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International Journal of Ophthalmology(english edition) 2022年第3期15卷 413-419页

作者： Bo Yu Yun-Hai Tu Guang-Ming Zhou Jie-Liang Shi en-de wu Wen-Can wu department of Orbital and Oculoplastic Surgery Eye Hospital of Wenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina

AIM: To demonstrate the outcomes of endoscopic endonasal dacryocystorhinostomy(en-DCR) with an novel lacrimal ostium stent(LOS) which was performed in patients with recurrent epiphora after failed external dacryocystorhinostomy(Ex-DCR) and analyze the causes of failed ***: From September 2015 and december 2017, the clinic data of 29 cases suffered from recurrent epiphora after failed Ex-DCR was *** LOS were implanted into the ostium at the end of the revisional *** causes of failed Ex-DCR were analyzed before revisional *** of revisional surgeries with the new device were evaluated as ***: The major causes of failure of the external approach were synechiae formation in the nasal ostium(29/29), followed by inadequate removal of the bony wall(21/29), nasal synechiae formation between lateral wall of nose and middle turbinate(11/29), and the bone opening was not in good location(7/29).The rate of success after revisional surgery was 82.76%.Re-obstruction of the ostiums were found in 5 failed ***: endoscopic approach with a novel LOS may be an effective procedure to manage recurrent epiphora after previous failed Ex-DCR *** formation in the nasal ostium and inadequate removal of the bony wall were the major causes of failure of Ex-DCR.

关键词： external dacryocystorhinostomy failed endoscopic technique lacrimal ostium stent

endoscopic transnasal canaliculorhinostomy for refractory common canalicular obstruction with an unidentifiable lacrimal sac

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International Journal of Ophthalmology(english edition) 2020年第8期13卷 1238-1243页

作者： Zhao-Qi Pan Jian-Ju Liu Xian-Ke Jia Jason Kian Seng Lee Yun-Hai Tu Jie-Liang Shi Bo Yu en-de wu Wen-Can wu The Mini-invasive Orbital&Oculoplastic Surgery Center Eye Hospital of Wenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina department of Ophthalmology the First Affiliated Hospital of Harbin Medical UniversityHarbin150000Heilongjiang ProvinceChina department of Ophthalmology the People’s Hospital of PingyangWenzhou 325400Zhejiang ProvinceChina Ophthalmology and Visual Sciences department Khoo Teck Puat Hospital999002Singapore

AIM:To describe the role of endoscopic transnasal canaliculorhinostomy(ETC)in refractory common canalicular obstruction(CCO)associated with an absent or unidentifiable lacrimal ***:The records of patients with refractory CCO who underwent ETC at the Eye Hospital of Wenzhou Medical University from October 2007 to december 2016 were retrospectively ***:Fifty-six patients(56 eyes)with refractory CCO were recruited into the *** patients were excluded due to the presence of a residual lacrimal sac or failure to complete the follow-up *** anatomic and functional success rates were both 85.4%(41/48)at a mean follow-up of 18.6 *** cases failed as a result of ostial synechia and two failed because of ostial obstruction by *** complications included mild nasal bleeding in 5 cases,dried nasal feeling in 8 cases,and olfactory dysfunction in 4 ***:Although being surgically challenging,ETC has comparable findings to its external approach counterpart or conjunctivodacryocystorhinostomy(CDCR)with Jones *** it may prove to be a novel alternate surgical technique for patients with refractory CCO without identifiable lacrimal sac.

