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G-StarRAW总部

城市环境设计 2014年第6期83卷 114-121页

作者： Katrien van Dijk Michel van de Kar Tjeerd van de Sandt Saskia Simon Mario Rodriguez Marina Cogliani jung-Won yoon Saskia Simon Marlies Boterman Marina Coglianiv Karolina Czeczek Green van Gogh Sarah Moylan Mafalda Rangel Tjeerd van de Sandt Richard Hollington Ⅲ Tjeerd van de Sandt Fred Awty Philippe Braun Kaveh Dabiri Katrien van Dijk Hans Hammink Mariano Sagasta Koen Stockbroekx

G-Star RAW新总部位于阿姆斯特丹Zuid-Oost工业区内的A10路旁,其单栋建筑集G-Star RAW各类不同设施于一身,旨在刺激各部门间的互动合作。横向的总部大楼长140m,面积达27 500m2,由一个容纳G-Star RAW各个核心部门的"创作核"组成,外围则... 详细信息

G-Star RAW新总部位于阿姆斯特丹Zuid-Oost工业区内的A10路旁,其单栋建筑集G-Star RAW各类不同设施于一身,旨在刺激各部门间的互动合作。横向的总部大楼长140m,面积达27 500m2,由一个容纳G-Star RAW各个核心部门的"创作核"组成,外围则是办公室、停车位和配套设施。对比强烈的材料突显出核心创作区和外环支援活动之间的区别──外环是体量庞大的黑色

关键词： Star G-StarRAW

动态超声检查冈上肌腱肩峰下滑行受限可预测肩关节腔容积减小和MR关节成像表现

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国际医学放射学杂志 2013年第1期 84-85页

作者： I.Kim J.H.Yi J.Lee J.H.Bae J.K.Lim J.P.yoon 岳建兰 Department of Radiology Kyungpook National University Hospital700-721200 Dongduk-RoJung-GuDaeguRepublic of Korea

目的本前瞻性研究的目的是通过比较疼痛性冈上肌腱肩峰下滑行受限(SGLS)的动态超声检查、MR关节成像表现和关节腔内最大注射容积来预测肩关节腔容积的减小。方法从2003年1月—2011年8月期间,67例病人分别接受了包括动态成像在内的超声... 详细信息

目的本前瞻性研究的目的是通过比较疼痛性冈上肌腱肩峰下滑行受限(SGLS)的动态超声检查、MR关节成像表现和关节腔内最大注射容积来预测肩关节腔容积的减小。方法从2003年1月—2011年8月期间,67例病人分别接受了包括动态成像在内的超声检查和MR关节成像检查。在MR关节成像检查之前,首先进行超声检查和超声引导的对比剂注射,比较每例SGLS病人的动态超声与所注射对比剂的体积,用于判断关节腔的最大容积和MR关节成像表现。结果动态超声检查结果显示,47例(70.1%)为SGLS阳性,20例(29.9%)为SGLS阴性。SGLS和注射体积之间的Pearson相关系数为-0.764(P<0.001)。SGLS和MR关节成像表现之间的Pearson相关系数为0.711(P<0.001)。SGLS阳性组的平均注射体积(22.0mL)和SGLS阴性组的平均注射体积(10.7mL)差异具有统计学意义(P<0.001)。结论 SGLS的超声成像与MR关节成像表现和关节腔的最大注射体积之间具有很好的相关性。这些表现可预测肩关节腔的容积减小,而后者是粘连性关节囊炎的重要特征,也提高了动态超声的应用价值。

关键词：动态超声检查关节腔关节间隙 MR 容积冈上肌腱肩峰肩胛骨受限

膝关节不全脱位的3 T MRI诊断:三维各向同性质子加权序列与二维序列的对比

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国际医学放射学杂志 2010年第1期 83-83页

作者： J.Y.jung Y.C.yoon J.W.Kwon J.H.Ahn B.K.Choe 李志明 Department of Radiology Samsung Medical CenterSchool of MedicineSungkyunkwan University

目的比较3.0T MR的三维各向同性快速自旋回波质子加权MRI对比二维快速自旋回波MRI在诊断膝关节不全脱位中的价值。材料与方法这项符合HIPAA要求的研究获得伦理审查委员会的批准,免除知情同意的要求。回顾性复习来自85例病人的87个膝关节... 详细信息

