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Corrosion Protection of 5083 AA in SalineWater by Polyacrylonitrile Nanofibers

Journal of Renewable Materials 2021年第11期9卷 1927-1939页

作者： enas H.Ali Juman A.Naser Zainab W.Ahmed Taki A.Himdan Department of Chemistry College of Education for Pure Science-Ibn Al-HaithamUniversity of BaghdadBaghdadIraq

Polymeric nanofibers are a promising technology to protect the metal surfaces from *** the literature search,the use of polyacrylonitrile nanofibres(PANNFs)as a corrosion inhibitor coating for aluminum alloys has not been *** work includes the development of a new,lightweight,high surface area and efficient coating of PANNFs that produced using electrospinning process to resist the corrosion of aluminum alloys(AA5083)which immersed in 0.6 M NaCl at alkaline medium(pH=12)and acidic medium(pH=1)at a range of temperatures(293–323)*** PANNFs coating was successfully deposited on AA 5083 specimens,where these samples were considered as a collector electrode in the electrospinning *** corrosion experiments of the aluminum alloys coated with PANNFs before and after immersion in both corrosive mediums were investigated using cyclic potential polarization(CPP).The results confirmed that the PANNFs coating was able to protect the surface of the aluminum specimens from corrosion,by reducing the corrosion current and increasing the surface polarization resistance,thus reducing the corrosion *** protection efficiency was found in the alkaline medium 98.8%while in the acidic medium 83.3%.So,it was in both mediums decreased with the increase in *** shape,distribution and size of the polymeric nanofibers that formed the coating were also examined using field emission scanning electron microscopy(FE-SEM)and the percentages of the structural components of these fibers were detected using the X-ray dispersion spectroscopy(EDS).The surface of aluminum specimens was completely covered by *** electrospun nanofibers have worn out and lined up spacing after immersion in the corrosive *** diameters average of PANNFs was found to be about 200 and 150 nm before and after immersion,respectively.

关键词： Corrosion protection nanofibers polyacrylonitrile aluminum alloy saline medium protection efficiency

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Preparation and Spectroscopic of Vanadyl（Ⅱ） Vitamin D3 Amino Acid Mixed Complexes as Insulin Mimetic Drug

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光谱学与光谱分析 2019年第7期39卷 2316-2324页

作者： enas Aljuhani Amnah M.A.Alsuhaibani A.M.El-Di damony N.Hassan Sameh Abo Taleb Moamen S.Refat Department of Chemistry Faculty of Applied ScienceUmm Al-Qura UniversityMakkahP.O.9168 Zip Code 21955Saudi Arabia Nutrition and Food Sciences Dept. Home Economic CollegePrincess Nourah Bint Abdulrahman UniversityRiyadhSaudi Arabia Department of Chemistry Faculty of ScienceZagazig UniversityEgypt Department of Chemistry Faculty of SciencePort SaidPort Said UniversityEgypt Chemistry Department Faculty of ScienceTaif UniversityP.O.Box 888Al-HawiahTaif 21974Saudi Arabia

A new six intraperitoneal injection insulin-mimetic vanadyl(Ⅱ) compounds [(VD3^-1)(VO^+2)(AAn^-1)](where(n=1~6);AA1=isoleucine, AA2=threonine, AA3=proline, AA4=phenylalanine, AA5=lysine and AA6=glutamine) were synthesized by the chemical reactions between vitamin D3(VD3), VOSO4 and amino acids(AAn) with equal molar ratio 1∶1∶1 in neutralized media. The structures of these complexes were elucidated by spectroscopic methods like, infrared and solid reflectance spectroscopes. Magnetic moments and electronic spectra reveal square pyramid geometrical structure of the complexes. The infrared spectra assignments of these complexes revealed that the chelation towards vanadyl(Ⅳ) ions existed via deprotonation of the hydroxyl group of VD3 drug ligand and so amino acids act as bidentate ligand via N-amino and O-carboxylate groups. The anti-diabetic efficiency of these complexes were evaluated against streptozotocin induced diabetic male albino rats.

