检索结果-南通市图书馆

Hepatobiliary Surgery and Nutrition 2024年第2期13卷 311-313页

作者： Markos Kalligeros emmanuel A.Tsochatzis Division of Internal Medicine Warren Alpert Medical School of Brown UniversityRhode Island HospitalProvidenceRIUSA UCL Institute for Liver and Digestive Health Royal Free Hospital and UCLLondonUK Sheila Sherlock Liver Unit Royal Free HospitalLondonUK

Metabolic-dysfunction associated steatotic liver disease(MASLD),formerly known as non-alcoholic fatty liver disease(NAFLD)(1),is characterized by the accumulation of fat in the liver cells,independent of excessive alcohol consumption and has emerged as the most prevalent chronic liver condition in Western countries,underscoring a significant public health concern(2).The progression of MASLD to advanced fibrosis,marked by excessive extracellular matrix deposition and scar tissue formation,is a critical stage in MASLD natural history that significantly increases the risk of liver-related complications mortality(3).Non-invasive tests(NITs),such as liver stiffness measurement(LSM)with transient elastography(TE)and serum biomarkers,have gained prominence for assessing liver fibrosis in patients with suspected/confirmed NAFLD,offering a safer and less invasive alternative to liver biopsy(4).

关键词： Fibroscan enhanced liver fibrosis(ELF) fibrosis-4(FIB-4) cirrhosis metabolic-dysfunction associated steatotic liver disease(MASLD)

Assessment of ship maneuvering simulation with different propeller models

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2022年第3期34卷 422-433页

作者： Ganbo Deng Patrick Queutey Jeroen Wackers Michel Visonneau emmanuel Guilmineau Alban Leroyer LHEEA Lab Ecole Centrale de NantesNantesFrance

This paper is devoted to the assessment of ship maneuvering simulation using different propeller models with the focus on a simplified propeller model that represents the action of the propeller by body force and uses propeller performance curve to determine propeller loading during ship *** are also performed with an actual propeller approach with which the propeller rotation is simulated directly with the Reynolds averaged Navier-Stokes equation(RANSE)*** time accurate simulations using sliding grid and rotating frame approximations have been performed for *** zigzag and turning circle maneuvers in calm water have been simulated for two different ship models,namely the ONR tumblehome(ONRT)test case and the KRISO(Korea Research Institute of Ship and Ocean)Container Ship(KCS)test *** ship motion is compared with measurement data to assess the accuracy of the numerical prediction using RANSE computations with different propeller models.

关键词： Ship zigzag and turning circle motion simplified propeller model with body force actual propeller approach

Non-alcoholic fatty liver disease (NAFLD) and the quest for effective treatments

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary Surgery and Nutrition 2019年第1期8卷 77-79页

作者： Kessarin Thanapirom emmanuel A.Tsochatzis UCL Institute for Liver and Digestive Health Royal Free Hospital and UCLLondonUK Division of Gastroenterology Department of MedicineFaculty of MedicineChulalongkorn University and King Chulalongkorn Memorial HospitalThe Thai Red Cross SocietyBangkokThailand

Non-alcoholic fatty liver disease(NAFLD)is the most common cause of chronic liver disease worldwide,affecting 24%of the population,and is impacting on global public health care with a considerable financial burden(1).NAFLD encompasses a wide disease spectrum ranging from simple steatosis to non-alcoholic steatohepatitis(NASH),fibrosis and *** with simple steatosis typically do not develop liver-related complications,whereas patients with NASH are at increased risk of hepatic and extra-hepatic ***,NAFLD is associated with an increased risk of type 2 diabetes,cardiovascular disease and cancer(2).In addition,NASH is the second leading cause of cirrhosis in adult patients on the liver transplant waiting list in the United States(3,4).

关键词： NAFLD hepatic cirrhosis

Increased humic materials explain aggregate-protected carbon and nitrogen accumulation in biochar-amended tropical soils

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pedosphere 2024年第6期34卷 1086-1099页

作者： emmanuel AMOAKWAH Mohammad A.RAHMAN Khandakar R.ISLAM Kwame A.FRIMPONG Christian A.PHARES Louis SACKEY Isaac ASIRIFI emmanuel ARTHUR Council for Scientific and Industrial Research-Soil Research Institute Accra Center Soil Water and Bioenergy Resources The Ohio State University South Centers Department of Soil Science College of Agriculture and Natural Sciences School of Agriculture University of Cape Coast Ruhr-Universit?t Bochum Geographic Institute Department of Soil Science and Soil Ecology Department of Agroecology Faculty of Technical Sciences Arhus University