目的比较3.0T MR的三维各向同性快速自旋回波质子加权MRI对比二维快速自旋回波MRI在诊断膝关节不全脱位中的价值。材料与方法这项符合HIPAA要求的研究获得伦理审查委员会的批准,免除知情同意的要求。回顾性复习来自85例病人的87个膝关节MRI资料,所有病人同时接受三维各向同性序列和二

关键词： T MRI 膝关节二维序列不全脱位半脱位质子核子

聚醚醚酮制作可摘义齿人工牙耐磨性及硬度的研究

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口腔颌面修复学杂志 2018年第4期19卷 236-240页

作者：金智文韩建民刘云松尹祯敏孙玉春叶红强周永胜北京大学口腔医学院·口腔医院修复科国家口腔疾病临床医学研究中心口腔数字化医疗技术和材料国家工程实验室口腔数字医学北京市重点实验室北京100081 北京大学口腔医学院·口腔医院口腔材料研究室国家口腔疾病临床医学研究中心口腔数字化医疗技术和材料国家工程实验室口腔数字医学北京市重点实验室北京100081 北京大学口腔医学院·口腔医院口腔医学数字化中心卫生计生委口腔医学计算机应用工程技术研究中心国家口腔疾病临床医学研究中心口腔数字化医疗技术和材料国家工程实验室口腔数字医学北京市重点实验室北京100081

目的:比较聚醚醚酮制作的可摘义齿人工牙与两种临床常用的可摘义齿树脂人工牙的耐磨性及硬度。方法:用聚醚醚酮制作可摘义齿人工牙(A组),以普通合成树脂牙(拜耳牙,B组)和复合树脂牙(Endura塑钢牙,C组)为对照进行二体磨耗实验和硬度测试... 详细信息

目的:比较聚醚醚酮制作的可摘义齿人工牙与两种临床常用的可摘义齿树脂人工牙的耐磨性及硬度。方法:用聚醚醚酮制作可摘义齿人工牙(A组),以普通合成树脂牙(拜耳牙,B组)和复合树脂牙(Endura塑钢牙,C组)为对照进行二体磨耗实验和硬度测试。用TCML-II咀嚼模拟疲劳试验机进行磨耗实验,以滑石瓷为对磨物,加载力50N,循环加载30万次,并经5℃/55℃冷热水循环。用口内扫描仪扫描磨耗前后的人工牙形态,计算磨耗前后的体积变化,并用扫描电镜观察其磨耗表面。用显微硬度仪测量人工牙的维氏硬度。结果:三种树脂牙磨耗量分别为A组0.90±0.33 mm^3、B组2.42±0.99 mm^3、C组4.23±1.33 mm^3,三者之间有显著性差异(P<0.05)。三种树脂牙的硬度分别为A组29.16±2.58 Hv1/15、B组26.89±1.96 Hv1/15、C组35.24±1.90H v1/15,三者之间显著性差异(P<0.05)。结论:相比于普通合成树脂牙和复合树脂牙,PEEK树脂牙具有适中的硬度和良好的耐磨性。

关键词：聚醚醚酮人工牙耐磨性硬度

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Phase Ⅱ study of R-CVP followed by rituximab maintenance therapy for patients with advanced marginal zone lymphoma:consortium for improving survival of lymphoma(CISL)study

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Cancer Communications 2019年第1期39卷 526-535页

