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Neural Regeneration Research 2024年第7期19卷 1417-1418页

作者： Jonathan Witton erica S.Brady Michael T.Craig Department of Clinical and Biomedical Sciences Faculty of Health and Life SciencesUniversity of ExeterExeterEnglandUK Gladstone Institute for Neurological Disease San FranciscoCAUSA School of Psychology and Neuroscience College of MedicalVeterinary and Life SciencesUniversity of GlasgowGlasgowScotlandUK

Dementia is a devastating syndrome characterized by memory problems,confusion,and behavior changes that prevent people from performing everyday activities.It is the leading cause of dependency and disability amongst older people,resulting in a global economic cost of ~$1.3 trillion.Around 58 million people are currently afflicted by dementia worldwide,with Alzheimer s disease(AD) causing most(60-70%) of these cases.

关键词： Alzheimer everyday performing

Characteristics and trends of pediatric firepit burns: insights for prevention and safety

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World Journal of Pediatric Surgery 2024年第1期7卷 54-58页

作者： Maria Fazal Charbel Chidiac Raheel Ahmad Oussama Issa erica Hodgman Alejandro V Garcia Johns Hopkins School of Medicine BaltimoreMarylandUSA Department of Surgery Division of Pediatric SurgeryJohns Hopkins School of MedicineBaltimoreMarylandUSA Division of the Biological Sciences University of ChicagoChicagoIlinoisUSA School of Medicine American University of BeirutBeirutLebanon

Introduction As fire pits grow in popularity,so do the associated burn injuries.Our study examines pediatric fire pit burns characteristics to raise awareness and promote safety precautions.Methods We conducted a retrospective review of pediatric patients(<21 years)with firepit burns at a tertiary care hospital from 2016 to 2021.Results Eighty-four patients were identified,of whom 70.2%were male,with a median age of 62 months.The median percent total body surface area burned was 2%(interquartile range(IQR)=1-4).Thirty-five(41.7%)patients were admitted and 7(8.3%)underwent grafting.Neck and trunk burns had the highest grafting rates(66%and 33%,respectively).The hands(41.7%)and the lower extremities(27.4%)were the most frequently burned body areas.The leading causes of burns were ashes/hot coals(34.5%),flames(31.0%),and direct contact(25.0%),often resulting from falling into the fire(59.5%)or running or playing in activities near it(26.2%).Thirty-five(41.7%)were admitted for inpatient management,while 49(58.3%)were treated as outpatient.Eleven(13.2%)underwent at least one reconstructive surgery,7(8.4%)had at least one rehabilitation visit,and 65(77.4%)had follow-up clinic visits.The median length of stay was 2 days(IQR=1.0-3.5).The peak months for burns were from August through October(n=40,46.0%),with an increase observed from 10 cases in 2016to 20 cases in 2020.Conclusions Given the significant proportion of firepit burns resulting from unsafe fire behaviors,it is crucial that caretakers are aware of proper firepit safety precautions.Level ofevidence Il.

关键词： burns admitted prevention

Quick and easy assessment of sarcopenia in cirrhosis: Can ultrasound be the solution?

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World Journal of Gastroenterology 2024年第17期30卷 2287-2293页

作者： Francesca Campani Tancredi Vincenzo Li Cavoli Umberto Arena Fabio Marra erica Nicola Lynch Claudia Campani Department of Health Science University Hospital CareggiUniversity of FlorenceFlorence 50134Italy Internal Medicine and Liver Unit University Hospital CareggiUniversity of FlorenceFlorence 50134Italy Department of Experimental and Clinical Medicine University of FlorenceFlorence 50134Italy Gastroenterology Research Unit Department of Experimental and Clinical Biomedical Sciences“Mario Serio”University of FlorenceFlorence 50134Italy Department of Medical Biotechnologies University of SienaSiena 53100Italy

Cirrhosis is frequently associated with sarcopenia,with reported rates of over 80%in patients with decompensated alcohol-related liver disease.Sarcopenia nega-tively impacts the prognosis of cirrhotic patients and affects the response to treatment of patients with hepatocellular carcinoma(HCC).For these reasons,identifying an easy-to-perform method to assess sarcopenia in is a key element in the optimization of care in this patient population.Assessment of muscle mass by computed tomography is considered the standard of care for the diagnosis of sarcopenia,but exposure to radiation and high costs limit its application in this setting,especially for repeated assessments.We believe that ultrasound,a cheap and harmless technique also used for HCC screening in cirrhotic patients,could have an expanding role in the diagnosis and follow-up of sarcopenia in these patients.

