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Tailoring chiral optical properties by femtosecond laser direct writing in silica

Light(Science & Applications) 2023年第3期12卷 366-378页

作者： Jiafeng Lu Jing Tian Bertrand Poumellec enrique Garcia-Caurel Razvigor Ossikovski Xianglong Zeng Matthieu Lancry Institut de Chimie Moléculaire et des Matériaux d’Orsay UniversitéParis SaclayOrsay91405France Key Laboratory of Specialty Fiber Optics and Optical Access Networks Joint International Research Laboratory of Specialty Fiber Optics and Advanced CommunicationShanghai Institute for Advanced Communication and Data ScienceShanghai UniversityShanghai200444China LPICM CNRSEcole PolytechniqueInstitut Polytechnique de ParisPalaiseau91128France

An object that possesses chirality,that is,having its mirror image not overlayed on itself by rotation and translation,can provide a different optical response to a left-or right-handed circular polarized *** nanostructures may exhibit polarization-selective optical properties that can be controlled for micro-to-nano optical element *** attractive way to induce such complex nanostructures in three-dimension in glass is femtosecond laser direct ***,the mechanism of femtosecond laser induced chirality remains to be unveiled due to complex physical and chemical processes occurring during the ultrashort light-matter ***,a phenomenological model is proposed and is built on two-layers phase shifters to account for this laser-induced optical chirality in an initially achiral material(silica glass).This model is based on the observation that femtosecond laser induced nanogratings own two principal contributions to its aggregate birefringent response:a form and a stress-related *** refining this formalism,a multilayer approach is developed to imprint on demand optical *** up to+/-60°at 550 nm within an optimal 80μm thickness in silica glass are possible,corresponding to the highest value in a glass to *** results provide new insights of circular-optical control in micro-nano optical manufacturing and open new opportunities for photonics applications.

关键词： polarization silica circular

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Evidences supporting the vascular etiology of post-double balloon enteroscopy pancreatitis: Study in porcine model

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World Journal of Gastroenterology 2017年第34期23卷 6201-6211页

作者： Rafael Latorre Octavio López-Albors Federico Soria Esther Morcillo Pilar Esteban enrique Pérez-Cuadrado-Robles enrique Pérez-Cuadrado-Martínez Department of Anatomy and Comparative Pathology University of Murcia Minimally Invasive Surgery Centre Jesús Usón Department of Gastroenterology Small Bowel UnitMorales Meseguer Hospital

Double balloon enteroscopy(DBE) is an endoscopic technique broadly used to diagnose and treat small bowel diseases. Among the associated complications of the oral DBE, post-procedure pancreatitis has taken the most attention due to its gravity and the thought that it might be associated to the technique itself and anatomical features of the pancreas. However, as the etiology has not been clarified yet, this paper aims to review the published literature and adds new results from a porcine animal model. Biochemical markers, histological sections and the vascular perfusion of the pancreas were monitored in the pig during DBE practice. A reduced perfusion of the pancreas and bowel, the presence of defined hypoxic areas and disseminated necrotic zones were found in the pancreatic tissue of pigs. All these evidences contribute to support a vascular distress as the most likely etiology of the post-DBE pancreatitis.

关键词： Double balloon enteroscopy Pancreas Animal model Pancreatitis Pig

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Hematotesticular barrier is altered from early stages of liver cirrhosis:Effect of insulin-like growth factor 1

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World Journal of Gastroenterology 2004年第17期10卷 2529-2534页

作者： Inma Castilla-Cortázar Nieves Diez María García-Fernández Juan enrique Puche Fernando Diez-Caballero Jorge Quiroga Matías Díaz-Sánchez Alberto Castilla Amelia Díaz Casares Isabel Varela-Nieto Jesǘs Prieto Salvador gonzález-Barón Department of Human Physiology University of NavarraPamplonaNavarraSpain Department of Human physiologySchool of MedicineUniversity of MlagaMalagaSpain Department of Human Physiology University of NavarraPamplonaNavarraSpain Department of Human Physiology School of MedicineUniversity of MálagaMalagaSpain Instituto de Investigaciones Biomédicas "Alberto Sols" Consejo Superior de Investigaciones CientificasUniversidad Autónoma de Madrid (CSIC-UAM)MadridSpain Supported by the Spanish Program I+DSAF 99/0072 and SAF 2001/1672 Department of Internal Medicine Hospital SierrallanaTollelavega and School of MedicineUniversity of the Basque Country-Vitoria-GasteizSpain Instituto de Investigaciones Biomedicas"Alberto Sols"Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid(CSIC-UAM) MadridSpain Department of Internal Medicine Liver Unit University of Navarra PamplonaNavarraSpain

