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Analysis of optical emission spectroscopy data during silicon etching in SF_(6)/O_(2)/Ar plasma

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Plasma Science and Technology 2021年第12期23卷 117-127页

作者： Dong Hwan KIM jeong eun choi Sang Jeen HONG Department of Electronics Engineering Myongji University116 Myongji-roYongin-siGyeonggi-doRepublic of Korea

Silicon etching is an essential process in various applications,and a major challenge for etching process is anisotropic high aspect ratio etching *** etch profile is determined by the plasma parameters and process *** this study,the plasma state with each process parameters were analyzed through the optical emission spectroscopy(OES)plasma diagnostic sensor by both chemical and physical *** temperature and electron density were additionally acquired using the corona model with OES data that provides chemical species information,and the etch profile was evaluated through scanning electron microscope measurement *** results include changes in profile with gas ratio,bias power,and *** figure out that factors like ion energy and ion angular distribution as well as chemical reaction affect the anisotropic profile.

关键词： silicon etching profile optical emission spectroscopy plasma in-formation corona model

Role of multidetector computed tomography in patients with acute infectious colitis

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World Journal of Clinical Cases 2022年第12期10卷 3686-3697页

作者： Seung Jung Yu Jae Hyuk Heo eun jeong choi Jong Hyuk Kim Hong Sub Lee Sun Young Kim Jae Hoon Lim Department of Internal Medicine Inje University Busan Paik HospitalBusan 47392South Korea Department of Radiology Myongji HospitalHanyang University College of MedicineGoyang 10475South Korea Department of Cancer Control and Population Health National Cancer CenterGoyang 10408South Korea

BACKGROUND The role of multidetector computed tomography(MDCT)in patients with acute infectious colitis is still *** To examine the usefulness of MDCT in distinguishing the etiology of acute infectious *** Overall,244 patients who met the criteria for acute infectious colitis and visited the Hospital from February 2015 to 2018 were retrospectively enrolled and divided into two groups(bacterial:204,viral:40)according to causes of acute colitis,based on stool *** MDCT parameters,including wall thickening,submucosal edema,mucosal enhancement,serosa involvement,empty colon sign,small bowel involvement,comb sign,continuous distribution,accordion sign,mucosal thickening,and lymph node enlargement,were constructed in a blinded *** MDCT parameters of wall thickening(OR:13.60;95%CI:5.80–31.88;P<0.001),submucosal edema(OR:36.08;95%CI:13.54–96.13;P<0.001),mucosal enhancement(OR:22.55;95%CI:9.28–54.81;P<0.001),serosal involvement(OR:14.50;95%CI:3.33–63.23;P<0.001),empty colon sign(OR:6.68;95%CI: 2.44–18.32;P < 0.001), continuous distribution (OR: 24.09;95%CI: 9.38–61.90;P < 0.001), accordionsign (OR: 9.02;95%CI: 1.12–72.35;P = 0.038), mucosal thickening (OR: 46.41;95%CI: 10.38–207.51;P< 0.001), and lymph node enlargement (OR: 4.39;95%CI: 1.22–15.72;P = 0.023) were significantlyassociated with bacterial colitis. At least one positive finding in four CT outcomes (submucosaledema, mucosal enhancement, continuous distribution, mucosal thickening) in summer showed ahigh probability of bacterial colitis (sensitivity, 41.67;specificity, 92.50;OR: 24.95).CONCLUSIONMDCT provides many clues that can be useful in suggesting a specific etiology of acute infectiouscolitis.