关键词： Sarcopenia Ultrasound Cirrhosis Hepatocellular carcinoma Computed tomography

Effects of a school-based karate intervention on academic achievement,psychosocial functioning,and physical fitness:A multi-country cluster randomized controlled trial

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Journal of Sport and Health Science 2024年第1期13卷 90-98页

作者： Tania Pinto-Escalona erica Gobbi Pedro L.Valenzuela Simon J.Bennett Pierluigi Aschieri Manuel Martin-Loeches Antonio Paoli Oscar Martinez-de-Quel Faculty of Education Complutense University of MadridMadrid 28040Spain Department of Biomolecular Sciences University of Urbino“Carlo Bo”Urbino 61029Italy Department of Systems Biology University of AlcaláMadrid 28805Spain Research Institute for Sport and Exercise Sciences Faculty of ScienceLiverpool John Moores UniversityLiverpoolL33AFUK Italian Judo WrestlingKarate and Martial Arts FederationRome 00122Italy Psychobiology&Methods for the Behavioural Sciences Department Complutense University of MadridMadrid 28040Spain Department of Biomedical Sciences University of PaduaPadua 35122Italy

Purpose:To examine the effects of a school-based karate intervention on academic achievement,psychosocial functioning,and physical fitness in children aged 7-8 years.Methods:Twenty schools in 5 different European countries(2 second-grade classrooms per school)participated in a cluster randomized controlled trial(Sport at School trial).Participants were assigned to either a control group,which continued with their habitual physical education lessons,or to an intervention group,which replaced these lessons with a 1-year karate intervention(Karate Mind and Movement program).A total of 721 children(344 girls and 377 boys,7.4±0.5 years old,mean±SD)completed the study,of which 333 and 388 were assigned to the control group and intervention group,respectively.Outcomes included academic performance(average grade),psychosocial functioning(Strengths and Difficulties Questionnaire for parents),and different markers of physical fitness(cardiorespiratory fitness,balance,and flexibility).Results:The intervention provided small but significant benefits compared to the control group for academic achievement(d=0.16;p=0.003),conduct problems(d=-0.28;p=0.003),cardiorespiratory fitness(d=0.36;p0.05).Conclusion:A 1-year school-based karate intervention was effective in improving academic achievement,conduct problems,and physical fitness in primary school children.The results support the inclusion of karate during physical education lessons.

关键词： Academic performance Cardiorespiratory fitness Conduct problems Karate Physical fitness

Homocysteinemia and Depression in Community-Dwelling Older Adults: The Cohort Longitudinal Study “InveCeAb” (Brain Aging in Abbiategrasso)

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Health 2024年第1期16卷 22-36页

作者： Mauro Colombo Annalisa Davin Elena Rolandi Michele Rossi Riccardo Ferrari erica Spina Antonio Guaita Golgi Cenci Foundation Abbiategrasso Italy

Depression is a major health problem, especially for elderly people. According to the “homocysteine hypothesis of depression”, high homocysteine levels may cause depression of mood via cerebrovascular diseases. Whilst biologically plausible, such hypothesis needs yet confirmation. We aimed at: 1) studying the relationships between homocysteinemia (HCY) and depression in a community-dwelling cohort of people aged 70 to 75 years at baseline;2) investigating plasma levels of HCY and 3) comparing these levels between males and females, in the same population. We exploited the data from four waves (2010, 2012, 2014 and 2018) of the longitudinal study “InveCeAb”, with specific regard towards mood assessment, by Geriatric Depression Scale (GDS) scoring, and diagnosis of clinically relevant or subthreshold depression. HCY plasma levels were measured in the waves 2012, 2014 and 2018. Sample attrition was due mainly to death or overall worsening. No statistically significant differences were found in plasma homocysteine levels in each wave, according to depressive symptoms. No correlations were found between plasma HCY levels in each wave with their corresponding GDS scores, even after adjustment for folate and cobalamin blood concentrations. Dichotomized levels of HCY (≤15 vs >15 μM/l) were not associated with dichotomized GDS scores (≤4 vs higher), clinically relevant and subthreshold depression diagnosis and any antidepressive use, in any wave. First (2012) HCY levels increased with participants’ increasing age, cross-sectionally. Listwise HCY concentrations decreased along the 3 waves. HCY levels were always higher in males than in females. Our results may challenge the “homocysteine hypothesis” of depression, whilst supporting the role of high homocysteinemia as a marker of overall bad health.