关键词： Insulin alternative Diabetes Drug VO^2+ ion Vitamin D3 Amino acid Spectroscopic

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Synchronization Phenomena Investigation of a New Nonlinear Dynamical System 4D by Gardano’s and Lyapunov’s Methods

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Computers, Materials & Continua 2021年第3期66卷 3311-3327页

作者： Abdulsattar Abdullah Hamad Ahmed S.Al-Obeidi enas H.Al-Taiy Osamah Ibrahim Khalaf Dac-Nhuong Le School of Mathematics Madurai Kamaraj UniversityMadurai625021India Specialty of Mathematics Gifted School of NinevehMosulIraq Al-Nahrain University Baghdad70030Iraq Institute of Research and Development Duy Tan UniversityDanang550000Vietnam Faculty of Information Technology Duy Tan UniversityDanang550000Vietnam

Synchronization is one of the most important characteristics of dynamic *** this paper,the authors obtained results for the nonlinear systems controller for the custom Synchronization of two 4D *** findings have allowed authors to develop two analytical approaches using the second Lyapunov(Lyp)method and the *** the Gardano method does not involve the development of special positive Lyp functions,it is very efficient and convenient to achieve excessive systemSYCR *** is overcome by using Gardano and overcoming some problems in *** we get a great investigation into the convergence of error dynamics,the authors in this paper are interested in giving numerical simulations of the proposed model to clarify the results and check them,an important aspect that will be studied is Synchronization Complete hybrid SYCR and anti-Synchronization,by making use of the Lyapunov expansion analysis,a proposed control method is developed to determine the *** basic idea in the proposed way is to receive the evolution of between two ***,the present model has been applied and showing in a new attractor,and the obtained results are compared with other approximate results,and the nearly good coincidence was obtained.

关键词： Chaos Lu model anti-synchronization hybrid synchronization Gardano’s method nonlinear dynamical system

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CDYL1 fosters double-strand break-induced transcription silencing and promotes homology-directed repair

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Journal of Molecular Cell Biology 2018年第4期10卷 341-357页

作者： enas R. Abu-Zhayia Samah W. Awwad Bella M. Ben-Oz Hanan Khoury-Haddad Nabieh Ayoub Department of Biology Technion-Israel Institute of Technology Haifa 3200003 Israel

Cells have evolved DNA damage response (DDR) to repair DNA lesions and thus preserving genomic stability and impeding carcinogenesis. DNA damage induction is accompanied by transient transcription repression. Here, we describe a previously unrecognized role of chromodomain Y-like (CDYL1) protein in fortifying double-strand break (DSB)-induced transcription repression and repair. We showed that CDYL1 is rapidly recruited to damaged euchromatic regions in a poly (ADP-ribose) polymerase 1 (PARP1)-dependent, but ataxia telangiectasia mutated (ATM)-independent, manner. While the C-terminal region, containing the enoyl-CoA hydratase like (ECH) domain, of CDYL1 binds to poly (ADP-ribose) (PAR) moieties and mediates CDYL1 accumulation at DNA damage sites, the chromodomain and histone H3 trimethylated on lysine 9 (H3K9me3) mark are dispensable for its recruitment. Furthermore, CDYL1 promotes the recruitment of enhancer of zeste homolog 2 (EZH2), stimulates local increase of the repressive methyl mark H3K27me3, and promotes transcription silencing at DSB sites. In addition, following DNA damage induction, CDYL1 depletion causes persistent G2/M arrest and alters H2AX and replication protein A (RPA2) phosphorylation. Remarkably, the ‘traffic-light reporter’ system revealed that CDYL1 mainly promotes homology-directed repair (HDR) of DSBsin vivo. Consequently, CDYL1-knockout cells display synthetic lethality with the chemotherapeutic agent, cisplatin. Altogether, our findings identify CDYL1 as a new component of the DDR and suggest that the HDR-defective ‘BRCAness’ phenotype of CDYL1-deficient cells could be exploited for eradicating cancer cells harboring CDYL1 mutations.