关键词： Colitis Multidetector computed tomography Differential diagnosis Bacterial infections Viral infections

Single-cell and spatial omics:exploring hypothalamic heterogeneity

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Neural Regeneration Research 2025年第6期20卷 1525-1540页

作者： Muhammad Junaid eun jeong Lee Su Bin Lim Department of Biochemistry&Molecular Biology Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Graduate School of Ajou UniversitySuwonSouth Korea Department of Brain Science Ajou University School of MedicineSuwonSouth Korea

Elucidating the complex dynamic cellular organization in the hypothalamus is critical for understanding its role in coordinating fundamental body functions. Over the past decade, single-cell and spatial omics technologies have significantly evolved, overcoming initial technical challenges in capturing and analyzing individual cells. These high-throughput omics technologies now offer a remarkable opportunity to comprehend the complex spatiotemporal patterns of transcriptional diversity and cell-type characteristics across the entire hypothalamus. Current single-cell and single-nucleus RNA sequencing methods comprehensively quantify gene expression by exploring distinct phenotypes across various subregions of the hypothalamus. However, single-cell/single-nucleus RNA sequencing requires isolating the cell/nuclei from the tissue, potentially resulting in the loss of spatial information concerning neuronal networks. Spatial transcriptomics methods, by bypassing the cell dissociation, can elucidate the intricate spatial organization of neural networks through their imaging and sequencing technologies. In this review, we highlight the applicative value of single-cell and spatial transcriptomics in exploring the complex molecular-genetic diversity of hypothalamic cell types, driven by recent high-throughput achievements.

关键词： cellular diversity hypothalamus multi-omics single-cell transcriptomics spatial transcriptomics

Fermented Lysate of Lactiplantibacillus Isolated From Green Tea Leaves Protects Keratinocytes Against Stress Hormone and Staphylococcus Aureus

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China Detergent & Cosmetics 2021年第3期6卷 54-60页

作者： Kilsun Myoung eun-jeong choi Hanbyul Kim Hung Su Baek Hyoung-June Kim Won-Seok Park Hyunhee Kim Jaeho Yeon Research and Development Center AmorepacificKorea Amorepacific(Shanghai)R&I Center Co. Ltd.ChinaKilsun

Psychological stress can impair epidermal barrier function by inhibiting the proliferation and differentiation of *** this study,the effect of stress hormone on skin microorganisms was confirmed through an in vitro ***,a typical stress hormone,inhibited the growth of skin microbes,especially Staphylococcus epidermidis,which is a commensal skin *** cortisol enhanced the adhesion of the pathogenic bacterium Staphylococcus aureus to *** fermented lysate of Lactiplantibacillus isolated from green tea leaves(LFL)affected the growth of skin microbes in the opposite manner to cortisol,and increased the expression of a keratinocyte differentiation marker that was suppressed by cortisol and ***,LFL inhibited the adhesion of *** to *** modulating effect of LFL on the growth and adhesion of skin microbes was unaffected by the presence of *** also alleviated cell damage in reconstructed human epidermis caused by *** results suggest that LFL may be useful as a cosmetic ingredient capable of controlling skin microbiome balance and protecting skin health against psychological stress.

关键词： stress hormone skin microbiome lactobacillus ferment lysate

Effect of music on colonoscopy performance: A propensity scorematched analysis

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World Journal of Gastrointestinal Endoscopy 2023年第5期15卷 397-406页

作者： eun jeong choi Sam Ryong Jee Sang Heon Lee Jun Sik Yoon Seung Jung Yu Jong Hyun Lee Han Byul Lee Sang Wook Yi Myeong Pyo Kim Byung Cheol Chung Hong Sub Lee Department of Internal Medicine Inje University College of MedicineBusan Paik HospitalBusan 47392South Korea Department of Public Health Ajou University Graduate School of Public HealthSuwon 16499South Korea Department of Preventive Medicine and Public Health Catholic Kwandong University College of MedicineGangneung 25601South Korea

