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Cardiac tamponade as a rare complication after giant coronary fistula percutaneous closure

World Journal of Cardiovascular Diseases 2013年第2期3卷 215-217页

作者： Pablo Diez Villanueva Fernando Sarnago Cebada enrique gutierrez ibanes Ricardo Sanz-Ruiz Jaime Elizaga-Corrales Francisco Fernandez-Aviles Cardiology Department Hospital General Universitario Gregorio MaranonMadridSpain

We present the case of an unusual complication after percutaneous closure of a giant coronary artery fis-tula. A 76-year-old man with previous admissions due to right heart failure and previous history of atrial fibrillation under acenocumarol, was admitted to our hospital for new onset of symptoms, characterized by progressive dyspnoea and peripheral edema. Physical examination revealed signs of congestive heart failure and a continuous murmur loudest along the lower sternal border. X-Ray showed cardiomegaly due to right chambers dilatation. Transthoracic echocardiography showed right chambers pressure and volume overload, with right ventricular enlargement and dysfunction, tricuspid annulus dilatation and severe tricuspid regurgitation. Cardiac catheterization showed significant elevation of right atrial pressure, as well as significant step-up of oxygen saturation in this chamber. Coronary angiography revealed the presence of a large fistula between the circumflex coronary artery (CCA) and coronary sinus (CS), with severe dilation of the CCA (maximum diameter20 mm). An Amplatzer? PDA was implanted in a distal elbow of the fistula with initailly good results. Anticoagulant therapy was then reinitiated, and a few days later, the patient developed clinical worsening of heart failure and dyspnoea. Echocardiogram showed significant pericardial effusion. Pleuropericardial window was then made draining a500 cm3 of bloody pericardial effusion. The postoperative outcome was excellent, with symptomatic relief and no signs of heart failure.

关键词： Giant Coronary Fistula Circumflex Coronary Artery Coronary Sinus Percutaneous Transcatheter Closure Pericardial Effusion Cardiac Tamponade

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Stroke mechanisms and outcomes of isolated symptomatic basilar artery stenosis

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Stroke & Vascular Neurology 2019年第4期4卷 189-197页

作者： Edgar A Samaniego Amir Shaban Santiago Ortega-gutierrez Jorge A Roa David M Hasan Colin Derdeyn Biyue Dai Harold Adams enrique Leira Neurology Neurosurgery and RadiologyUniversity of Iowa Hospitals and ClinicsIowa CityIowaUSA Neurology University of Iowa Hospitals and ClinicsIowa CityIowaUSA Neurology and Neurosurgery University of Iowa Hospitals and ClinicsIowa CityIowaUSA Neurosurgery University of Iowa Hospitals and ClinicsIowa CityIowaUSA Radiology University of Iowa Hospitals and ClinicsIowa CityIowaUSA Biostatistics and Public Health University of Iowa Hospitals and ClinicsIowa CityIowaUSA

background While diffuse atherosclerotic disease affecting the posterior circulation has been described extensively,the prevalence,natural history and angiographic characteristics of isolated symptomatic basilar artery stenosis(ISBAS)remain *** We reviewed our prospective institutional database to identify patients with≥50% symptomatic basilar artery(BA)stenosis without significant atherosclerotic burden in the vertebral or posterior cerebral *** mechanism,collateral circulation,and degree and length of stenosis were *** primary outcome was time from index event to new transient ischaemic attack(TIA),acute ischaemic stroke(AIS)or *** outcome variables included modified Rankin Scale(mRS)score on discharge and last *** Of 6369 patients with AIS/TIA,91(1.43%)had ***-three(80.2%)patients presented with AIS and 18(19.8%)with ***-nine(31.9%)were women and the median age was 66.8±13.6 *** mean follow-up time was 2.7 *** most common stroke mechanism was artery-to artery thromboembolism(45.2%),followed by perforator occlusion(28.7%)and flow-dependent/hypoperfusion(15.1%).The percentage of stenosis was lower in patients who had favourable outcome compared with those with mRS 3-6 on discharge(78.3±14.3 vs 86.9±14.5,p=0.007).Kaplan-Meier curves showed higher recurrence/death rates in patients with≥80% stenosis,mid-basilar location and poor collateral *** 13% of patients with ISBAS presented with complete BA *** ISBAS is an uncommon(1.43%)cause of TIA and *** in their 60s are mostly affected,and artery-to artery embolism is the most common stroke ***-basilar location,≥80% stenosis and poor collateral circulation are important factors associated with worse prognosis.