Humic materials make important contributions to soil organic carbon（C） and nitrogen（N） ***,information on the correlation between humic substances and the accumulation of soil aggregate-protected C and N in response to biochar application under tropical agroecosystems is ***,a field trial was conducted to elucidate the effects of biochar on soil aggregate properties and humic materials and how these humic compounds affect aggregate-protected C and N in a humid tropical *** treatments included no-biochar control（CK）,15 Mg biochar ha-1（BC-15）,30Mg biochar ha-1（BC-30）,and 30 Mg biochar ha-1+phosphate fertilizer（BC-30+P）.The treatments BC-30 and BC-30+P significantly increased the contents of humic materials（humic and fulvic acids） as compared to *** was a significant increase in the mean-weight diameter of soil aggregates by3-and 4-fold in BC-30 and BC-30+P,***,BC-30 and BC-30+P led to significant increases in soil structural coefficient by 3-and 4-fold,re spectively,relative to *** increases in organic C and N accumulation were observed in the macroaggregates of the biochar-amended *** relationships between the degree of polymerization and aggregate-protected C and N were observed,implying that low-molecular-weight aliphatic compounds favor organic C and N accumulation with biochar *** important soil property that contributed to organic C and N accumulation in aggregates was fulvic acid content,which could be used as an early and sensitive indicator to notice early changes in aggregate-protected C and N accumulation in soils of the humid tropics.

关键词： degree of humification fulvic acid humic acid macroaggregates soil structural coefficient

Pediatric NAFLD: lessons from the gut

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary Surgery and Nutrition 2020年第4期9卷 534-536页

作者： Laura Iogna Prat emmanuel A.Tsochatzis UCL Institute for Liver and Digestive Health Royal Free HospitalUniversity College of LondonLondonUK

Over the last decade numerous studies have focused on characterizing the human microbiome;particular attention has been paid to understanding the complex interplay between gut,its microbiota and the liver(the so called"gut-liver axis").The disruption of the gut-liver axis is involved in the development of several metabolic alterations such as obesity and non-alcoholic fatty liver disease(NAFLD)(1).

关键词： NAFLD alterations liver

Monotonic Diamond and DDFV Type Finite-Volume Schemes for 2D Elliptic Problems

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications in Computational Physics 2023年第7期34卷 456-502页

作者： Xavier Blanc Francois Hermeline emmanuel Labourasse Julie Patela UniversitéParis Cité Sorbonne UniversitéCNRSLaboratoire Jacques-Louis LionsF-75013 ParisFrance CEA DAMDIFF-91297 ArpajonFrance UniversitéParis-Saclay CEA DAM DIFLaboratoire en Informatique Haute Performance pour le Calcul et la Simulation91297 ArpajonFrance

The DDFV(Discrete Duality Finite Volume)method is a finite volume scheme mainly dedicated to diffusion problems,with some outstanding *** scheme has been found to be one of the most accurate finite volume methods for diffusion *** the present paper,we propose a new monotonic extension of DDFV,which can handle discontinuous tensorial diffusion ***,we compare its performance to a diamond type method with an original interpolation method relying on polynomial *** is achieved by adapting the method of Gao et al[A finite volume element scheme with a monotonicity correction for anisotropic diffusion problems on general quadrilateral meshes]to our *** a technique does not require the positiveness of the secondary *** show that the two new methods are second-order accurate and are indeed monotonic on some challenging benchmarks as a Fokker-Planck problem.

关键词： Finite volume method anisotropic diffusion monotonic method DDFV scheme

CA-KSE: a combinatorial algorithm for benchmarking in knowledge sharing environment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Intelligent Computing and Cybernetics 2019年第1期12卷 2-22页

作者： Femi emmanuel Ayo Olusegun Folorunso Sakinat Oluwabukonla Folorunso Department of Computer Science Federal University of AgricultureAbeokutaNigeria Department of Physical and Computer Sciences McPherson UniversitySeriki SotayoNigeria Department of Computer Science College of Physical SciencesFederal University of AgricultureAbeokutaNigeria Department of Mathematical Sciences Olabisi Onabanjo UniversityAgo IwoyeNigeria

Purpose–Over the past decade,the cost of product development has increased drastically,and this is due to the inability of most enterprises to locate suitable and optimal collaborators for knowledge ***,knowledge sharing is a mechanism that helps people find the best collaborators with relevant ***,a new approach for locating optimal collaborators with relevant knowledge is needed,which couldhelp enterprisein reducingcost andtime ina *** aimsto discuss these ***/methodology/approach–One unique challenge in the domain of knowledge sharing is that collaborators do not possess the same number of events resident in the knowledge available for *** this paper,the authors present a new approach for locating optimal collaborators in knowledge-sharing environment using the combinatorial algorithm(CA-KSE).Findings–The proposed pattern-matching approach implemented in Java is considered efficient for solving the issue peculiar to collaboration in knowledge-sharing *** authors benchmarked the proposed approach with its semi-global pairwise alignment and global alignment counterparts through scores comparison and the receiver operating characteristic *** results obtained from the comparisons showedthat CA-KSEis a perfect test havinganarea undercurveof 0.9659,comparedto the other *** limitations/implications–The paper has proposed an efficient algorithm,which is considered better than related methods,for matching several collaborators(more than two)in KS *** method could be deployed in medical field for gene analysis,software organizations for distributed development and academics for knowledge ***/value–One sign of strength of this approach,compared to most sequence alignment approaches that can only match two collaborators at a time,is that it can match several collaborators at a faster rate.

