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Effects of an ultra-high magnetic field up to 25 T on the phase transformations of undercooled Co-B eutectic alloy

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Journal of Materials Science & Technology 2021年第34期93卷 79-88页

作者： Yixuan He Yuhao Wua Fan Bu Chengxiong Zou Zhangchi Bian Qiliang huang Tie Liu Qiang Wang Jun Wang Jinshan Li eric Beaugnon State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi'an.710072China Center of Advanced Lubrication and Seal Materials Northwestern Polytechnical University.Xi'an710072China Key Laboratory of Electromagnetic Processing of Materials(Ministry of Education) Northeastern University.Shenyang110819China Univ.Grenoble Alpes INSA ToulouseUniv.Toulouse Paul SabatierEMFLCNRSLNCMIGrenoble38000France

While there have been multiple recent reports in the literature focusing on the effects of magnetic field on the phase transformation behaviors,the research conducted with an ultra-high magnetic field greater than 20 T is still *** the current study,the structure evolution of Co-B alloys are experimentally studied with *** effects of a 25 T magnetic field on the solidification behavior and the subsequent solid-state phase transformation behavior have been *** 25 T magnetic field is confirmed to have little effect on the homogeneous nucleation,but have some influence on the heterogeneous nucleation of Co_(3) B and Co_(23)B6 phases by modifying the wetting angleθ.The decomposition of Co_(23)B6 phase in the subsequent cooling process can be effectively suppressed by applying the 25 T magnetic *** present work might be helpful for not only theoretically understanding the influence of ultra-high magnetic field on the phase transformation behaviors but a potential technology of field-manipulation of magnetic materials.

关键词： Ultra-high magnetic field Non-equilibrium solidification Solid-state phase transformation Metastable phase

OsHYPK-mediated protein N-terminal acetylation coordinates plant development and abiotic stress responses in rice

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Molecular Plant 2022年第4期15卷 740-754页

作者： Xiaodi Gong Yaqian huang Yan Liang Yundong Yuan Yuhao Liu Tongwen Han Shujia Li Hengbin Gao Bo Lv Xiahe huang eric Linster Yingchun Wang Markus Wirtz Yonghong Wang Institute of Genetics and Developmental Biology Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China State Key Laboratory of Crop Biology College of Life SciencesShandong Agriculture UniversityTaianShandong 271018China State Key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China Centre for Organismal Studies Heidelberg University69120 HeidelbergGermany

N-terminal acetylation is one of the most common protein modifications in eukaryotes,and approximately 40%of human and plant proteomes are acetylated by ribosome-associated N-terminal acetyltransferase A(NatA)in a co-translational ***,the in vivo regulatory mechanism of NatA and the global impact of NatA-mediated N-terminal acetylation on protein fate remain ***,we identify Huntingtin Yeast partner K(HYPK),an evolutionarily conserved chaperone-like protein,as a positive regulator of NatA activity in *** found that loss of OsHYPK function leads to developmental defects in rice plant architecture but increased resistance to abiotic stresses,attributable to perturbation of the N-terminal acetylome and accelerated global protein ***,we demonstrated that OsHYPK is also a substrate of NatA and that N-terminal acetylation of OsHYPK promotes its own degradation,probably through the Ac/N-degron pathway,which could be induced by abiotic *** together,our findings suggest that the OsHYPK-NatA complex plays a critical role in coordinating plant development and stress responses by dynamically regulating NatA-mediated N-terminal acetylation and global protein turnover,which are essential for maintaining adaptive phenotypic plasticity in rice.

