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Effects of a sex ratio gradient on female mate-copying and choosiness in Drosophila melanogaster

Current Zoology 2018年第2期64卷 251-258页

作者： Magdalena MONIER Sabine NOBEL Guillaume ISABEL etienne danchin UMR-5174 Laboratoire Evolution & Diversite Biologique (EDB) Centre National de la Recherche Scientifique (CNRS) Institut de Recherche pour le Developpement (IRD) Universite de Toulouse 118 route de NarbonneF-31062 Toulouse Cedex 9 France Centre de Recherches sur la Cognition Animale (CRCA) Centre de Biologie Integrative (CBI) Centre National de la Recherche Scientifique (CNRS) Universite de Toulouse 118 route de Narbonne F-31082 Toulouse Cedex 9 France

In many sexually reproducing species, individuals can gather information about potential mates by observing their mating success. This behavioral pattern, that we call mate-copying, was reported in the fruit fly Drosophila rnelanogaster where females choosing between 2 males of contrasting phenotypes can build a preference for males of the phenotype they previously saw being chosen by a demonstrator female. As sex ratio is known to affect mate choice, our goal was to test whether mate-copying is also affected by encountered sex ratios. Thus, we created a gradient of sex ratio during demonstrations of mate-copying experiments by changing the number of females observ- ing from a central arena 6 simultaneous demonstrations unfolding in 6 peripheral compartments of a hexagonal device. We also tested whether the sex ratio experienced by females during demon- strations affected their choosiness （male courtship duration and double courtship rate） in subse- quent mate-choice tests. Experimental male：female sex ratio during demonstrations did not affect mate-copying indices, but positively affected the proportion of both males courting the female during mate-choice tests, as well as male courtship duration, the latter potentially explaining the for- mer relationship. As expected, the sex ratio affected female choosiness positively, and Drosophila females seem to have evolved a mate-copying ability independently of sex ratio, and a capacity to adapt their choosiness to male availability. This suggests that, as in many animal species, individuals, especially females, can adapt their mate choice depending on the current sex ratio.

关键词： competition Drosophila melanogaster experimental protocol mate-copying social learning sex ratio.

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A survey on Fourier analysis methods for solving the compressible Navier-Stokes equations Dedicated to the NSFC-CNRS Chinese-French summer institute on fluid mechanics in 2010

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Science China Mathematics 2012年第2期55卷 245-275页

作者： danchin Raphaeel LAMA UMR 8050 Universitg Paris-Est 61 avenue du Gdn@al de Gaulle 94010 Crdteil Cedex France

Fourier analysis methods and in particular techniques based on Littlewood-Paley decomposition and paraproduct have known a growing interest recently for the study of nonlinear evolutionary equations. In this survey paper, we explain how these methods may be implemented so as to study the compresible Navier-Stokes equations in the whole space. We shall investigate both the initial value problem in critical Besov spaces and the low Mach number asymptotics.

关键词： compressible fluids critical regularity Besov spaces Fourier analysis Mach number

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Cost-effectiveness modelling of percutaneous coronary interventions in stable coronary artery disease

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World Journal of Cardiology 2015年第10期7卷 594-602页

作者： Ariel Beresniak Thibaut Caruba Brigitte Sabatier Yves Juillière Olivier Dubourg Nicolas danchin Data Mining International Research and Development Paris-Descartes University Department of Pharmacy Hopital Européen Georges Pompidou Department of Cardiology Institut Lorrain du Coeur et des Vaisseaux Department of Cardiology Hopital Ambroise Paré UFR des Sciences de la Santé Simone Veil Université Versailles Saint Quentin en Yvelines Division of Coronary Artery Disease and Intensive Cardiac Care Hopital Européen Georges Pompidou

The objective of this study is to develop a cost-effectiveness model comparing drug eluting stents(DES) vs bare metal stent(BMS) in patients suffering of stable coronary artery disease. Using a 2-years time horizon, two simulation models have been developed: BMS first line strategy and DES first line strategy. Direct medical costs were estimated considering ambulatory and hospital costs. The effectiveness endpoint was defined as treatment success, which is the absence of major adverse cardiac events. Probabilistic sensitivity analyses were carried out using 10000 Monte-Carlo simulations. DES appeared slightly more efficacious over 2 years(60% of success) when compared to BMS(58% of success). Total costs over 2 years were estimated at 9303 € for the DES and at 8926 € for bare metal stent. Hence, corresponding mean cost-effectiveness ratios showed slightly lower costs(P < 0.05) per success for the BMS strategy(15520 €/success), as compared to the DES strategy(15588 €/success). Incremental costeffectiveness ratio is 18850 € for one additional percent of success. The sequential strategy including BMS as the first option appears to be slightly less efficacious but more cost-effective compared to the strategy including DES as first option. Future modelling approaches should confirm these results as further comparative data in stable coronary artery disease and long-term evidence become available.

