检索结果-南通市图书馆

Role of Histamine H1 Receptors in Vestibular Nucleus in Motion Sickness

Journal of Otology 2011年第1期6卷 20-25页

作者： HUANG Li-gui WANG en-tong CHen Wei gong Wei-xi Department of Otolaryngology-Head and Neck Surgery Lushan Hospital of PLA Jiujiang 332000 China Department of Otolaryngology-Head and Neck Surgery General Hospital of Air Force Beijing 100142 China

Objectives To investigate the expression of histamine H1 receptors （H1R） in the vestibular nucleus of brainstem in rats and the role of H1R in motion sickness （MS）. Methods A total of 24 healthy Sprague-Dawley rats were divided randomly into four groups （n=6 each） which determined if the animals would receive induction of MS or drug （promethazine） treatment： MS （ - ）/Drug （ - ）; MS（＋）/Drug （ - ）; MS （ - ）/Drug （＋ at 0.25 mg）; and MS （＋）/ Drug（＋）. MS was induced by complex motion stimulation and the conditioned taste aversion was used as a behavioral indicator of MS. The volume of 0.15% sodium saccharin solution （SS） intake within 45 minutes after motion stimulation was measured. H1R in the vestibular nucleus was examined by immunofluorescence staining. The expression of H 1R protein in brainstem tissue at vestibular nucleus level was detected by western blot. Results The mean SS intake volume in the MS （＋）/Drug （ - ） group （8.8 ml） was significantly less than that of the MS （ - ）/Drug （ - ） group （15.1 ml）（P 〈 0.01）. The mean SS intake volume of the MS （-）/Drug （＋） group （14.8 ml） was similar to that of the MS（-）/Drug（-） group. The mean SS intake volume （9.6 ml） of the MS（＋）/Drug（＋） group was more than that of the MS（＋）/Drug（-）group （P〈0.01）, but less than that of the MS（-）/Drug（-） group or MS（-）/Drug（＋） group （P 〈 0.01）. Immunofluorescence staining showed positive expression of H1R in the vestibular nucleus of brainstem and the expression was enhanced by motion stimulation. Western blot analysis showed that H1R protein expressed in the brainstem tissue at vestibular nucleus level and the expression also increased significantly after motion stimulation. The MS-induced increase of H1R was not affected significantly by promethazine. Conclusions H1Rs exist in the vestibular nucleus in rats and H 1R expression is up-regulated by motion stimulation, but not affected by promethazine. The findings indicate that the histaminergic system is involved in MS. Promethazine

关键词： motion sickness histamine H1 receptor vestibular nucleus promethazine rat

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

低品位双重难处理金矿石工艺矿物学及浸金影响因素

引用

东北大学学报（自然科学版） 2008年第12期29卷 1742-1745页

作者：杨洪英巩恩普杨立东北大学材料与冶金学院辽宁沈阳110004 东北大学资源与土木工程学院辽宁沈阳110004

试验所用矿石来自我国云南某金矿,该矿含金2.4 g/t,砷0.97%,碳1.47%.它是典型的低品位含碳双重难处理金矿石,浮选精矿-氰化提金,金浸出率为10.43%;浮选精矿-焙烧-氰化工艺,金浸出率为46.52%,属于极难浸金矿.矿石主要金属矿物为黄铁矿、... 详细信息

试验所用矿石来自我国云南某金矿,该矿含金2.4 g/t,砷0.97%,碳1.47%.它是典型的低品位含碳双重难处理金矿石,浮选精矿-氰化提金,金浸出率为10.43%;浮选精矿-焙烧-氰化工艺,金浸出率为46.52%,属于极难浸金矿.矿石主要金属矿物为黄铁矿、毒砂.脉石矿物主要为石英、绢云母、白云石、方解石、伊利石黏土矿物等.金的赋存状态绝大多数是"不可见金",主要为次显微、超显微的包裹金以及胶体金.金主要包裹于毒砂和黄铁矿晶体中.矿石中金矿物主要为自然金,少为银金矿.矿石金回收率低的原因主要是包裹金,矿石含砷、碳质以及黏土矿物.