关键词： rice OsHYPK N-terminal acetylation protein turnover plant architecture stress response

Preliminary results on a near-real-time rock slope damage monitoring system based on relative velocity changes following the September 5,2022 M_(S) 6.8 Luding,China earthquake

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Earthquake Research Advances 2023年第1期3卷 31-36页

作者： Fan Xie Chen Liang Shigui Dai Bo Shao Huibao huang Jinhui Ouyang Li Li eric Larose Institute of Science and Technology China Three Gorges CorporationBeijing 100089China Key Laboratory of Earthquake Source Physics China Earthquake AdministrationBeijing 100081China Dadu River Hydropower Development Co. Ltd.Chengdu 610016China Sichuan Earthquake Agency Chengdu 610044China ISTerre CNRSand University Grenoble AlpesGrenobleFrance

Relative seismic velocity change(dv/v)is important for monitoring changes in subsurface material properties and evaluating earthquake-induced rock slope damage in a geological disaster-prone *** this paper,we present a rapid damage assessment on three slow-moving rock slopes by measuring dv/v decrease caused by the 2022 M_(S) 6.8 Luding earthquake in Southwest *** applying the stretching method to the cross-correlated seismic wavefields between sensors installed on each slope,we obtain earthquake-induced dv/v decreases of~2.1%,~0.5%,and~0.2%on three slopes at distances ranging from~86 to~370 km to the epicenter,***,based on seismic data recorded by 16 sensors deployed on the rock slope at a distance of~370 km away from the epicenter,a localized dv/v decease region was observed at the crest of the slope by calculating the spatial dv/v images before and after the *** also derive an empirical in situ stress sensitivity of -7.29×10^(-8)/Pa by relating the dv/v change to the measured peak dynamic *** results indicate that a rapid dv/v assessment not only can help facilitate on-site emergency response to earthquakeinduced secondary geological disasters but also can provide a better understanding of the subsurface geological risks under diverse seismic loadings.

关键词： Relative velocity change Rock slope damage Luding earthquake Space-time evolution

Genomic Analyses Yield Markers for Identifying Agronomically Important Genes in Potato

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Molecular Plant 2018年第3期11卷 473-484页

作者： Yangping Li Christophe Colleoni Junjie Zhang Qiqi Liang Yufeng Hu Holly Ruess Reinhard Simon Yinghong Liu Hanmei Liu Guowu Yu eric Schmitt Ghloe Ponitzki Guangjian Liu Huanhuan huang Feilong Zhan Lin Chen Yubi huang David Spooner Binquan huang College of Agronomy Sichuan Agricultural University Chengdu China Joint International Research Laboratory of Crop Resources and Genetic Improvement of Ministry of Education Sichuan Agricultural University Chengc)u China University of Lille CNRS UMR 8576-UGSF Lille France College of Life Science Sichuan Agricultural University Chengdu China Novogene Bioinformatics Institute Beijing China Vegetable Crops Research Unit USDA-Agricultural Research Service Department of Horticulture University of Wisconsin Madison Wl USA Integrated IT and Computational Research Unit International Potato Center Lima Peru Maize Research Institute Sichuan Agricultural University Chengdu China University of Lille CNRS UMR 8198 Evo Eco-Paleo Lille France Department of Plant Sciences University of Oxford Oxford UK These authors contributed equally to this article.

Wild potato species have substantial phenotypic and physiological diversity. Here, we report a comprehen- sive assessment of wild and cultivated potato species based on genomic analyses of 201 accessions of Solanum section Petota. We sequenced the genomes of these 201 accessions and identified 6 487 006 high-quality single nucleotide polymorphisms （SNPs） from 167 accessions in clade 4 of Solanum section Petota, including 146 wild and 21 cultivated diploid potato accessions with a broad geographic distribution. Genome-wide genetic variation analysis showed that the diversity of wild potatoes is higher than that of cultivated potatoes, and much higher genetic diversity in the agronomically important disease resistance genes was observed in wild potatoes. Furthermore, by exploiting information about known quantitative trait loci （QTL）, we identified 609 genes under selection, including those correlated with the loss of bitterness in tubers and those involved in tuberization, two major domesticated traits of potato. Phylogenetic analyses revealed a north-south division of all species in clade 4, not just those in the S. brevicaule complex, and further supported So candolleanum as the progenitor of cultivated potato and the monophyletic origin of cultivated potato in southern Peru. In addition, we analyzed the genome of S. candolleanum and identified 529 genes lost in cultivated potato. Collectively, the molecular markers generated in this study provide a valuable resource for the identification of agronomicaUy important genes useful for potato breeding.

