitative trait loci associated with several economically important traits, including average daily gain and backfat thickness. Genome annotation for these significant core regions revealed a variety of interesting candidate genes including GATA3, TAF3, ATP5C1, and FGFI. These genes were functionally related to anterior/posterior pattern specification, phosphatidylinositol 3-kinase signaling, embryonic skeletal system morphogenesis, and oxidation-reduction processes. This research provides knowledge for the study of selection mechanisms and breeding practices in Duroc and other pigs.

关键词： Duroc selective signature candidate genes ReHH

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

高效液相色谱法-蒸发光散射检测器测定盾叶薯蓣中薯蓣皂苷的含量

引用

江西师范大学学报（自然科学版） 2007年第1期31卷 94-96页

作者：昝丽霞陕西理工学院生物科学与工程学院陕西汉中723001

建立以蒸发光散射检测器（eLSD）测定盾叶薯蓣中薯蓣皂苷含量的高效液相色谱分析方法,考察了不同产地盾叶薯蓣中薯蓣皂苷的含量.色谱柱为HiQsil C18柱（250 mm×4.6 mm,10μm）,流动相为乙腈-水（33∶67）,流速为0.8 mL/min,柱温为室温.... 详细信息

建立以蒸发光散射检测器（eLSD）测定盾叶薯蓣中薯蓣皂苷含量的高效液相色谱分析方法,考察了不同产地盾叶薯蓣中薯蓣皂苷的含量.色谱柱为HiQsil C18柱（250 mm×4.6 mm,10μm）,流动相为乙腈-水（33∶67）,流速为0.8 mL/min,柱温为室温.Alltech蒸发光散射检测器参数：载气为氮气,流速为2.5mL/min,漂移管温度为100℃,压力为0.45 Mpa.结果表明：薯蓣皂苷在0.35-3.48μg范围内有良好线性关系,r=0.9976,平均回收率为103.2%,RSD为1.61%（n=6）.该方法快速简便,灵敏度高,结果准确可靠,可用于盾叶薯蓣药材中薯蓣皂苷的分析及质量检测与控制.

关键词：盾叶薯蓣薯蓣皂苷高效液相色谱法蒸发光散射检测器

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：