关键词： refractory common canalicular obstruction endoscopic transnasal canaliculorhinostomy lacrimal reconstructive surgery

Extraordinary effects of liquid capsule application after resection of a giant meningioma

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Chinese Medical Journal 2008年第12期121卷 1140-1142页

作者： HU Yu-hua wu Jian-liang SHAO en-de wu Jian-ling JI Jian-wen department of Neurosurgery Second Hospital of Hebei Medical University Shijiazhuang Hebei 050000 China

Memnglomas are the second most common intracranial benign rumors and represent about15%-24% of primary brain tumors.1 Most meningiomas grow slowly at a rate of only 2.4 mm annually.2 Due to their slow growth, few clinical symptoms occur until the tumor reaches a large size. If the meningioma grows at the front or rear of the cranial cavity, it can grow to be very large before that area＇s vital functions are affected. Therefore, giant meningiomas are not infrequent, and actually account for 11.9% of meningiomas in our hospital. Because the volume of the giant meningioma is large,

关键词： giant meningioma resection liquid capsule complication

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非轴对称涡轮排气蜗壳优化设计

推进技术 2016年第10期37卷 1839-1846页

作者：黄恩德楚武利西北工业大学动力与能源学院陕西西安710129 先进航空发动机协同创新中心北京100191

为了改善涡轮排气蜗壳的气动性能,通过搭建NUCEMCA和Isight的集成优化平台,探索了一种多变量的优化方法,即对蜗壳参数化后,用优化的拉丁方试验设计获得空间均匀分布的试验样本,通过数值模拟求出各样本点性能参数,建立径向基神经网络代... 详细信息

为了改善涡轮排气蜗壳的气动性能,通过搭建NUCEMCA和Isight的集成优化平台,探索了一种多变量的优化方法,即对蜗壳参数化后,用优化的拉丁方试验设计获得空间均匀分布的试验样本,通过数值模拟求出各样本点性能参数,建立径向基神经网络代理模型(RBF),再运用自适应模拟退火算法(ASA)和直接搜索法(Hooke-Jeeves)得到最终的优化设计参数组合。结果表明,在不提高涡轮出口静压的前提下,在设计工况,优化后的蜗壳总压损失系数在原始蜗壳的基础上降低了9.82%,静压恢复系数最高提高了12.2%,出口速度分布也更加均匀,表明了优化系统的有效性。

关键词：排气蜗壳参数化试验设计径向基神经网络气动优化

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一种涡轮排气蜗壳的优化设计

航空动力学报 2017年第2期32卷 455-462页

作者：黄恩德楚武利董玮西北工业大学动力与能源学院西安710129 先进航空发动机协同创新中心北京100191

为了改善涡轮排气蜗壳的排气效果,选取一种箱式蜗壳为原始计算模型,通过数值模拟研究了该排气蜗壳的气动性能,揭示了蜗壳内部流动损失的主要来源,在不改变其几何尺寸的前提下,提出了一种蜗壳的分流层改型设计,并与两种一般改型方式的效... 详细信息

为了改善涡轮排气蜗壳的排气效果,选取一种箱式蜗壳为原始计算模型,通过数值模拟研究了该排气蜗壳的气动性能,揭示了蜗壳内部流动损失的主要来源,在不改变其几何尺寸的前提下,提出了一种蜗壳的分流层改型设计,并与两种一般改型方式的效果作比较.数值计算结果表明:在设计工况下,分流层改型设计可使排气蜗壳的总压损失系数最多降低32.12%,静叶恢复系数最多提高48.73%,其效果好于扩压结构弧线改型,但弱于蜗壳壁面轮廓型线改型,在此基础上揭示了分流层设计改善蜗壳气动性能的机理.

关键词：排气蜗壳分流层改型流动损失气动性能

Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases

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Neural Regeneration Research 2025年第1期20卷 6-20页

作者： Xiu-Yun Zhao de-en Xu Ming-Lei wu Ji-Chuan Liu Zi-Ling Shi Quan-Hong Ma department of Neurology and Clinical Research Center of Neurological Disease the Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Neuroscience&Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases Soochow UniversitySuzhouJiangsu ProvinceChina department of Neurology Jiangnan University Medical CenterWuxiJiangsu ProvinceChina