BACKGROUND Music has been used to reduce stress and improve task performance during medical *** To assess the effects of music on colonoscopy performance *** We retrospectively reviewed patients who underwent colonoscopy performed by four endoscopists with popular *** performance outcomes,such as insertion time,adenoma detection rate(ADR),and polyp detection rate(PDR),were compared between the music and non-music *** reduce selection bias,propensity score matching was *** After one-to-one propensity score matching,169 colonoscopies were selected from each *** significant differences in insertion time(4.97 vs 5.17 min,P=0.795)and ADR(39.1%vs 46.2%,P=0.226)were found between the two *** analysis showed that the insertion time(3.6 vs 3.8 min,P=0.852)and ADR(51.1%vs 44.7%,P=0.488)did not significantly differ between the two groups in ***,in trainees,PDR(46.9%vs 66.7%,P=0.016)and ADR(25.9%vs 47.6%,P=0.006)were significantly lower in the music than in the nonmusic *** The current study found that listening to music during colonoscopy did not affect procedure ***,it suggested that music may distract trainees from appropriately detecting adenomas and polyps.

关键词： Music Colonoscopy Performance Adenoma Colonic polyps Cecal insertion time

Endothelial progenitor cell differentiation using cryopreserved,umbilical cord blood-derived mononuclear cells

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Acta Pharmacologica Sinica 2007年第3期28卷 367-374页

作者： Jun-ho JANG~(2,5) Sun-kyung KIM~(3,5) jeong-eun choi~3 Young-jin KIM~3 Hyun-woo LEE~2 Seok-yun KANG~2 Joon-seong PARK~2 Jin-hyuk choi~2 Ho-yeong LIM~4 Hugh C KIM~(2,6)2 Department of Hematalogy-Oncology,Ajou University,School of Medicine,Suwon 442749,Korea 3 Biomedical Research Institute,LifeCord,Suwon 442749,Korea 4 Division of Hematology-Ontology,Department of Medicine,Samsung Medical Center,Sungkyunkwan University School of Medicine,Seoul 135710,Korea Department of Hematology-Oncology Ajou University School of Medicine Suwon Korea Department of Biomedical Research Institute Suwon Korea Division of Hematology-Oncology Department of Medicine Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea

Aim:To investigate the endothelial differentiation potentiality of umbilical cordblood(UCB),we induced the differentiation of endothelial progenitor cells(EPC)from cryopreserved UCB-derived mononuclear cells(MNC).Methods:MNC fromcryopreserved UCB and peripheral blood(PB)were cultured in M199 medium withendothelial cell growth supplements for 14 *** were characterized by RT-PCR,flow cytometry,and immunocytochemistry *** proliferation of differen-tiated EPC was studied by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazoliumbromide(MTT)assay,and vascular endothelial growth factor(VEGF)concentra-tion was measured using an ELISA *** of UCB-derived EPC werecompared with those of PB-derived ***:A number of round-shapedcells were loosely attached to the bottom after 24 h culture,and numerous spindle-shaped cells began to appear from the round-shaped ones on d *** cellsexpressed endothelial markers such as,Flt-1/VEGFR-1,ecNOS,VE-cadherin,vonWillebrand factor,and secreted VEGE The patterns of endothelial markers of EPCfrom PB and UCB did not show striking *** results of the prolifera-tion and secretion of VEGF were also ***:We successfully cul-tured UCB cells stored at -196℃ into cells with the quality of endothelial *** EPC could be used for angiogenic therapeutics by activating adjacentendothelial cells and enhancing angiogenesis.

关键词： cord blood endothelial cells cryopreserved

Electrochemical processing of spent nuclear fuels:An overview of oxide reduction in pyroprocessing technology

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Progress in Natural Science:Materials International 2015年第6期25卷 572-582页

作者： eun-Young choi Sang Mun jeong Korea Atomic Energy Research Institute Department of Chemical Engineering Chungbuk National University

The electrochemical reduction process has been used to reduce spent oxide fuel to a metallic form using pyroprocessing technology for a closed fuel cycle in combination with a metal-fuel fast *** the electrochemical reduction process,oxides fuels are loaded at the cathode basket in molten LiO–LiCl salt and electrochemically reduced to the metal *** approaches based on thermodynamic calculations and experimental studies have been used to understand the electrode reaction and efficiently treat spent *** factors that affect the speed of the electrochemical reduction have been determined to optimize the process and scale-up the electrolysis *** addition,demonstrations of the integrated series of processes(electrorefining and salt distillation) with the electrochemical reduction have been conducted to realize the oxide fuel *** overview provides insight into the current status of and issues related to the electrochemical processing of spent nuclear fuels.