关键词：修理裂缝海滨自动数据处理 poly DNA 终端区域 vivo

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Bio-Fabrication of Silver Nanoparticles Using Catha edulis Extract: Procedure Optimization and Antimicrobial Efficacy Encountering Antibiotic-Resistant Pathogens

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Advances in Nanoparticles 2022年第2期11卷 31-54页

作者： Abdulqawi A. Numan Mashhour Ahmed Mansour S. A. Galil Mohyeddine Al-Qubati Ayman A. Raweh enas A. Helmi Department of Chemistry Faculty of Applied Sciences Taiz University Taiz Yemen Department of Pharmacy Faculty of Medical Sciences Al-Janad University for Science and Technology Taiz Yemen. Department of Pharmaceutical Chemistry and Natural Products University of Science and Technology (UST) Sana’a Yemen Central for Research and Pharmaceutical Studies (CRPS) University of Science and Technology (UST) Sana’a Yemen Department of Mechatronics Faculty of Engineering and Information Technology Al-Janad University for Science and Technology Taiz Yemen Department of Physics Faculty of Applied Sciences Taiz University Taiz Yemen Department of Microbiology Faculty of Applied Sciences Taiz University Taiz Yemen Department of Clinical Laboratory Faculty of Medical Sciences Al-Janad University for Science and Technology Taiz Yemen

The current study aimed to optimize a green synthesis procedure for fabricating biogenic silver nanoparticles (AgNPs) using an aqueous extract of Catha edulis (Qat;khat) leaves. The final product was characterized using various analytical techniques. Parameters’ optimization including pH, contact time, temperature, and amount of leaf extract were carried out. AgNPs formation was confirmed by UV-vis spectra at 403 nm, FT-IR, and XRD peaks. FTIR spectra showed the presence of various biochemical metabolites which played a critical role in the bio-reduction, capping, and stabilization of AgNPs. The biogenic AgNPs were spherical in shape with an average size between 27 and 32 nm as estimated from XRD and SEM images. Biogenic AgNPs showed significant activities against sensitive and multi-drug resistance Escherichia coli and Staphylococcus aureus strains. In addition, the experimental results proved that AgNPs have higher efficacy than antifungal drugs that are commonly used to treat Candida albicans oral infections.

关键词： Silver Nanoparticles Biosynthesis Catha edulis Candida albicans Antibacterial Activity

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Performance Comparison of Various Machine Learning Approaches to Identify the Best One in Predicting Heart Disease

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Journal of Computer and Communications 2022年第2期10卷 1-18页

作者： enas M. Abd Allah Doaa E. El-Matary Esraa M. Eid Adly S. Tag El Dien Electronics and Communications Department Al-Safwa High Institute of Engineering Qalyubia Egypt Electrical Engineering Department Faculty of Engineering at Shoubra Benha University Cairo Egypt

Nowadays, machine learning is growing fast to be more popular in the world, especially in the healthcare field. Heart diseases are one of the most fatal diseases, and an early prediction of such disease is a vital task for many medical professionals to save their patient’s life. The main contribution of this research is to provide a comparative analysis of different machine learning models to reach the most supporting decision for diagnosing heart disease with better accuracy as compared to existing models. Five models namely, K-Nearest Neighbor (KNN), Logistic Regression (LR), Random Forest (RF), Support Vector Machine (SVM), and Extreme Gradient Boost (XGB), have been introduced for this purpose. Their performance has been tested and compared considering different metrics for precise evaluation. The comparative study has proven that the XGB is the most suitable model due to its superior prediction capability to other models with an accuracy of 91.6% and 100% on two different heart ailments datasets, respectively. Both datasets were acquired from the heart diseases repositories where dataset_1 was taken from the University of California, Irvine (UCI) and dataset_2 was from Kaggle.

关键词： Machine Learning Healthcare Heart Disease Prediction

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Changing dietary n-6:n-3 ratio using different oil sources affects performance,behavior,cytokines mRNA expression and meat fatty acid profile of broiler chickens

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Animal Nutrition 2018年第1期4卷 -页

作者： Doaa Ibrahim Rania El-Sayed Safaa I.Khater enas N.Said Shefaa A.M.El-Mandrawy Department of Nutrition and Clinical Nutrition Faculty of Veterinary MedicineZagazig University Department of Biochemistry Faculty of Veterinary MedicineZagazig University Department of Veterinary Public Health Faculty of Veterinary MedicineZagazig University Department of Clinical Pathology Faculty of Veterinary MedicineZagazig University