关键词： Homocysteinemia Depression Aging Cohort

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AI情感陪伴开启智慧新生活

商业周刊（中文版） 2024年第5期 70-72页

作者： erica.CH 不详

数字经济经历了从PC的发明普及到移动互联网的兴盛,如今来到以AI为核心驱动力的新阶段。AI渗透现代人的日常起居,影响着他们的生活方式。部分机器人/宠物已迈入与人类进行感情交流的时代,AI情感陪伴机器人LOVOT正是AI大潮的产物。未来,... 详细信息

数字经济经历了从PC的发明普及到移动互联网的兴盛,如今来到以AI为核心驱动力的新阶段。AI渗透现代人的日常起居,影响着他们的生活方式。部分机器人/宠物已迈入与人类进行感情交流的时代,AI情感陪伴机器人LOVOT正是AI大潮的产物。未来,人类将更自然地和机器进行交流,对于机器的反馈需求也会逐步细化,社会生活的应用和服务形态势必将迎来又一轮变革。

关键词：移动互联网感情交流日常起居服务形态 AI 机器人情感陪伴核心驱动力

Neonatal Intestinal Obstruction in Acute Renal Failure in Premature Infant: A Case Report

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Open Journal of Pediatrics 2024年第2期14卷 338-343页

作者： Ondima Lucienne Irène Patricia Okiemy Niendet Cardinale Princilia Gandzali-Ngabe Pierre Eric Caryne Mboutol-Mandavo Bosseba Missengui Rhodia Hélène Akobande Nuptia erica Department of Paediatric Surgery CHU Brazzaville Brazzaville Congo Faculty of Health Sciences Marien Ngouabi University Brazzaville Congo Department of Nephrology and Dialysis Brazzaville University Hospital Brazzaville Congo

Introduction: Intestinal obstruction is a common cause of abdominal surgery in the neonate. Diagnosis is straightforward using standard radiology, and surgical technique depends on the underlying anatomical lesion. Peritoneal dialysis (PD) is an effective, albeit invasive, therapy for neonatal renal failure. We report a case of neonatal obstruction with severe renal failure treated by PD to highlight our hospital practice and possible remedies in a context of limited resources. Case Presentation: This was a female neonate of moderate prematurity admitted on day 4 of life for management of a flat neonatal obstruction. Radiological diagnosis suggested small bowel atresia. Biological tests revealed severe renal failure with creatinine levels of 416 micromoles per liter and blood urea of 27.1 micromoles per liter. Management consisted of preoperative peritoneal dialysis for 48 hours followed by laparotomy. The intraoperative diagnosis was GROSFELD type IIIa digestive atresia. The postoperative course was favourable, transit was resumed on day 5 and the patient returned home on day 12. Progress at 3 months was satisfactory. Conclusion: Neonatal intestinal obstruction with renal failure in premature infants is associated with a poor prognosis, even more so if there is a delay in treatment. Peritoneal dialysis seems to be a suitable alternative for this management in our working conditions with limited resources.

关键词： Neonate Occlusion Peritoneal Dialysis Case Report

Traumatic Diaphragmatic Hernia in Children: A Case Report

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Surgical Science 2024年第3期15卷 111-117页

作者： Lucienne Irène Patricia Ondima Rhodia Hélène Bosseba Missengue Nuptia erica Akobande Cardinale Princilia Okiemy Niendet Jean-Claude Mieret Caryne Mboutol-Mandavo Department of Pediatric Surgery Marien Ngouabi University Brazzaville Congo Department of Paediatric Surgery Hospital and University Centre (HUC) Brazzaville Congo

Introduction: Traumatic diaphragmatic hernia is a rare condition in children complicating closed or penetrating trauma to the abdomen and thorax. We report the case of an 11-year-old girl with a traumatic diaphragmatic hernia. Case Presentation: An 11-year-old girl was seen in the paediatric surgery department for a thoracolumbar spine deformity and intermittent chest pain. These symptoms occurred after a domestic accident involving a fall from a low wall onto the thoracolumbar spine 5 months previously. The diagnosis was suggested by the presence of a left hemithoracic hydroaera and confirmed by a thoraco-abdominal CT scan. Surgical exploration revealed a linear rupture of the entire left hemi-diaphragm with herniation of the stomach, small intestine, cecum, transverse colon and omentum. We performed a double-layer suture of the diaphragmatic rupture with a non-absorbable suture without edge rejuvenation after the reduction of the hernia. The outcome was favourable with normal postoperative radiographs at one year follow-up. Conclusion: Traumatic diaphragmatic hernia, although uncommon and difficult to diagnose, is a condition that is relatively easy to manage surgically, even if it is discovered late. In all cases of trauma to the thoracolumbar spine, regular follow-up and repeat X-rays are necessary if pain persists.

