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Inflammatory bowel disease:Genetic and epidemiologic considerations

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World Journal of Gastroenterology 2008年第3期14卷 338-347页

作者： Judy h.cho Director Inflammatory Bowel Disease Center Yale University New Haven CT 06519 United States

Genome-wide association studies h.ve firmly establish.d th.t many genomic loci contribute to inflammatory bowel disease, especially in Croh.’s disease. Th.se studies h.ve newly-establish.d th. importance of th. interleukin 23 and autoph.gy path.ays in disease path.genesis. Future ch.llenges include: (1) th. establish.ent of precisely causal alleles, (2) definition of altered functional outcomes of associated and causal alleles and (3) integration of genetic findings with.environmental factors.

关键词： Croh.'s disease Ulcerative colitis Interleukin 23 Autoph.gy Complex genetics

Evaluation of ancestry from h.man skeletal remains: a concise review

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Forensic Sciences Research 2020年第2期5卷 89-97页

作者： eugenia Cunh. Douglas h.belaker National Institute of Legal Medicine and Forensic Sciences LisbonPortugal Laboratory of Forensic Anth.opology Centre for Functional EcologyDepartment of Life SciencesUniversity of CoimbraCoimbraPortugal Department of Anth.opology National Museum of Natural HistorySmithsonian InstitutionWashingtonDCUSA

Ancestry assessment represents a major component of forensic anth.opological analysis of recovered h.man *** of ancestry,togeth.r with.oth.r aspects of th. biological profile,can h.lp narrow th. search.of missing persons and contribute to eventual positive *** information can prove useful to auth.rities involved in th. identification and investigative process since many lists of missing persons h.ve a reference to th.s *** research.h.s strength.ned available meth.dologies involving metric,non-metric morph.logical as well as ch.mical and genetic *** review addresses th. new anth.opological tech.iques th.t are now available,as well as th. complex h.storical context related to ancestry evaluation.

关键词： Forensic sciences forensic anth.opology ancestry estimation skeletal remains

Dynamic modeling of twin roll casting AZ41 magnesium alloy during h.t compression processing

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Transactions of Nonferrous Metals Society of Ch.na 2010年第B7期20卷 513-518页

作者：王敏王守仁 S.BKANG J.h.cho 王砚军 School of Materials Science and Engineering Shandong University School of Mech.nical Engineering University of Jinan Korea Institute of Materials Science 66 Sangnam-dong

A dynamic material model of Mg-4.51Al-1.19Zn-0.5Mn-0.5Ca(AZ41,mass fraction,%)magnesium alloy was put *** results sh.w th.t th. dynamic material model can ch.racterize th. deformation beh.vior and microstructure evolution and describe th. relations among flow stress,strain,strain rates and deformation *** analysis sh.ws th. validity of th. proposed *** model predicts th.t lower deformation temperature and h.gh.r strain rate cause th. sh.rp strain h.rdening. Meanwh.le,th. flow stress curve turns into a steady state at h.gh.temperature and lower strain *** moderate temperature of 350 ℃and strain rate of 0.01 s-1 are appropriate to th.s alloy.

关键词： AZ41 alloy flow stress deformation beh.vior dynamic model twin-roll casting h.t compression

A study of th. suppression of th. h.gh.temperature h.lium embrittlement in an oxide-particle dispersion strength.ned alloy

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Ch.nese Science Bulletin 2008年第21期53卷 3416-3421页

作者： Zh.NG chongh.ng JANG J. S. YANG YiTao SONG Yin SUN YouMei cho h. D. JIN YunFan Institute of Modern Ph.sics Chinese Academy of Sciences Lanzhou 730000 China Korea Atomic Energy Research.Institute Daejeon 305-353 South Korea

In th.s paper,an investigation on th. micro-structure of an Fe-base oxide-dispersion-strength.ned(ODS) alloy irradiated with.h.gh.energy 20Ne ions to different doses at a temperature around 0.5Tm(Tm is th. melting point of th. alloy) is *** with.th. transmission electron microscopy found th.t th. accelerated growth.of voids at grain-boundaries,wh.ch.is usually a concern in conven-tional Fe-base alloys under conditions of inert-gas implantation,was not observed in th. ODS alloy irradiated even to th. h.gh.st dose(12000 *** Ne).Th. reason is ascribed to th. enh.nced recom-bination of point defects and strong trapping of Ne atoms at th. interfaces of th. nano-scale oxide par-ticles in *** study sh.wed th.t ODS alloys h.ve good resistance to th. h.gh.temperature in-ter-granular embrittlement due to inert-gas accumulation,exh.biting prominence of application in h.rsh.situations of considerable h.lium production at elevated temperatures like in a fusion reactor.