关键词： stenosis basilar artery

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A Transactive Energy Model for Smart Metering Systems Using Blockchain

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CSEE Journal of Power and Energy Systems 2021年第5期7卷 943-953页

作者： Juan C.Olivares-Rojas enrique Reyes-Archundia Jose A.gutierrez-Gnecchi Ismael Molina-Moreno Jaime Cerda-Jacobo Arturo Mendez-Patino National Technological Institute of Mexico/Technological Institute of Morelia-Division of Graduate Studies and Research MoreliaMichoacan 58120Mexico. School of Electrical Engineering Michoacan University of San Nicolas de HidalgoMorelia 58030.Mexico

The lowering cost of electricity generation technologies by renewable means has caused the role of end-users to change from being a simple consumer to a producer of their *** new role has been called a prosumer and has contributed to modifying electricity markets,by allowing prosumers to merchandize the energy surplus to electricity companies and other *** fundamental key to any economic transaction is trust between the ***,new technologies,such as blockchain,are transforming transaction security,and allowing decentralization of the smart power *** study presents the development of a transactional model of electrical energy using the infrastructure of smart metering and blockchain systems to allow the commercialization of electrical energy by *** results show that for the Mexican electricity market,they can he good alternatives hy reducing subsidies and being more profitable than current rates.

关键词： Data visualization fault diagnosis IoT network photovoltaic system wireless remote monitoring

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The Genome of Cucurbita argyrosperma (Silver- Seed Gourd) Reveals Faster Rates of Protein- Coding Gene and Long Noncoding RNA Turnover and Neofunctionalization within Cucurbita

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Molecular Plant 2019年第4期12卷 506-520页

作者： Josue Barrera-Red on do enrique Ibarra-Laclette Alejandra Vazquez-Lobo Yocelyn T. gutierrez-Guerrero Guillermo Sanchez de la Vega Daniel Pinero Salvador Montes-Hernandez Rafael Lira-Saade Luis E. Eguiarte Departamento de Ecologia Evolutiva Instituto de Ecologia Universidad Nacional Aut6noma de Mexico Circuito Exterior s/n Anexo al Jardin Bot合nico 04510 Ciudad de Mexico Mexico Departamento de Estudios Moleculares Avanzados Instituto de Ecologia A.C. Carretera Antigua a Coatepec No. 351 Col. El Haya. C.P. Xalapa Veracruz 91070 Mexico Centro de Investigaciones en Biodiversidad y Conservacion Universidad Autdnoma del Estado de Morelos Av. Universidad 1001 Col. Chamilpa Cuernavaca Morelos 62209 Mexico Campo Experimental Bajio Instituto Nacional de In vestigaciones Forestales Agricolas y Pecuarias (INIFAP) Km 6.5 Carretera Celaya-San Miguel de Allen de Celaya Guanajuato 38110 Mexico UBIPRO Facultad de Estudios Superiores Iztacala Universidad Nacional Autdnoma de Mexico Av. de los Barrios #1 Col. Los Reyes Iztacala Tlanepantla Edo. de Mex 54090 Mexico

Whole-genome duplications are an important source of evolutionary novelties that change the mode and tempo at which genetic elements evolve within a genome. The Cucurbita genus experienced a wholegenome duplication around 30 million years ago, although the evolutionary dynamics of the coding and noncoding genes in this genus have not yet been scrutinized. Here, we analyzed the genomes of four Cucurbita species, in eluding a newly assembled genome of Cucurbita argyrosperma, and compared the gene con tents of these species with those of five other members of the Cucurbitaceae family to assess the evolutionary dynamics of protein-coding and long intergenic noncoding RNA (lincRNA) genes after the genome duplication. We report that Cucurbita genomes have a higher protein-coding gene birth-death rate compared with the genomes of the other members of the Cucurbitaceae family. C. argyrosperma gene families associated with pollination and transmembrane transport had significantly faster evolutionary rates. lincRNA families showed high levels of gene turnover throughout the phylogeny, and 67.7% of the lincRNA families in Cucurbita showed evidence of birth from the neofunctionalization of previously existing protein-coding genes. Collectively, our results suggest that the whole-genome duplication in Cucurbita resulted in faster rates of gene family evolution through the neofunctionalization of duplicated genes.