关键词： Pyroprocessing Electrochemical reduction Electrorefining Molten salt Spent oxide fuel

Reliable high temperature, high humidity flexible thin film encapsulation using Al2O3/MgO nanolaminates for flexible OLEDs

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Nano Research 2020年第10期13卷 2716-2725页

作者： Ki Suk Kang So Yeong jeong eun Gyo jeong Kyung Cheol choi School of Eetrical Enginerng Korea Advanced lstute of Sciencp and Tchcnoloy(KAIST) 291 Daehak roYuscong guDaejeon 34141Republic of Korea Department of Clothing and Textiles Chormam National University77 Yongbong.roBuk guGwangjiu 61186Republic of Korea

Since most organic materials are very sensitive to moisture and oxygen, organic light emitting diodes (OLEDs) require an encapsulation layer to protect the active layer from these gases. Since light, flexible and portable OLEDs are being employed in more diverse climates and environmental conditions, the OLED encapsulation layer must retain robust mechanical properties and stability in high temperature/high humidity conditions. Al2O3 films have demonstrated excellent barrier performance, but they readily hydrolyze when exposed to prolonged harsh environments. In this study, we fabricated a thin film encapsulation (TFE) film that was resistant to hydrolysis, using Al2O3/MgO (AM) nanolaminates. MgO has superior resistance to harsh environments, and the aluminate phase generated by the chemical reaction of Al2O3 and MgO provided excellent barrier performance, even after storage in harsh conditions. A multi-barrier fabricated using the AM nanolaminate showed excellent barrier performance, close to the level required by OLEDs. It did not significantly deteriorate even after a bending test of 1,000 iterations at 0.63% strain. After 1,000 cycle of bending, the electrical properties of the passivated OLEDs were not significantly degraded at shelf-lifetime test where the fabricated device was stored for 50 days in a harsh environment of 60℃, 90% relative humidity. The multi-barrier shows the best performance compared to previous studies on flexible encapsulation that can be used in harsh environments.

关键词： thin film encapsulation nanolaminate structure Al2O3 MgO flexible organic light emitting diode(OLED)

Effects of Polymeric Stabilizers on the Synthesis of Gold Nanoparticles

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Journal of Materials Science & Technology 2014年第2期30卷 107-111页

作者： eun Jung Kim jeong Hyun Yeum Jin Hyun choi Department of Advanced Organic Materials Science and Engineering Kyungpook National University Department of Bio-fibers and materials Science Kyungpook National University

Gold nanoparticles （AuNPs） stabilized with sodium alginate （SA）, glycol chitosan （GC）, polyvinyl alcohol （PVA）, and polyethyleneimine （PEI） were synthesized in aqueous solutions at room temperature. Different sizes and size distributions of AuNPs were obtained according to the polymeric stabilizers. The mean particle diameters of AuNPs synthesized with GC and PVA as stabilizers were about 5.1 and 5.3 nm, respectively, while those of AuNPs stabilized with SA and PEI were 8.4 and 10.8 nm, respectively. When SA was used, relatively large particles aggregated to form large clusters. In the case of GC, a number of small particles built up large clusters. When PVA was used, the size and the number of nanoperticles were estimated small with a low weight content of Au. For this reason, the PVA-stabilized AuNPs formed clusters with a small hydrodynamic size. The AuNPs synthesized in the aqueous solution of PEI without a reducing agent, sodium borohydride, were uniform in size and formed the smallest nanoclusters （67.4 nm）. In this case, the highest Au content was obtained. Sufficiently grown nanoparticles with a high Au content and a limited hydrodynamic size are considered to be suitable for a variety of applications.

关键词： Gold nanoparticles Sodium alginate Glycol chitosan Polyvinyl alcohol Polyethyleneimine