AIM:The pathogenesis of hypogonadism in liver cirrhosis is not well *** results from our laboratory showed that IGF-1 deficiency might play a pathogenetic role in hypogonadism of *** administration of IGF-1 for a short period of time reverted the testicular atrophy associated with advanced experimental cirrhosis. The aim of this study was to establish the historical progression of the described alterations in the testes, explore testicular morphology,histopathology,cellular proliferation,integrity of testicular barrier and hypophyso- gonadal axis in rats with no ascitic cirrhosis. METHODS:Male Wistar rats with histologically-proven cirrhosis induced with carbon tetrachloride(CCI_4)for 11 wk, were allocated into two groups(n=12,each)to receive recombinant IGF-1(2 μg/100 gd,sc)for two weeks or *** rats receiving vehicle were used as control group(n=12). RESULTS:Compared to controls,rats with compensated cirrhosis showed a normal testicular size and weight and very few histopathological testicular abnormalities. However,these animals showed a significant diminution of cellular proliferation and a reduction of testicular transferrin *** addition,pituitary-gonadal axis was altered,with significant higher levels of FSH(P<0.001 vscontrols)and increased levels of LH in untreated cirrhotic ***,IGF-1 treatment normalized testicular transferrin expression and cellular proliferation and reduced serum levels of LH(P=ns vs controls,and P<0.01 vs untreated cirrhotic group). CONCLUSION:The testicular barrier is altered from an early stage of cirrhosis,shown by a reduction of transferrin expression in Sertoli cells,a diminished cellular proliferation and an altered gonadal *** treatment with IGF-1 could be also useful in this initial stage of testicular disorder associated with compensated cirrhosis.

关键词： Animals Atrophy Carbon Tetrachloride Estrogens Follicle Stimulating Hormone Hypogonadism Insulin-Like Growth Factor I Liver Cirrhosis Luteinizing Hormone Male Pituitary Gland Rats Rats, Wistar Research Support, Non-U.S. Gov't Sertoli Cells Testis Testosterone Transferrin

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Rheological and tribological approaches as a tool for the development of sustainable lubricating greases based on nano-montmorillonite and castor oil

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Friction 2021年第2期9卷 415-428页

作者： Jose enrique MARTÍN-ALFONSO María Jose MARTÍN-ALFONSO Concepción VALENCIA María Teresa CUBERES Department of Chemical Engineering and Materials Science Campus de“El Carmen”University of HuelvaChemical Product and Process Technology Research Center(Pro2TecS)Huelva 21071Spain Department of Applied Mechanics and Project Engineering University of Castilla-La ManchaAlmadén 13400Spain

This study investigates the development of novel montmorillonite/castor oil blends to formulate sustainable lubricating greases to promote the replacement of petrochemicals industry-derived materials by substances obtained from renewable ***,the effect of the thickener concentration on the rheological,chemical,thermal,tribological properties,and atomic force microscopy(AFM)microstructure of these systems were *** results showed that the C20A nanoclay content could be used to modulate the viscosity values,the linear viscoelastic functions,and tribological properties of these montmorillonite *** general,these gel-like dispersions exhibited remarkable lubricant properties;the samples showed values of the friction coefficient and wear scars similar or lower than those obtained with model bentonite grease.

关键词： lubricating greases nanoclay vegetable oil rheology tribology

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Effect of snow on mountain river regimes： an example from the Pyrenees

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Frontiers of Earth Science 2017年第3期11卷 515-530页

作者： Alba SANMIGUEL-VALLELADO enrique MORAN-TEJEDA Esteban ALONSO-gonzAlez Juan Ignacio LOPEZ-MORENO Pyrenean Institute of Ecology CSIC (Spanish Research Council) Zaragoza Spain Department of Geography University of the Balearic Islands Palma de Mallorca Spain

The purpose of this study was to characterize mountain river regimes in the Spanish Pyrenees and to assess the importance of snow accumulation and snowmelt on the timing of river flows. Daily streamflow data from 9 gauging stations in the Pyrenees were used to characterize river regimes. These data were analyzed by hydrological indices, with a focus on periods when snow accumulation and snowmelt occurred. These results were combined with data on Snow Water Equivalent （SWE）（from measure- ments of depth and density of snow in the main river basins and also simulated by a process-based hydrological model）, snowmelting （simulated by a process-based hydrological model）, precipitation （from observations）, and temperature （from observations）. Longitude. and elevation gradients in the Pyrenees explain the transition of river regimes from those that mostly had low nival signals （in the west and at low elevations） to those that mostly had high nival signals （low winter runoff and late spring peakflow, in the east and at high elevations）. Although trend analyses indicated no statistically signifi- cant changes, there was a trend of decreased nival signal over time in most of the analyzed rivers. Our results also demonstrated that snow processes cannot explain all of the interannual variability of river regimes, because the temporal distribution of liquid precipitation and tempera- ture play key roles in hydrography.