关键词： Cucurbita argyrosperma, comparative genomics molecular evolution neofunctionalization long noncoding RNA whole-genome duplication

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Irrigation of Romaine Lettuce (Lactuca sativa)Using Wastewater Treated byNon-Conventional Technologies

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World Journal of Engineering and Technology 2017年第5期5卷 1-11页

作者： Manuel enrique Lopez Sepulveda Santiago gutierrez Ruiz Antonio Lineiro Bullon Jose Maria Quiroga Alonso Department of Environmental Technologies(Av Republica Saharaui S/N Faculty of Marine and Environmental Sciences(CASEM)CP11510 Puerto RealCadizSpain

The aim of this study was to assess the capacity for reuse of wastewater treated in stabilisation ponds and subsequently reclaimed by means of different filtration systems at pilot scale. An analysis of filtered water showed turbidity values of below 5 NTU, a total suspended solids (TSS) content of 7 mg/l, and Escherichia coli values of up to 1.6 log CFU/100 ml. These results fall within the parameters stipulated in RD 1620/2007 Spanish Water Reuse Regulations governing the reuse of reclaimed wastewater for agricultural purposes. The water reclaimed by means of filtration systems was used to irrigate Romainelettuce (Lactuca sativa longifolia), comparing growth with that of the same variety irrigated with water from the supply network. The results showed a mean difference in lettuce growth of up to 300% in favour of the crop irrigated with reclaimed water.

关键词： Reclamation, Reutilisation, Small Communities, Intermittent Sand Filters,Infiltration-Percolation, Stabilisation Ponds, Artificial Wetlands

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Increased myo-inositol in the posterior cingulate cortex in first-episode major depressive patients

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Advances in Bioscience and Biotechnology 2013年第6期4卷 45-52页

作者： Lily Magally Granados-Dominguez enrique O.Flores-gutierrez Sarael Alcauter Juan Jose Cervantes Marina Torres-Alvarez Maria Corsi-Cabrera Laboratory for Sleep Research Faculty of PsychologyUniversidad Nacional Autonoma de Mexico(UNAM)Mexico CityMexico Sub-Department of Clinical Investigations Instituto Nacional de Psiquiatria Ramon de la Fuente MunizMexico CityMexico

Major depressive disorder (MDD) is a severe, disabling pathology characterized, in addition to affective, cognitive and motor symptoms, by self-focused attention and rumination. During recursive self-focused processes and rumination, the posterior cingulate cortex (PCC) is activated. In vivo proton magnetic resonance spectroscopy (MRS) is a noninvasive imaging technique that can directly assess living biochemistry in localized brain regions. The aim of this study, therefore, was to use 1H-MRS as a means of analyzing brain metabolites in the PCC of a group of first-episode, unmedicated MDD patients. PCC metabolite levels were analyzed at 3-T in a single voxel located bilaterally over the PCC in 7 patients diagnosed for the first time with MDD and with no previous pharmacological treatment, as well as in 9 control subjects. Differences in metabolite levels between groups were compared using independent t-tests. Myo-inositol was significantly higher, and NAA + NAAG/Cr significantly lower, in MDD patients than in controls. The other brain metabolites showed no statistical differences. The present results suggest that alterations in PCC metabolite levels are likely involved in MDD pathophysiology, and may help to improve our understanding of MDD and the role of the PCC in some symptoms of depression.

关键词： Major Depressive Disorder Posterior Cingulate Cortex Metabolites ^(1)H-MRS Myo-Inositol N-Acetyl-Aspartate

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Coronary physiology assessment in the catheterization laboratory

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World Journal of Cardiology 2015年第9期7卷 525-538页

作者： Felipe Díez-delhoyo enrique Gutiérrez-ibanes Gerard Loughlin Ricardo Sanz-Ruiz María Eugenia Vázquez-álvarez Fernando Sarnago-Cebada Rocío Angulo-Llanos Ana Casado-Plasencia Jaime Elízaga Francisco Fernández Avilés Diáz Instituto de Investigación Sanitaria Gregorio Maranón Servicio de CardiologíaDepartamento de MedicinaUniversidad Complutense de Madrid

Physicians cannot rely solely on the angiographic appearance of epicardial coronary artery stenosis when evaluating patients with myocardial ischemia. Instead, sound knowledge of coronary vascular physiology and of the methods currently available for its characterization can improve the diagnostic and prognostic accuracy of invasive assessment of the coronary circulation, and help improve clinical decision-making. In this article we summarize the current methods available for a thorough assessment of coronary physiology.

