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Bone Metastases Indicative of Post Viral Hepatitis C Hepatocarcinoma: About Two Observations

Open Journal of Rheumatology and Autoimmune Diseases 2021年第4期11卷 144-151页

作者： Prenam Houzou Sadat Oniankitan Omboma Bouglouga Bidamin N’Timon erika djougnwe mba Viwale Etonam Koffi-Tessio Kodjo Kakpovi Komi Cyrille Tagbor Eyram Fianyo Awaki-Esso Atake Owonayo Oniankitan Moustafa Mijiyawa Department of Rheumatology University Teaching Hospital of Kara Kara Togo Department of Gastroenterology and Hepatology University Teaching Hospital of Kara Kara Togo Department of Radiology University Teaching Hospital of Kara Kara Togo Department of Rheumatology University Teaching Hospital Sylvanus Olympio of Lomé Lomé Togo Department of Rheumatology Regional Hospital of Kara Tomdè Kara Togo Department of Rheumatology District Hospital of Bè Lomé Togo

Background: Hepatocarcinoma is the most common primary malignant tumor of the liver with rare bone metastases, electively residing in the vertebrae, ribs and sternum. They remain exceptionally revealing. Cases reports: We report two cases of bone metastases indicative of hepatocellular carcinoma in patients with viral hepatitis C. Through these two observations, we describe the various clinical, paraclinical and therapeutic aspects of this condition whose prognosis is poor. Conclusion: Although unusual, osteolytic bone metastases may be indicative of hepatocellular carcinoma, the diagnosis must be made in the event of any tumor bone involvement in a patient with chronic liver disease, particularly viral.

关键词： Bone Metastasis Hepatocarcinoma Viral Hepatitis Togo

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Profile of Infectious Spondylodiscitis in Rheumatology Consultation at University Teaching Hospital of Kara, Togo

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Open Journal of Rheumatology and Autoimmune Diseases 2021年第4期11卷 160-168页

作者： Prenam Houzou Awaki-Esso Atake Kodjo Kakpovi Viwale E. Koffi-Tessio Komi C. Tagbor Eyram Fianyo Sadat Oniankitan Mamadou L. Diallo Pahimi Yibe erika djougnwe mba Poyode Lokou Owonayo Oniankitan Moustafa Mijiyawa Department of Rheumatology University Teaching Hospital of Kara Kara Togo Department of Rheumatology Regional Hospital of Kara Tomdè Kara Togo Department of Rheumatology University Teaching Hospital Sylvanus Olympio Lomé Togo Department of Rheumatology District Hospital of Bè Lomé Togo

Objectives: The objective is to determine the frequency and the semiological and evolutionary profiles of infectious spondylodiscitis in hospital practice in Kara. Patients and methods: This was a cross-sectional study of a case series of patients with infectious spondylodiscitis, who were admitted to the rheumatology department of Kara University Hospital in North Togo. Results: Among the 3972 examined patients, 86 (33 males and 53 females) patients (2.16%) had infectious spondylodiscitis. The average age of these patients at the onset of the disease was 47.20 years. The average duration of the disease was 11.41 months. Tuberculosis was suspected in 77 of 86 patients (89.53%). The infectious spondylodiscitis most often affected the lumbar (51.04%) and dorsal (21.87%) segments and was associated with a pulmonary location in 31 patients (36.04%). In addition to underdevelopment and poor hygiene (72 cases), alcoholism (15 cases) and human immunodeficiency virus infection (10 cases) were the main risk factors identified. The progress with the medical treatment was favorable in 65 patients (75.58%) and 16 patients were lost to follow-up. Conclusion: The frequency of infectious spondylodiscitis reflects the underdevelopment and poor hygiene levels in Black Africa. Its etiology is most commonly associated with tuberculosis and remain

关键词： Infection Spondylodiscitis Tuberculosis Black Africa

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Infectious Spondylodiscitis in the Elderly in a Rheumatological Setting in Togo

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Open Journal of Rheumatology and Autoimmune Diseases 2022年第1期12卷 1-8页

作者： Kodjo Kakpovi Awaki-Esso Atake Prenam Houzou Issa Diallo Mamadou L. Diallo Viwale E. Koffi-Tessio Komi C. Tagbor Sadat Oniankitan Pahimi Yibe erika djougnwe mba Moubarak Tiadjeri Eyram Fianyo Owonayo Oniankitan Moustafa Mijiyawa Department of Rheumatology Regional Hospital of Kara Kara Togo Department of Rheumatology University Teaching Hospital of Kara Kara Togo Department of Rheumatology University Teaching Hospital Sylvanus Olympio Lomé Togo Department of Rheumatology District Hospital of Bè Lomé Togo