关键词： Hernia Diaphragm Trauma Child Case Report

Large Conventional Osteosarcoma of the Proximal Humerus in a 13-Year-Old Child: Case Report

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Open Journal of Pediatrics 2024年第2期14卷 297-304页

作者： Lucienne Irène Patricia Ondima Rhodia Hélène Bosseba Missengue Cardinale Princilia Okiemy Niendet Nuptia erica Akobande Jean Claude Mieret Caryne Mboutol-Mandavo Redy Atipo Galloye Judith Nsondé Malanda Jennifer Mave Sirimé Ngandzo Fabien Mouamba Faculty of Health Sciences Marien Ngouabi University Brazzaville Congo Paediatric Surgery Department Brazzaville University Hospital Centre Brazzaville Congo Department of General Surgery Brazzaville University Hospital Centre Brazzaville Congo Carcinology Department Brazzaville University Hospital Centre Brazzaville Congo Anatomo-Pathology Laboratory Brazzaville University Hospital Centre Brazzaville Congo

Introduction: Osteosarcoma is the most common primary malignant bone tumor in children. It is highly aggressive and has a poor prognosis. A late presentation modifies and makes difficult the management affecting the survival of children. We report the case of a large conventional osteosarcoma in a 13-year-old girl. Case Presentation: Adolescent girl admitted for painful swelling of the left shoulder with absolute functional impotence of the thoracic limb and severe anemia. The painful swelling was thought to have been caused by a minor trauma that had occurred six months previously. The patient’s general condition was poor, and she presented with a large, shiny, painful mass over the shoulder and upper 2/3 of the left arm, measuring 28 cm long by 28 cm wide and 57 cm in circumference, and a large fistulous axillary adenopathy. CT scan showed a tumour lesion of the left humerus with liver and lung metastases, raising suspicion of osteogenic osteosarcoma. The tumor was classified according to TNM staging: T2N1M1(a + b). Management was modified when uncontrolled bleeding developed. It consisted of an extended amputation of the left thoracic limb. Pathological analysis showed a high-grade conventional osteosarcoma. Quality improvement was obtained for thirty days, followed by the onset of dyspnea. The evolution was towards death at forty days post-operatively. Conclusion: Osteosarcoma is a highly aggressive cancer. Delayed treatment leads to a fatal outcome. Early diagnosis is one of the challenges to be met in order to improve survival.

关键词： Osteosarcoma Child Conventional Case Report

Vibration-based crack prediction on a beam model using hybrid butterfly optimization algorithm with artificial neural network

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Frontiers of Structural and Civil Engineering 2022年第8期16卷 976-989页

作者： Abdelwahhab KHATIR Roberto CAPOZUCCA Samir KHATIR erica MAGAGNINI Structural Section DICEA Polytechnic University of MarcheAncona 60131Italy Faculty of Civil Engineering Ho Chi Minh City Open UniversityHo Chi Minh City 700000Vietnam

Vibration-based damage detection methods have become widely used because of their advantages over traditional methods.This paper presents a new approach to identify the crack depth in steel beam structures based on vibration analysis using the Finite Element Method(FEM)and Artificial Neural Network(ANN)combined with Butterfly Optimization Algorithm(BOA).ANN is quite successful in such identification issues,but it has some limitations,such as reduction of error after system training is complete,which means the output does not provide optimal results.This paper improves ANN training after introducing BOA as a hybrid model(BOA-ANN).Natural frequencies are used as input parameters and crack depth as output.The data are collected from improved FEM using simulation tools(ABAQUS)based on different crack depths and locations as the first stage.Next,data are collected from experimental analysis of cracked beams based on different crack depths and locations to test the reliability of the presented technique.The proposed approach,compared to other methods,can predict crack depth with improved accuracy.

关键词： damage prediction ANN BOA FEM experimental modal analysis