关键词： Cost-effectiveness Percutaneous coronary Coronary artery disease Drug eluting stent

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Bilateral vs unilateral internal mammary revascularization in patients with left ventricular dysfunction

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World Journal of Cardiology 2017年第4期9卷 339-346页

作者： Batric Popovic Pablo Maureira Yves Juilliere Nicolas danchin Damien Voilliot Fabrice Vanhuyse Jean Pierre Villemot Département de Cardiologie CHU Nancy Service de Chirurgie des Maladies Cardiovasculaires et TransplantationsCHU Nancy Hopital Européen Georges Pompidou Assistance Publique des Hopitaux de Paris(AP-HP)UniversitéParis Descartes

AIM To investigate the survival benefit of bilateral internal mammary artery(BIMA) grafts in patients with left ventricular *** Between 1996 and 2009,we performed elective,isolated,primary,multiple cardiac arterial bypass grafting in 430 consecutive patients with left ventricular ejection fraction ≤ 40%. The early and long-term results were compared between 167 patients undergoing BIMA grafting and 263 patients using left internal mammary artery(LIMA)-saphenous venous grafting(SVG).RESULTS The mean age of the overall population was 60.1 ± 15 years. In-hospital mortality was not different between the two groups(7.8% vs 10.3%,P = 0.49). Early postoperative morbidity included myocardial infarction(4.2% vs 3.8%,P = 0.80),stroke(1.2% vs 3.8%,P = 0.14),and mediastinitis(5.3% vs 2.3%,P = 0.11). At 8-year follow-up,Kaplan-Meier-estimated survival(74.2% vs 58.9%,P = 0.02) and Kaplan-Meier-estimated event-free survival(all cause deaths,myocardial infarction,stroke,target vessel revascularization,heart failure)(61.7% and 41.1%,P < 0.01) were significantly higher in the BIMA group compared with the LIMA-SVG group in univariate analysis. The propensity score matching analysis confirmed that BIMA grafting is a safe revascularization procedure but there was no long term survival(P = 0.40) and event-free survival(P = 0.13) in comparison with LIMA-SVG *** Our longitudinal analysis suggests that BIMA grafting can be performed with acceptable perioperative mortality in patients with left ventricular dysfunction.

关键词： Bilateral internal mammary artery grafting Heart failure Coronary artery disease

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原生艺术在亚洲

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上海艺术家 2015年第5期 44-46页

作者：罗亨曲晓蕊

原生艺术是原始的、无经验基础的艺术创作方式,在强烈的个人需要和不可抑制的灵感推动下去描、去画、去雕刻和组装。在原生艺术中,艺术创作的过程本身比艺术更为重要。

关键词：个人需要创作方式埃尔策展人布菲超现实主义边缘地位洪通瑞士洛桑精神病人

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口腔健康和血压:法国预防和临床研究中心队列研究

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中华高血压杂志 2016年第3期24卷 298-298页

作者： Darnaud C Thomas F Pannier B danchin N Bouchard P 陈云叶鹏

慢性牙周病是由细菌引起的牙周组织炎症反应。炎症可能是发生高血压的病因，牙周病与心血管病的风险增加有关。该研究评估成年人群口腔健康状况与发生高血压风险的相关性。

关键词：口腔健康状况高血压队列研究临床研究慢性牙周病预防法国炎症反应

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慢性口服抗凝药物对急性心肌梗死患者治疗和预后的影响:RICO调查资料

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世界核心医学期刊文摘（心脏病学分册） 2006年第12期2卷 43-页

作者： Oudot A. Steg P.G. danchin N. Y. Cottin 朱冰坡 Service de Cardiologie CHUDijonBd de Lattre de Tassigny21034 Dijon Cedex France Dr.

Objective: To determine the prevalence of chronic oral anticoagulant drug treatment(COA) among patients with acute myocardial infarction(AMI) and its impact on management and outcome. Methods: All patients with ST segment elevation AMI on the RICO(a French regional survey for AMI) database were included in this analysis. COA was defined as continuous use ≥48 hours before AMI. Results: Among the 2112 patients with ST elevation myocardial infarction(STEMI), 93(4%) patients were receiving COA. These patients were older and more likely to have a history of hypertension, diabetes and prior myocardial infarction than patients without COA. In addition, fewer patients who received COA underwent reperfusion therapy or received an antiplatelet agent(aspirin/thienopyridines). Moreover, patients receiving COA experienced a higher incidence of in-hospital major adverse events(death, recurrent myocardial infarction or major bleeding, p=0.005). Multivariate analysis showed that only ejection fraction, current smoking and multiple vessel disease, but not COA, were independent predictive factors for major adverse events. In contrast, COA was an independent predictive factor for heart failure when adjusted for age, diabetes, creatinine clearance, reperfusion, heparin and glycoprotein Ⅱb/Ⅲa inhibitors(odds ratio 2.06, CI 95%1.23 to 3.43, p=0,005). Conclusion: In this population based registry, patients with STEMI with prior use of COA constituted a fairly large group(4%) with an overall higher baseline risk profile than that of patients without COA. Fewer in the COA group received reperfusion therapy or aggressive antithrombotic treatment and they experienced more adverse in-hospital outcomes. Thus, further studies are warranted to develop specific management strategies for this high risk group.

关键词：抗凝药物再灌注预测因素预后心肌梗死

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动脉间走行的冠状动脉异常病人CT血管成像的恶性解剖标准

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国际医学放射学杂志 2015年第3期 291-291页

作者： G.Ashrafpoor N.danchin L.Houyel R.Ramadan E.Belli J.F.Paul 钟垚莹 Department of Radiology Institut Mutualiste Montsouris42 Boulevard Jourdan75014 Paris France

目的尝试确定动脉间走行的冠状动脉异常(ACAIAC)病人主要不良心脏事件(MACE)和冠状动脉CT成像(CCTA)评估的解剖标准之间的关系。材料与方法从一

关键词：冠状动脉异常 MACE 病人 CCTA CT

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