Infectious spondylodiscitis in the elderly is a diagnostic and therapeutic emergency. They are mainly a functional and sometimes vital prognosis issue, with long-term chronic disabling sequelae and significant social costs. Study aim: To describe the epidemiological, clinical, paraclinical, therapeutic and evolutionary aspects of infectious spondylodiscitis in the elderly in a rheumatological setting in Togo. Patients and methods: This was a multicenter, cross-sectional study conducted on the records of patients aged at least 65 years, suffering from infectious spondylodiscitis and hospitalized in four rheumatology units from their respective opening dates till December 31, 2020. Data collection lasted three months (December 1, 2020 to February 29, 2021). The diagnosis of infectious spondylodiscitis was radioclinical and laboratory-based. Results: 83 (49 women, 34 men) of the 1281 patients (6.48%) examined had infectious spondylodiscitis. The mean age at consultation was 70.59 ± 5.09 years, and the mean duration of the clinical course was 12 months. Spondylodiscitis was of tuberculous etiology (89.20%). It was most often found in the lumbar (56.62%) and dorsal (21.69%) segments. The location was multifocal in 12.05% of cases. It was associated with pulmonary involvement in 22.64% of cases. A neurological complication was identified in 48.19%. The main risk factors identified were promiscuity (48.82%), chronic alcoholism (18.07%), HIV infection (8.43%), diabetes (6.03%) and sickle cell disease (6.03%). The clinical course under medical treatment was favorable in 57 patients (68.68%). Conclusion: Infectious spondylodiscitis remains a frequent reason for hospitalization, tuberculosis being the most frequent etiology. Multifocal location, deterioration of general condition, gibbosity and neurological complications are exclusive to the elderly subject.

关键词： Infection Tuberculosis Spondylodiscitis Aging Sub-Saharan Africa

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Chronic Inflammatory Rheumatic Diseases in Rheumatological Practice in Lomé(Togo)

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Open Journal of Rheumatology and Autoimmune Diseases 2022年第1期12卷 9-20页

作者： Kodjo Kakpovi Sadat Oniankitan Komi C. Tagbor Koulouktsoa Kondian Viwalé ES Koffi-Tessio Awaki-Esso Atake Lamine Mamadou Diallo Pahimi Yibe erika djougnwe mba Moubarak Tiadjeri Eyram Fianyo Prénam Houzou Owonayo Oniankitan Moustafa Mijiyawa Rheumatology Department Regional Teaching Hospital of Kara Kara Togo Rheumatology Department University Teaching Hospital Sylvanus Olympio Lomé Togo Rheumatology Department Hospital of Be Lomé Togo Rheumatology Department University Teaching Hospital of Kara Kara Togo

Chronic inflammatory rheumatism is a pathology of variable frequency and severity with a significant impact on the socio-economic, personal and family level. Study Aim: To describe the epidemiological, clinical, laboratory, radiological, therapeutic and evolutive features of chronic inflammatory rheumatic diseases in rheumatological practice in Togo. Patients and Methods: This was a multicenter cross-sectional study conducted from January 2011 to December 2019 on patients examined in the three rheumatology departments in Lomé (Togo). Patients 18 years old and above who have presented joint pain with or without synovitis, and/or rachialgia (back pain) for at least three months were included. The diagnosis of chronic inflammatory rheumatic diseases was made according to international consensus criteria. Results: Out of the 20333 patients whose files were collected during our study period, 290 (1.43%) suffered from chronic inflammatory rheumatic diseases. There were 226 (77.93%) females and 64 (22.07%) males. The mean age of the patients was 42.79 ± 15.18 years. The mean duration of symptoms was 40.80 ± 54.09 months. Arthritis (67.24%) was the main reason for consultation, followed by joint pain (31.38%). rheumatoid arthritis (41.03%), unclassified chronic inflammatory rheumatic diseases (38.62%), spondyloarthropathies (15.17%) and systemic lupus erythematosus (2.41%) were the major clinical forms. The immunological tests performed in 13.79% of cases were positive in 52.94% of cases. Carpitis (57.55%) and diffuse osteoporosis (45.28%) were the commonest radiographic features of the hands. 289 patients (99.66%) received symptomatic treatments such as NSAIDs (73.36%) and corticosteroids (51.90%) and 90 patients (31.03%) were treated with synthetic DMARDs such as methotrexate (88.89%). The outcome was favorable in 27.93% of cases. Conclusion: Chronic inflammatory rheumatic diseases are common diseases in rheumatological practice in Togo that deserve special attention. The

关键词： Chronic Inflammatory Rheumatic Diseases Rheumatoid Arthritis Spondyloarthropathies Sub-Saharan Africa

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