The endoplasmic reticulum,a key cellular organelle,regulates a wide variety of cellular *** reticulum autophagy,one of the quality control systems of the endoplasmic reticulum,plays a pivotal role in maintaining endoplasmic reticulum homeostasis by controlling endoplasmic reticulum turnover,remodeling,and *** this review,we briefly describe the endoplasmic reticulum quality control system,and subsequently focus on the role of endoplasmic reticulum autophagy,emphasizing the spatial and temporal mechanisms underlying the regulation of endoplasmic reticulum autophagy according to cellular *** also summarize the evidence relating to how defective or abnormal endoplasmic reticulum autophagy contributes to the pathogenesis of neurodegenerative *** summary,this review highlights the mechanisms associated with the regulation of endoplasmic reticulum autophagy and how they influence the pathophysiology of degenerative nerve *** review would help researchers to understand the roles and regulatory mechanisms of endoplasmic reticulum-phagy in neurodegenerative disorders.

关键词： autophagy endoplasmic reticulum endoplasmic reticulum autophagy endoplasmic reticulum quality control system endoplasmic reticulum receptors endoplasmic reticulum-associated degradation neurodegeneration neurodegenerative disease selective autophagy unfolded protein response

On the Variation of a Metric and Its Application

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Acta Mathematica Sinica,english Series 2010年第10期26卷 2003-2014页

作者： Fa en wu department of Mathematics School of Science Beijing Jiaotong University Beijing 100044 P. R. China

Some of the variation formulas of a metric were derived in the literatures by using the local coordinates system, In this paper, We give the first and the second variation formulas of the Riemannian curvature tensor, Ricci curvature tensor and scalar curvature of a metric by using the moving frame method. We establish a relation between the variation of the volume of a metric and that of a submanifold. We find that the latter is a consequence of the former. Finally we give an application of these formulas to the variations of heat invariants. We prove that a conformally flat metric g is a critical point of the third heat invariant functional for a compact 4-dimensional manifold M, then （M, g） is either scalar flat or a space form.

关键词： Riemannian functional variation of a metric volume variation space form heat invariant

Min-max partitioning problem with matroid constraint

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Journal of Zhejiang University-Science A(Applied Physics & engineering) 2008年第10期9卷 1446-1450页

作者： Biao wu en-yu YAO department of Mathematics Zhejiang University Hangzhou 310027 China

In this paper, we consider the set partitioning problem with matroid constraint, which is a generation of the k-partitioning problem. The objective is to minimize the weight of the heaviest subset. We present an approximation algorithm, which consists of two sub-algorithms-the modified Edmonds' matroid partitioning algorithm and the exchange algorithm, for the problem. An estimation of the worst ratio for the algorithm is given.

关键词： Matroid Matroid partition Worst ratio

Novel developments in computational spectropolarimeter

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Light(Science & Applications) 2023年第3期12卷 321-322页

作者： en-Lin Hsiang Shin-Tson wu College of Optics and Photonics University of Central FloridaOrlandoFL 32816USA

Compared to conventional bulky spectropolarimeters,computational spectropolarimeters which reconstruct light-field information such as polarization and spectrum in a compact form factor,are critical equipment enabling new *** key component of a computational spectropolarimeter is a tunable light-field modulator,in which liquid crystal-based device is a promising *** varying the applied voltage,the tunable liquid crystal metasurface can modulate the phase and spectral information of the incident light,and after a few trials,this important information can be decoded *** a novel approach paves the foundation for developing compact and low-cost spectropolarimetric imaging devices with widespread applications in biomedical imaging,remote sensing,and optical communications.

关键词： tunable polarization modulator

Lower bounds and modified LPT algorithm for k-partitioning problems with partition matroid constraint

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Applied Mathematics(A Journal of Chinese Universities) 2008年第1期23卷 1-8页

作者： wu Biao YAO en-yu dept. of Math. Zhejiang Univ. Hangzhou 310027 China.

In this paper, the k-partitioning problem with partition matroid constraint is considered. LPT algorithm is modified to fit the problem and its worst-ease performance is analyzed. The lower bounds of optimal solution ... 详细信息

关键词： partitioning constrained partition lower bound worst case ratio