Typical formulated broiler diets are deficient in n-3 poly-unsaturated fatty acids(PUFA) due to widening n-6:n-3 PUFA ratio which could greatly affect performance,immune system of birds and,more importantly,meat *** study was conducted to evaluate the effect of modifying dietary n-6:n-3 PUFA ratio from plant and animal oil sources on performance,behavior,cytokine m RNA expression,antioxidative status and meat fatty acid profile of broiler ***(n=420) were fed 7 diets enriched with different dietary oil sources and ratios as follows: sunflower oil in control diet(C); fish oil(FO); 1:1 ratio of sunflower oil to FO(C1 FO1); 3:1 ratio of sunflower oil to fish oil(C3 FO1); linseed oil(LO); 1:1 ratio of sunflower oil to linseed oil(C1 LO1); 3:1 ratio of sunflower oil to linseed oil(C3 LO1),resulting in dietary n-6:n-3 ratios of approximately 40:1,1.5:1,4:1,8:1,1:1,2.5:1 and 5:1,*** best final body weight,feed conversion ratio as well as protein efficiency ratio of broilers were recorded in the C1 FO1 and C1 LO1 *** with the control group,the dressing percentage and breast and thigh yield were highest in the C1 FO1 and C1 LO1 *** the dietary n-6:n-3 ratio increased(P < 0.05) n-3 PUFA content of breast ***,the breast meat contents of eicosapentaenoic acid and docosahexaenoic acid increased(P < 0.05) with increasing dietary FO whereas a-linolenic acid content was higher with LO ***,enriching the diets with n-3 PUFA from FO and LO clearly decreased(P < 0.05) serum total cholesterol,triglycerides and very low-density lipoproteins and enhanced antioxidative *** feeding frequency was decreased(P < 0.05) in the C1 FO1 and C1 LO1 ***,n-3 PUFA-enriched diets enhanced the frequency of preening,wing flapping and *** oil source addition,compared to plant oil,to broiler diets enhanced the relative m RNA expression of interferon gamma,interleukin-1 beta,interleukin-2 and

关键词： Broiler n-6:n-3 PUFA ratio Performance Antioxidant status Meat Immunity

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STW 5 is effective against nonsteroidal anti-inflammatory drugs induced gastro-duodenal lesions in rats

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World Journal of Gastroenterology 2019年第39期25卷 5926-5935页

作者： Mohamed T Khayyal Walaa Wadie enas A Abd El-Haleim Kawkab A Ahmed Olaf Kelber Ramy M Ammar Heba Abdel-Aziz Department of Pharmacology Faculty of PharmacyCairo UniversityCairo 11562Egypt Department of Pathology Faculty of Veterinary MedicineCairo UniversityCairo 12211Egypt Steigerwald Arzneimittelwerk GmbH Bayer Consumer HealthDarmstadt 64295Germany Department of Pharmacology Faculty of PharmacyKafrelsheikh UniversityKafrelsheikh 33511Egypt

BACKGROUND Proton pump inhibitors are often used to prevent gastro-intestinal lesions induced by nonsteroidal anti-inflammatory ***,they are not always effective against both gastric and duodenal lesions and their use is not devoid of side *** To explore the mechanisms mediating the clinical efficacy of STW 5 in gastroduodenal lesions induced by nonsteroidal anti-inflammatory drugs(NSAIDs),exemplified here by diclofenac,in a comparison to *** Gastro-duodenal lesions were induced in rats by oral administration of diclofenac(5 mg/kg)for 6 successive *** group was given concurrently STW 5(5 mL/kg)while another was given omeprazole(20 mg/kg).A day later,animals were sacrificed,stomach and duodenum excised and divided into 2 segments:One for histological examination and one for measuring inflammatory mediators(tumor necrosis factorα,interleukins-1βand 10),oxidative stress enzyme(heme oxygenase-1)and apoptosis regulator(B-cell lymphoma 2).RESULTS Diclofenac caused overt histological damage in both tissues,associated with parallel changes in all parameters *** 5 and omeprazole effectively prevented these changes,but STW 5 superseded omeprazole in protecting against histological damage,particularly in the *** The findings support the therapeutic usefulness of STW 5 and its superiority over omeprazole as adjuvant therapy to NSAIDs to protect against their possible gastro-duodenal side effects.

