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Interconnections between diabetic corneal neuropathy and diabetic retinopathy:diagnostic and therapeutic implications

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Neural Regeneration Research 2025年第8期20卷 2169-2180页

作者： Mingyi yu Faith Teo en Ning Chang Liu yu-Chi Liu Tissue engineering and Stem Cell Group Singapore Eye Research InstituteSingapore Yong Loo Lin School of Medicine National University of SingaporeSingapore Department of Cornea and External Eye Disease Singapore National Eye CenterSingapore Ophthalmology and Visual Sciences Academic Clinical Program Duke-NUS Medical SchoolSingapore

Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes *** corneal neuropathy refers to the progressive damage of corneal *** retinopathy has traditionally been considered as damage to the retinal ***,growing evidence suggests that diabetic retinopathy is a complex neurovascular disorder resulting from dysfunction of the neurovascular unit,which includes both the retinal vascular structures and neural *** retinopathy is one of the leading causes of blindness and is frequently screened for as part of diabetic ocular ***,diabetic corneal neuropathy is commonly overlooked and underdiagnosed,leading to severe ocular surface *** studies have found that these two conditions tend to occur together,and they share similarities in their pathogenesis pathways,being triggered by a status of chronic *** review aims to discuss the interconnection between diabetic corneal neuropathy and diabetic retinopathy,whether diabetic corneal neuropathy precedes diabetic retinopathy,as well as the relation between the stage of diabetic retinopathy and the severity of corneal *** also endeavor to explore the relevance of a corneal screening in diabetic eyes and the possibility of using corneal nerve measurements to monitor the progression of diabetic retinopathy.

关键词： cornea corneal nerves diabetes diabetic corneal neuropathy diabetic retinopathy retina

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英语国家经济研究性论文摘要的概念意义

重庆工商大学学报（社会科学版） 2008年第3期25卷 146-150页

作者：于恩江广东医学院广东东莞523808

国内一些经济研究性论文的英语摘要,或受本民族文化和语言的影响,或由于英语写作水平不高,或对论文摘要文体的特点了解得不够,往往写得既不符合英语文法,也不符合经济研究性论文摘要的要求,严重影响读者,尤其是国外读者,阅读论文的兴趣... 详细信息

国内一些经济研究性论文的英语摘要,或受本民族文化和语言的影响,或由于英语写作水平不高,或对论文摘要文体的特点了解得不够,往往写得既不符合英语文法,也不符合经济研究性论文摘要的要求,严重影响读者,尤其是国外读者,阅读论文的兴趣和对论文的准确理解,进而妨碍了经济研究的国际交流。很多规范的英语国家经济性论文的摘要可以作为中国人撰写经济性研究论文英文摘要的范本。

关键词：英语国家经济研究性论文摘要功能语篇分析概念意义语场

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英语国家经济研究性论文摘要的人际意义

辽宁教育行政学院学报 2008年第9期25卷 117-120页

作者：于恩江广东医学院广东东莞523808

目前,国内外对英语摘要的研究,有的归纳其一般特征,有的从语言学角度研究其语篇特征,也有的将相关学科的英语摘要与其对应的其他语言的摘要进行对比性研究。但是,文献表明,迄今尚没有人用功能语篇分析的方法研究英语国家的经济研究性论... 详细信息

目前,国内外对英语摘要的研究,有的归纳其一般特征,有的从语言学角度研究其语篇特征,也有的将相关学科的英语摘要与其对应的其他语言的摘要进行对比性研究。但是,文献表明,迄今尚没有人用功能语篇分析的方法研究英语国家的经济研究性论文的英语摘要的人际意义。

关键词：英语国家经济研究性论文摘要人际意义

锌冶炼区菜地土壤和蔬菜重金属污染状况及风险评价

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中国环境科学 2019年第5期39卷 2086-2094页

作者：余志陈凤张军方黄代宽于恩江刘鸿雁贵州大学资源与环境工程学院贵州贵阳550025 贵州省环境科学研究设计院贵州贵阳550081 贵州大学农学院贵州贵阳550025

对黔西北地区某典型锌冶炼区菜地土壤和主要蔬菜进行取样调查,测定了土壤和蔬菜可食用部分Pb、Cd、Zn、Cu、As、Ni 6种重金属的含量,采用单项污染指数和综合污染指数法评价了土壤和蔬菜中重金属的污染状况,并分别采用潜在生态风险指数(... 详细信息

对黔西北地区某典型锌冶炼区菜地土壤和主要蔬菜进行取样调查,测定了土壤和蔬菜可食用部分Pb、Cd、Zn、Cu、As、Ni 6种重金属的含量,采用单项污染指数和综合污染指数法评价了土壤和蔬菜中重金属的污染状况,并分别采用潜在生态风险指数(RI)和目标危险系数法(THQ)评价了菜地土壤重金属污染的潜在生态风险和蔬菜中重金属对成人和青少年儿童的健康风险.结果表明,该区域菜地土壤已受到重金属的重度污染,且以Cd对综合指数的贡献最大,土壤Cd存在极强生态风险,研究区处于轻微、中等、强和很强的生态风险程度的采样点比例分别为2.0%、14.3%、35.7%和48.0%;在所采集的蔬菜样本中,土豆处于重度污染水平,芸豆处于中度污染水平;复合重金属健康风险指数评价结果表明,食用研究区域蔬菜对成人和青少年儿童健康产生负面影响的可能性很大.