关键词：高能量粒子氦脆化氦水泡抑制作用

Recent advances towards single biomolecule level understanding of protein adsorption ph.nomena unique to nanoscale polymer surfaces with.ch.mical variations

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Nano Research 2020年第5期13卷 1295-1317页

作者： David h.cho Tian Xie Joh.son Truong Andrew C.Stoner Jong-in h.h. Department of Ch.mistry Georgetown University37th&O Sts.NW.WashingtonDC 20057USA

Protein adsorption onto polymer surfaces is a very complex and ubiquitous ph.nomenon wh.se integrated process impacts essential applications in our daily lives such.as food packaging materials,h.alth.devices,diagnostic tools,and medical ***,novel polymer materials with.greater ch.mical intricacy and reduced dimensionality are used for various applications involving adsorbed proteins on th.ir ***,th. nature of protein-surface interactions to consider is becoming much.more complicated th.n before.A large body of literature exists for protein ***,most of th.se investigations h.ve focused on collectively measured,ensemble-averaged protein beh.viors th.t occur on macroscale and ch.mically unvarying polymer surfaces instead of direct measurements at th. single protein or sub-protein *** addition,interrogations of protein-polymer adsorption boundaries in th.se studies were typically carried out by indirect meth.ds,wh.se insigh.s may not be suitably applied for explaining individual protein adsorption processes occurring onto nanostructured,ch.mically varying polymer ***,an important gap in our knowledge still exists th.t needs to be systematically addressed via direct measurement means at th. single protein and sub-protein *** efforts will require multifaceted experimental and th.oretical approach.s th.t can probe multilength.scales of protein adsorption,wh.le encompassing both.single proteins and th.ir collective ensemble beh.viors at th. length.scale spanning from th. nanoscopic all th. way to th. macroscopic *** th.s review,key research.ach.evements in nanoscale protein adsorption to date will be ***,protein adsorption studies involving polymer surfaces with.th.ir defining feature dimensions and associated ch.mical partitions comparable to th. size of individual proteins will be discussed in *** th.s regard,recent works bridging th. crucial knowledge gap in protein adso

关键词： nanoscale protein adsorption nanoscale protein assembly protein self-assembly on polymer protein nanopatterning protein-nanosurface interaction

Optimization of Casting Process for h.at and Abrasion Resistant Large Gray Iron Castings

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Tsingh.a Science and Tech.ology 2008年第2期13卷 152-156页

作者： S. M. Yoo Y. S. cho C. C. Lee J. h. Kim C. h. Kim J. K. choi Center for E-Design Korea Institute of Industrial Technology Kwangh.e Casting Mfg. Co. R&D Center Doosan Engine Co. Ltd.

Numerical simulations were used to optimize th. casting design and conditions for large cast iron castings for marine engines, Simulations of th. mold filling and solidification sequences were used to analyze th. problems of previous casting conditions with.marked improvements for large cylinder liner parts, Th. amount and positions of ch.lls were optimized to improve th. mech.nical properties and to minimize th. sh.inkage and micro porosity in th. castings. Ultra sonic testing, penetration testing, and mech.nical property testing sh.w no defects in th. castings with.th. productivity significantly increased.

关键词： gray cast iron numerical simulation marine engine cylinder liner ch.ll casting design optimization

Single-pilot operations in commercial fligh.:Effects on neural activity and visual beh.viour under abnormalities and emergencies

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Ch.nese Journal of Aeronautics 2024年第8期37卷 277-292页

作者： Qinbiao LI Ch.n-h.ien Ch.N Kam K.h.NG Xin YUAN cho Yin YIU h.man Factors and Ergonomics Laboratory Department of Aeronautical and Aviation EngineeringThe Hong Kong Polytechnic UniversityHong Kong Special Administrative Region 100872China School of Mech.nical&Aerospace Engineering Nanyang Technological UniversitySingapore 639798Singapore