关键词： Diclofenac STW 5 Omeprazole Gastro-intestinal lesions Inflammation

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Progress in plant-based bioelectrochemical systems and their connection with sustainable development goals

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Carbon Resources Conversion 2021年第1期4卷 169-183页

作者： enas Taha Sayed Mohammad Ali Abdelkareem Khaled Obaideen Khaled Elsaid Tabbi Wilberforce Hussein M.Maghrabie A.G.Olabi Center for Advanced Materials Research University of SharjahPO Box 27272SharjahUnited Arab Emirates Chemical Engineering Department Minia UniversityElminiaEgypt Dept.of Sustainable and Renewable Energy Engineering University of SharjahP.O.Box 27272SharjahUnited Arab Emirates Chemical Engineering Department Texas A&M UniversityCollege StationTX 77843-3122TXUSA Mechanical Engineering and Design Aston UniversitySchool of Engineering and Applied ScienceAston TriangleBirmingham B47ETUK Department of Mechanical Engineering Faculty of EngineeringSouth Valley UniversityQena 83521Egypt

Living organisms’energy conversion is considered as an essential and sustainable green energy source and future bio-hybrid ***,plants were used after harvesting as biomass in bio-fermentation as an energy *** bio-electrochemical systems,microorganisms work with plants to generate electricity,hydrogen,or *** work discusses the simultaneous pollutant removal and electricity generation in plant-based bio-electrochemical systems(P-BES).Factors affecting the P-BES performance and the removal efficiencies of the different organic and inorganic pollutants were ***,the plant-based bioelectrochemical systems’role in achieving the sustainable development goals(SDGs)was *** SDGs contribution of plant-based bioelectrochemical systems were presented and discussed to evaluate such systems’ability to achieve the three pillars of sustainable development,i.e.,economic,environmental,and social.

关键词： Plant Bioelectrochemical systems Sustainable development goals,pollutant removal Power generation

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伊维菌素抑制NLRP3炎症小体可改善博来霉素诱导的肺纤维化（英文）

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2023年第8期 723-737页

作者： Mai A.ABD-ELMAWLA Heba R.GHAIAD enas S.GAD Kawkab A.AHMED Maha ABDELMONEM 埃及开罗大学药学院生物化学系费萨尔国王大学药学院药学系埃及西奈大学药学院药理毒理学系埃及开罗大学兽医学院病理学系

伊维菌素是美国食品药品监督管理局（FDA）批准的抗寄生虫剂，具有抗病毒和抗炎特性。尽管最近有研究表明伊维菌素在呼吸系统损伤中可能具有抗炎活性，但其对肺纤维化（PF）的潜在影响尚未得到验证。本研究旨在探讨伊维菌素（0.6 mg/kg... 详细信息

伊维菌素是美国食品药品监督管理局（FDA）批准的抗寄生虫剂，具有抗病毒和抗炎特性。尽管最近有研究表明伊维菌素在呼吸系统损伤中可能具有抗炎活性，但其对肺纤维化（PF）的潜在影响尚未得到验证。本研究旨在探讨伊维菌素（0.6 mg/kg）在PF大鼠模型中减轻博来霉素诱导的生化紊乱和组织学变化的效果。这可用于验证伊维菌素作为治疗特发性PF在临床上的效用。在本研究中，伊维菌素减轻了博来霉素诱发的肺损伤，表现为炎症细胞浸润减少以及炎症和纤维化评分降低。值得注意的是，伊维菌素减少了胶原纤维的沉积并抑制了转化生长因子-β1(TGF-β1)和纤连蛋白的表达，突显了其抗纤维化活性。本研究首次揭示伊维菌素可以抑制NOD样受体家族含吡啶结构域蛋白3(NLRP3)炎症小体，表现为NLRP3和含有半胱天冬酶募集结构域的凋亡相关斑点样蛋白（ASC）基因的表达减少，以及白细胞介素-1β(IL-1β)水平的下降。此外，伊维菌素抑制细胞内核因子-κB(NF-κB)和缺氧诱导因子-1α(HIF-1α)蛋白的表达，同时降低氧化应激和凋亡标志物的水平。本研究表明，伊维菌素可以改善博来霉素引起的肺部炎症和纤维化，并且部分功能是通过下调TGF-β1和纤连蛋白以及通过调节HIF-1α和NF-κB的表达抑制NLRP3炎性小体来介导的。

关键词：气管内滴注免疫组化转化生长因子-β1(TGF-β1) 核转录因子-κB(NF-κB) 肺纤维化

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