关键词： Coronary heart disease Coronary physiology Endothelial dysfunction Microvascular dysfunction Fractional flow reserve Coronary flow reserve Index of microcirculatory resistance

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Clinical-pathological and molecular characterization of long-term survivors with advanced non-small cell lung cancer

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Cancer Biology & Medicine 2020年第2期17卷 444-457页

作者： Juan Moreno-Rubio Santiago Ponce Rosa Alvarez Maria Eugenia Olmedo Sandra Falagan Xabier Mielgo Fatima Navarro Patricia Cruz Luis Cabezon-gutierrez Carlos Aguado Gonzalo Colmenarejo Marta Munoz-Fernandez de Leglaria Ana Belen Enguita Maria Cebollero Amparo Benito Isabel Alemany Carolina del Castillo Ricardo Ramos Ana Ramirez de Molina enrique Casado Maria Sereno Ana Ramirez de Molina1 Enrique Casado5Maria Sereno5 XIMDEA Food InstituteCEI UAM+CSICMadrid 28702Spain 12 de Octubre University Hospital Madrid 28041Spain Gregorio Maranon University Hospital Madrid 28009Spain Ramon y Cajal University Hospital Madrid 28034Spain Infanta Sofia University Hospital San Sebastian De Los ReyesMadrid 28702Spain Fundacion Alcorcon University Hospital AlcorconMadrid 28922Spain Prlncipe de Asturias University Hospital Alcala De HenaresMadrid 28805Spain La Paz University Hospital Madrid 28046Spain University Hospital of Torrejon Torrejon De ArdozMadrid 28850Spain Clinico San Carlos University Hospital Madrid 28040Spain Parque Cientifico de Madrid Foundation Madrid 28049Spain

Objective:Long-term survivors(LS)of non-small cell lung cancer(NSCLC)without driver alterations,displaying an overall survival(OS)of more than 3 years,comprise around 10%of cases in several series treated with *** are classical prognosis factors for these cases[stage,Eastern Cooperative Oncology Group(ECOG),etc.],but more data are required in the *** this multi-center study,we focused on LS of advanced NSCLC with OS above 36 months to perform a clinical-pathological and molecular ***:In the first step,we conducted a clinical-pathological characterization of the ***,we carried out a genetic analysis by comparing LS to a sample of short-term survivors(SS)(with an OS less than 9 months).We initially used whole-genome RNA-seq to identify differentiating profiles of LS and SS,and later confirmed these with reverse transcription-polymerase chain reaction(RT-PCR)for the rest of the ***:A total of 94 patients were included,who were mainly men,former smokers,having adenocarcinoma(AC)-type NSCLC with an ECOG of *** obtained an initial differential transcriptome expression,displaying 5 over-and 33 under-expressed genes involved in different pathways:namely,the secretin receptor,surfactant protein,trefoil factor 1(T FF1),serpin,Ca-channels,and Tolllike receptor(TLRs)***,RT-PCR analysis of 40(20 LS/20 SS)samples confirmed that four genes(surfactant proteins and SFTP)were significantly down-regulated in SS compared to LS by using an analysis of covariance(ANCOVA)model:SFTPA1(P=0.023),SFTPA2(P=0.027),SFTPB{P=0.02),and SFT PC(P=0.047).Conclusions:We present a sequential genetic analysis of a sample of NSCLCLS with no driver alterations,obtaining a differential RNA-seq/RT-PCR profile showing an abnormal expression of SF genes.