关键词：低品位双重难处理金矿石碳质工艺矿物学浸金

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

买方“跳单”行为下房产中介代理合约选择

引用

系统工程理论与实践 2015年第10期35卷 2698-2707页

作者：王晨龚朴上海商学院财经学院上海200235 华中科技大学管理学院武汉430074

依据合约理论的分析框架,研究了面对中国普遍存在的买方"跳单"行为,房产中介应当如何在开放性代理合约和独家代理合约中进行选择.首先通过模型的建立与求解分析了各合约下中介的最优的努力水平,并研究了买方"跳单"概率和卖方房屋售价对... 详细信息

依据合约理论的分析框架,研究了面对中国普遍存在的买方"跳单"行为,房产中介应当如何在开放性代理合约和独家代理合约中进行选择.首先通过模型的建立与求解分析了各合约下中介的最优的努力水平,并研究了买方"跳单"概率和卖方房屋售价对最优决策的影响.然后基于最优决策,对两种合约进行了比较,结果显示中介在独家代理时应实施更高的努力水平;若买方"跳单"概率较小,中介应该选择开放性代理;若买方"跳单"概率较大,中介应对售价较高或较低的房屋采用开放性代理,对售价处在中间水平的房屋采用独家代理.另外,数值实验表明,随着买方"跳单"概率的增加,中介应对更多的房屋采用独家代理合约.而随着独家代理费的升高,在更大的"跳单"概率范围内,中介一定不应该选择独家代理合约.

关键词：房产中介 “跳单”行为开放性代理独家代理合约选择

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

投资者异质信念下可转换债券赎回策略

引用

系统工程理论与实践 2012年第3期32卷 656-663页

作者：龚朴陈睿华中科技大学管理学院武汉430074

可转换债券现有研究模型多建立在投资者理性范式之下,较少考虑投资者异质信念的影响,易造成可转换债券定价偏差,市场上所存在的众多异象如推迟(或提前)赎回至今也未能获得良好的解释.将行为金融理论引入可转换债券定价模型之中,采用投... 详细信息

可转换债券现有研究模型多建立在投资者理性范式之下,较少考虑投资者异质信念的影响,易造成可转换债券定价偏差,市场上所存在的众多异象如推迟(或提前)赎回至今也未能获得良好的解释.将行为金融理论引入可转换债券定价模型之中,采用投资者的后悔厌恶来表征投资者的异质信念,构建了投资者异质信念下可转换债券定价模型,重点探讨了异质信念对可转换债券赎回策略的影响.理论模型及数值实验结果均表明可转换债券发行者的后悔厌恶情绪是可转换债券推迟(或提前)赎回的一个重要原因.

关键词：可转换债券异质信念后悔厌恶行为金融赎回策略

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

In vivo investigation of the role of SfmO2 in saframycin A biosynthesis by structural characterization of the analogue saframycin O

引用

Science China Chemistry 2012年第1期55卷 90-97页

作者： PenG Chao TANG Yu-Min LI Lei DING Wei DenG Wei pu Jin-Yue LIU Wen TANG gong-Li State Key Laboratory of Bio-organic and Natural Products Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of SciencesShanghai 200032China

Saframycin A(SFM-A),a tetrahydroisoquinoline antibiotic isolated from Streptomyces lavendulae,shows potent anti-proliferation activities against a variety of tumor cell lines,and shares the core structure with ecteinascidin 743(ET-743),the anticancer drug for soft-tissue *** of the SFM-A biosynthetic gene cluster revealed three nonribosomal peptide synthetase genes and a series of genes encoding *** investigate the function of sfmO2 gene,encoding a FAD-dependent monooxygenase/hydroxylase,we constructed the gene replacement mutant(△sfmO2) strain *** TL2007 and the corresponding gene complementation mutant strain *** TL2008.A novel compound,SFM-O,was isolated from the △sfmO2 replacement mutant strain and its structure was characterized by comparison to the HRMS and NMR spectra of *** findings indicated that SfmO2 is responsible for the oxidation of ring A in the biosynthetic pathway of SFM-A,and the new compound SFM-O could be considered as an advanced intermediate in the semisynthesis of ET-743.