关键词： potato Solanum section Petota genetic diversity molecular marker domestication phylogeny

Optimal central venous pressure during partial hepatectomy for hepatocellular carcinoma

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Hepatobiliary & Pancreatic Diseases International 2013年第5期12卷 520-524页

作者： Cheng-Xin Lin Ya Guo Wan Yee Lau Guang-Ying Zhang Yi-Ting huang Wen-Zheng He eric CH Lai Department of Anesthesiology First Affiliated Hospital of Guangxi Medical University Department of Hepatic and Biliary Surgery First Affiliated Hospital of Guangxi Medical University Faculty of Medicine The Chinese University of Hong Kong

BACKGROUND:Low central venous pressure(CVP) affects hemodynamic stability and tissue *** prospective study aimed to evaluate the optimal CVP during partial hepatectomy for hepatocellular carcinoma(HCC).METHODS:Ninety-seven patients who underwent partial hepatectomy for HCC had their CVP controlled at a level of 0 to 5 mmHg during hepatic parenchymal *** systolic blood pressure(SBP) was maintained,if possible,at 90 mmHg or *** B surface antigen was positive in 90 patients(92.8%) and cirrhosis in 84 patients(86.6%).Pringle maneuver was used routinely in these patients with clamp/unclamp cycles of 15/5 *** average clamp time was 21.4±8.0 *** patients were divided into 5 groups based on the CVP:group A:0-1 mmHg;B:1.1-2 mmHg;C:2.1-3 mmHg;D:3.1-4 mmHg and E:4.1-5 *** blood loss per transection area during hepatic parenchymal transection and the arterial blood gas before and after liver transection were ***:With active fluid load,a constant SBP ≥90 mmHg which was considered as optimal was maintained in 18.6% in group A(95% CI:10.8%-26.3%);39.2% in group B(95% CI:29.5%-48.9%);72.2% in group C(95% CI:63.2%-81.1%);89.7% in group D(95% CI:83.6%-95.7%);and 100% in group E(95% CI:100%-100%).The blood loss per transection area during hepatic parenchymal transection decreased with a decrease in *** to groups D and E,blood loss in groups A,B and C was significantly less(analysis of variance test,P<0.05).Compared with the baseline,the blood oxygenation decreased significantly when the CVP was *** excess and HCO 3-in groups A and B were significantly decreased compared with those in groups C,D and E(P<0.05).CONCLUSION:In consideration of blood loss,SBP,base excess and HCO 3-,a CVP of 2.1-3 mmHg was optimal in patients undergoing partial hepatectomy for HCC.

关键词： central venous pressure hepatectomy blood loss

Role of endogenous Schwann cells in tissue repair after spinal cord injury

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Neural Regeneration Research 2013年第2期8卷 177-185页

作者： Shu-xin Zhang Fengfa huang Mary Gates eric G. Holmberg Spinal Cord Society Research Center Department of Chemistry University of Alaska

Schwann cells are glial cells of peripheral nervous system, responsible for axonal myelination and ensheathing, as well as tissue repair following a peripheral nervous system injury. They are one of several cell types that are widely studied and most commonly used for cell transplantation to treat spinal cord injury, due to their intrinsic characteristics including the ability to secrete a variety of neurotrophic factors. This mini review summarizes the recent findings of endogenous Schwann cells after spinal cord injury and discusses their role in tissue repair and axonal regeneration. After spinal cord injury, numerous endogenous Schwann cells migrate into the lesion site from the nerve roots, involving in the construction of newly formed repaired tissue and axonal myelination. These invading Schwann cells also can move a long distance away from the injury site both rostrally and caudally. In addition, Schwann cells can be induced to migrate by minimal insults （such as scar ablation） within the spinal cord and integrate with astrocytes under certain circumstances. More importantly, the host Schwann cells can be induced to migrate into spinal cord by transplantation of different cell types, such as exogenous Schwann cells, olfactory ensheathing cells, and bone marrow-derived stromal stem cells. Migration of endogenous Schwann cells following spinal cord injury is a common natural phenomenon found both in animal and human, and the myelination by Schwann cells has been examined effective in signal conduction electrophysiologically. Therefore, if the inherent properties of endogenous Schwann cells could be developed and utilized, it would offer a new avenue for the restoration of injured spinal cord.