作者： Sung Yong Oh Won Seog Kim Jin Seok Kim Seok Jin Kim Dok Hyun yoon Deok-Hwan Yang Won Sik Lee Hyo jung Kim Ho-Young Yhim Seong Hyun Jeong Jong Ho Won Suee Lee Jee Hyun Kong Sung-Nam Lim Jun Ho Ji Kyung A.Kwon Gyeong-Won Lee Jae Hoon Lee Ho Sup Lee Ho-Jin Shin Cheolwon Suh Department of Internal Medicine Dong-A University HospitalBusan 49201Republic of Korea Department of Medicine Samsung Medical CenterSungkyunkwan University School of MedicineSeoul 06351Republic of Korea Division of Hematology Department of Internal MedicineYonsei University College of MedicineSeoul 03722Republic of Korea Department of Oncology Asan Medical CenterUniversity of Ulsan College of MedicineSongpa-guSeoul 05505Republic of Korea Department of Hematology-Oncology Chonnam National University Hwasun HospitalHwasun 58128Republic of Korea Department of Hematology Busan Paik HospitalInje University College of MedicineBusan 04511Republic of Korea Department of Internal Medicine Hallym University Sacred Heart HospitalHallym University College of MedicineAnyang 14068Republic of Korea Department of Internal Medicine Chonbuk National University HospitalJeonju 54907Republic of Korea Department of Hematology-Oncology Ajou University School of MedicineSuwon 16499Republic of Korea Department of Internal Medicine Soonchunhyang University Seoul HospitalSoonchunhyang University College of MedicineSeoul 04401Republic of Korea Division of Hematology-Oncology Department of Internal MedicineWonju Severance Christian HospitalYonsei University College of MedicineWonju 26426Republic of Korea Department of Internal Medicine Haeundae Paik HospitalInje University College of MedicineBusan 48108Republic of Korea Division of Hematology and Oncology Department of Internal MedicineSamsung Changwon HospitalSungkyunkwan University School of MedicineChangwon 51353Republic of Korea Division of Hematology-Oncology Department of Internal MedicineDongnam Institute of Radiological and Medical SciencesBusan 46033Republic of Korea Division of Hematology-Oncology Department of Internal MedicineGyeongsang National University HospitalGyeongsang National University College of MedicineJinju 52727Republic of Korea Department of Internal Medicine Gachon University Gil Medical CenterIncheon 21565Republic of

Background:The response rate and survival improvement for rituximab,a CD20-targeting monoclonal antibody,have been demonstrated in marginal zone lymphoma(MZL)as monotherapy and in combination with chemotherapeutic regimens,yet relapses still occur despite treatment ***,extending the period of remission in MZL patients remains an essential *** multicenter,single-arm,open-label phase II study evaluated the survival efficacy of 2 years of rituximab-maintenance therapy in patients with stage III-IV CD20-positive MZL who had responded to first-line R-CVP(rituximab,cyclophosphamide,vincristine,and prednisolone).The objective of this study was to determine whether rituximab maintenance following R-CVP warrants further ***:Prior to rituximab-maintenance therapy,patients received 6-8 cycles of first-line R-CVP therapy for stage III-IV ***(375 mg/m^(2)),cyclophosphamide(750 mg/m^(2)),and vincristine(1.4 mg/m^(2);maximum 2 mg)were administered via an intravenous infusion on day 1 of each 3-week cycle,while oral prednisolone(100 mg)was given on days 1-5 of each 3-week *** patients who achieved complete response(CR),partial response(PR),or stable disease(SD)to R-CVP treatment,were prescribed rituximab-maintenance therapy which was administered intravenously at a dose of 375 mg/m^(2) every 8 weeks for up to 12 *** primary endpoint was progression-free survival(PFS).Secondary endpoints were overall survival(OS)and treatment ***:47 patients were enrolled,of whom,45(96%)received rituximab-maintenance ***(33%)patients had nodal *** R-CVP first-line therapy,20(44%),22(49%),and 3(7%)patients achieved CR,PR,and SD,*** a median follow-up of 38.2 months,their observed 3-year PFS rate was 81%.During the rituximab-maintenance,6 PR and 1 SD patients achieved CR following the administration of *** LDH and the presence of B symptoms were found to be significant prognostic fac

关键词： Marginal zone Lymphoma Advanced stage Rituximab Cyclophosphamide Vincristine Maintenance Multicenter Open label Survival