关键词： saframycin A biosynthesis SfmO2 oxygenase saframycin O

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

广西某锰银矿工艺矿物学及锰的赋存状态

引用

东北大学学报（自然科学版） 2006年第2期27卷 199-202页

作者：杨洪英巩恩普范有静东北大学材料与冶金学院辽宁沈阳110004 东北大学资源与土木工程学院辽宁沈阳110004 东北大学理学院辽宁沈阳110004

对广西某锰银矿进行了工艺矿物学的研究，查明了锰银原矿石矿矿物成分．金属矿物主要为硬锰矿、软锰矿、黄铁矿、赤铁矿和少量毒砂、黄铜矿、闪锌矿．矿石的主要结构是隐晶质结构、胶状结构、显微鳞片结构及砂质结构．主要的构造是脉状... 详细信息

对广西某锰银矿进行了工艺矿物学的研究，查明了锰银原矿石矿矿物成分．金属矿物主要为硬锰矿、软锰矿、黄铁矿、赤铁矿和少量毒砂、黄铜矿、闪锌矿．矿石的主要结构是隐晶质结构、胶状结构、显微鳞片结构及砂质结构．主要的构造是脉状构造、胶状构造、浸染状构造．精矿中银品位是3923g·t^-1，锰的赋存状态是独立的锰矿物，锰矿物是硬锰矿和软锰矿．精矿中硬锰矿在0．152～0．088mm粒级范围内占17％，0．088～0．074mm粒级范围内占38％；〉0．074mm粒级范围占40％；软锰矿在0．152～0．088mm粒级范围内占18％，0．088～0．074mm粒级范围内占35％；〉0．074mm粒级范围占37％．

关键词：锰银矿锰的赋存状态工艺矿物学广西

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ecosystem service valuation of bays in East China Sea and its response to sea reclamation activities

引用

Journal of Geographical Sciences 2020年第7期30卷 1095-1116页

作者： LIU Ruiqing XU Hao LI Jialin pu Ruiliang SUN Chao CAO Luodan JIANG Yimei TIAN Peng WANG Lijia gong Hongbo Donghai Institute Ningbo UniversityNingbo 315211ZhejiangChina Department of Geography&Spatial Information Techniques Ningbo UniversityNingbo 315211ZhejiangChina School of Geosciences University of South FloridaTampaFL 33620-5250USA

Ecosystem service values(ESVs)of bays and their response to sea reclamation are of great practical importance for forming bay eco-compensation policy and extension of blue economic *** on land use information of bays collected during the period of 1990–2015,the spatiotemporal evolution of ESVs of 12 main bays in East China Sea and their response to sea reclamation activities over the past 25 years were quantitatively *** analysis results indicate that ESVs of bays in East China Sea showed a continuous downward trend and the whole ecosystem was continuously degraded,in which the degradation degree of ESV in the southern bays was higher than that in the northern *** zoning of ESVs of bays in East China Sea was remarkable,showing a continuous downward trend from low-value to high-value *** variation of ESVs of each bay was also significant,expanding from a city and from inland to the coast,which suggests that human activities,mainly reclamation,have become main agents for ESV evolution of bays in East China *** of bays have a significant response to sea reclamation,manifested as a significant negative correlation between ESV and reclamation *** correlation in the southern bays was stronger than that in the northern bays,which was caused by different effects of sea reclamation modes on ESV evolution of muddy and bedrock bays.A negative effect of sea reclamation activities on bay ecosystem was ***,an attention should be paid to dynamic monitoring and early warning of development status in offshore areas,ecosystem-level reclamation control policy,and coastal wetland reserves ***,the spatial coupling mechanism study between bay ecosystem service demand and its service supply capacity should be strengthened to realize systematic regulation of bay ecological security pattern.