关键词： neural regeneration spinal cord injury Schwann cells spinal cord injury tissue repair axonalregeneration myelination rat scar ablation astrocytes cell transplantation rose Bengal olfactoryensheathing cells bone marrow stromal cell grant-supported paper neuroregeneration

Genetic profiles of familial late-onset Alzheimer’s disease in China:The Shanghai FLOAD study

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Genes & Diseases 2022年第6期9卷 1639-1649页

作者： Xin-Yi Xie Qian-Hua Zhao Qiang huang a eric Dammer Sheng-di Chen Ru-Jing Ren Gang Wang the Alzheimer’s Disease Neuroimaging Initiative Department of Neurology and Institute of Neurology Ruijin Hospital Affiliated with Shanghai JiaoTong University School of MedicineShanghai 200025PR China Institute of Neurology Huashan HospitalFudan UniversityShanghai 200040PR China National Clinical Research Center for Aging and Medicine Huashan HospitalFudan UniversityShanghai 200040PR China Department of Biochemistry Center for Neurodegenerative DiseaseEmory University School of MedicineAtlantaGA 30322USA

Compared with early-onset familial AD(FAD),the heritability of most familial lateonset Alzheimer’s disease(FLOAD)cases still remains ***,there are few reported genetic profiles of FLOAD to *** the present study,targeted sequencing of selected candidate genes was conducted for each of 90 probands with FLOAD and 101 unrelated matched normal controls among Chinese Han *** show a significantly lower rate of mutation in APP and PSENs,and APOE e4 genetic risk is higher for *** the Chinese FLOAD population,the most frequent variant was CR1 rs116806486[5.6%,95%CI(1.8%,12.5%)],followed by coding variants of TREM2(4.4%,95%CI(1.2%,10.9%))and novel mutations of ACE[3.3%,95%CI(0.7%,9.4%)].Next,we found that novel pathogenic mutations in ACE including frame-shift and nonsense mutations were in association with FLOAD regardless of APOE e4 *** from the Alzheimer’s disease Neuroimaging Initiative(ADNI)database also supported this finding in different *** of in vitro analysis suggest that frame-shift and nonsense mutations in ACE may be involved in LOAD through decreased ACE protein levels without affecting direct processing of APP.

关键词： ACE Alzheimer’s disease Familial late-onset Alzheimer’s disease Gene Mutation

Taxonomic studies of some often over-looked Diaporthomycetidae and Sordariomycetidae

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Fungal Diversity 2021年第6期111卷 443-572页

作者： Shi-Ke huang Kevin D.Hyde Ausana Mapook Sajeewa S.N.Maharachchikumbura Jayarama D.Bhat eric H.C.McKenzie Rajesh Jeewon Ting-Chi Wen State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering Key Laboratory of Green Pesticide and Agricultural BioengineeringMinistry of EducationGuizhou UniversityGuiyang 550025China The Engineering Research Center of Southwest Bio-Pharmaceutical Resources Ministry of EducationGuizhou UniversityGuiyang 550025Guizhou ProvinceChina Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand The Mushroom Research Centre Guizhou UniversityGuiyang 550025China Institute of Plant Health Zhongkai University of Agriculture and EngineeringHaizhu DistrictGuangzhou 510225China School of Life Science and Technology University of Electronic Science and Technology of ChinaChengdu 611731China Department of Botany Goa UniversityGoaIndia Present Address:Goa Velha India Manaaki Whenua-Landcare Research Private Mail Bag 92170AucklandNew Zealand Department of Health Sciences Faculty of Medicine and Health SciencesUniversity of MauritiusReduitMauritius