关键词： river regime precipitation snow indices,Spanish Pyrenees streamflow

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Apaf1 inhibition promotes cell recovery From apoptosis

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Protein & Cell 2015年第11期6卷 833-843页

作者： Anna Gortat Monica Sancho Laura Mondragon Angel Messeguer enrique Perez-Paya Mar Orzaez Laboratory of Peptide and Protein Chemistry Centro de Investigaci6n Principe Felipe 46012 Valencia Spain Department of Chemical and Biomolecular Nanotechnology Instituto Quimica Avanzada de CataluSa (CSIC) 08034 Barcelona Spain Instituto de Biomedicina de Valencia IBV-CSIC 46010 Valencia Spain

The protein apoptoUc protease activating factor I （Apafl） is the central component of the apoptosome, a multiprotein complex that activates procaspase-9 after cytochrome c release from the mitochondria in the intrinsic pathway of apoptosis. We have developed a vital method that allows fluorescence-activated cell sorting of cells at different stages of the apoptotic pathway and demonstrated that upon pharmacological inhibition of Apafl, cells recover from doxorubicinor hypoxia-induced early apoptosis to normal healthy cell. Inhibiting Apafl not only prevents procaspase-9 activation but delays massive mitochondrial damage allowing cell recovery.

关键词： Apaf1 Apaf1 inhibitors apoptosis,apoptosome autophagy cell recovery

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Interpolation of Vector Measures

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Acta Mathematica Sinica,English Series 2011年第1期27卷 119-134页

作者： Ricardo del CAMPO Antonio FERNANDEZ Fernando MAYORAL Francisco NARANJO enrique A. SANCHEZ-PEREZ Dpto. Matemdtica Aplicada I Universidad de SevillaEUITA Ctra. de Utrera Kin. 1 41013 Sevilla Spain Dpto. Matemdtica Aplicada II Universidad de Sevilla Escuela Tdcnica Superior de Ingenieros Camino de los Descubrimientos s/n 41092 Sevilla Spain Instituto Universitario de Matemdtica Pura y Aplicada Universidad Politdcnica de Valencia Camino de Vera s/n 46022 Valencia Spain

Let （Ω, ∑） be a measurable space and mo ： E→ Xo and m1 ： E → X1 be positive vector measures with values in the Banach KSthe function spaces Xo and X1. If 0 〈 a 〈 1, we define a X01-ax1a new vector measure [m0, m]a with values in the Calderdn lattice interpolation space and we analyze the space of integrable functions with respect to measure [m0, m1]a in order to prove suitable extensions of the classical Stein Weiss formulas that hold for the complex interpolation of LP-spaces. Since each p-convex order continuous Kothe function space with weak order unit can be represented as a space of p-integrable functions with respect to a vector measure, we provide in this way a technique to obtain representations of the corresponding complex interpolation spaces. As applications, we provide a Riesz-Thorin theorem for spaces of p-integrable functions with respect to vector measures and a formula for representing the interpolation of the injective tensor product of such spaces.

关键词： Interpolation Banach function space vector measure

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Puma （Puma concolor） epididymal sperm morphometry

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Asian Journal of Andrology 2016年第6期18卷 879-881页

作者： Hernan Cucho Virgilio Alarcon Cesar Ordonez enrique Ampuero Aydee Meza Caries Solere Zootechny School National University of San Atonio Abad del Cusco Postal code 921 Cusco Peru Functional Biology and Physical Anthropology Department University of Valencia C/. Dr Moliner 50 46100 Burjassot Valencia Spain Proiser R+D S.L. Scientific Park of the University of Valencia 46980 Paterna Spain

The Andean puma （Puma concolor） has not been widely studied, particularly in reference to its semen characteristics. The aim of the present study was to define the morphometry of puma sperm heads and classify their subpopulations by cluster analysis. Samples were recovered postmortem from two epididymides from one animal and prepared for morphological observation after staining with the Hemacolor kit. Morphometric data were obtained from 581 spermatozoa using a CASA-Morph system, rendering 13 morphometric parameters. The principal component （PC） analysis was performed followed by cluster analysis for the establishment of subpopulations. Two PC components were obtained, the first related to size and the second to shape. Three subpopulations were observed, corresponding to elongated and intermediate-size sperm heads and acrosomes, to large heads with large acrosomes, and to small heads with short acrosomes. In conclusion, puma spermatozoa showed no uniform sperm morphology but three clear subpopulations. These results should be used for future work in the establishment of an adequate germplasm bank of this species.