关键词：锌冶炼土壤蔬菜重金属污染生态风险健康风险

地质高背景与污染叠加区不同土地利用方式下土壤重金属分布特征

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环境科学 2022年第4期43卷 2094-2103页

作者：王雪雯刘鸿雁顾小凤涂宇于恩江吴攀贵州大学农学院贵阳550025 喀斯特地质资源与环境教育部重点实验室贵阳550025 贵州省农业科学院土壤肥料研究所贵阳550025

黔西北喀斯特地质高背景和历史遗留土法炼锌污染叠加,导致土壤重金属污染严重.为了解不同土地利用方式对土壤重金属分布的影响,选择威宁县某在产锌粉厂小流域为研究区域,共采集表层和剖面土壤样品126件,对农用地、荒地和林地土壤重金属... 详细信息

黔西北喀斯特地质高背景和历史遗留土法炼锌污染叠加,导致土壤重金属污染严重.为了解不同土地利用方式对土壤重金属分布的影响,选择威宁县某在产锌粉厂小流域为研究区域,共采集表层和剖面土壤样品126件,对农用地、荒地和林地土壤重金属(Cd、As、Pb、Cu和Zn)的空间分布、来源和生态风险进行分析和评价.结果表明,研究区表层土壤ω(Cd)、ω(As)、ω(Pb)、ω(Cu)和ω(Zn)平均值为8.14、45.07、263.97、41.36和716.98mg·kg^(-1),是背景值的1.29~12.33倍,除Zn外,土壤重金属表现为:农用地>荒地>林地;从空间分布上看,重金属含量高的土壤集中分布在锌粉厂和矿渣堆放点周边;在土壤剖面上,表层重金属普遍高于底层,荒地分布达显著差异水平,底层土壤重金属均高于背景值,表现出地质高背景的特征.相关分析和主成分分析结果显示,3种土地利用方式下表层土壤的Pb、Zn和As主要受到矿业和交通等人类活动的影响,Cd和Cu污染是地质高背景和人类活动共同作用的结果.土壤重金属Cd的单项生态风险系数最高,达到很强或极强风险,As、Zn、Cu和Pb达轻微或中等风险,研究区综合潜在生态风险指数总体表现为强生态风险,农用地风险强度高,荒地和林地相对较低.在喀斯特地质高背景区,铅锌冶炼对区域土壤重金属分布和累积的影响大于土地利用方式,土壤重金属污染叠加严重,生态风险高,应加强对重金属污染土壤的严格管控.

关键词：地质高背景铅锌冶炼土壤重金属土地利用方式潜在生态风险指数

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薄膜分散法制备姜黄素纳米粒的研究

食品科技 2014年第11期39卷 105-109页

作者：典灵辉林晓于恩江罗京彪华玉广东医学院药学院东莞523808

为了增加姜黄素溶解度和稳定性,采用薄膜分散法制备姜黄素纳米粒;采用粒径测定仪、透射电镜、X-射线衍射(XRD)对其进行表征,采用UV法测定纳米粒的包封率和载药量,采用动态膜透析法考察载药纳米粒的体外释药特性。制备的纳米粒呈球形或... 详细信息

为了增加姜黄素溶解度和稳定性,采用薄膜分散法制备姜黄素纳米粒;采用粒径测定仪、透射电镜、X-射线衍射(XRD)对其进行表征,采用UV法测定纳米粒的包封率和载药量,采用动态膜透析法考察载药纳米粒的体外释药特性。制备的纳米粒呈球形或类球形,平均粒径为(61.52±2.76)nm,平均包封率为(89.95±3.57)%,平均载药量(5.62±1.02)%;XRD结果表明,姜黄素以无定型状态或分子状态包载在纳米粒中;体外释放结果表明姜黄素的纳米粒具有明显缓释作用。该纳米粒制备工艺简单,其粒径、包封率、载药量可控,具有缓释作用。

关键词：姜黄素纳米粒薄膜分散法

Statistical analysis on the validity of the cold plasma approximation for chorus waves based on Van Allen Probe observations and their effects on radiation belt electrons

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Earth and Planetary Physics 2025年第1期9卷 159-170页