Sordariomycetes is an earlier-introduced and one of the widely distributed class of *** class was initially clas-sified based on morphology in having inoperculate and unitunicate *** the development of DNA based phylogenetic analysis,several undetermined or polyphyletic members of Sordariomycetes were ***,not all species belonging to this class have been sequenced and *** are a number of species,especially those old and poorly studied ones which have never been sequenced before and not even recollected again for further taxonomic *** of the main objective in this study is to revise and update the taxonomy of several well-known early and poorly studied spe-cies whose classification are still ***,we re-examined the type materials and/or authentic specimens together to explore 74 relatively poorly-studied genera,which mainly belong to Boliniales,Calosphaeriales,Chaetosphaeriales,Jobellisiales,and Sordariales classified under Diaporthomycetidae and *** provide descriptions,notes,figures and/or drawings and discussed their phylogenetic *** a result,the monotypic Jobellisiales is transferred from Hypocreomycetidae to *** on phylogenetic analysis,the polyphyletic Lasiosphaeriaceae is divided into five families,Bombardiaceae(Apodospora,Bombardia,Bombardioidea,Fimetariella and Ramophialophora),Lasiosphaeriaceae(Anopodium,Bellojisia,Corylomyces,Lasiosphaeria,Mammaria and Zopfiella),Lasiosphaeridaceae(Lasiosphaeris),Strattoniaceae(Strattonia)and Zygospermellaceae(Episternus and Zygospermella).In addition,a new family Neoschizotheciaceae is established based on *** of the type species of Boothiella,Stel-latospora,Sulcatistroma and Tengiomyces placed them in Sordariaceae,Chaetomiaceae,Hypocreales and Coronophorales,*** classify the genera lacking molecular data based on their morphology and expect them to be recollected;that is

关键词： 43 new taxa Boliniales Calosphaeriales Helminthosphaeriaceae Jobellisiales Sordariales Sordariomycetes

万州零售淡水鱼中副溶血性弧菌的污染状况与特征研究

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食品与发酵工业 2024年第16期50卷 242-248页

作者：赵力丁国英朱秋昊刘奇黄玲冬肖国生赵峰重庆三峡学院生物与食品工程学院重庆404100

为了解万州零售淡水鱼中副溶血性弧菌(Vibrio parahaemolyticus,Vp)污染状况、血清型、耐药性及亲缘关系,于2022年—2023年采集万州零售淡水鱼共141份,根据GB 4789.7—2013《食品安全国家标准食品微生物学检验副溶血性弧菌检验》分离Vp... 详细信息

为了解万州零售淡水鱼中副溶血性弧菌(Vibrio parahaemolyticus,Vp)污染状况、血清型、耐药性及亲缘关系,于2022年—2023年采集万州零售淡水鱼共141份,根据GB 4789.7—2013《食品安全国家标准食品微生物学检验副溶血性弧菌检验》分离Vp和定量,PCR法特异性扩增tlh、tdh、trh、toxR、pirA、T3SS1、T3SS2和T3SS2基因,用多重PCR检测血清型,纸片扩散法检测耐药性以及肠杆菌科基因间重复序列(enterobacterial repetitive intergenic consensus, eric)-PCR分析亲缘关系。结果显示,141份样品中总污染率为38.3%,阳性样品定量范围为1.5~1 100 MPN/g,花鲢污染率最高(66.7%)。Vp受季节和温度的影响,夏季污染率最高(57.1%)。54株Vp全部携带tlh、toxR和T3SS1基因,1株同时携带tdh和T3SS2α基因,未检测到trh、pirA和T3SS2β基因。血清分布较分散,分为9个O群,O1为优势群(33.3%)。54株Vp对苯唑西林、青霉素和氨苄西林耐药率分别为:100%、98.1%和90.7%,对头孢他啶、头孢曲松、庆大霉素、四环素、多西环素和米诺环素100%敏感。eric-PCR分析表明,存在与临床分离株有遗传相似的致病菌株。该研究结果可为淡水鱼养殖、消费和临床治疗Vp导致的食源性疾病提供理论依据。

关键词：副溶血性弧菌淡水鱼毒力基因血清型耐药性 eric-PCR