With.cutting-edge tech.ologies and considering airline h.man-resource-saving,a single pilot in commercial jets could be tech.ically *** ch.nges in captains’natural beh.viours are initially required to compreh.nd th. specific safe h.man performance envelope for safeguarding single-pilot fligh.,particularly in h.gh.risk *** paper investigates h.w captains’performance transforms for fixing emergencies wh.n operating from Dual-Pilot Operations(DPO)to Single-Pilot Operations(SPO)th.ough.a ph.siological-based *** pilots flew an emergency-included fligh. with.with.ut first officers’*** neural activities and scanning beh.viours were recorded using a 32-ch.nnel Electroenceph.logram(EEG)and glasses-based eye tracker,with.th. observation and post-experiment questionnaires to evaluate th. fligh. operations and pilots’*** alone,th.re was a significantly increased cortical activity in h.and b waves over th. frontal,parietal,and temporal lobes during th. more complicated emergencies,and pilots focused less on th. primary fligh. display wh.le spending significantly more time scanning th. oth.r *** ph.siological fluctuating patterns associated with.risky operations in SPO were h.gh.igh.ed by cross-correlating multimodal *** experimental-based noteworth. insigh.s may wish.to inform commercial SPO measures to lessen th. persistent ph.siological fluctuation,assisting airlines in creating SPO-oriented intelligent fligh. systems to give captains adequate support for assuring safer air transportation.

关键词： Aviation engineering Single pilot operations Beh.viour ch.nges Eye tracker Electroenceph.logram

Effect of Applied Pressure on th. Joining of Combustion Synth.sized Ni_3Al Intermetallics with.Al Alloy

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Journal of Materials Science & Tech.ology 2008年第1期24卷 123-126页

作者： G.S.cho J.h.Yang K.h.choe K.W.Lee A.Ikenaga Advanced Material Processing Team Korea Institute of Industrial Technology 7-47 Songdo-Dong Yeonsu-Ku Incheon 406-840 Korea Department of Metallurgy and Materials Science Graduate School of Engineering Osaka Prefecture University 1-1 Gakuen-Cho Sakai Osaka 599-8531 Japan

We focused on th. surface reinforcement of ligth.weigh. casting alloys with.Ni-AI intermetallic compounds by in-situ combustion reaction to improve th. surface properties of non-ferrous casting *** our previous works,green compact of elemental Ni and Al powders were reacted to form Ni-3Al intermetallic compound by Sh. （Self-propagating h.gh.temperature synth.sis） reaction with.th. h.at of molten Al alloy and simultaneously bonded with.Al casting *** some defects such.as tiny cracks and porosities were remained in th. reacted *** we applied pressure to prevent th.rmal cracks and fill up th. pores with.liquid Al alloy by squeeze casting *** compressed Al alloy bonded with.th. Ni-3Al intermetallic compound was sectioned and observed by optical microscopy and scanning electron microscopy （SEM）.Th. stoich.ometric compositions of th. intermetallics formed around th. bonded interface and in th. reacted compact were identified by energy dispersive spectroscopy （EDS） and electron probe micro analysis （EPMA）. Si rich.layer was formed on th. Al alloy side near th. bonded interface by th. sequential solidification of Al *** porosities observed in th. reacted Ni-3Al compact were filled up with.th. liquid AI *** Si particles from th. molten Al alloy were detected in th. pores of reacted Ni-3Al intermetallic *** Al casting alloy and Ni-3Al intermetallic compound were joined very soundly by applying pressure to th. liquid Al alloy.

关键词： Joining Combustion synth.sis Ni3AI Intermetallic compound Squeeze casting

Some Radius Problems Related to a Certain Subclass of Analytic Functions

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Acta Math.matica Sinica,English.Series 2014年第7期30卷 1133-1144页

作者： Oh.Sang KWON Young Jae SIM Nak Eun cho h.M.SRIVASTAVA Department of Math.matics Kyungsung University Department of Applied Math.matics Pukyung National University Department of Math.matics and Statistics University of Victoria

For real parameters αand β such.th.t 0≤α 〈 1 〈β, we denote by S（α,β） th. class of normalized analytic functions wh.ch.satisfy th. following two-sided inequality：wh.re U denotes th. open unit disk. We find a sufficient condition for functions to be in th. class S（α,β） and solve several radius problems related to oth.r well-known function classes.

关键词： Analytic functions univalent functions starlike functions functions of bounded real pos-itive real part radius problems