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基于辣椒基因组测序探究辣味在种群中的进化

辣椒杂志 2014年第2期12卷 40-50页

作者： Seungill Kim Minkyu Park Seon-In Yeom Yong-Min Kim Je Min Lee Hyun-Ah Lee eunyoung Seo Jaeyoung Choi Kyeongchae Cheong Ki-Tae Kim Kyongyong jung Gir-Won Lee Sang-Keun Oh Chungyun Bae Saet-Byul Kim Hye-Young Lee Shin-Young Kim Myung-Shin Kim Byoung-Cheorl Kang Yeong Deuk Jo Hee-Bum Yang Hee-Jin Jeong Won-Hee Kang Jin-Kyung Kwon Chanseok Shin Jae Yun Lim June Hyun Park Jin Hoe Huh June-Sik Kim Byung-Dong Kim Oded Cohen Ilan Paran Mi Chung Suh Saet Buyl Lee Yeon-Ki Kim Younhee Shin Seung-Jae Noh Junhyung Park Young Sam Seo Suk-yoon Kwon Hyun A Kim Jeong Mee Park Hyun-Jin Kim Sang-Bong Choi Paul W Bosland Gregory Reeves Sung-Hwan Jo Bong-Woo Lee Hyung-Taeg Cho Hee-Seung Choi Min-Soo Lee Yeisoo Yu Yang Do Choi Beom-Seok Park Allen van Deynze Hamid Ashrafi Theresa Hill Woo Taek Kim Hyun-Sook Pai Hee Kyung Ahn Inhwa Yeam James J Giovannoni Jocelyn K C Rose Iben Sφrensen Sang-Jik Lee Ryan W Kim Ik-Young Choi Beom-Soon Choi Jong-Sung Lim Yong-Hwan Lee Doil Choi 刘峰张西露 Department of Plant Science Seoul National University Plant Genomics and Breeding Institute Seoul National University Department of Agricultural Biotechnology Seoul National University Department of Bioinformatics and Life Science Soongsil University Vegetable Breeding Research Center Seoul National University Agricultural Research Organization Institute of Plant Science Volcani Center Bet DaganIsrael. Agricultural Research Organization Institute of Plant Science Volcani Center Bet DaganIsrael Department of Bioenergy Science and Technology Chonnam National University Genomics Genetics Institute GreenGene BioTech Inc. Codes Division Insilicogen Inc. Ginseng Resources Research Laboratory Korea Ginseng Corporation Korea Research Institute of Bioscience and Biotechnology Division of Bioscience and Bioinformatics Myongji University Department of Plant and Environmental Sciences New Mexico State University Chile Pepper Institute New Mexico State University Seeders Inc. Department of Biological Sciences Seoul National University Arizona Genomics Institute University of Arizona Agricultural Genome Center National Academy of Agricultural Science Rural Development Administration Seed Biotechnology Center University of California Davis Davis California USA Department of Systems Biology Yonsei University Department of Horticulture and Breeding Andong National University US Department of Agriculture-Agricultural Research Service Robert W. Holley Center Ithaca New York USA Boyce Thompson Institute for Plant Research Cornell University Ithaca New York USA Department of Plant Biology Cornell University Ithaca New York USA Biotechnology Institute Nongwoo Bio Yeoju Korea Genome Center University of California Davis Davis California USA National Instrumentation Center for Environmental Management Seoul National University Seoul Korea 湖南省蔬菜研究所

辣椒(Capsicum annuum)是美洲最古老的驯化作物之一,在全世界被广泛种植。本研究对CM334(墨西哥地方品种)进行了全基因组测序和组装(覆盖度为186.6×),同时还对另外两个栽培种和一个野生种分别进行了重测序和从头(de novo)测序。结果表... 详细信息

辣椒(Capsicum annuum)是美洲最古老的驯化作物之一,在全世界被广泛种植。本研究对CM334(墨西哥地方品种)进行了全基因组测序和组装(覆盖度为186.6×),同时还对另外两个栽培种和一个野生种分别进行了重测序和从头(de novo)测序。结果表明辣椒基因组大小约为番茄的4倍,辣椒基因组上存在大量gypsy转座子和花椰菜病毒家族元件的积累。结合转录组综合分析认为,辣椒素合成酶基因表达模式的改变及新功能化是导致辣椒素生物合成的原因,研究还发现辣椒与番茄在乙烯合成及果实成熟调控方面存在明显不同的分子模式。辣椒参考基因组的发布为辣椒营养品质和药用价值的改善提供了重要平台。

关键词：基因组测序辣椒素参考基因 Capsicum 转座子辣椒果实分子模式生物合成基因表达模式基因组大小

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