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Ensure preparation and capsule endoscopy:A two-center prospective study

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World Journal of Gastroenterology 2013年第8期19卷 1264-1270页

作者： eva niv Baruch Ovadia Yulia Ron Ervin Santo Elisabeth Mahajna Zamir Halpern Zvi Fireman Department of Gastroenterology Tel Aviv Sourasky Medical CenterTel Aviv 64239Israel Department of Gastroenterology Hillel Yaffe Medical CenterHadera 38100Israel

AIM:To compare small bowel(SB) cleanliness and capsule endoscopy(CE) image quality following Ensure,polyethylene glycol(PEG) and standard ***:A preparation protocol for CE that is both efficacious and acceptable to patients remains *** the physiological function of the SB as a site for the digestion and absorption of food and not as a stool reservoir,preparation consisting of a liquid,fiber-free formula ingested one day before a CE study might have an advantage over other kinds of *** conducted a prospective,blind-topreparation,two-center study that compared four types of *** participants' demographic and clinical data were *** and SB transit times were *** presence of bile in the duodenum was scored by a single,blinded-to-preparation gastroenterologist expert in CE,as was cleanliness within the proximal,middle and distal part of the SB.A four-point scale was used(grade 1 = no bile or residue,grade 4 ≥ 90% of lumen full of bile or residual material).RESULTS:The 198 consecutive patients who were referred to CE studies due to routine medical reasons were divided into four *** all observed a 12-h overnight fast before undergoing *** the 24 h preceding the fast,control group 1(n = 45 patients) ate light unrestricted meals,control group 2(n = 81) also ate light meals but free of fruits and vegetables,the PEG group(n = 50) ate unrestricted light meals and ingested the PEG preparation,and the Ensure group(n = 22) ingested only the Ensure *** with Ensure improved the visualization of duodenal mucosa(a score of 1.76) by decreasing the bile content compared to preparation with PEG(a score of 2.9)(P = 0.053).Overall,as expected,there was less residue and stool in the proximal part of the SB than in the middle and distal parts in all *** total score of cleanliness throughout the length of the SB showed some benefit for Ensure(a score of 1.8) over control g

关键词： Capsule endoscopy Preparation Polyethylene glycol Ensure Fiber-free diet Image quality

Effect of erythromycin on image quality and transit time of capsule endoscopy: A two-center study

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World Journal of Gastroenterology 2008年第16期14卷 2561-2565页

作者： eva niv Ido Bogner Olga Barkey Zamir Halpern Elisabeth Mahajna Roman Depsames Yael Kopelman Zvi Fireman Department of Gastroenterology Hillel Yaffe Medical Center Department of Gastroenterology Tel Aviv Sourasky Medical Center

AIM: To compare the effect of oral erythromycin vs no preparation with prokinetics on the transit time and the image quality of capsule endoscopy (CE) in evaluating small bowel (SB) pathology. METHODS: We conducted a retrospective, blinded (to the type of preparation) review of 100 CE studies, 50 with no preparation with prokinetics from one medical center (Group A) and 50 from another center with administration of a single dose of 200 mg oral erythromycin 1 h prior to CE (Group B). Gastric, SB and total transit times were calculated, the presence of bile in the duodenum was scored, as was cleanliness within the proximal, middle and distal intestine. RESULTS: The erythromycin group had a slightly shorter gastric transit time (21 min vs 28 min, with no statistical significance). SB transit time was similar for both groups (all P > 0.05). Total transit time was almost identical in both groups. The rate of incomplete examination was 16% for Group A and 10% for Group B (P = 0.37). Bile and cleanliness scores in different parts of the intestine were similar for the two groups (P > 0.05). CONCLUSION: Preparation for capsule endoscopy with erythromycin does not affect SB or total transit time. It tends to reduce gastric transit time, but it does not increase the cecum-reaching rate. Erythromycin does not adversely affect image quality. We consider the routine use of oral erythromycin preparation as being unjustified, although it might be considered in patients with known prolonged gastric emptying time.