关键词： principal component analysis puma sperm morphometry subpopulation wild animal

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Nature and evolution of the lower crust under central Spain:Inferences from granulite xenoliths(Calatrava Volcanic Field-Spanish central system)

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Geoscience Frontiers 2023年第3期14卷 10-32页

作者： David Orejana Carlos Villaseca Marlina A.Elburg enrique Merino-Martínez Javier García Serrano Departamento de Mineralogía y Petrología Universidad Complutense de MadridSpain Departamento de Dinámica Terrestre y Observación de la Tierra Instituto de Geociencias IGEO(UCMCSIC)MadridSpain Department of Geology University of JohannesburgSouth Africa Instituto Geológico y Minero de España–Consejo Superior de Investigaciones Científicas CN IGME–CSIC

So far,the nature and evolution of the lower crust under central Spain have been constrained mainly on the basis of a heterogeneous suite of granulite xenoliths from the Spanish Central System(SCS).In recent years,ultramafic volcanics from the Calatrava Volcanic Field(CVF)have also provided deep-seated crustal xenoliths which have not been studied in *** data,combining mineral,whole-rock and isotopic geochemistry with U–Pb–Hf isotope ratios in zircons from the CVF and SCS xenoliths,highlight the felsic composition of the lower crust under central Iberia.A number of the Calatrava xenoliths represents Variscan igneous protoliths,which are a minor population in the SCS,and were likely formed by crystallisation of intermediate and felsic melts in the lower crust during the Variscan orogeny(leucodiorite protolith age of 314±3 Ma and leucogranite protolith age of 308±2.5 Ma).U–Pb data of metamorphic zircons show that granulite-facies metamorphism mainly occurred from 299 to 285 Ma in both *** ages are slightly younger than those of granitic intrusions that could be genetically related to the granulitic residue,which points to a main role of U–Pb isotope resetting in lower crustal zircons during HT or UHT *** zircon U–Pb–Hf isotopic ratios support the idea that the lower crust in central Iberia consists mainly of Ordovician–Neoproterozoic metaigneous and metasedimentary rocks associated with the Cadomian continental arc of northern *** rocks provide evidence of mixing between juvenile magmas and an enriched crustal component,ultimately extracted from an Eburnean *** more evolved components present in detrital zircons are likely related to recycling of Archean crust derived from North Africa cratonic terranes.

关键词： Granulite xenoliths U-Pb geochronology Lu-Hf isotopes Calatrava Volcanic Field Spanish central system

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In vivo optical quality of posterior-chamber phakic implantable collamer lenses with a central port

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Eye and Vision 2021年第5期8卷 295-302页

作者： Robert Montés-Micó Francisco Pastor-Pascual enrique Artiaga-Elordi Ramón Ruiz-Mesa Pedro Tañá-Rivero Optics and Optometry&Vision Sciences Department University of Valenciac/o Dr Moliner 5046100 ValenciaSpain Oftalvist Clinic ValenciaSpain

Background:The aim of this review is to summarize the optical quality results in patients following the implantation of the V4c implantable collamer lens with a central port(ICL,STAAR Surgical Inc.).Main text:A literature search in several databases was carried out to identify those publications,both prospective,retrospective and/or comparative with other refractive surgery procedures,reporting optical outcomes of patients who were implanted with the V4c ICL model.A total of 17 clinical studies published between 2012 and 2021 were included in this review.A detailed analysis of the available data was performed including number of eyes,follow-up and preoperative spherical ***,the review focused on several optical parameters including higher-order aberrations(HOAs),modulation transfer function(MTF)cut-off frequency and Strehl *** review encompassed a total of 817 eyes measured using different optical devices based on Hartmann-Shack,retinal image quality measurement and ray-tracing technologies at different ***:The outcomes found in this review lead us to conclude that the ICL V4c model provides good optical quality,by means of different metrics,when implanted.

关键词： Implantable collamer lens Phakic Optical quality Higher order aberrations Modulation transfer function

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