关键词： reclamation ecosystem service value correlation analysis bay East China Sea

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Extraction and back-extraction behaviors of 14 rare earth elements from sulfuric acid medium by TODGA

引用

Journal of Rare Earths 2018年第6期36卷 642-647页

作者： Huiting Yuan Weixiang Hong Yushan Zhou Baisong pu Aijun gong Tao Xu Qishan Yang Fukai Li Lina Qiu Weiwei Zhang Yuning Liu School of Chemistry and Biological engineering University of Science and Technology BeijingBeijing 100083China North China Rare Earth Hi-Tech Company Limited Baotou 014030China School of Chemistry and Chemical engineering Inner Mangolia University of Science and TechnologyBaotou 014010China

The unique physical and chemical properties of rare earth elements lay the foundation for their extensive application. N,N,N’,N’ Tetra-octyl-3-oxopentanediamide(TODGA) is excellent in its ability of extracting rare earth elements and it is favored for green initiative. In this paper, the extraction and back-extraction of14 rare earth elements by TODGA were studied. Experiments show that in conditions of 6 mol/L sulfuric acid, the extraction temperature of 25 ℃,the phase ratio of 1:1 and 0.04 mol/LTODGA(aviation kerosene as the diluent), the extraction rates of 14 rare earth elements including lanthanum, cerium, praseodymium,neodymium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, and yttrium were 99.00%-99.73%. Mixed with hydrochloric acid and nitric acid(HCl 3.5 mol/L, HNO30.5 mol/L), the recoveries of the 14 rare earth elements are 91.52%-99.91% when the extraction temperature is 25 ℃ and the ratio is 1:1. The following application is based on the optimum conditions above with practical samples(from the roasting production line of China North Rare Earth High-tech Company Limited) for extraction and back-extraction experiments. Experiments show that TODGA has excellent enrichment effect on 14 rare earth elements, the extraction rates are 91.36%-99.80%, the back-extraction rates are 87.29%-99.64% and the total recoveries are 81.19%-99.44%.

关键词： Rare earth Extraction Back-extraction N,N,N',N' Tetra-octyl-3-oxopentanediamide(TODGA) enrichment

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Evaluation of Genetic Diversity of Sichuan Common Wheat Landraces in China by SSR Markers

引用

Journal of Integrative Agriculture 2013年第9期12卷 1501-1511页

作者： LI Wei BIAN Chun-mei WEI Yu-ming LIU An-jun CHen Guo-yue pu Zhi-en LIU Ya-xi ZHenG You-liang Key Laboratory of Crop Genetic Resources and Improvement in Southwest China Ministry of EducationSichuan Agricultural University College of Agronomy Sichuan Agricultural University Triticeae Research Institute Sichuan Agricultural University

Genetic diversity of 62 Sichuan wheat landraces accessions of China was investigated by agronomic traits and SSR markers. The landrace population showed the characters of higher tiller capability and more kernels/spike, especially tiller no./plant of six accessions was over 40 and kernels/spike of three accessions was more than 70. A total of 547 alleles in 124 polymorphic loci were detected with an average of 4.76 alleles per locus by 114 SSR markers. Parameters analysis indicated that the genetic diversity ranked as genome A 〉 genome B 〉 genome D, and the homoeologous groups ranked as 5〉4〉3〉1〉2〉7〉6 based on genetic richness （Ri）. Furthermore, chromosomes 2A, 1B and 3D had more diversity than that of chromosomes 4A, 7A and 6B. The variation of SSR loci on chromosomes 1B, 2A, 2D, 3B, and 4B implied that, in the past, different selective pressures might have acted on different chromosome regions of these landraces. Our results suggested that Sichuan common wheat landraces is a useful genetic resource for genetic research and wheat improvement.

关键词： genetic diversity SSR marker landraces wheat

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Brief Exploration of Nasal Assimilation Phenomenonin Negative Prefixes-Comparison Between Chinese Dialect & english

引用

Journal of Literature and Art Studies 2022年第3期12卷 289-291页

作者： gong Yi-pu Chengdu College of University of Electronic Science and Technology of China ChengduChina

Nasals and assimilation are basic terminologies in phonology,nasal assimilation is a kind of common phonological phenomenon in *** is known to all,in english,assimilation mainly happens between consonants and consonants,which is one of the important constitutes of english mutation,for the sake of labor-saving convenience and better *** an applied linguistic view,nasal assimilation in negative prefixes(***-,ab-,ir-,im-&non-,etc.)is seemingly another interesting phenomenon for an innovative *** paper focuses on some specific enumeration and comparison between Chinese dialect(specifically,Sichuan dialect)as well as *** brief exploration and analysis might contribute to relative study in years to come.

关键词： nasal assimilation negative prefixes comparison Chinese dialect english

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：