关键词： Capsule endoscopy Gastric transit time Small bowel transit time Erythromycin Image quality

Non-invasive versus invasive mechanical ventilation for respiratory failure in severe acute respiratory syndrome

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中华医学杂志(英文版) 2005年第17期 7-15页

作者： Loretta YC Yam,Alfred YF Chan,Thomas MT Cheung,eva LH Tsui,Jane CK Chan,Vivian CW Wong Division of Respiratory and Critical Care Medicine Department ofMedicine Pamela Youde Nethersole Eastern Hospital Hong Kong China Division of Respiratory and Critical Care Medicine Department ofMedicine Pamela Youde Nethersole Eastern Hospital Hong Kong China Division of Respiratory and Critical Care Medicine Department ofMedicine Pamela Youde Nethersole Eastern Hospital Hong Kong China Hong Kong Hospital Authority Head Office Hong Kong China Hong Kong Hospital Authority Head Office Hong Kong China Hong Kong Hospital Authority Head Office Hong Kong China

Background Severe acute respiratory syndrome is frequently complicated by respiratory failure requiringventilatory *** aimed to compare the efficacy of non-invasive ventilation against invasive mechanicalventilation treating respiratory failure in this *** Retrospective analysis was conducted on all respiratory failure patients identified from the HongKong Hospital Authority Severe Acute Respiratory Syndrome *** rate, mortality and secondaryoutcome of a hospital utilizing non-invasive ventilation under standard infection control conditions ( nivHospital) were compared against13 hospitals using solely invasive ventilation (IMVHospitals).Multiple logisticregression analyses with adjustments for confounding variables were performed to test for association betweenoutcomes and hospital *** Both hospital groups had comparable demographics and clinical profiles, but niv Hospital (42patients) had higher lactate dehydrogenase ratio and worse radiographic score on admission and ribavirin-corticosteroid *** to IMV Hospitals (451 patients), niv Hospital had lower adjustedodds ratios for intubation (0.36, 95% CI 0.164 -0.791,P=0.011) and death (0.235, 95% CI 0.077 -0.716,P=0.011), and improved earlier after pulsed steroid *** were no instances of transmission ofsevere acute respiratory syndrome among health care workers due to the use of non-invasive *** Compared to invasive mechanical ventilation, non-invasive ventilation as initial ventilatory supportfor acute respiratory failure in the presence of severe acute respiratory syndrome appeared to be associated withreduced intubation need and mortality.

关键词： acute respiratory failure · infection control · invasive mechanical ventilation · non-invasive ventilation · severe acute respiratory syndrome

Non-invasive versus invasive mechanical ventilation for respiratory failure in severe acute respiratory syndrome

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Chinese Medical Journal 2005年第17期118卷 1413-1421页

作者： Loretta YC Yam Alfred YF Chan Thomas MT Cheung eva LH Tsui Jane CK Chan Vivian CW Wong Division of Respiratory and Critical Care Medicine Department of MedicinePamela Youde Nethersole Eastern HospitalHong KongChina Hong Kong Hospital Authority Head Office Hong KongChina

Background Severe acute respiratory syndrome is frequently complicated by respiratory failure requiring ventilatory *** aimed to compare the efficacy of non-invasive ventilation against invasive mechanical ventilation treating respiratory failure in this *** Retrospective analysis was conducted on all respiratory failure patients identified from the Hong Kong Hospital Authority Severe Acute Respiratory Syndrome *** rate,mortality and secondary outcome of a hospital utilizing non-invasive ventilation under standard infection control conditions(niv Hospita1)were compared against 13 hospitals using solely invasive ventilation(IMV Hospitals).Multiple logistic regression analyses with adjustments for confounding variables were performed to test for association between outcomes and hospital *** Both hospital groups had comparable demographics and clinical profiles,but niv Hospital(42 patients)had higher lactate dehydrogenase ratio and worse radiographic score on admission and ribavirin-corticosteroid *** to IMV Hospitals(451 patients).niv Hospital had lower adjusted odds ratios for intubation(0.36,95%C10.164-0.791,P=0.011)and death(0.235.95%C10.077-0.716,P=0.O 11),and improved earlier after pulsed steroid *** were no instances of transmission of severe acute respiratory syndrome among health care workers due to the use of non-invasive *** Compared to invasive mechanical ventilation,non-invasive ventilation as initial ventilatory support for acute respiratory failure in the presence of severe acute respiratory syndrome appeared to be associated with reduced intubation need and mortality.

关键词： acute respiratory failure infection control invasive mechanical ventilation non-invasive ventilation severe acute respiratory syndrome