关键词： Combinatorial algorithm Knowledge sharing(KS) Collaborators Pattern matching,Benchmark score

The bold sedentary behavior recommendations in the new Canadian guidelines: are they evidence-based? Response to “Sedentary Behavior Research Network members support new Canadian 24-Hour Movement Guideline recommendations”

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2020年第6期9卷 482-484页

作者： emmanuel Stamatakis Adrian E.Bauman Charles Perkins Centre Faculty of Medicine and HealthSchool of Health SciencesUniversity of SydneySydneyNSW 2006Australia Charles Perkins Centre Faculty of Medicine and HealthSchool of Public HealthPrevention Research CollaborationUniversity of SydneySydneyNSW 2006Australia

Dear editor,We read with interest the commentary by Mark Tremblay and colleagues,1 which outlines the new 24-Hour Canadian sedentary behavior *** guidelines take the perspective of a continuum across the 24-h day,providing a vehicle for discussing physically active time,sitting and other sedentary time,as well as healthy sleep *** commentary 1 focuses on the sedentary behavior(SB)recommendations in these guidelines:(1)limiting sedentary time to8 h per day,(2)limiting recreational screen time to3 h,and(3)breaking up long periods of sitting as often as possible throughout the *** for this perspective was evidenced by a survey of a sample(n=126,6% of total)of Sedentary Behavior Research Network(SBRN)members2 indicating broad acceptance of these SB recommendations.1 In this response,we put this survey in context and discuss the evidence base underpinning these 3 Canadian sedentary-behavior recommendations.

关键词： limiting Canadian editor

Comparative assessment of agricultural technology generating practices in universities and research institutes in north central zone of Nigeria

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Information Processing in Agriculture 2017年第2期4卷 161-167页

作者： Gbolagade Benjamin Adesiji Mohammed Ibrahim Sola emmanuel Komolafe Department of Agricultural Extension and Rural Development University of IlorinP.M.B.1515IlorinKwara StateNigeria Department of Agricultural Economics and Extension Technology Federal University of TechnologyMinnaNiger StateNigeria

To understand the technology generating practices among universities and research institutes in north central zone of Nigeria,this study examined sources of funds for technology generating activities,compared agro-technology generating practices and identified constraining factors hindering technology generating *** hundred and fifty-two academic staff were randomly selected from universities and one hundred and thirty-six respondents were drawn from research *** questionnaires with reliability coefficient of r=0.92 were used to elicit *** were analyzed using descriptive statistics,Likert-scale,T-test and Factor ***(93.4%)of universities’respondents used their personal funds to generate new technology compared to their counterparts in research *** most widely employed mechanism for generating agricultural technologies was joint radio programmes(mean=3.38)while the least was biotechnology(mean=2.57).Major areas of differences in technology generation between the two institutions were the physical distance(t=13.54;P<0.05),farmers participation in field research trials(t=8.50;P<0.05),farmers co-finance of adaptive research trials(t=3.77;P<0.05)and adequate research facilities and incentives to workers(t=2.05;P<0.05).Factors constraining technology generation for universities were poor access to knowledge and information on new innovation(r=0.815)while for research institutes it was limited physical resources(ICT,Telephone)(r=0.801).It was recommended therefore that respondents should look into options of writing alternate fund proposals and submitting to a wider range of funding *** of innovation could be strengthened through the formation of a formal technological linkage advisory council.

关键词： Technology Constraining factor Linkage practice Funding sources

Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第39期21卷 11044-11052页

作者： Rosa Lombardi Elena Buzzetti Davide Roccarina emmanuel A Tsochatzis Sheila Sherlock Liver Unit and UCL Institute for Liver and Digestive Health Royal Free Hospital and UCL

Alcoholic liver disease(ALD) consists of a broad spectrum of disorders, ranging from simple steatosisto alcoholic steatohepatitis and cirrhosis. Fatty liver develops in more than 90% of heavy drinkers, however only 30%-35% of them develop more advanced forms of ALD. Therefore, even if the current "gold standard" for the assessment of the stage of alcohol-related liver injury is histology, liver biopsy is not reasonable in all patients who present with ALD. Currently, although several non-invasive fibrosis markers have been suggested as alternatives to liver biopsy in patients with ALD, none has been sufficiently validated. As described in other liver disease, the diagnostic accuracy of such tests in ALD is acceptable for the diagnosis of significant fibrosis or cirrhosis but not for lesser fibrosis stages. Existing data suggest that the use of noninvasive tests could be tailored to first tier screening of patients at risk, in order to diagnose early patients with progressive liver disease and offer targeted interventions for the prevention of decompensation. We review these tests and critically appraise the existing evidence.

关键词： Transient elastography Cirrhosis Prognosis Histolo