作者： AoJun Ren jiang yu Jing Wang ZuZheng Chen XiaoMan Liu Planetary environmental and Astrobiological Research Laboratory(PEARL) School of Atmospheric SciencesSun Yat-sen UniversityZhuhai Guangdong 519000China

Theoretical analysis has demonstrated that the dispersion relation of chorus waves plays an essential role in the resonant interaction and energy transformation between the waves and magnetospheric *** quantitative analyses often simplified the chorus dispersion relation by using the cold plasma ***,the applicability of the cold plasma assumption is doubtful,especially during geomagnetic *** here present a systematic statistical analysis on the validity of the cold plasma dispersion relation of chorus waves based on observations from the Van Allen Probes over the period from 2012 to *** statistical results show that the observed magnetic field intensities deviate substantially from those calculated from the cold plasma dispersion relation and that they become more pronounced with an increase in geomagnetic activity or a decrease in background plasma *** region with large deviations is mainly concentrated in the nightside and expands in both the radial and azimuthal directions as the geomagnetic activity increases or the background plasma density *** addition,the bounce-averaged electron scattering rates are computed by using the observed and cold plasma dispersion relation of chorus *** with usage of the cold plasma dispersion relation,usage of the observed dispersion relation considerably lowers the minimum resonant energy of electrons and lowers the scattering rates of electrons above tens of kiloelectronvolts but enhances those ***,these differences are more pronounced with the enhancement of geomagnetic activity or the decrease in background plasma density.

关键词： chorus waves cold plasma approximation dispersion relations scattering rates

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姜黄素聚合物胶束的制备及体外评价

中国医院药学杂志 2015年第3期35卷 213-216页

作者：林晓典灵辉于恩江张振声广东医学院药学院广东东莞523808

目的:制备姜黄素的Soluplus聚合物胶束,并对其进行体外评价。方法:采用薄膜分散法制备姜黄素聚合物胶束;采用粒径测定仪、透射电镜、X-射线衍射(XRD)对其进行表征;采用紫外分光光度法测定胶束的包封率和载药量;采用动态膜透析法考察载... 详细信息

目的:制备姜黄素的Soluplus聚合物胶束,并对其进行体外评价。方法:采用薄膜分散法制备姜黄素聚合物胶束;采用粒径测定仪、透射电镜、X-射线衍射(XRD)对其进行表征;采用紫外分光光度法测定胶束的包封率和载药量;采用动态膜透析法考察载药胶束的体外释药特性。结果:薄膜分散法制备的胶束呈球形或类球形,平均粒径为(65.54±2.57)nm,平均包封率为(87.73±2.94)%,平均载药量(7.96±2.13)%;XRD结果表明姜黄素以无定型状态或分子状态包载在聚合物胶束中;体外释放结果表明姜黄素的soluplus聚合物胶束具有缓释作用。结论:该胶束制备工艺简单,其粒径、包封率、载药量可控,具有缓释作用。

关键词：姜黄素 Soluplus 聚合物胶束体外评价

Ideal Bi-Based Hybrid Anode Material for Ultrafast Charging of Sodium-Ion Batteries at Extremely Low Temperatures

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NANO-MICRO LETTERS 2025年第1期17卷 1-16页

作者： Bai, Jie Jia, Jian Hui Wang, yu Yang, Chun Cheng jiang, Qing Jilin Univ Key Lab Automobile Mat Sch Mat Sci & Engn Minist Educ Changchun 130022 Peoples R China

Metallic nanoparticles with excellent size controllability and high loading rate are obtained via ultrafast high temperature shock *** Bi/CNRs-15 electrode exhibits an unprecedented rate performance (237.9 mAh g-1 at 2 A g-1) at - 60 degrees C, while the energy density of the full cell can reach to 181.9 Wh kg-1 at - 40 degrees C.A novel strategy of high-rate activation is proposed to obtain high capacity and superior stability at low temperature by creating new active sites for interfacial reaction. Sodium-ion batteries have emerged as competitive substitutes for low-temperature applications due to severe capacity loss and safety concerns of lithium-ion batteries at - 20 degrees C or lower. However, the key capability of ultrafast charging at ultralow temperature for SIBs is rarely reported. Herein, a hybrid of Bi nanoparticles embedded in carbon nanorods is demonstrated as an ideal material to address this issue, which is synthesized via a high temperature shock method. Such a hybrid shows an unprecedented rate performance (237.9 mAh g-1 at 2 A g-1) at - 60 degrees C, outperforming all reported SIB anode materials. Coupled with a Na3V2(PO4)3 cathode, the energy density of the full cell can reach to 181.9 Wh kg-1 at - 40 degrees C. Based on this work, a novel strategy of high-rate activation is proposed to enhance performances of Bi-based materials in cryogenic conditions by creating new active sites for interfacial reaction under large current.

关键词： Bi nanoparticles High temperature shock High-rate activation Ultrafast charging Low-temperature sodium-ion batteries