关键词： Long-term survivors non-small cell lung cancer surfactant proteins

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Physical-Mathematical Foundations of the Penman Equation from the Perspective of the First Law of Thermodynamics and Energy Balance Theory

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Journal of Water Resource and Protection 2017年第12期9卷 1377-1390页

作者： Martín Mundo-Molina enrique De Coss-Gomez Investigation Centre Faculty of Engineer Autonomous University of Chiapas Tuxtla Gutierrez Mexico Investigation Centre CIDESTA Tuxtla Gutierrez Mexico

The evapotranspiration is indispensable for the planning and management of water resources in watersheds and for the design of important engineering projects. The accuracy of its estimation depends, among other things, on the proper determination of the date and frequency of irrigation. One of the most accurate equations for estimating the reference crop evapotranspiration (ETo) is the Penman-Monteith equation, which was derived from the Penman equation published in 1948, which in turn is based on the energy balance equation. In this paper we present the theoretical foundations of Penman’s equation from the perspective of the first law of thermodynamics and the theory of energy balance as a contribution for the students and engineers who use Penman’s or Penman-Monteith equations in a utilitarian way within the historical and theoretical framework of the origin of this equation.

关键词： Evapotranspiration Penman Penman-Monteith Irrigation Requirement

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Comparative study of breast cancer in Mexican and Mexican-American women

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Health 2010年第9期2卷 1040-1048页

作者： Maria Elena Martinez Luis enrique gutierrez-Millan Melissa Bondy Adrian Daneri-Navarro Maria Mercedes Meza-Montenegro Ivan Anduro-Corona Ma Isabel Aramburo-Rubio Luz Maria Adriana Balderas-Pena Jose Adelfo Barragan-Ruiz Abenaa Brewster Graciela Caire-Juvera Juan Manuel Castro-Cervantes Mario Alberto Chavez Zamudio Giovanna Cruz Alicia Del Toro-Arreola Mary EEdgerton Maria Rosa Flores-Marquez Ramon Antonio Franco-Topete Helga Garcia Susan Andrea gutierrez-Rubio Karin Hahn Luz Margarita Jimenez-Perez Ian KKomenaka Zoila Areli Lopez Bujanda Dihui Lu Gilberto Morgan-Villela James LMurray Jesse NNodora Antonio Oceguera-Villanueva Miguel Angel Ortiz Martinez Laura Perez Michel Antonio Quintero-Ramos Aysegul Sahin Jeong Yun Shim Maureen Stewart Gonzalo Vazquez-Camacho Betsy Wertheim Rachel Zenuk Patricia Thompson Arizona Cancer Center and Mel and Enid Zuckerman College of Public Health University of ArizonaTucsonUSA Departamento de Investigaciones Cientificas y Tecnologicas Universidad de SonoraHermosilloMexico University of Texas M.D.Anderson Cancer Center HoustonUSA Departamento de Fisiologia Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMexico Instituto Tecnologico de Sonora Ciudad ObregónMexico Instituto Mexicano del Seguro Social HermosilloMexico Instituto Mexicano del Seguro Social CMNOGuadalajaraJalisco Centro de Investigacion en Alimentacion y Desarrollo HermosilloMexico Instituto Mexicano del Seguro Social Ciudad ObregonMexico OPD Hospital Civil de Guadalajara GuadalajaraMexico Departamento de Salud Publica Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMexico Maricopa Medical Center Department of SurgeryPhoenixUSA University of North Carolina Lineberger Cancer CenterChapel HillUSA Arizona Cancer Center and Department of Family and Community Medicine University of ArizonaTucsonUSA Instituto Jalisciense de Cancerologia GuadalajaraMexico

Breast cancer is the number one cause of can- cer deaths among Hispanic women in the United States, and in Mexico, it recently became the primary cause of cancer deaths. This malign- nancy represents a poorly understood and un- derstudied disease in Hispanic women. The ELLA Binational Breast Cancer Study was es- tablished in 2006 as a multi-center study to as- sess patterns of breast tumor markers, clinical characteristics, and their risk factors in women of Mexican descent. We describe the design and implementation of the ELLA Study and provide a risk factor comparison between women in the U.S. and those in Mexico based on a sample of 765 patients (364 in the U.S. and 401 in Mexico). Compared to women in Mexico, U.S. women had significantly (p < 0.05) lower parity (3.2 vs. 3.9 mean live births) and breastfeeding rates (57.5% vs. 80.5%), higher use of oral contraceptives (60.7% vs. 50.1%) and hormone replacement therapy (23.3% vs. 7.6%), and higher family history of breast cancer (15.7% vs. 9.0%). Re- sults show that differences in breast cancer risk factor patterns exist between Mexico and U.S. women. We provide lessons learned from the conduct of our study. Binational studies are an important step in understanding disease pat- terns and etiology for women in both countries.

关键词： Binational Study Breast Cancer Hispanics Mexico United States

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